Results for the protein: Q9P0L2

Results for the Protein: Q9P0L2

124056494

4139

MARK1

NCBI, UniProt

MARK1_HUMAN RecName: Full=Serine/threonine-protein kinase MARK1; AltName: Full=MAP/microtubule affinity-regulating kinase 1; AltName: Full=PAR1 homolog c; Short=Par-1c; Short=Par1c

			0 6 0 0 6

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: Q9P0L2

Identical to: NP_061120

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	6.8e-12	14	367
STKc_ROCK1	cd05622	1.9e-10	22	368
STKc_TAO1	cd06635	1.7e-07	33	364
STKc_PAK5	cd06658	4.4e-12	34	328
STKc_PAK6	cd06659	1.4e-13	35	334
STKc_JNK1	cd07875	6.3e-08	35	353
STKc_PAK1	cd06654	4.6e-17	36	334
STKc_PAK4	cd06657	1e-13	36	330
STKc_PAK	cd06614	3.4e-23	37	324
STKc_TAO3	cd06633	1.5e-05	37	364
STKc_PAK_I	cd06647	1e-24	37	332
STKc_PAK_II	cd06648	5.8e-16	37	324
STKc_PAK2	cd06655	1.7e-18	37	335
STKc_PAK3	cd06656	6.8e-14	37	335
STKc_JNK2	cd07876	8.2e-10	38	355
PTKc_DDR	cd05051	2.2e-06	39	309
PTKc_DDR1	cd05096	0.00032	39	315
PTKc_DDR2	cd05095	4.5e-06	39	311
PTKc_DDR_like	cd05097	3.2e-05	39	311
STKc_myosinIIIB	cd06639	4.2e-08	39	312
STKc_myosinIIIA	cd06638	6.3e-10	40	311
STKc_p38alpha_MAPK14	cd07877	4.3e-07	40	366
STKc_CDK10	cd07845	5.9e-12	41	326
PTKc_PDGFR	cd05055	0.00045	42	313
STKc_MAP4K4_6	cd06636	2.2e-07	42	311
STKc_JNK	cd07850	3.9e-10	43	353
STKc_p38	cd07851	5.2e-11	43	346
STKc_p38delta_MAPK13	cd07879	7.8e-05	43	354
STKc_TAO	cd06607	1.5e-07	44	341
STKc_p38beta_MAPK11	cd07878	5.3e-07	44	366
STKc_p38gamma_MAPK12	cd07880	9.1e-09	44	366
PTKc_FGFR1	cd05098	6.4e-07	45	318
STKc_JNK3	cd07874	2.4e-09	46	355
PKc_MKK7	cd06618	2.9e-10	47	336
PTKc_FGFR4	cd05099	4.7e-08	48	329
PTKc_FGFR2	cd05101	2.9e-07	48	318
STKc_MAP4K5	cd06646	8.1e-11	49	310
PTK_Ryk	cd05043	2.8e-05	50	282
PTKc_FGFR	cd05053	8.8e-09	50	312
PTKc_FGFR3	cd05100	2.7e-06	50	347
STKc_MAP4K3	cd06645	6.5e-10	50	310
STKc_STK10_LOK	cd06644	8.9e-11	50	330
STKc_ASK	cd06624	3.5e-23	51	311
PTKc_EGFR_like	cd05057	2.6e-07	52	314
PTKc_Src_like	cd05034	1.6e-11	53	305
PTKc_Musk	cd05050	2.3e-09	53	309
PTKc_Jak_rpt2	cd05038	1.5e-11	53	313
PTKc_InsR	cd05061	6.1e-06	53	322
PTKc_IGF-1R	cd05062	5.6e-05	53	308
