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Results for the Protein: P06241
125370
FYN

FYN_HUMAN RecName: Full=Tyrosine-protein kinase Fyn; AltName: Full=Proto-oncogene Syn; AltName: Full=Proto-oncogene c-Fyn; AltName: Full=Src-like kinase; Short=SLK; AltName: Full=p59-Fyn
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4
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4
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

SH3 - smart00326
SH3 - cd00174
SH3_2 - pfam07653
SH3_1 - pfam00018
PTKc_Kit - cd05104
SH2 - smart00252
SH2 - cd00173
SH2 - pfam00017
PTKc_VEGFR - cd05054
PTKc_CSF-1R - cd05106
PTKc_PDGFR_beta - cd05107
PTKc_PDGFR - cd05055
PTKc_PDGFR_alpha - cd05105
STKc_myosinIIIB - cd06639
STKc_TAO1 - cd06635
PTK_Tyk2_rpt1 - cd05076
STKc_PAK4 - cd06657
STKc_PAK5 - cd06658
STKc_PAK6 - cd06659
STKc_PAK_II - cd06648
STKc_TAO3 - cd06633
STKc_myosinIIIA - cd06638
STKc_p38alpha_MAPK14 - cd07877
STKc_STK10_LOK - cd06644
PTKc_FGFR1 - cd05098
STKc_p38 - cd07851
STKc_PAK - cd06614
STKc_PAK3 - cd06656
STKc_PAK_I - cd06647
STKc_PAK1 - cd06654
STKc_PAK2 - cd06655
STKc_TAO2 - cd06634
STKc_TAO - cd06607
PTKc_FGFR2 - cd05101
STKc_MAP4K3 - cd06645
STKc_MAP4K4_6 - cd06636
PTKc_FGFR3 - cd05100
PTKc_FGFR4 - cd05099
PTKc_FGFR - cd05053
PKc_MKK7 - cd06618
STKc_p38beta_MAPK11 - cd07878
STKc_MAP4K5 - cd06646
STKc_CDK9 - cd07865
PTKc_VEGFR2 - cd05103
STKc_BUR1 - cd07866
STKc_Sty1_Hog1 - cd07856
PTKc_VEGFR3 - cd05102
PTKc_EGFR_like - cd05057
PTKc_HER4 - cd05110
PTKc_EGFR - cd05108
PTKc_HER2 - cd05109
PTKc_Chk - cd05083
PTKc_Csk - cd05082
STKc_CDK12 - cd07864
STKc_ERK1_2_like - cd07849
STKc_TNIK - cd06637
PTKc_Srm_Brk - cd05148
STKc_ASK - cd06624
PTKc_FAK - cd05056
PTKc_InsR - cd05061
PTKc_Abl - cd05052
PTKc_Csk_like - cd05039
PTKc_Src_like - cd05034
PTKc_ALK_LTK - cd05036
PTKc_IGF-1R - cd05062
PTKc_Hck - cd05073
PTKc_Fyn_Yrk - cd05070
PTKc_Lck_Blk - cd05067
PTKc_Lyn - cd05072
PTKc_Yes - cd05069
PTKc_Src - cd05071
PTKc_Frk_like - cd05068
PTKc_InsR_like - cd05032
PTKc_DDR_like - cd05097
PTK_HER3 - cd05111
STKc_SLK_like - cd06611
STKc_SLK - cd06643
PTKc_DDR1 - cd05096
PKc_MEK2 - cd06649
PKc_MAPKK_Byr1_like - cd06620
PTKc_Ror2 - cd05091
PTKc_Musk - cd05050
PTKc_DDR - cd05051
PTKc_Trk - cd05049
PTKc_Ror - cd05048
PTK_CCK4 - cd05046
PTKc_DDR2 - cd05095
PTKc_EphR_A2 - cd05063
PTKc_TrkB - cd05093
PTKc_TrkC - cd05094
PTKc_EphR_A10 - cd05064
PTKc_TrkA - cd05092
PTKc_Ror1 - cd05090
PTKc_Btk_Bmx - cd05113
STKc_MAPK15 - cd07852
PTKc_Tec_Rlk - cd05114
PTKc_EphR_A - cd05066
PTKc_Tec_like - cd05059
PTK_Ryk - cd05043
PTKc_Jak_rpt2 - cd05038
PTKc_EphR - cd05033
PTKc_Itk - cd05112
PTKc_EphR_B - cd05065
PTKc_Tie2 - cd05088
PTKc_Jak1_rpt2 - cd05079
STKc_MST1_2 - cd06612
STKc_myosinIII_like - cd06608
STKc_MST4 - cd06640
STKc_STK25-YSK1 - cd06642
