Results for the protein: P25098

Results for the Protein: P25098

126302521

156

ADRBK1

NCBI, UniProt

ARBK1_HUMAN RecName: Full=Beta-adrenergic receptor kinase 1; Short=Beta-ARK-1; AltName: Full=G-protein coupled receptor kinase 2

			0 2 0 0 2

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Swiss-Prot Protein: P25098

Identical to: NP_001610

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	1.1e-13	150	527
STKc_ROCK1	cd05622	2.8e-15	150	514
STKc_PAK3	cd06656	2.8e-07	151	488
STKc_PAK5	cd06658	2e-06	166	467
STKc_PAK6	cd06659	3.3e-08	166	481
STKc_PAK1	cd06654	9.4e-07	168	481
STKc_PAK4	cd06657	2.5e-06	168	481
STKc_JNK2	cd07876	0.00018	168	527
STKc_myosinIIIB	cd06639	2.6e-08	171	454
STKc_PAK_I	cd06647	5.4e-06	172	479
STKc_PAK2	cd06655	2.7e-07	172	482
PTKc_EGFR_like	cd05057	0.00079	174	440
STKc_PAK	cd06614	3.2e-15	175	466
STKc_myosinIIIA	cd06638	6.4e-08	175	448
STKc_JNK3	cd07874	0.00045	175	566
STKc_p38alpha_MAPK14	cd07877	0.00018	175	530
STKc_JNK	cd07850	0.00015	176	525
STKc_p38	cd07851	4.1e-07	177	468
STKc_p38beta_MAPK11	cd07878	3e-05	177	530
STKc_CDK9	cd07865	1.4e-07	178	453
STKc_p38gamma_MAPK12	cd07880	5.4e-06	178	521
STKc_MAP4K4_6	cd06636	0.00037	179	453
STKc_PAK_II	cd06648	4e-10	179	471
STKc_MAPK15	cd07852	2.1e-06	180	471
STKc_Sty1_Hog1	cd07856	3e-06	180	500
PKc_MKK7	cd06618	4.5e-10	181	473
STKc_MAP4K3	cd06645	9e-09	181	433
STKc_MAP4K5	cd06646	2.2e-08	181	433
PTKc_EGFR	cd05108	0.001	182	472
STKc_ASK	cd06624	3.8e-15	182	453
PTKc_Ror2	cd05091	0.00032	183	440
STKc_STK10_LOK	cd06644	1.8e-07	183	477
PTKc_ALK_LTK	cd05036	1.4e-05	184	430
PTKc_Abl	cd05052	0.00094	184	452
PTKc_FAK	cd05056	0.00012	184	452
PTKc_InsR	cd05061	0.00024	184	458
PTKc_IGF-1R	cd05062	0.00029	184	449
PTKc_Frk_like	cd05068	5e-05	184	463
STKc_TEY_MAPK_plant	cd07858	8.9e-08	184	538
PTKc_Ror	cd05048	6.7e-06	185	424
PTKc_Ror1	cd05090	0.00016	185	440
PTKc_TrkA	cd05092	0.00027	185	454
PTKc_TrkB	cd05093	0.00024	185	457
PKc_MAPKK_Byr1_like	cd06620	3.9e-07	185	467
PKc_MEK2	cd06649	2.2e-06	185	543
PKc_MEK1	cd06650	5.8e-05	185	542
STKc_PCTAIRE_like	cd07844	2.3e-11	185	488
STKc_CDK12	cd07864	2.8e-08	185	453
PTKc_Src_like	cd05034	0.00047	186	428
PTKc_InsR_like	cd05032	5.1e-05	186	430
PTKc_Chk	cd05083	5.5e-05	186	449
PTKc_Itk	cd05112	0.00063	186	425
PTKc_Btk_Bmx	cd05113	0.0006	186	448
PKc_MKK4	cd06616	6.8e-08	186	471
STKc_MAP4K3_like	cd06613	6.6e-12	187	452
STKc_CDK10	cd07845	4e-10	187	467
STKc_BUR1	cd07866	2.5e-07	187	453
STKc_PFTAIRE1	cd07869	3.7e-05	187	500
STKc_PFTAIRE2	cd07870	1.1e-07	187	488
STKc_PCTAIRE3	cd07871	4.2e-06	187	453
STKc_PCTAIRE2	cd07872	1.7e-06	187	465
STKc_PCTAIRE1	cd07873	2.8e-05	187	465
PTKc_Jak_rpt2	cd05038	3.8e-05	188	437
STKc_SLK_like	cd06611	6.2e-09	188	465
STKc_TNIK	cd06637	4.2e-06	188	453
STKc_SLK	cd06643	1.2e-06	188	462
STKc_CDC2L6	cd07867	2.4e-06	188	488
STKc_CDK8	cd07868	4.2e-05	188	488
STKc_Nek6_Nek7	cd08224	6.8e-14	188	449
STKc_Nek6	cd08228	1.6e-10	188	449