PTKc_Lck_Blk	cd05067	3.9e-07	53	330
PTKc_Fyn_Yrk	cd05070	1.4e-08	53	309
PTKc_Src	cd05071	1.4e-08	53	311
PTKc_Lyn	cd05072	2.4e-09	53	310
PTKc_Hck	cd05073	3.2e-09	53	309
PTKc_Jak2_Jak3_rpt2	cd05081	2.8e-09	53	311
PTKc_Ror1	cd05090	5.2e-07	53	310
PTKc_Yes	cd05069	1.1e-09	53	309
PTKc_Srm_Brk	cd05148	4.9e-11	53	313
STKc_SLK_like	cd06611	2.2e-13	53	325
STKc_TNIK	cd06637	5.1e-09	53	311
STKc_CDK12	cd07864	3e-13	53	311
STKc_CDK9	cd07865	7.5e-13	53	311
PTKc_Ror	cd05048	4.3e-09	54	310
PTKc_EphR_A2	cd05063	1.2e-06	54	311
PTKc_EphR_A10	cd05064	7.5e-08	54	313
PTKc_Ror2	cd05091	1.6e-05	54	310
STKc_TAO2	cd06634	6.7e-08	54	346
STKc_MST4	cd06640	1.1e-08	54	314
STKc_MST3	cd06641	2.6e-09	54	311
STKc_STK25-YSK1	cd06642	1.4e-09	54	314
STKc_SLK	cd06643	4.6e-11	54	326
PKc_MEK2	cd06649	1.4e-05	54	393
PTKc_ALK_LTK	cd05036	2.2e-08	55	307
PTK_Jak1_rpt1	cd05077	3e-06	55	310
STKc_MAPK15	cd07852	2.9e-13	55	340
PTKc_EphR	cd05033	2.7e-09	56	311
PTK_CCK4	cd05046	8.9e-06	56	308
PTKc_Trk	cd05049	6.1e-09	56	290
PTKc_Abl	cd05052	6.1e-11	56	313
PTKc_Tec_like	cd05059	6.2e-12	56	292
PTKc_EphR_A	cd05066	2.1e-07	56	311
PTKc_EphR_B	cd05065	1.7e-07	56	311
PTKc_Frk_like	cd05068	2.2e-16	56	309
PTKc_Tyk2_rpt2	cd05080	2.8e-08	56	315
PTKc_Csk	cd05082	1.6e-20	56	313
PTKc_Tie2	cd05088	2.5e-09	56	338
PTKc_TrkA	cd05092	1e-06	56	319
PTKc_TrkB	cd05093	1e-06	56	332
PTKc_TrkC	cd05094	1.1e-05	56	369
PTKc_Chk	cd05083	4.4e-15	56	308
PTKc_EGFR	cd05108	1.7e-06	56	355
PTKc_HER2	cd05109	1.1e-05	56	314
PTKc_HER4	cd05110	3.7e-05	56	319
PTK_HER3	cd05111	7.8e-07	56	321
PTKc_Itk	cd05112	8.9e-11	56	310
PTKc_Btk_Bmx	cd05113	6.8e-16	56	310
PTKc_Tec_Rlk	cd05114	4.8e-11	56	310
PKc_MAPKK_Byr1_like	cd06620	2.3e-08	56	324
PKc_MEK1	cd06650	9e-05	56	397
STKc_PCTAIRE_like	cd07844	3.4e-19	56	358
STKc_ERK1_2_like	cd07849	6.3e-09	56	363
STKc_ERK5	cd07855	6.7e-12	56	356
STKc_Sty1_Hog1	cd07856	1e-09	56	346
STKc_BUR1	cd07866	3.7e-14	56	311
STKc_PFTAIRE1	cd07869	1.5e-06	56	351
STKc_PCTAIRE3	cd07871	8.3e-11	56	311
STKc_PCTAIRE2	cd07872	6.4e-09	56	326
STKc_PCTAIRE1	cd07873	6.1e-09	56	323
STKc_PFTAIRE2	cd07870	2e-08	56	358
PTKc_FAK	cd05056	4.9e-10	57	318
PTKc_Tie1	cd05089	3.1e-08	57	337
