Results for the protein: Q99665

Results for the Protein: Q99665

12229836

3595

IL12RB2

NCBI, UniProt

I12R2_HUMAN RecName: Full=Interleukin-12 receptor subunit beta-2; Short=IL-12 receptor subunit beta-2; Short=IL-12R subunit beta-2; Short=IL-12R-beta-2; Short=IL-12RB2; Flags: Precursor

			0 12 0 6 6

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: Lep_receptor_Ig - pfam06328 IL6Ra-bind - pfam09240 FN3 - cd00063 FN3 - smart00060 fn3 - pfam00041	Swiss-Prot Protein: Q99665 Identical to: NP_001550 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
FN3	cd00063	6.7e-08	421	520
FN3	cd00063	3.9e-10	522	617
fn3	pfam00041	6e-05	422	510
fn3	pfam00041	0.00048	519	608
Lep_receptor_Ig	pfam06328	5.6e-38	27	111
IL6Ra-bind	pfam09240	0.00025	128	221
FN3	smart00060	0.0001	224	303
FN3	smart00060	6.1e-07	421	510
FN3	smart00060	1.1e-07	519	607

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs2307154	Polymorphism	p.ALA625VAL	N/A
dbSNP	rs17129792	Polymorphism	p.ARG149GLN	N/A
Swiss-Prot	VAR_019526	Polymorphism	p.ARG313GLY	N/A
dbSNP	rs2307145	Polymorphism	p.GLN426HIS	N/A
dbSNP	rs2307148	Polymorphism	p.GLY420ARG	N/A
dbSNP	rs2307153	Polymorphism	p.GLY465ASP	N/A
Swiss-Prot	VAR_049169	Polymorphism	p.GLY420SER	N/A
Swiss-Prot	VAR_019527	Polymorphism	p.HIS720ARG	N/A
Swiss-Prot	VAR_014805	Polymorphism	p.ILE185VAL	N/A
Swiss-Prot	VAR_021280	Polymorphism	p.LEU808ARG	N/A
dbSNP	rs17129772	Polymorphism	p.MET13VAL	N/A
Swiss-Prot	VAR_019525	Polymorphism	p.THR201ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258