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Results for the Protein: P09619
129890

PGFRB_HUMAN RecName: Full=Platelet-derived growth factor receptor beta; Short=PDGF-R-beta; Short=PDGFR-beta; AltName: Full=Beta platelet-derived growth factor receptor; AltName: Full=Beta-type platelet-derived growth factor receptor; AltName: Full=CD140 antigen-like family member B; AltName: Full=Platelet-derived growth factor receptor 1; Short=PDGFR-1; AltName: CD_antigen=CD140b; Flags: Precursor

Known Diseases associated with this Protein:
  BASAL GANGLIA CALCIFICATION, IDIOPATHIC, 4
  BASAL GANGLIA CALCIFICATION, IDIOPATHIC, 4 (IBGC4)
  MYOFIBROMATOSIS, INFANTILE 1 (IMF1)
  MYOFIBROMATOSIS, INFANTILE, 1
8
9
4
2
11
Tips:
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Default View:

ig - pfam00047
Ig1_NCAM-2 - cd05866
I-set - pfam07679
IG - smart00409
IG_like - smart00410
IGc2 - smart00408
Ig1_VEGFR_like - cd05742
Ig1_PDGFR-alphabeta - cd05861
Ig - cd00096
Ig4_SCFR - cd05860
Ig4_SCFR_like - cd04975
Ig4_PDGFR-alpha - cd05859
PTKc_CSF-1R - cd05106
PTKc_PDGFR_beta - cd05107
PTKc_Kit - cd05104
PTKc_PDGFR - cd05055
PTKc_PDGFR_alpha - cd05105
STKc_PAK - cd06614
PTKc_FGFR1 - cd05098
PTKc_FGFR2 - cd05101
PTKc_FGFR4 - cd05099
PTKc_FGFR - cd05053
PTKc_FGFR3 - cd05100
PTKc_EGFR_like - cd05057
PTKc_VEGFR2 - cd05103
PTKc_VEGFR3 - cd05102
PTKc_VEGFR - cd05054
PTKc_Hck - cd05073
PTKc_Lyn - cd05072
PTKc_Srm_Brk - cd05148
PTKc_Lck_Blk - cd05067
PTKc_Tie1 - cd05089
PTKc_Csk - cd05082
PTKc_Src_like - cd05034
PTKc_Csk_like - cd05039
PTKc_InsR_like - cd05032
PTKc_Src - cd05071
PTKc_FAK - cd05056
PTKc_Abl - cd05052
PTKc_ALK_LTK - cd05036
PTKc_Fyn_Yrk - cd05070
PTKc_Frk_like - cd05068
PTKc_Yes - cd05069
PTKc_IGF-1R - cd05062
PTKc_InsR - cd05061
PTKc_DDR1 - cd05096
PTKc_DDR_like - cd05097
PTKc_TrkB - cd05093
PTKc_DDR2 - cd05095
PTKc_Ror1 - cd05090
PTKc_Trk - cd05049
PTKc_Ror - cd05048
PTK_CCK4 - cd05046
PTKc_Musk - cd05050
PTKc_DDR - cd05051
PTKc_TrkA - cd05092
PTKc_Ror2 - cd05091
PTKc_EphR_A2 - cd05063
PTKc_TrkC - cd05094
PTKc_EphR - cd05033
PTKc_Tie2 - cd05088
PTKc_Btk_Bmx - cd05113
PTKc_EphR_A - cd05066
PTKc_Tec_like - cd05059
PTKc_Tec_Rlk - cd05114
PTKc_Jak_rpt2 - cd05038
STKc_MAP4K3_like - cd06613
STKc_myosinIII_like - cd06608
PKc_MAPKK_plant_like - cd06623
STKc_PKA - cd05580
STKc_PDK1 - cd05581
PKc_MKK3_6 - cd06617
PKc_MAPKK - cd06605
SPS1 - COG0515
STKc_MAPKKK - cd06606
PTKc_RET - cd05045