STKc_MAP4K3_like - cd06613
STKc_MST3 - cd06641
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE_like - cd07844
STKc_PFTAIRE1 - cd07869
STKc_MEKK3_like_1 - cd06653
STKc_Nek6_Nek7 - cd08224
STKc_MEKK2 - cd06652
PKc_MKK4 - cd06616
STKc_PCTAIRE3 - cd07871
STKc_CDK6 - cd07862
STKc_CDKL1_4 - cd07847
STKc_CDK10 - cd07845
STKc_PCTAIRE2 - cd07872
STKc_CDKL2_3 - cd07846
STKc_CDC2L1 - cd07843
SPS1 - COG0515
STKc_Nek7 - cd08229
STKc_Nek6 - cd08228
PK_STRAD - cd08216
STKc_PCTAIRE1 - cd07873
STKc_MST3_like - cd06609
STKc_CdkB_plant - cd07837
STKc_PRKX_like - cd05612
PKc_MAPKK - cd06605
STKc_PDK1 - cd05581
STKc_PKA - cd05580
PTKc_Tie1 - cd05089
STKc_phototropin_lik - cd05574
STKc_OSR1_SPAK - cd06610
STKc_ROCK_NDR_like - cd05573
PKc_MAPKK_plant_like - cd06623
STKc_CDKL - cd07833
PKc_MEK - cd06615
PKc_MAPKK_PBS2_like - cd06622
PKc_MKK3_6 - cd06617
PKc_MAPKK_Pek1_like - cd06621
PKc_MKK5 - cd06619
STKc_CDK4 - cd07863
STKc_Nek1 - cd08218
STKc_Nek2 - cd08217
STKc_MPK1 - cd07857
STKc_Nek - cd08215
STKc_CDK2_3 - cd07860
STKc_CDK1_euk - cd07861
STKc_Nek3 - cd08219
STKc_CNK2-like - cd08530
STKc_NLK - cd07853
STKc_Nek10 - cd08528
STKc_Nek5 - cd08225
STKc_Nek11 - cd08222
STKc_Nek4 - cd08223
STKc_Nek8 - cd08220
STKc_CDK5 - cd07839
STKc_MSK1_N - cd05613
STKc_cPKC_alpha - cd05615
STKc_CDK8_like - cd07842
STKc_GRK6 - cd05630
STKc_GRK4_like - cd05605
STKc_cPKC - cd05587
PTKc_RET - cd05045
PKc_STE - cd05122
STKc_MSK_N - cd05583
STKc_GRK4 - cd05631
STKc_cPKC_beta - cd05616
STKc_CCRK - cd07832
STKc_MAPK - cd07834
STKc_Pho85 - cd07836
STKc_CDK7 - cd07841
STKc_GRK5 - cd05632
STKc_MEKK3 - cd06651
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_CDK4_6_like - cd07838
STKc_CDK9_like - cd07840
Pkinase - pfam00069
STYKc - smart00221
TyrKc - smart00219
Pkinase_Tyr - pfam07714
STKc_MOK - cd07831
PTKc_Tyk2_rpt2 - cd05080
PTKc_Axl - cd05075
STKc_CDK1_like - cd07835
PTKc_Jak2_Jak3_rpt2 - cd05081
STKc_CMGC - cd05118
STKc_MAK_like - cd07830
STKc_CDK_like - cd07829
STKc_PKN - cd05589
PTKc_Axl_like - cd05035
PTKc_Tyro3 - cd05074
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MEKK4 - cd06626
STKc_Yank1 - cd05578
STKc_MEKK3_like - cd06625
STKc_MAPKKK_Byr2_lik - cd06628
STKc_NAK1_like - cd06917
STKc_CRIK - cd05601
STKc_Nek9 - cd08221
STKc_MAPK4_6 - cd07854
STKc_FA2-like - cd08529
STKc_nPKC_epsilon - cd05591
STKc_PKC - cd05570
STKc_nPKC_theta_delt - cd05592
STKc_MEKK1_plant - cd06632
STKc_MEKK1 - cd06630
STKc_nPKC_theta - cd05619
PTKc_Syk - cd05116
PTKc_c-ros - cd05044
PTKc_Aatyk - cd05042
PTKc_Ack_like - cd05040
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Fes_like - cd05041
PTKc_Syk_like - cd05060
PTKc_Tie - cd05047
PTK_Jak_rpt1 - cd05037
PTKc - cd00192
PTKc_Fer - cd05085
PTKc_Aatyk2 - cd05086
PTKc_Fes - cd05084
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Met_Ron - cd05058
