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Results for the Protein: P08922
126302596

ROS1_HUMAN RecName: Full=Proto-oncogene tyrosine-protein kinase ROS; AltName: Full=Proto-oncogene c-Ros; AltName: Full=Proto-oncogene c-Ros-1; AltName: Full=Receptor tyrosine kinase c-ros oncogene 1; AltName: Full=c-Ros receptor tyrosine kinase; Flags: Precursor
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Default View:

FN3 - smart00060
FN3 - cd00063
fn3 - pfam00041
PTKc_CSF-1R - cd05106
PTKc_PDGFR_alpha - cd05105
PTKc_PDGFR_beta - cd05107
PTKc_Kit - cd05104
STKc_TAO1 - cd06635
STKc_PAK5 - cd06658
PTKc_FGFR1 - cd05098
STKc_myosinIIIB - cd06639
PTKc_PDGFR - cd05055
STKc_PAK4 - cd06657
STKc_PAK - cd06614
STKc_p38 - cd07851
PTKc_FGFR2 - cd05101
PKc_MKK7 - cd06618
PTKc_FGFR - cd05053
STKc_myosinIIIA - cd06638
PTKc_FGFR4 - cd05099
STKc_PAK1 - cd06654
STKc_PAK_I - cd06647
STKc_PAK6 - cd06659
STKc_TAO2 - cd06634
STKc_TAO - cd06607
STKc_PAK_II - cd06648
STKc_PAK2 - cd06655
STKc_PAK3 - cd06656
STKc_CDK10 - cd07845
STKc_CDK9 - cd07865
STKc_STK10_LOK - cd06644
STKc_MAP4K5 - cd06646
PTK_Tyk2_rpt1 - cd05076
SPS1 - COG0515
STKc_ASK - cd06624
PTKc_HER4 - cd05110
STKc_Nek6 - cd08228
PTKc_Tie2 - cd05088
PTKc_FGFR3 - cd05100
PTKc_EGFR - cd05108
PTKc_HER2 - cd05109
PTKc_EGFR_like - cd05057
STKc_Nek7 - cd08229
PTKc_ALK_LTK - cd05036
PTKc_TrkC - cd05094
PTKc_DDR2 - cd05095
PTKc_TrkA - cd05092
PTKc_Ror1 - cd05090
PTKc_DDR1 - cd05096
PTKc_TrkB - cd05093
PTKc_Csk - cd05082
PTK_HER3 - cd05111
STKc_SLK - cd06643
PTKc_Yes - cd05069
PTKc_VEGFR2 - cd05103
PTKc_VEGFR3 - cd05102
PTKc_DDR_like - cd05097
PTKc_FAK - cd05056
PTKc_Abl - cd05052
PTKc_Ror - cd05048
PTKc_VEGFR - cd05054
PTKc_DDR - cd05051
PTKc_Musk - cd05050
PTK_Ryk - cd05043
PTK_CCK4 - cd05046
PTKc_Lyn - cd05072
PTKc_InsR - cd05061
PTKc_IGF-1R - cd05062
PTKc_Fyn_Yrk - cd05070
PTKc_Src - cd05071
PTKc_Hck - cd05073
PTKc_Trk - cd05049
PTKc_Csk_like - cd05039
PTKc_EphR_A2 - cd05063
PTKc_Lck_Blk - cd05067
PTKc_EphR_A10 - cd05064
PTKc_Frk_like - cd05068
PKc_MKK4 - cd06616
STKc_PCTAIRE_like - cd07844
PTKc_Itk - cd05112
PTKc_EphR_A - cd05066
PTKc_InsR_like - cd05032
PTKc_EphR - cd05033
PTKc_Jak_rpt2 - cd05038
PTKc_Btk_Bmx - cd05113
PTKc_EphR_B - cd05065
PTKc_Chk - cd05083
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Tyk2_rpt2 - cd05080
STKc_MAP4K3 - cd06645
STKc_STK25-YSK1 - cd06642
STKc_TNIK - cd06637