STKc_Nek - cd08215
STKc_CDK7 - cd07841
STKc_Cdc7_like - cd06627
STYKc - smart00221
TyrKc - smart00219
PTKc_Axl - cd05075
Pkinase_Tyr - pfam07714
Pkinase - pfam00069
STKc_CDK_like - cd07829
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
STKc_Nek2 - cd08217
PTKc_Aatyk - cd05042
PTKc_c-ros - cd05044
PTKc_Fes_like - cd05041
PTKc_Ack_like - cd05040
PTKc - cd00192
PTKc_Tie - cd05047
PTKc_Syk_like - cd05060
STKc_CMGC - cd05118
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Aatyk2 - cd05086
PKc - cd00180
STKc_AGC - cd05123
S_TKc - smart00220
PTK_Ryk - cd05043
STKc_Nek7 - cd08229
PTK_Jak_rpt1 - cd05037
PTKc_Met_Ron - cd05058
PTK_Jak1_rpt1 - cd05077
PTKc_HER2 - cd05109
PTKc_EGFR - cd05108
PTKc_HER4 - cd05110
STKc_Nek3 - cd08219
STKc_MAPKKK_Byr2_lik - cd06628
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_EphR_B - cd05065
PTKc_Jak1_rpt2 - cd05079
PTK_HER3 - cd05111
PTKc_EphR_A10 - cd05064
PTKc_Itk - cd05112
PTKc_Fes - cd05084
STKc_STK25-YSK1 - cd06642
STKc_YSK4 - cd06631
PTKc_Chk - cd05083
STKc_SLK - cd06643
STKc_MAPKKK_Bck1_lik - cd06629
PTKc_Tyk2_rpt2 - cd05080
STKc_CNK2-like - cd08530
PTKc_Zap-70 - cd05115
PTKc_Fer - cd05085
STKc_MEKK3_like - cd06625
PTKc_Syk - cd05116
PTK_Jak2_Jak3_rpt1 - cd05078
STKc_MST3_like - cd06609
PKc_MKK7 - cd06618
STKc_MEKK1_plant - cd06632
STKc_CDK12 - cd07864
STKc_OSR1_SPAK - cd06610
STKc_FA2-like - cd08529
STKc_NAK1_like - cd06917
PKc_STE - cd05122
STKc_CDK9_like - cd07840
STKc_MST1_2 - cd06612
STKc_SLK_like - cd06611
STKc_PKC - cd05570


Swiss-Prot Protein: P09619
Identical to: NP_002600
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Ig1_NCAM-2cd058660.00077209315
Ig1_VEGFR_likecd057421.2e-42228309
Ig1_PDGFR-alphabetacd058616.1e-61228312
Igcd000963.9e-07231307
Ig4_SCFR_likecd049754.6e-54314415
Ig4_PDGFR-alphacd058594.5e-69314415
Ig4_SCFRcd058606.6e-09314415
Igcd000964.8e-05334410
PTKc_CSF-1Rcd051065.8e-164559963
PTKc_PDGFRcd050551.8e-276562962
PTKc_PDGFR_betacd05107562963
PTKc_Kitcd051041.7e-163562962
PTKc_PDGFR_alphacd051053e-228562964
STKc_PAKcd066142.3e-05581969
PTKc_FGFR1cd050989e-86582969
PTKc_FGFR2cd051018.6e-80584969
PTKc_FGFR4cd050998.5e-82587980
PTKc_FGFR3cd051002.3e-735871003
PTKc_FGFRcd050538.4e-112587963
PTKc_VEGFRcd050542e-136592965
PTKc_EGFR_likecd050574.3e-32592974
PTKc_VEGFR3cd051021.9e-121592965
PTKc_VEGFR2cd051038.3e-117592965
PTKc_InsR_likecd050323.3e-45593960
PTKc_Src_likecd050341.2e-51593961
PTKc_Csk_likecd050392.5e-31593961
