Results for the protein: P15153

Results for the Protein: P15153

131806

5880

RAC2

NCBI, UniProt

RAC2_HUMAN RecName: Full=Ras-related C3 botulinum toxin substrate 2; AltName: Full=GX; AltName: Full=Small G protein; AltName: Full=p21-Rac2; Flags: Precursor

Known Diseases associated with this Protein:
NEUTROPHIL IMMUNODEFICIENCY SYNDROME
NEUTROPHIL IMMUNODEFICIENCY SYNDROME (NEUID)

2

1

1

0

2

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Swiss-Prot Protein: P15153

Identical to: NP_002863

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
RhoG	cd01875	4.3e-122	1	192
Rab30	cd04114	8.9e-07	1	176
Rnd3_RhoE_Rho8	cd04172	7.2e-50	1	179
Rnd1_Rho6	cd04174	1.1e-31	1	192
COG1100	COG1100	5.1e-43	1	191
Rab8_Rab10_Rab13_lik	cd01867	7.5e-13	2	179
Rab1_Ypt1	cd01869	3.4e-13	2	179
RhoBTB	cd01873	9.1e-31	2	176
Rab35	cd04110	6.8e-07	2	189
Rab33B_Rab33A	cd04115	1.7e-08	2	185
Rab9	cd04116	4e-09	2	176
Rab14	cd04122	8e-10	2	179
Rit_Rin_Ric	cd04141	1.9e-13	2	185
M_R_Ras_like	cd04145	1.6e-23	2	177
Rab5_related	cd01860	2e-12	3	177
Rab3	cd01865	5e-09	3	180
Rac1_like	cd01871	2.8e-133	3	176
Cdc42	cd01874	1.7e-111	3	177
Rho2	cd04129	1e-63	3	192
Rnd	cd04131	4.8e-56	3	179
Rop_like	cd04133	2.7e-92	3	180
Rap_like	cd04136	3.8e-17	3	177
H_N_K_Ras_like	cd04138	3.8e-22	3	177
Rnd2_Rho7	cd04173	4.4e-23	3	192
Rap1	cd04175	3.6e-16	3	178
Rap2	cd04176	5.1e-18	3	177
Rab	cd00154	1.6e-40	4	174
Rho	cd00157	3.5e-128	4	175
Ran	cd00877	1.1e-10	4	154
Rab6	cd01861	9.2e-11	4	176
Rab7	cd01862	1.3e-12	4	182
Rab18	cd01863	7.3e-12	4	176
Miro1	cd01893	7.6e-11	4	179
RabL4	cd04101	1.8e-07	4	177
Rab23_like	cd04106	1.7e-14	4	154
Rab32_Rab38	cd04107	2.3e-07	4	191
Rab36_Rab34	cd04108	0.00011	4	191
Rab28	cd04109	0.00055	4	192
Rab26	cd04112	8.2e-06	4	189
Rab4	cd04113	3e-11	4	176
Rab15	cd04117	3.5e-10	4	176
Rab24	cd04118	2.9e-07	4	190
RJL	cd04119	3.6e-06	4	178
Rab21	cd04123	2.7e-13	4	177
RabL2	cd04124	6.8e-07	4	166
	cd04125	7e-06	4	192
Rab20	cd04126	0.00014	4	189
Rab27A	cd04127	3.2e-08	4	180
Spg1	cd04128	8.5e-05	4	149
Tc10	cd04135	8.7e-107	4	177
Rho4_like	cd04132	4.1e-86	4	192
RalA_RalB	cd04139	4.8e-11	4	179
RRP22	cd04142	0.00021	4	192
Wrch_1	cd04130	1.1e-92	4	176
Ras	cd00876	3.1e-32	5	176
Rab19	cd01864	5.9e-06	5	176
Rab11_like	cd01868	2e-09	5	177
RhoA_like	cd01870	1.3e-82	5	177
Rho3	cd04134	6.3e-64	5	192
RheB	cd04137	1.1e-10	5	192
ARHI_like	cd04140	1.4e-06	5	177
Ras2	cd04144	1.4e-06	5	192
RERG_RasL11_like	cd04146	2.7e-10	5	178
Ras_dva	cd04147	1.1e-05	5	192
RSR1	cd04177	2.3e-05	5	192
Rab39	cd04111	2.7e-07	7	190
Ras_like_GTPase	cd00882	1.8e-52	8	174
Ras	pfam00071	3e-86	5	178
RAS	smart00173	1.1e-18	4	179
RAB	smart00175	7.9e-19	4	179
Miro	pfam08477	1.7e-13	5	118
small_GTPase	smart00010	8.1e-52	6	157
RHO	smart00174	5.1e-135	6	179
RAN	smart00176	0.00014	9	186

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_017452	Disease	p.ASP57ASN	Neutrophil immunodeficiency syndrome (NEUID)
Swiss-Prot	VAR_036569	Polymorphism	p.PRO29LEU	N/A
OMIM	602049.0001	Disease	p.ASP57ASN	NEUTROPHIL IMMUNODEFICIENCY SYNDROME

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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