PTKc_Srm_Brk - cd05148
STKc_SLK_like - cd06611
STKc_myosinIII_like - cd06608
PTKc_Tec_Rlk - cd05114
STKc_MST3 - cd06641
STKc_MST1_2 - cd06612
PTKc_Src_like - cd05034
STKc_MST4 - cd06640
STKc_MAP4K3_like - cd06613
STKc_MEKK3_like_1 - cd06653
STKc_Nek6_Nek7 - cd08224
STKc_CDKL1_4 - cd07847
STKc_CDKL2_3 - cd07846
STKc_CDK7 - cd07841
STKc_MAPK15 - cd07852
STKc_CDK9_like - cd07840
STKc_CDK12 - cd07864
STKc_CdkB_plant - cd07837
STKc_Nek4 - cd08223
STKc_CDK6 - cd07862
STKc_MAPK4_6 - cd07854
STKc_CRIK - cd05601
PTKc_Ror2 - cd05091
STKc_ROCK_NDR_like - cd05573
PTKc_Jak1_rpt2 - cd05079
PTKc_Tec_like - cd05059
STKc_PKA - cd05580
PKc_MKK3_6 - cd06617
STKc_MST3_like - cd06609
PTKc_Tie1 - cd05089
PKc_MAPKK_PBS2_like - cd06622
PKc_MAPKK_plant_like - cd06623
STKc_OSR1_SPAK - cd06610
PKc_MAPKK - cd06605
PKc_MAPKK_Pek1_like - cd06621
PKc_MKK5 - cd06619
PKc_MEK - cd06615
STKc_Nek11 - cd08222
STKc_Nek8 - cd08220
STKc_Nek3 - cd08219
STKc_Nek10 - cd08528
STKc_Nek1 - cd08218
STKc_CNK2-like - cd08530
STKc_FA2-like - cd08529
STKc_Nek - cd08215
STKc_Nek5 - cd08225
STKc_cPKC_alpha - cd05615
STKc_Cdc7_like - cd06627
STKc_cPKC - cd05587
PTKc_RET - cd05045
STKc_CDK4 - cd07863
STKc_Yank1 - cd05578
PKc_STE - cd05122
STKc_MAPKKK_Byr2_lik - cd06628
STKc_CCRK - cd07832
STKc_Pho85 - cd07836
STKc_MAPK - cd07834
STKc_NAK1_like - cd06917
STKc_MAPKKK - cd06606
STKc_YSK4 - cd06631
STKc_MEKK3 - cd06651
STYKc - smart00221
Pkinase_Tyr - pfam07714
PTKc_Axl - cd05075
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
TyrKc - smart00219
STKc_PKN - cd05589
STKc_CDK1_like - cd07835
Pkinase - pfam00069
STKc_GRK5 - cd05632
PK_STRAD - cd08216
STKc_GRK4 - cd05631
STKc_GRK4_like - cd05605
PKc_MAPKK_Byr1_like - cd06620
STKc_MOK - cd07831
STKc_p70S6K - cd05584
STKc_RSK_N - cd05582
STKc_MEKK4 - cd06626
PTKc_c-ros - cd05044
PTKc_Met_Ron - cd05058
PTKc_Fes_like - cd05041
PTKc_Zap-70 - cd05115
STKc_nPKC_theta_delt - cd05592
STKc_Nek2 - cd08217
PTKc - cd00192
PTKc_Ack_like - cd05040
STKc_beta_ARK - cd05606
STKc_nPKC_theta - cd05619
PTKc_Tie - cd05047
PTKc_Fer - cd05085
STKc_nPKC_epsilon - cd05591
STKc_PDK1 - cd05581
STKc_MEKK1_plant - cd06632
STKc_PKB - cd05571
STKc_CDK4_6_like - cd07838
STKc_CDK_like - cd07829
STKc_MEKK3_like - cd06625
STKc_Nek9 - cd08221
STKc_MEKK1 - cd06630
STKc_MAPKKK_Bck1_lik - cd06629
STKc_GRK7 - cd05607
STKc_MAK_like - cd07830
STKc_BUR1 - cd07866
STKc_MAST_like - cd05579