STKc_Nek7	cd08229	1.1e-11	188	449
PTKc_Srm_Brk	cd05148	0.00023	189	463
STKc_ROCK_NDR_like	cd05573	3.5e-27	189	507
STKc_phototropin_lik	cd05574	5.6e-36	189	479
STKc_PKA	cd05580	3.5e-66	189	491
STKc_PDK1	cd05581	1.6e-48	189	453
STKc_DMPK_like	cd05597	2.1e-38	189	514
STKc_LATS	cd05598	7.8e-17	189	530
STKc_NDR_like	cd05599	2.2e-18	189	510
STKc_CRIK	cd05601	8.9e-17	189	510
STKc_MAST	cd05609	1.3e-31	189	484
STKc_PRKX_like	cd05612	3.4e-53	189	492
STKc_MRCK_alpha	cd05623	3e-17	189	513
STKc_MRCK_beta	cd05624	1.7e-22	189	512
STKc_LATS1	cd05625	2.6e-14	189	537
STKc_LATS2	cd05626	2.9e-12	189	530
STKc_NDR2	cd05627	1.8e-15	189	551
STKc_NDR1	cd05628	6.9e-14	189	537
STKc_NDR_like_fungal	cd05629	8.8e-26	189	537
STKc_Sid2p_Dbf2p	cd05600	2.5e-15	189	549
PKc_MAPKK	cd06605	1.2e-11	189	457
STKc_myosinIII_like	cd06608	1.5e-08	189	402
STKc_MST3_like	cd06609	5e-11	189	470
STKc_MST1_2	cd06612	8.8e-11	189	453
PKc_MEK	cd06615	8.8e-08	189	471
PKc_MKK5	cd06619	3.3e-05	189	467
PKc_MAPKK_Pek1_like	cd06621	1.3e-07	189	458
PKc_MKK3_6	cd06617	3.9e-09	189	468
PKc_MAPKK_PBS2_like	cd06622	1.2e-07	189	496
STKc_MEKK3_like	cd06625	2.3e-14	189	453
STKc_MST4	cd06640	4.6e-08	189	467
STKc_MST3	cd06641	6.9e-08	189	459
STKc_STK25-YSK1	cd06642	1.3e-08	189	478
PKc_MAPKK_plant_like	cd06623	1.5e-16	189	446
STKc_MEKK2	cd06652	2.3e-06	189	454
STKc_MEKK3_like_1	cd06653	3.2e-09	189	447
STKc_OSR1_SPAK	cd06610	1.7e-11	189	453
STKc_CDKL	cd07833	7e-07	189	453
STKc_CdkB_plant	cd07837	7e-13	189	454
STKc_CDKL2_3	cd07846	1.1e-05	189	453
STKc_CDKL1_4	cd07847	1e-07	189	488
STKc_CDKL5	cd07848	0.00022	189	453
STKc_ERK1_2_like	cd07849	4.2e-06	189	527
STKc_CDK6	cd07862	0.0001	189	461
SPS1	COG0515	7.6e-52	189	614
PKc_STE	cd05122	6.4e-20	190	452
STKc_Yank1	cd05578	4.2e-79	190	453
STKc_cPKC	cd05587	2.6e-62	190	513
STKc_MSK_N	cd05583	3.6e-79	190	472
STKc_GRK4_like	cd05605	5.6e-97	190	474
STKc_MSK1_N	cd05613	2.9e-59	190	472
STKc_MSK2_N	cd05614	1.6e-66	190	514
STKc_cPKC_alpha	cd05615	2.9e-40	190	530
STKc_cPKC_beta	cd05616	1.7e-44	190	521
STKc_GRK6	cd05630	2.5e-93	190	474
STKc_GRK5	cd05632	7.9e-87	190	474
STKc_GRK4	cd05631	1.9e-86	190	474
STKc_MAPKKK	cd06606	5e-28	190	453
STKc_Cdc7_like	cd06627	7.8e-17	190	440
STKc_MAPKKK_Byr2_lik	cd06628	5.4e-20	190	453
STKc_MEKK3	cd06651	7.4e-09	190	455
STKc_YSK4	cd06631	1e-08	190	453
STKc_CCRK	cd07832	4.2e-13	190	454
STKc_MAPK	cd07834	1.1e-08	190	465
STKc_CDK5	cd07839	4e-07	190	453
STKc_Pho85	cd07836	9.8e-08	190	488
STKc_CDK7	cd07841	1.1e-10	190	461
STKc_CDK8_like	cd07842	5.3e-07	190	453
STKc_NLK	cd07853	7.8e-06	190	567
STKc_MPK1	cd07857	1.3e-06	190	477
STKc_TDY_MAPK_plant	cd07859	9.8e-07	190	534
STKc_CDK2_3	cd07860	2.8e-06	190	453
STKc_CDK1_euk	cd07861	2.3e-06	190	488
STKc_CDK4	cd07863	1.1e-05	190	453
STKc_Nek2	cd08217	2.1e-10	190	447
STKc_Nek1	cd08218	2.3e-12	190	453
STKc_Nek3	cd08219	2.1e-15	190	445
STKc_Nek8	cd08220	6e-10	190	448
STKc_Nek11	cd08222	1.1e-07	190	453
