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Results for the Protein: P01112
131869

RASH_HUMAN RecName: Full=GTPase HRas; AltName: Full=H-Ras-1; AltName: Full=Ha-Ras; AltName: Full=Transforming protein p21; AltName: Full=c-H-ras; AltName: Full=p21ras; Contains: RecName: Full=GTPase HRas, N-terminally processed; Flags: Precursor

Known Diseases associated with this Protein:
  BLADDER CANCER, SOMATIC
  CONGENITAL MYOPATHY WITH EXCESS OF MUSCLE SPINDLES (CMEMS)
  COSTELLO SYNDROME
  COSTELLO SYNDROME, INCLUDED;;
  COSTELLO SYNDROME, SEVERE
  EPIDERMAL NEVUS WITH UROTHELIAL CAN
  EPIDERMAL NEVUS, SOMATIC
  EPIDERMAL NEVUS, SOMATIC, INCLUDED
  FACIOCUTANEOSKELETAL SYNDROME (FCSS)
  MYOPATHY, CONGENITAL, WITH EXCESS OF MUSCLE SPINDLES
  MYOPATHY, CONGENITAL, WITH EXCESS OF MUSCLE SPINDLES, INCLUDED;;
  NEVUS SEBACEOUS, SOMATIC
  NEVUS SEBACEOUS, SOMATIC, INCLUDED
  NEVUS SEBACEOUS, SOMATIC, INCLUDED;;
  SCHIMMELPENNING-FEUERSTEIN-MIMS SYNDROME (SFM)
  SCHIMMELPENNING-FEUERSTEIN-MIMS SYNDROME, SOMATIC MOSAIC, INCLUDED;;
  SPERMATOCYTIC SEMINOMA, SOMATIC, INCLUDED
  THYROID CARCINOMA, FOLLICULAR, SOMATIC
30
2
15
0
17
Tips:
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Default View:

small_GTPase - smart00010
Rab2 - cd01866
COG1100 - COG1100
Rnd3_RhoE_Rho8 - cd04172
RhoG - cd01875
Rab30 - cd04114
M_R_Ras_like - cd04145
Rit_Rin_Ric - cd04141
RhoBTB - cd01873
Rab8_Rab10_Rab13_lik - cd01867
H_N_K_Ras_like - cd04138
RheB - cd04137
ARHI_like - cd04140
RSR1 - cd04177
Rap_like - cd04136
Rap2 - cd04176
Rap1 - cd04175
RhoA_like - cd01870
Rab3 - cd01865
Rop_like - cd04133
Rab5_related - cd01860
Rac1_like - cd01871
Rnd - cd04131
Cdc42 - cd01874
Rho2 - cd04129
RabL2 - cd04124
- cd04125
Rab21 - cd04123
Rab24 - cd04118
Rab15 - cd04117
Wrch_1 - cd04130
Rab12 - cd04120
Rab14 - cd04122
Rhes_like - cd04143
RAS - smart00173
RAB - smart00175
Rab9 - cd04116
RGK - cd04148
RJL - cd04119
Tc10 - cd04135
RalA_RalB - cd04139
RRP22 - cd04142
Rho4_like - cd04132
Rab28 - cd04109
Rab7 - cd01862
Rab19 - cd01864
Rab11_like - cd01868
Rab6 - cd01861
Rab33B_Rab33A - cd04115
Ran - cd00877
Rho - cd00157
Rab - cd00154
Rab1_Ypt1 - cd01869
Rab18 - cd01863
Rab39 - cd04111
Rab26 - cd04112
Rab4 - cd04113
Rab35 - cd04110
Rab36_Rab34 - cd04108
RabL4 - cd04101
Centaurin_gamma - cd04103
Rab23_like - cd04106
Rab32_Rab38 - cd04107
Ras - pfam00071
Miro - pfam08477
Ras_dva - cd04147
Ras - cd00876
Rab27A - cd04127
Miro1 - cd01893
Arf_Arl - cd00878
RERG_RasL11_like - cd04146
Rho3 - cd04134
Ras2 - cd04144
RHO - smart00174
Era_like - cd00880
Ras_like_GTPase - cd00882
RAN - smart00176


Swiss-Prot Protein: P01112
Identical to: NP_005334, NP_001123914
   Default View:















