PTKc_Syk - cd05116
PTK_Jak1_rpt1 - cd05077
PTK_Jak2_Jak3_rpt1 - cd05078
PTKc_Fes - cd05084
PTKc_Syk_like - cd05060
PTK_Jak_rpt1 - cd05037
PKc - cd00180
PTKc_Aatyk - cd05042
STKc_YPK1_like - cd05585
PTKc_Aatyk2 - cd05086
STKc_AGC - cd05123
PTKc_Aatyk1_Aatyk3 - cd05087
STKc_GRK - cd05577
STKc_CMGC - cd05118
STKc_cGK_PKG - cd05572
S_TKc - smart00220
STKc_CDC2L1 - cd07843
STKc_PKC - cd05570


Swiss-Prot Protein: P08922
Identical to: NP_002935
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
FN3cd000636.2e-0999188
FN3cd000631.5e-16194281
FN3cd000633.8e-10558668
FN3cd000635.9e-0610411147
FN3cd000631.7e-0916561748
PTKc_CSF-1Rcd051062.4e-4119042220
PTKc_PDGFR_alphacd051052.7e-2619072221
PTKc_PDGFR_betacd051073.3e-2119072220
PTKc_Kitcd051045.2e-3319162217
STKc_TAO1cd066350.0003319202244
STKc_PAK5cd066586.8e-0519202222
PTKc_FGFR1cd050981.3e-6019222226
STKc_myosinIIIBcd066390.0002119222218
PTKc_PDGFRcd050554e-3719232215
STKc_PAK4cd066570.0001619242236
STKc_PAKcd066141.2e-1119252236
STKc_p38cd078510.0001719252263
PTKc_FGFR2cd051012.8e-6219262226
PKc_MKK7cd066182e-0619272241
PTKc_FGFRcd050535.5e-8219282220
PTKc_FGFR4cd050994.2e-6719282233
STKc_myosinIIIAcd066389.9e-0519282217
STKc_PAK_Icd066474e-0619302238
STKc_PAK1cd066543.2e-0619302236
STKc_PAK6cd066592.2e-0619302236
STKc_TAO2cd066341e-0519302255
STKc_TAOcd066074.2e-0519312244
STKc_PAK_IIcd066483.5e-0719312222
STKc_PAK2cd066559.4e-0619312241
STKc_PAK3cd066562.2e-0619312238
STKc_CDK10cd078453.1e-0619322260
STKc_STK10_LOKcd066443.7e-0519332245
STKc_CDK9cd078650.0004319332208
PTK_Tyk2_rpt1cd050761.5e-0619352216
STKc_MAP4K5cd066464.6e-0619352216
SPS1COG05151.7e-2119352327
STKc_ASKcd066241.6e-0719362217
PTKc_EGFR_likecd050571.6e-6119372224
PTKc_Tie2cd050888.7e-4119372237
PTKc_FGFR3cd051001.2e-5519372263
PTKc_HER2cd051091.6e-4819372228
PTKc_HER4cd051104.1e-3819372247
PTKc_EGFRcd051087.6e-4319372260
STKc_Nek6cd082282.2e-0719372217
STKc_Nek7cd082292e-0819372220
PTKc_ALK_LTKcd050363.8e-12919382217
PTKc_Csk_likecd050392.1e-5519392218
PTK_Rykcd050433.2e-3819392222
PTK_CCK4cd050466.3e-6619392217
PTKc_Muskcd050501.3e-8319392217
PTKc_DDRcd050511.3e-6919392217
PTKc_Ablcd050528e-7319392219
PTKc_Rorcd050484.6e-6919392218
PTKc_VEGFRcd050547.2e-3719392221
PTKc_InsRcd050613.8e-9319392226
PTKc_IGF-1Rcd050622.1e-9219392217
PTKc_EphR_A2cd050639.1e-5719392219
PTKc_EphR_A10cd050643.6e-4819392219