PTKc_ALK_LTKcd050362e-35593960
PTKc_Ablcd050521.8e-43593962
PTKc_FAKcd050564.1e-36593966
PTKc_InsRcd050619.5e-29593971
PTKc_IGF-1Rcd050622.4e-30593960
PTKc_Frk_likecd050683.8e-50593961
PTKc_Yescd050691.6e-24593961
PTKc_Fyn_Yrkcd050701.2e-25593961
PTKc_Srccd050712.7e-26593963
PTKc_Lyncd050722.1e-37593961
PTKc_Hckcd050731.4e-35593961
PTKc_Cskcd050823.2e-30593961
PTKc_Tie1cd050899.4e-45593983
PTKc_Lck_Blkcd050671.5e-34593961
PTKc_Srm_Brkcd051482e-33593961
PTK_CCK4cd050469.2e-18594960
PTKc_Rorcd050481.9e-26594961
PTKc_Trkcd050493.6e-34594960
PTKc_Muskcd050508.4e-48594960
PTKc_DDRcd050511.4e-27594960
PTKc_EphR_A2cd050636.2e-20594962
PTKc_Ror1cd050902.8e-18594961
PTKc_Ror2cd050915.4e-15594961
PTKc_TrkAcd050924.2e-32594960
PTKc_TrkCcd050943.4e-12594971
PTKc_DDR2cd050957.7e-29594960
PTKc_DDR1cd050967.6e-31594960
PTKc_DDR_likecd050976.7e-29594960
PTKc_TrkBcd050931.7e-24594974
PTKc_EphRcd050334.1e-20595962
PTKc_Jak_rpt2cd050382.8e-26595962
PTKc_Tec_likecd050593.2e-27595959
PTKc_EphR_Acd050663.3e-20595962
PTKc_Tie2cd050886.4e-42595984
PTKc_Btk_Bmxcd051134.5e-38595959
PTKc_Tec_Rlkcd051143.1e-31595959
STKc_myosinIII_likecd066088.9e-06596958
STKc_MAP4K3_likecd066133.7e-05596961
STKc_PKAcd055800.00036598767
STKc_PDK1cd055811.4e-07598978
PKc_MKK3_6cd066177e-05598957
PKc_MAPKKcd066050.00019598972
PKc_MAPKK_plant_likecd066233.6e-07598968
SPS1COG05151.8e-085981100
PTKc_RETcd050451.1e-72599965
STKc_MAPKKKcd066062.5e-14599962
STKc_Cdc7_likecd066271.1e-09599955
STKc_CDK7cd078410.00053599955
STKc_Nekcd082151.2e-08599961
PTKc_Axl_likecd050352.7e-34600962
PTKc_Tyro3cd050742.2e-32600962
PTKc_Axlcd050751.1e-31600962
STKc_CDK_likecd078291.5e-05600952
PTKccd001924.2e-135604959
PTKc_Ack_likecd050402.8e-20604960
PTKc_Fes_likecd050413.6e-33604960
PTKc_Aatykcd050424e-10604960
PTKc_c-roscd050442.6e-33604960
PTKc_Tiecd050471.6e-51604963
PTKc_Syk_likecd050605.7e-20604963
PTKc_Aatyk2cd050866.1e-05604960
PTKc_Aatyk1_Aatyk3cd050873.9e-07604960
STKc_CMGCcd051185.1e-05604962
STKc_Nek2cd082178.3e-05604962
PKccd001806.8e-34606958
STKc_AGCcd051238.3e-06606951
PTK_Rykcd050431.4e-20677961
STKc_Nek7cd082290.00015689963
PTK_Jak_rpt1cd050370.00022691959
PTKc_Met_Roncd050584.3e-38691964
PTK_Jak1_rpt1cd050770.00026691959
PTKc_EGFRcd051082.9e-126931010
PTKc_HER2cd051091.2e-12693972
PTKc_HER4cd051102.9e-106931003
PTKc_Jak2_Jak3_rpt2cd050818.8e-13694962
STKc_MAPKKK_Byr2_likcd066285.6e-07694962
STKc_Nek3cd082190.00088694962