PTK_Jak1_rpt1 - cd05077
PTKc_Zap-70 - cd05115
STKc_GRK7 - cd05607
STKc_AGC - cd05123
PKc - cd00180
STKc_YSK4 - cd06631
STKc_cGK_PKG - cd05572
STKc_GRK - cd05577
STKc_GRK1 - cd05608
STKc_MAST_like - cd05579
S_TKc - smart00220
KIND - smart00750


Swiss-Prot Protein: P06241
Identical to: NP_002028
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
SH3cd001747e-2486140
PTKc_Kitcd051042.9e-15120524
SH2cd001731.1e-40148246
PTKc_VEGFRcd050541.6e-20165527
PTKc_CSF-1Rcd051065.3e-27218525
PTKc_PDGFRcd050551.5e-20221524
PTKc_PDGFR_betacd051074.1e-10221525
PTKc_PDGFR_alphacd051054.6e-15231526
STKc_myosinIIIBcd066392.3e-05243526
STKc_TAO1cd066352.5e-05245537
PTK_Tyk2_rpt1cd050763.2e-05246521
STKc_PAK4cd066570.00077246537
STKc_PAK5cd066580.00035246532
STKc_PAK6cd066591.4e-05246536
STKc_TAO3cd066330.00079247537
STKc_PAK_IIcd066487.4e-07247524
STKc_myosinIIIAcd066389.2e-07250520
STKc_p38alpha_MAPK14cd078770.00032251533
STKc_STK10_LOKcd066441.6e-05252537
PTKc_FGFR1cd050981.1e-40253531
STKc_PAKcd066144e-15253528
STKc_p38cd078511.7e-06253533
STKc_PAK_Icd066473.9e-05254525
STKc_PAK1cd066540.00022254534
STKc_PAK2cd066559.4e-05254535
STKc_PAK3cd066567.6e-05254535
PTKc_FGFR2cd051012.7e-36255531
STKc_TAOcd066073.8e-06255537
STKc_TAO2cd066345.5e-06255537
STKc_MAP4K3cd066459.2e-07255524
STKc_MAP4K4_6cd066361.6e-05257520
PTKc_FGFRcd050532.4e-51258525
PTKc_FGFR4cd050992.7e-44258534
PTKc_FGFR3cd051002.3e-28258536
PKc_MKK7cd066185.2e-09260537
STKc_p38beta_MAPK11cd078780.00048260533
STKc_MAP4K5cd066462.3e-06261521
STKc_CDK9cd078655.5e-08262524
PTKc_EGFR_likecd050571.4e-58263535
PTKc_VEGFR3cd051021.9e-19263527
PTKc_VEGFR2cd051033.7e-16263527
STKc_Sty1_Hog1cd078562.7e-05263535
STKc_BUR1cd078662.4e-09263513
PTKc_InsR_likecd050325.4e-64264522
PTKc_Src_likecd050346.5e-228264523
PTKc_ALK_LTKcd050361.9e-66264522
PTKc_Csk_likecd050391.6e-86264523
PTKc_Ablcd050521.5e-106264524
PTKc_FAKcd050562e-75264528
PTKc_InsRcd050614.2e-48264533
PTKc_IGF-1Rcd050629.4e-49264521
PTKc_Lck_Blkcd050678.8e-170264523
PTKc_Frk_likecd050684e-161264523
PTKc_Yescd050691.5e-216264523
PTKc_Fyn_Yrkcd050701.2e-236264523
PTKc_Srccd050717.7e-211264525
PTKc_Lyncd050722e-165264523
PTKc_Hckcd050733.6e-171264523
PTKc_Cskcd050822.7e-80264523
PTKc_Chkcd050831.2e-77264523
PTKc_EGFRcd051082.4e-26264533
PTKc_HER4cd051101.8e-36264537
PTKc_HER2cd051092.4e-45264536
PTKc_Srm_Brkcd051485.7e-139264523
STKc_ASKcd066242.6e-07264525
STKc_TNIKcd066371.1e-06264520
STKc_ERK1_2_likecd078494.1e-06264536
STKc_CDK12cd078643.3e-10264535
PTK_CCK4cd050466.4e-35265522
PTKc_Rorcd050489.4e-49265523
PTKc_Trkcd050499.3e-51265529
PTKc_Muskcd050505.5e-51265522
PTKc_DDRcd050511e-40265522
PTKc_EphR_A2cd050631.6e-76265524
PTKc_EphR_A10cd050641.4e-60265524
PTKc_Ror1cd050901.9e-45265523
PTKc_Ror2cd050913.1e-39265523