PTKc_Lck_Blkcd050671.7e-6519392218
PTKc_Frk_likecd050683e-8619392218
PTKc_FAKcd050569.4e-8319392223
PTKc_Trkcd050491.9e-8819392217
PTKc_Fyn_Yrkcd050706e-6719392218
PTKc_Srccd050712.9e-6519392220
PTKc_Hckcd050731.3e-6319392218
PTKc_Lyncd050726.8e-6419392218
PTKc_Cskcd050828.9e-5619392218
PTKc_Ror1cd050903.3e-5519392218
PTKc_TrkBcd050936.5e-6419392224
PTKc_TrkAcd050921.7e-7019392217
PTKc_TrkCcd050943.4e-4419392224
PTKc_DDR2cd050951.7e-6119392217
PTKc_DDR1cd050963.1e-5319392217
PTKc_DDR_likecd050971.5e-6619392217
PTKc_VEGFR3cd051024.1e-3919392221
PTKc_VEGFR2cd051037.4e-3719392221
PTKc_Yescd050691.7e-6619392218
PTK_HER3cd051111.9e-3819392228
STKc_SLKcd066435.3e-0619392235
PTKc_Jak_rpt2cd050383.4e-5719402219
PTKc_EphRcd050334.5e-7719402219
PTKc_InsR_likecd050322.8e-11719402217
PTKc_EphR_Acd050661.7e-6219402219
PTKc_EphR_Bcd050651.3e-6019402219
PTKc_Tyk2_rpt2cd050801.1e-3019402220
PTKc_Jak2_Jak3_rpt2cd050815e-3819402219
PTKc_Chkcd050831.9e-6119402218
PTKc_Btk_Bmxcd051133.7e-6819402216
PTKc_Itkcd051121.3e-6419402216
PKc_MKK4cd066162.1e-0619402240
STKc_PCTAIRE_likecd078440.0004819402243
PTKc_Src_likecd050344.7e-8419412218
PTKc_Tec_Rlkcd051143.6e-6419412216
PTKc_Srm_Brkcd051481.2e-6219412218
STKc_myosinIII_likecd066081.4e-0719412223
STKc_SLK_likecd066116.6e-0719412229
STKc_MST1_2cd066128.6e-0919412208
STKc_MAP4K3_likecd066133e-1019412215
STKc_MST4cd066401.4e-0619412231
STKc_MST3cd066415.3e-0719412231
STKc_STK25-YSK1cd066421.1e-0719412233
STKc_MAP4K3cd066451.8e-0519412215
STKc_TNIKcd066370.0002319412223
STKc_MEKK3_like_1cd066531.3e-0519422223
STKc_Nek6_Nek7cd082241.6e-0719422220
PTKc_Tec_likecd050593e-6619432216
PTKc_Jak1_rpt2cd050791.5e-3819432219
PTKc_Tie1cd050891.2e-4619432247
PTKc_Ror2cd050912.9e-4719432218
STKc_ROCK_NDR_likecd055738e-0619432244
STKc_PKAcd055801.2e-0619432238
STKc_CRIKcd056011.1e-0519432258
STKc_MST3_likecd066092.2e-0819432222
STKc_OSR1_SPAKcd066101.3e-1019432223
PKc_MEKcd066151.9e-0619432243
PKc_MKK5cd066196.8e-0519432236
PKc_MAPKK_Pek1_likecd066212.2e-0619432227
PKc_MAPKK_PBS2_likecd066225.7e-0619432246
PKc_MAPKK_plant_likecd066231.4e-1019432223
PKc_MAPKKcd066056.2e-0819432220
PKc_MKK3_6cd066173.8e-0519432232
STKc_CdkB_plantcd078370.000219432223
STKc_CDK7cd078413.2e-0819432216
STKc_CDK9_likecd078401.3e-0619432208
STKc_CDKL1_4cd078473.1e-0519432244
STKc_CDKL2_3cd078464e-0519432222
STKc_MAPK15cd078520.0006819432230