PTKc_EphR_Bcd050659.9e-18697962
PTKc_Jak1_rpt2cd050792.6e-14697962
PTK_HER3cd051111.3e-12698974
PTKc_EphR_A10cd050641.6e-09701962
PTKc_Itkcd051121.7e-32703959
PTKc_Fescd050845.3e-29705960
STKc_STK25-YSK1cd066420.00099711984
STKc_YSK4cd066317.4e-07718962
PTKc_Chkcd050839.8e-35724961
STKc_SLKcd066430.00095724967
STKc_MAPKKK_Bck1_likcd066298.1e-05726952
PTKc_Tyk2_rpt2cd050802.3e-09729963
PTKc_Zap-70cd051155.4e-20730963
STKc_CNK2-likecd085300.0005730958
PTKc_Fercd050857.4e-38731960
STKc_MEKK3_likecd066250.00029732960
PTKc_Sykcd051162.6e-25734963
PTK_Jak2_Jak3_rpt1cd050782.5e-05735959
STKc_MST3_likecd066090.00036738971
PKc_MKK7cd066187.4e-05739976
STKc_MEKK1_plantcd066326.1e-05740955
STKc_CDK12cd078640.001745983
STKc_OSR1_SPAKcd066103.9e-05746956
STKc_FA2-likecd085290.00022750961
STKc_NAK1_likecd069174.9e-05755962
PKc_STEcd051223.2e-08762954
STKc_CDK9_likecd078400.00045763971
STKc_MST1_2cd066122.6e-05771952
STKc_SLK_likecd066110.00023772976
STKc_PKCcd055700.00015787998
igpfam000472.1e-0747102
igpfam000475.7e-07228293
Pkinasepfam000691.6e-16600958
I-setpfam076790.00055214310
IGsmart004091.9e-14220311
IG_likesmart004101.9e-14220311
IGc2smart004086e-12227298
Pkinase_Tyrpfam077142.8e-185600958
STYKcsmart002219.2e-39600931
TyrKcsmart002197.6e-122600958
S_TKcsmart002204.9e-19610962

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_069925Diseasep.ARG561CYSMyofibromatosis, infantile 1 (IMF1)
Swiss-ProtVAR_069321Diseasep.ARG987TRPBasal ganglia calcification, idiopathic, 4 (IBGC4)
Swiss-ProtVAR_042030Polymorphismp.ASN718TYRN/A
Swiss-ProtVAR_042027Polymorphismp.GLU282LYSN/A
Swiss-ProtVAR_042028Polymorphismp.GLU485LYSN/A
dbSNPrs17110944 Polymorphismp.ILE29PHEN/A
Swiss-ProtVAR_069320Diseasep.LEU658PROBasal ganglia calcification, idiopathic, 4 (IBGC4)
Swiss-ProtVAR_049717Polymorphismp.PRO345SERN/A
Swiss-ProtVAR_069926Diseasep.PRO660THRMyofibromatosis, infantile 1 (IMF1)
Swiss-ProtVAR_035125Polymorphismp.SER180PHEN/A
Swiss-ProtVAR_042031Polymorphismp.THR882ILEN/A
dbSNPrs74943037 Polymorphismp.THR464METN/A
Swiss-ProtVAR_042029Polymorphismp.TYR589HISN/A
OMIM173410.0003 Diseasep.ARG561CYSMYOFIBROMATOSIS, INFANTILE, 1
OMIM173410.0002 Diseasep.ARG987TRPBASAL GANGLIA CALCIFICATION, IDIOPATHIC, 4
OMIM173410.0001 Diseasep.LEU658PROBASAL GANGLIA CALCIFICATION, IDIOPATHIC, 4
OMIM173410.0004 Diseasep.PRO660THRMYOFIBROMATOSIS, INFANTILE, 1



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