PTKc_TrkAcd050926.6e-46265522
PTKc_TrkBcd050931.7e-38265533
PTKc_TrkCcd050941.2e-25265533
PTKc_DDR2cd050951.8e-44265522
PTKc_DDR1cd050961e-36265522
PTKc_DDR_likecd050974.1e-48265522
PTK_HER3cd051111.1e-37265535
STKc_SLK_likecd066114.3e-08265528
PKc_MAPKK_Byr1_likecd066201.8e-08265530
STKc_SLKcd066431e-05265537
PKc_MEK2cd066490.00021265537
PTKc_EphRcd050336.4e-94266524
PTKc_Jak_rpt2cd050383.8e-49266524
PTK_Rykcd050439.9e-24266527
PTKc_Tec_likecd050593.7e-109266521
PTKc_EphR_Bcd050652.1e-75266524
PTKc_EphR_Acd050666.1e-78266524
PTKc_Jak1_rpt2cd050792.3e-37266524
PTKc_Tie2cd050881.2e-23266537
PTKc_Itkcd051125.7e-94266521
PTKc_Tec_Rlkcd051148.5e-93266521
PTKc_Btk_Bmxcd051132.4e-94266521
STKc_MAPK15cd078525.1e-05266536
STKc_myosinIII_likecd066081.9e-09267520
STKc_MST1_2cd066128.9e-13267520
STKc_MAP4K3_likecd066139.8e-13267524
STKc_MST4cd066405.3e-08267535
STKc_MST3cd066411.6e-07267535
STKc_STK25-YSK1cd066421.7e-08267535
STKc_PCTAIRE_likecd078442.2e-07267535
STKc_PFTAIRE2cd078702.7e-06267535
PKc_MKK4cd066166.6e-08268537
STKc_MEKK2cd066527.2e-05268526
STKc_MEKK3_like_1cd066531.1e-06268525
STKc_PFTAIRE1cd078690.00015268536
STKc_Nek6_Nek7cd082245.1e-09268525
PTKc_Tie1cd050893.7e-31269530
STKc_ROCK_NDR_likecd055739.7e-05269536
STKc_phototropin_likcd055743.3e-07269528
STKc_PKAcd055803.3e-06269523
STKc_PDK1cd055814.4e-11269525
STKc_PRKX_likecd056120.00035269532
PKc_MAPKKcd066053.4e-11269521
STKc_MST3_likecd066094.2e-10269535
STKc_OSR1_SPAKcd066106.6e-13269520
PKc_MEKcd066152.7e-07269537
PKc_MKK3_6cd066171.6e-09269537
PKc_MKK5cd066190.00012269531
PKc_MAPKK_Pek1_likecd066219.2e-08269523
PKc_MAPKK_PBS2_likecd066222.2e-07269533
PKc_MAPKK_plant_likecd066232.9e-14269526
STKc_CDKLcd078331.9e-07269524
STKc_CdkB_plantcd078372.6e-08269525
STKc_CDC2L1cd078433e-08269524
STKc_CDK10cd078458.3e-08269535
STKc_CDKL2_3cd078465.7e-08269524
STKc_CDKL1_4cd078471.3e-06269524
STKc_CDK6cd078620.00027269531
STKc_PCTAIRE3cd078714.3e-06269524
STKc_PCTAIRE2cd078723.6e-05269537
STKc_PCTAIRE1cd078735.9e-05269528
PK_STRADcd082161.2e-05269526
STKc_Nek6cd082284.2e-07269525
STKc_Nek7cd082292.7e-09269525
SPS1COG05152.8e-12269536
PTKc_RETcd050452.8e-47270527
PKc_STEcd051224e-19270524
STKc_MSK_Ncd055833.5e-06270533
STKc_cPKCcd055875.8e-05270536
STKc_GRK4_likecd056055.4e-07270535
STKc_MSK1_Ncd056130.00091270533
STKc_cPKC_alphacd056157e-05270537
STKc_cPKC_betacd056160.00045270536
STKc_GRK6cd056304.2e-05270535
STKc_GRK4cd056310.00014270535
STKc_GRK5cd056321.5e-05270535
STKc_MAPKKKcd066061.1e-21270520
STKc_Cdc7_likecd066276.9e-18270520
STKc_MEKK3cd066514.1e-08270527
STKc_CCRKcd078321.7e-10270525
STKc_MAPKcd078342.6e-08270537
STKc_Pho85cd078362.2e-06270535
STKc_CDK5cd078393.9e-07270524
STKc_CDK7cd078411.2e-11270533
STKc_CDK8_likecd078422.4e-05270524
STKc_NLKcd078530.00066270531