STKc_MAPK4_6cd078540.0008619432266
STKc_CDK6cd078620.0001519432243
STKc_CDK12cd078642.3e-0619432239
STKc_Nek4cd082237.5e-1019432217
PTKc_RETcd050452.6e-8019442220
PKc_STEcd051222.7e-1319442211
STKc_Yank1cd055782.5e-0719442223
STKc_cPKCcd055870.0003119442273
STKc_cPKC_alphacd056150.0003619442276
STKc_Cdc7_likecd066271.6e-1419442208
STKc_MAPKKK_Byr2_likcd066281.1e-1419442217
STKc_YSK4cd066311.7e-0919442223
STKc_MEKK3cd066515.1e-0519442217
STKc_MAPKKKcd066066e-1819442223
STKc_NAK1_likecd069176.7e-1119442216
STKc_CCRKcd078326e-0619442223
STKc_Pho85cd078360.0002819442244
STKc_MAPKcd078343.8e-0619442265
STKc_CDK4cd078632e-0519442244
STKc_Nek1cd082187.3e-0619442217
STKc_Nek3cd082194.2e-1019442217
STKc_Nek8cd082207.3e-0619442217
STKc_Nek11cd082222e-0919442217
STKc_Nek5cd082253e-0619442217
STKc_Nekcd082152.4e-1319442217
STKc_FA2-likecd085293.5e-0819442223
STKc_CNK2-likecd085301.3e-0719442217
STKc_Nek10cd085283.6e-0719442213
PTKc_Axl_likecd050354.8e-8119452219
PTKc_Tyro3cd050741.9e-7219452219
PTKc_Axlcd050754.8e-6219452219
STKc_PKNcd055891e-0519452275
STKc_CDK1_likecd078350.0003819452262
STKc_GRK4_likecd056051.3e-0519462247
STKc_GRK4cd056310.0004819462247
STKc_GRK5cd056320.0002119462247
PK_STRADcd082160.0001619462217
PKc_MAPKK_Byr1_likecd066207.9e-0619472227
STKc_MOKcd078311.7e-0619472218
STKc_RSK_Ncd055826.7e-0619482275
STKc_p70S6Kcd055841.6e-0519482277
STKc_MEKK4cd066263.4e-0719482209
PTKccd001921e-13919492216
PTKc_Ack_likecd050401.9e-6219492217
PTKc_Fes_likecd050418.7e-8119492217
PTKc_c-roscd050441e-23719492217
PTKc_Met_Roncd050585.1e-7819492221
PTKc_Zap-70cd051152e-5219492220
STKc_nPKC_theta_deltcd055923.8e-0519492277
STKc_Nek2cd082171.7e-1119492217
PTKc_Tiecd050471.4e-4919502220
PTKc_Fercd050857.4e-7319502217
STKc_PDK1cd055811.4e-1019502221
STKc_nPKC_epsiloncd055910.000219502273
STKc_beta_ARKcd056060.0003619502238
STKc_nPKC_thetacd056195.9e-0619502277
STKc_PKBcd055713.4e-0519502280
STKc_MEKK3_likecd066252.4e-1019502223
STKc_MAPKKK_Bck1_likcd066291.7e-0919502209
STKc_MEKK1cd066306.1e-1019502219
STKc_MEKK1_plantcd066325.1e-1119502211
STKc_CDK_likecd078291.6e-0919502208
STKc_CDK4_6_likecd078388.2e-0719502208
STKc_Nek9cd082211.8e-0719502217
PKccd001806.4e-6219512215
PTKc_Aatykcd050421.1e-3419512217
PTK_Jak_rpt1cd050373.1e-1219512216
PTKc_Syk_likecd050601.9e-6519512220
PTK_Jak1_rpt1cd050771.6e-0919512216
PTK_Jak2_Jak3_rpt1cd050783e-1219512216
