Results for the protein: P09874

Results for the Protein: P09874

130781

142

PARP1

NCBI, UniProt

PARP1_HUMAN RecName: Full=Poly [ADP-ribose] polymerase 1; Short=PARP-1; AltName: Full=ADP-ribosyltransferase diphtheria toxin-like 1; Short=ARTD1; AltName: Full=NAD(+) ADP-ribosyltransferase 1; Short=ADPRT 1; AltName: Full=Poly[ADP-ribose] synthase 1

			0 8 0 3 5

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Default View: PADR1 - pfam08063 BRCT - smart00292 WGR - smart00773 WGR - pfam05406	Swiss-Prot Protein: P09874 Identical to: NP_001609 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
BRCT	smart00292	1.9e-08	388	466
WGR	smart00773	7.6e-35	548	633
WGR	pfam05406	2.2e-30	549	632

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1805409	Polymorphism	p.ALA188THR	N/A
Swiss-Prot	VAR_035852	Polymorphism	p.GLU488VAL	N/A
dbSNP	rs3219145	Polymorphism	p.LYS940ARG	N/A
Swiss-Prot	VAR_050460	Polymorphism	p.PHE54LEU	N/A
Swiss-Prot	VAR_050461	Polymorphism	p.PRO377SER	N/A
Swiss-Prot	VAR_019172	Polymorphism	p.SER383TYR	N/A
dbSNP	rs1136410	Polymorphism	p.VAL762ALA	N/A
Swiss-Prot	VAR_019171	Polymorphism	p.VAL334ILE	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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