STKc_CDC2L1	cd07843	4e-14	57	311
STKc_CDC2L6	cd07867	3.5e-06	57	311
STKc_CDK8	cd07868	2.5e-06	57	311
STKc_Nek6	cd08228	2.6e-11	57	313
STKc_Nek7	cd08229	8e-12	57	313
STKc_Nek6_Nek7	cd08224	3.7e-12	57	313
STKc_ROCK_NDR_like	cd05573	6.3e-15	58	359
STKc_phototropin_lik	cd05574	1.3e-15	58	324
STKc_PKA	cd05580	1.3e-24	58	336
STKc_PDK1	cd05581	7.2e-49	58	311
STKc_DMPK_like	cd05597	1.6e-12	58	366
STKc_LATS	cd05598	1.2e-08	58	373
STKc_Sid2p_Dbf2p	cd05600	2.6e-11	58	371
STKc_CRIK	cd05601	5.4e-13	58	366
STKc_MAST	cd05609	9.3e-25	58	367
STKc_PRKX_like	cd05612	4.1e-44	58	340
STKc_MRCK_alpha	cd05623	3.3e-10	58	367
STKc_MRCK_beta	cd05624	1.1e-09	58	366
STKc_LATS1	cd05625	2.8e-06	58	373
STKc_LATS2	cd05626	2.2e-05	58	373
STKc_NDR2	cd05627	6.5e-07	58	423
STKc_NDR_like_fungal	cd05629	5.9e-08	58	376
STKc_NDR1	cd05628	1.1e-08	58	369
PKc_MAPKK	cd06605	1.4e-13	58	317
STKc_MST3_like	cd06609	3.9e-16	58	331
STKc_OSR1_SPAK	cd06610	1.8e-15	58	311
STKc_myosinIII_like	cd06608	1.6e-11	58	311
PKc_MEK	cd06615	1.2e-08	58	328
PKc_MKK5	cd06619	6.9e-05	58	321
PKc_MAPKK_PBS2_like	cd06622	3.3e-09	58	371
PKc_MAPKK_plant_like	cd06623	2.5e-19	58	316
STKc_MEKK2	cd06652	5.3e-16	58	312
STKc_NAK1_like	cd06917	2.7e-14	58	324
STKc_CDKL	cd07833	2.6e-14	58	311
STKc_CdkB_plant	cd07837	1.3e-14	58	312
STKc_CDKL2_3	cd07846	4e-11	58	311
STKc_CDKL1_4	cd07847	8.1e-24	58	344
STKc_CDKL5	cd07848	6.5e-07	58	311
STKc_MAPK4_6	cd07854	1e-07	58	349
STKc_TEY_MAPK_plant	cd07858	3.2e-09	58	358
STKc_CDK6	cd07862	3.8e-05	58	311
SPS1	COG0515	1.5e-76	58	494
PTKc_InsR_like	cd05032	6.2e-10	59	308
PTKc_RET	cd05045	8.7e-08	59	316
PTKc_Jak1_rpt2	cd05079	5.5e-07	59	313
PKc_STE	cd05122	2e-41	59	310
STKc_Yank1	cd05578	2.4e-26	59	311
STKc_MSK_N	cd05583	1.1e-29	59	326
STKc_GRK4_like	cd05605	2e-13	59	328
STKc_cPKC	cd05587	9.4e-31	59	370
STKc_MSK1_N	cd05613	3e-20	59	332
STKc_MSK2_N	cd05614	8e-24	59	383
STKc_cPKC_alpha	cd05615	5.5e-19	59	367
STKc_GRK6	cd05630	4e-09	59	328
STKc_GRK4	cd05631	4.1e-09	59	328
STKc_GRK5	cd05632	1.1e-09	59	328
STKc_cPKC_beta	cd05616	1.9e-18	59	369
STKc_MAPKKK	cd06606	1.4e-41	59	311
STKc_MAP4K3_like	cd06613	6e-16	59	310
STKc_MEKK3_like	cd06625	4.7e-30	59	311