PTKc_Fescd050849.6e-7219512217
PTKc_Aatyk2cd050861.9e-3119512217
PTKc_Aatyk1_Aatyk3cd050871.5e-4219512217
STKc_CMGCcd051182.1e-0919512208
PTKc_Sykcd051167.4e-5519512223
STKc_AGCcd051233e-0919512221
STKc_cGK_PKGcd055725.3e-0819512215
STKc_GRKcd055770.0003719512225
STKc_YPK1_likecd055850.0001519512274
STKc_MAST_likecd055795.6e-0619512228
STKc_GRK7cd056070.0001419512246
STKc_MAK_likecd078302e-1019512208
STKc_BUR1cd078660.0007419512208
STKc_CDC2L1cd078430.0004119572208
STKc_PKCcd055705.1e-0619662275
fn3pfam000410.0001100183
fn3pfam000411e-08196275
Pkinasepfam000699.7e-3619452217
FN3smart000604.8e-0799177
FN3smart000603.7e-12195272
FN3smart000600.0003810441137
FN3smart000609.1e-0516591738
Pkinase_Tyrpfam077145e-15519452215
TyrKcsmart002192.5e-14519452215
STYKcsmart002213.6e-4919452188
S_TKcsmart002209.5e-4419552218

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs2243380 Polymorphismp.ARG167GLNN/A
dbSNPrs35841892 Polymorphismp.ARG1506GLYN/A
Swiss-ProtVAR_030654Polymorphismp.ARG2039HISN/A
dbSNPrs210968 Polymorphismp.ASN2240LYSN/A
Swiss-ProtVAR_041442Polymorphismp.ASN13SERN/A
dbSNPrs34582164 Polymorphismp.ASN790SERN/A
Swiss-ProtVAR_041458Polymorphismp.ASP2203ASNN/A
Swiss-ProtVAR_030655Polymorphismp.ASP2213ASNN/A
Swiss-ProtVAR_041459Polymorphismp.ASP2213GLUN/A
dbSNPrs12664076 Polymorphismp.ASP1776HISN/A
dbSNPrs529038 Polymorphismp.ASP2213HISN/A
Swiss-ProtVAR_041453Polymorphismp.CYS1370ARGN/A
Swiss-ProtVAR_041450Polymorphismp.GLN865HISN/A
Swiss-ProtVAR_030653Polymorphismp.GLU1902LYSN/A
Swiss-ProtVAR_041443Polymorphismp.GLY126VALN/A
Swiss-ProtVAR_041455Polymorphismp.HIS1999ASNN/A
dbSNPrs28639589 Polymorphismp.ILE537METN/A
Swiss-ProtVAR_041456Polymorphismp.LYS2003ARGN/A
Swiss-ProtVAR_049713Polymorphismp.LYS2328ARGN/A
dbSNPrs529156 Polymorphismp.LYS2228GLNN/A
dbSNPrs17079086 Polymorphismp.PHE1439SERN/A
Swiss-ProtVAR_041457Polymorphismp.PHE2138SERN/A
Swiss-ProtVAR_041444Polymorphismp.PRO224SERN/A
dbSNPrs619203 Polymorphismp.SER2229CYSN/A
dbSNPrs2229079 Polymorphismp.SER1109LEUN/A
Swiss-ProtVAR_041449Polymorphismp.SER653PHEN/A
Swiss-ProtVAR_041446Polymorphismp.SER370PRON/A
dbSNPrs1998206 Polymorphismp.THR145PRON/A
Swiss-ProtVAR_041445Polymorphismp.TYR338CYSN/A
Swiss-ProtVAR_041447Polymorphismp.TYR419HISN/A
Swiss-ProtVAR_041451Polymorphismp.TYR1239PHEN/A
Swiss-ProtVAR_041452Polymorphismp.TYR1353SERN/A



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