STKc_Nek4	cd08223	2.6e-07	190	453
STKc_Nek5	cd08225	2.7e-14	190	453
STKc_Nek	cd08215	9.3e-19	190	453
STKc_Nek10	cd08528	1.3e-08	190	448
STKc_FA2-like	cd08529	1.2e-12	190	440
STKc_CNK2-like	cd08530	2.7e-12	190	445
PTKc_Tyk2_rpt2	cd05080	7.9e-05	191	449
STKc_CMGC	cd05118	5.7e-13	191	453
STKc_PKN	cd05589	7.1e-56	191	512
STKc_MAPKKK_Bck1_lik	cd06629	1.7e-09	191	418
STKc_MAK_like	cd07830	2.4e-11	191	453
STKc_CDK_like	cd07829	9.8e-15	191	453
STKc_CDK1_like	cd07835	1.8e-07	191	482
STKc_CDK4_6_like	cd07838	3.8e-08	191	453
STKc_CDK9_like	cd07840	4.7e-12	191	453
STKc_ERK5	cd07855	7.8e-07	191	502
STKc_NAK1_like	cd06917	2.3e-11	192	467
STKc_CDC2L1	cd07843	8.4e-07	192	453
STKc_RSK_N	cd05582	2.8e-72	194	512
STKc_p70S6K	cd05584	7.5e-62	194	514
STKc_MEKK4	cd06626	7.2e-09	194	453
STKc_MOK	cd07831	1.5e-12	194	453
PTKc	cd00192	2.7e-09	195	452
PTKc_Fes_like	cd05041	6.7e-06	195	426
PTKc_c-ros	cd05044	3.5e-05	195	449
PTKc_Met_Ron	cd05058	3.2e-05	195	450
PTKc_Syk_like	cd05060	0.00037	195	434
PTKc_Jak2_Jak3_rpt2	cd05081	1.6e-05	195	448
PTKc_Fes	cd05084	1.4e-05	195	449
PTKc_Syk	cd05116	1.7e-05	195	454
STKc_PKC	cd05570	7.3e-50	195	512
STKc_PKB	cd05571	3.8e-63	195	529
STKc_SGK	cd05575	5.8e-60	195	512
STKc_aPKC	cd05588	6e-49	195	530
STKc_nPKC_eta	cd05590	1.6e-51	195	513
STKc_nPKC_epsilon	cd05591	5e-47	195	513
STKc_nPKC_theta_delt	cd05592	2.6e-57	195	514
STKc_PKB_gamma	cd05593	1.8e-43	195	517
STKc_PKB_alpha	cd05594	4.9e-48	195	527
STKc_PKB_beta	cd05595	2.8e-52	195	514
STKc_SGK1	cd05602	1.1e-48	195	533
STKc_SGK2	cd05603	2.4e-47	195	523
STKc_SGK3	cd05604	3.9e-49	195	531
STKc_aPKC_zeta	cd05617	2.4e-36	195	530
STKc_aPKC_iota	cd05618	2e-36	195	523
STKc_nPKC_theta	cd05619	4.4e-45	195	514
STKc_nPKC_delta	cd05620	1.6e-38	195	514
STKc_MEKK1	cd06630	1.7e-11	195	454
STKc_MEKK1_plant	cd06632	1.1e-13	195	453
STKc_Nek9	cd08221	2e-09	195	453
STKc_beta_ARK	cd05606	3.7e-236	196	473
STKc_GRK3	cd05633	1.8e-248	196	474
PKc	cd00180	2.3e-63	197	451
PTKc_Zap-70	cd05115	0.0002	197	452
STKc_AGC	cd05123	2e-128	197	453
STKc_cGK_PKG	cd05572	6.3e-47	197	460
STKc_GRK	cd05577	4.7e-226	197	473
STKc_MAST_like	cd05579	1.8e-31	197	458
STKc_YPK1_like	cd05585	3.6e-71	197	526
STKc_Sck1_like	cd05586	7.3e-65	197	566
STKc_GRK7	cd05607	1.9e-70	197	473
STKc_GRK1	cd05608	4.3e-82	197	473
STKc_Rim15_like	cd05611	1e-14	197	459
PH_GRK2_subgroup	cd01240	2.8e-81	557	669
PH	cd00821	6.1e-13	561	650
PH-like	cd00900	4e-10	561	650
RGS	pfam00615	5.5e-27	54	174
Pkinase	pfam00069	9e-100	191	453
PH	pfam00169	3.3e-16	559	652
RGS	smart00315	1.2e-30	54	174
Pkinase_Tyr	pfam07714	1.6e-12	191	440
TyrKc	smart00219	4.5e-11	191	440
STYKc	smart00221	1e-69	191	453
S_TKc	smart00220	3.1e-84	201	453
S_TK_X	smart00133	4.1e-12	454	533
PH	smart00233	2.7e-12	559	652

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040379	Polymorphism	p.ARG578GLN	N/A
Swiss-Prot	VAR_040378	Polymorphism	p.ILE184THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258