STKc_Cdc7_like	cd06627	1.2e-20	59	311
STKc_MEKK1	cd06630	1.1e-10	59	312
STKc_YSK4	cd06631	3.7e-10	59	311
STKc_MAPKKK_Byr2_lik	cd06628	3.4e-27	59	311
STKc_MEKK3	cd06651	1.3e-21	59	313
STKc_MEKK3_like_1	cd06653	2.3e-19	59	312
STKc_CCRK	cd07832	6.9e-16	59	312
STKc_Pho85	cd07836	8.3e-25	59	358
STKc_CDK5	cd07839	2.1e-11	59	311
STKc_CDK7	cd07841	6.1e-18	59	321
STKc_CDK8_like	cd07842	5.3e-11	59	311
STKc_MAPK	cd07834	7.2e-15	59	346
STKc_NLK	cd07853	4e-11	59	378
STKc_MPK1	cd07857	3.3e-09	59	349
STKc_TDY_MAPK_plant	cd07859	2e-09	59	366
STKc_CDK2_3	cd07860	2.9e-21	59	311
STKc_CDK1_euk	cd07861	1.6e-21	59	311
STKc_CDK4	cd07863	1.9e-07	59	311
STKc_Nek	cd08215	1.5e-66	59	311
STKc_Nek2	cd08217	3.4e-29	59	311
STKc_Nek1	cd08218	2.3e-36	59	311
STKc_Nek3	cd08219	8.8e-28	59	311
STKc_Nek8	cd08220	1.7e-38	59	311
STKc_Nek9	cd08221	5.8e-17	59	311
STKc_Nek11	cd08222	4.3e-22	59	311
STKc_Nek4	cd08223	1.5e-26	59	311
STKc_Nek5	cd08225	6.9e-32	59	311
STKc_Nek10	cd08528	3.1e-10	59	308
STKc_FA2-like	cd08529	3e-17	59	302
STKc_CNK2-like	cd08530	8.8e-16	59	311
PTKc_Axl_like	cd05035	1.5e-06	60	306
PTKc_Tyro3	cd05074	2.8e-07	60	313
PTKc_Axl	cd05075	3.1e-05	60	313
STKc_CMGC	cd05118	3.1e-19	60	311
STKc_PKN	cd05589	4.8e-25	60	368
STKc_MST1_2	cd06612	2.6e-18	60	311
STKc_MAK_like	cd07830	1.5e-16	60	311
STKc_MOK	cd07831	6.4e-13	60	311
STKc_CDK_like	cd07829	4e-24	60	311
STKc_CDK1_like	cd07835	1.3e-18	60	311
STKc_CDK4_6_like	cd07838	1e-12	60	311
STKc_CDK9_like	cd07840	3.3e-20	60	311
PTKc_Csk_like	cd05039	1.6e-12	61	294
STKc_MEKK4	cd06626	5.3e-17	61	311
STKc_MEKK1_plant	cd06632	5.3e-13	61	311
PK_STRAD	cd08216	1.8e-07	61	326
PK_STRAD_beta	cd08226	1.3e-05	61	373
PK_STRAD_alpha	cd08227	7.6e-05	61	392
STKc_RSK_N	cd05582	9.1e-29	63	368
STKc_p70S6K	cd05584	3.6e-32	63	370
PTKc	cd00192	2e-18	64	310
PTK_Jak_rpt1	cd05037	0.00074	64	310
PTKc_Ack_like	cd05040	1e-13	64	311
PTKc_Fes_like	cd05041	2.2e-16	64	311
PTKc_Aatyk	cd05042	2.2e-07	64	294
PTKc_c-ros	cd05044	8.1e-06	64	312
PTKc_Tie	cd05047	6.7e-08	64	312
PTKc_Met_Ron	cd05058	1.3e-06	64	315
PTKc_Syk_like	cd05060	8.9e-12	64	311
PTK_Jak2_Jak3_rpt1	cd05078	1.4e-06	64	312