STKc_MPK1cd078571.1e-05270528
STKc_CDK2_3cd078601e-05270532
STKc_CDK1_eukcd078617.8e-05270535
STKc_CDK4cd078630.00018270524
STKc_Nek2cd082173.5e-09270520
STKc_Nek1cd082188.3e-12270525
STKc_Nekcd082157e-16270520
STKc_Nek8cd082201.6e-06270520
STKc_Nek11cd082223.9e-09270520
STKc_Nek4cd082231.3e-09270520
STKc_Nek5cd082258.8e-17270520
STKc_Nek3cd082194.4e-12270520
STKc_Nek10cd085289e-06270522
STKc_CNK2-likecd085303e-08270521
PTKc_Axl_likecd050351.3e-46271524
PTKc_Tyro3cd050747.5e-43271524
PTKc_Axlcd050751.4e-41271524
PTKc_Tyk2_rpt2cd050801.1e-27271525
PTKc_Jak2_Jak3_rpt2cd050815.4e-40271524
STKc_CMGCcd051181.4e-12271524
STKc_PKNcd055891.8e-05271537
STKc_CDK_likecd078291.5e-13271524
STKc_MAK_likecd078301.3e-14271524
STKc_MOKcd078312e-07271524
STKc_CDK1_likecd078355.5e-06271535
STKc_CDK4_6_likecd078389.2e-06271516
STKc_CDK9_likecd078402e-13271524
STKc_Yank1cd055789.6e-09272525
STKc_MEKK4cd066261.1e-11272525
STKc_MAPKKK_Byr2_likcd066289.9e-17272520
STKc_MAPKKK_Bck1_likcd066298.8e-10272520
STKc_MEKK3_likecd066251.5e-10272525
STKc_NAK1_likecd069178.1e-09272528
STKc_CRIKcd056010.00016273537
STKc_MAPK4_6cd078542.5e-05274537
STKc_Nek9cd082211.5e-08274521
STKc_FA2-likecd085295.5e-12274520
PTKccd001923.5e-125275521
PTK_Jak_rpt1cd050372.6e-11275521
PTKc_Ack_likecd050402.9e-66275522
PTKc_Aatykcd050421.7e-16275519
PTKc_c-roscd050443.5e-65275522
PTKc_Fes_likecd050411.2e-90275522
PTKc_Tiecd050471.4e-36275525
PTKc_Met_Roncd050582.1e-56275526
PTKc_Syk_likecd050609.7e-71275525
PTK_Jak1_rpt1cd050776.2e-09275521
PTK_Jak2_Jak3_rpt1cd050784.2e-10275521
PTKc_Fescd050847.4e-69275522
PTKc_Fercd050857.9e-77275522
PTKc_Aatyk2cd050863e-18275522
PTKc_Aatyk1_Aatyk3cd050873.9e-20275522
PTKc_Sykcd051161.8e-55275525
STKc_PKCcd055701e-06275537
STKc_nPKC_epsiloncd055910.00037275536
STKc_nPKC_theta_deltcd055920.00049275537
STKc_nPKC_thetacd056194.1e-05275537
STKc_MEKK1cd066306.4e-07275525
STKc_MEKK1_plantcd066329.5e-12275520
PTKc_Zap-70cd051155.2e-56276525
PKccd001801e-68277519
STKc_AGCcd051234.8e-10277524
STKc_cGK_PKGcd055721.3e-07277523
STKc_GRKcd055779.4e-07277534
STKc_MAST_likecd055791.3e-08277525
STKc_GRK7cd056072.2e-05277534
STKc_GRK1cd056084e-05277534
STKc_YSK4cd066313.8e-09277520
SH3_1pfam000182.4e-2488135
SH2pfam000174.1e-44149231
Pkinasepfam000696.6e-46271520
SH3smart003266.1e-2583141
SH3_2pfam076535.5e-1186140
SH2smart002523.4e-34147237
Pkinase_Tyrpfam077142.9e-152271520
STYKcsmart002211.5e-56271504
TyrKcsmart002191e-131271520
S_TKcsmart002203e-54281524
KINDsmart007500.0007348530

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041706Polymorphismp.ASP506GLUN/A
Swiss-ProtVAR_041705Polymorphismp.GLY410ARGN/A
Swiss-ProtVAR_014661Polymorphismp.ILE445PHEN/A
Swiss-ProtVAR_041704Polymorphismp.VAL243LEUN/A



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