Results for the protein: NP

Results for the Protein: NP_001073594

122056476

841

CASP8

NCBI

caspase-8 isoform G precursor [Homo sapiens]

Known Diseases associated with this Protein:
BREAST CANCER, PROTECTION AGAINST
CASPASE 8 DEFICIENCY

2

3

2

3

0

Tips:

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
DED_PEA15	cd08338	0.00014	60	143
DED_c-FLIP_repeat2	cd08340	0.001	60	137
DED_Caspase_10_repea	cd08341	6.7e-08	60	142
DED	cd00045	6.4e-15	62	138
DED_Caspase_8_repeat	cd08333	3.1e-54	62	143
DED_Caspase-like_rep	cd08776	1.8e-21	62	138
DED_Caspase_8_10_rep	cd08792	9.1e-26	62	138
DED_c-FLIP_repeat1	cd08337	0.00018	63	146
DED_Caspase_8_10_rep	cd08334	5e-44	157	239
DED_Caspase_8_repeat	cd08813	2e-62	157	239
DED_Caspase_10_repea	cd08814	5.3e-09	157	239
DED_Caspase-like_rep	cd08775	7.7e-49	158	237
CASc	cd00032	2.1e-132	284	536
DED	pfam01335	1.4e-34	62	145
DED	pfam01335	9.5e-27	160	242
Peptidase_C14	pfam00656	2.3e-94	293	535
DED	smart00031	1.3e-32	60	139
DED	smart00031	3e-27	158	237
CASc	smart00115	9.7e-141	285	537

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1045485	Polymorphism	p.ASP344HIS	N/A
dbSNP	rs3769823	Polymorphism	p.LYS14ARG	N/A
dbSNP	rs3769824	Polymorphism	p.MET1THR	N/A
OMIM	601763.0001	Disease	p.ARG248TRP	CASPASE 8 DEFICIENCY
OMIM	601763.0003	Disease	p.ASP302HIS	BREAST CANCER, PROTECTION AGAINST

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