PTKc_Fes	cd05084	6.7e-22	64	311
PTKc_Fer	cd05085	3e-14	64	311
PTKc_Aatyk2	cd05086	4.2e-05	64	311
PTKc_Aatyk1_Aatyk3	cd05087	0.00027	64	311
PTKc_Syk	cd05116	2.1e-13	64	315
STKc_PKC	cd05570	5e-22	64	359
STKc_SGK	cd05575	6.6e-21	64	366
STKc_PKB	cd05571	1.2e-40	64	373
STKc_aPKC	cd05588	2.1e-26	64	382
STKc_nPKC_eta	cd05590	6.8e-35	64	356
STKc_nPKC_epsilon	cd05591	1.4e-32	64	369
STKc_PKB_gamma	cd05593	1.3e-27	64	383
STKc_PKB_alpha	cd05594	2.4e-28	64	371
STKc_PKB_beta	cd05595	1.9e-33	64	383
STKc_NDR_like	cd05599	7.4e-09	64	348
STKc_nPKC_theta_delt	cd05592	5.7e-36	64	370
STKc_SGK1	cd05602	9.9e-21	64	373
STKc_SGK2	cd05603	1.5e-21	64	374
STKc_SGK3	cd05604	1.9e-20	64	373
STKc_aPKC_zeta	cd05617	5.7e-13	64	382
STKc_aPKC_iota	cd05618	3.3e-16	64	382
STKc_nPKC_theta	cd05619	4.7e-31	64	370
STKc_nPKC_delta	cd05620	1.7e-22	64	370
STKc_Rim15_like	cd05611	8.8e-09	64	308
PKc_MKK3_6	cd06617	6.3e-10	64	325
PTKc_Zap-70	cd05115	4.1e-09	65	311
STKc_beta_ARK	cd05606	3.9e-12	65	328
STKc_GRK3	cd05633	1.5e-09	65	333
PKc_MKK4	cd06616	3.2e-09	65	324
PKc_MAPKK_Pek1_like	cd06621	1.5e-11	65	320
PKc	cd00180	4.3e-92	66	309
STKc_AGC	cd05123	1.2e-65	66	311
STKc_cGK_PKG	cd05572	3.2e-35	66	317
STKc_GRK	cd05577	1.7e-13	66	327
STKc_MAST_like	cd05579	1.2e-28	66	316
STKc_Sck1_like	cd05586	3.4e-27	66	427
STKc_GRK7	cd05607	2.2e-09	66	327
STKc_GRK1	cd05608	3.9e-21	66	327
STKc_YPK1_like	cd05585	2.4e-27	66	367
STKc_MAPKKK_Bck1_lik	cd06629	3.4e-13	66	311
UBA	cd00194	1.2e-08	332	369
Pkinase	pfam00069	2.4e-101	60	311
UBA	pfam00627	1.9e-05	331	367
KA1	pfam02149	9.9e-23	750	795
Pkinase_Tyr	pfam07714	3.2e-19	60	309
TyrKc	smart00219	8.1e-23	60	309
STYKc	smart00221	7.7e-102	60	311
S_TKc	smart00220	4.3e-110	70	311
KIND	smart00750	6.5e-05	142	319
UBA	smart00165	7.1e-10	332	368

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_030018	Polymorphism	p.ARG645GLY	N/A
Swiss-Prot	VAR_040761	Polymorphism	p.ASN355THR	N/A
Swiss-Prot	VAR_040764	Polymorphism	p.GLU691GLY	N/A
Swiss-Prot	VAR_040763	Polymorphism	p.PRO578LEU	N/A
Swiss-Prot	VAR_040760	Polymorphism	p.TYR233CYS	N/A
Swiss-Prot	VAR_040762	Polymorphism	p.VAL530MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258