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Results for the Protein: P08887
124343

IL6RA_HUMAN RecName: Full=Interleukin-6 receptor subunit alpha; Short=IL-6 receptor subunit alpha; Short=IL-6R subunit alpha; Short=IL-6R-alpha; Short=IL-6RA; AltName: Full=IL-6R 1; AltName: Full=Membrane glycoprotein 80; Short=gp80; AltName: CD_antigen=CD126; Flags: Precursor

Known Diseases associated with this Protein:
  INTERLEUKIN 6, SERUM LEVEL OF, QUANTITATIVE T
  LOCUS
  SOLUBLE INTERLEUKIN-6 RECEPTOR, SERUM LEVEL OF, QUANTITATIVE TRAIT
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Default View:

IG - smart00409
IG_like - smart00410
IGc2 - smart00408
ig - pfam00047
IL6Ra-bind - pfam09240
FN3 - smart00060
FN3 - cd00063


Swiss-Prot Protein: P08887
Identical to: NP_000556
   Default View:






Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
FN3cd000634.4e-08216311
igpfam000471.6e-054098
IGsmart004090.0007132113
IG_likesmart004100.0005932113
IGc2smart004087.4e-1539103
IL6Ra-bindpfam092403e-33115213
FN3smart000602.9e-08216301

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs2228145 Polymorphismp.ASP358ALAN/A
dbSNPrs2228146 Polymorphismp.VAL385ILEN/A
OMIM147880.0001 Diseasep.ASP358ALASOLUBLE INTERLEUKIN-6 RECEPTOR, SERUM LEVEL OF, QUANTITATIVE TRAIT||LOCUS||INTERLEUKIN 6, SERUM LEVEL OF, QUANTITATIVE T



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