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Rab2cd018661.5e-301166
RhoGcd018752.6e-191189
Rab30cd041141.4e-181164
Rnd3_RhoE_Rho8cd041720.000971164
COG1100COG11004e-361184
Rab8_Rab10_Rab13_likcd018672.9e-362166
RhoBTBcd018730.000142163
Rit_Rin_Riccd041411.7e-712172
M_R_Ras_likecd041451.2e-842164
Rab5_relatedcd018603.7e-213164
Rab3cd018651.1e-203166
RhoA_likecd018702.6e-223164
Rac1_likecd018715.4e-203163
Cdc42cd018747.5e-153163
Rho2cd041294.3e-143187
Rndcd041310.000143166
Rop_likecd041338.5e-103167
Rap_likecd041364.5e-913164
RheBcd041377.2e-453182
H_N_K_Ras_likecd041386.8e-1143164
ARHI_likecd041401.9e-363164
Rap1cd041753.6e-753165
Rap2cd041761.3e-683164
RSR1cd041772.2e-543189
Rabcd001541.3e-494161
Rhocd001572.7e-284162
Rancd008777.6e-144171
Rab6cd018617.3e-224163
Rab7cd018629.3e-184169
Rab19cd018642.3e-114163
Rab11_likecd018684e-244164
Rab1_Ypt1cd018691.6e-344166
Rab18cd018631.8e-274163
RabL4cd041018.1e-144164
Centaurin_gammacd041031.1e-054163
Rab23_likecd041069.5e-204163
Rab32_Rab38cd041077.3e-134184
Rab36_Rab34cd041081.8e-054186
Rab28cd041093e-094189
Rab35cd041102.6e-204188
Rab39cd041112.5e-104186
Rab26cd041121.7e-104186
Rab4cd041133.1e-154163
Rab33B_Rab33Acd041152.8e-204165
Rab9cd041169.1e-224163
Rab15cd041172.5e-194163
Rab24cd041186.9e-084186
Rab12cd041202.9e-054187
Rab14cd041227.3e-244166
Rab21cd041231e-254164
RabL2cd041241.8e-064167
cd041253.2e-124185
Wrch_1cd041301.4e-124163
Rho4_likecd041324e-144189
Tc10cd041353.3e-134160
RalA_RalBcd041392.6e-1114166
RRP22cd041421.9e-064189
Rhes_likecd041434.9e-134189
RJLcd041192.4e-114165
RGKcd041484e-094188
Rascd008761.3e-1005163
Arf_Arlcd008781e-055162
Miro1cd018939.5e-065158
Rab27Acd041273.3e-205167
Rho3cd041349.6e-095184
Ras2cd041442.8e-685189
RERG_RasL11_likecd041466.4e-325165
Ras_dvacd041472e-145189
Era_likecd008804.1e-058163
Ras_like_GTPasecd008824.1e-588161
Raspfam000713.3e-955165
small_GTPasesmart000104.4e-551167
RASsmart001736.8e-1214166
RABsmart001752.1e-384166
Miropfam084775.4e-195119
RHOsmart001741.1e-126166
RANsmart001760.000229189

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_045982Diseasep.ALA146THRFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_045983Diseasep.ALA146VALFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_006838Polymorphismp.GLN61LEUN/A
Swiss-ProtVAR_045977Diseasep.GLN22LYSCongenital myopathy with excess of muscle spindles (CMEMS)
Swiss-ProtVAR_045979Polymorphismp.GLN61LYSN/A
Swiss-ProtVAR_045980Diseasep.GLU63LYSCongenital myopathy with excess of muscle spindles (CMEMS)
Swiss-ProtVAR_026106Diseasep.GLY12ALAFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_068817Diseasep.GLY13ARGSchimmelpenning-Feuerstein-Mims syndrome (SFM)
Swiss-ProtVAR_068816Diseasep.GLY12ASPFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_026108Diseasep.GLY13ASPFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_045975Diseasep.GLY12CYSFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_026107Diseasep.GLY13CYSFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_045976Diseasep.GLY12GLUFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_006837Diseasep.GLY12SERFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_006836Diseasep.GLY12VALFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_045981Diseasep.LYS117ARGFaciocutaneoskeletal syndrome (FCSS)
Swiss-ProtVAR_045978Diseasep.THR58ILEFaciocutaneoskeletal syndrome (FCSS)
OMIM190020.0008 Diseasep.ALA146THRCOSTELLO SYNDROME
OMIM190020.0012 Diseasep.ALA146VALCOSTELLO SYNDROME
OMIM190020.0010 Diseasep.GLN22LYSMYOPATHY, CONGENITAL, WITH EXCESS OF MUSCLE SPINDLES
OMIM190020.0002 Diseasep.GLN61LYSTHYROID CARCINOMA, FOLLICULAR, SOMATIC||SPERMATOCYTIC SEMINOMA, SOMATIC, INCLUDED
OMIM190020.0009 Diseasep.GLU63LYSMYOPATHY, CONGENITAL, WITH EXCESS OF MUSCLE SPINDLES
OMIM190020.0004 Diseasep.GLY12ALACOSTELLO SYNDROME
OMIM190020.0017 Diseasep.GLY13ARGNEVUS SEBACEOUS, SOMATIC||SCHIMMELPENNING-FEUERSTEIN-MIMS SYNDROME, SOMATIC MOSAIC, INCLUDED;;||EPIDERMAL NEVUS, SOMATIC
OMIM190020.0013 Diseasep.GLY12ASPCOSTELLO SYNDROME, SEVERE||NEVUS SEBACEOUS, SOMATIC, INCLUDED
OMIM190020.0005 Diseasep.GLY13ASPCOSTELLO SYNDROME
OMIM190020.0014 Diseasep.GLY12CYSCOSTELLO SYNDROME||NEVUS SEBACEOUS, SOMATIC, INCLUDED;;||EPIDERMAL NEVUS, SOMATIC, INCLUDED
OMIM190020.0007 Diseasep.GLY13CYSCOSTELLO SYNDROME
OMIM190020.0003 Diseasep.GLY12SERCOSTELLO SYNDROME||MYOPATHY, CONGENITAL, WITH EXCESS OF MUSCLE SPINDLES, INCLUDED;;||EPIDERMAL NEVUS WITH UROTHELIAL CAN
OMIM190020.0001 Diseasep.GLY12VALBLADDER CANCER, SOMATIC||COSTELLO SYNDROME, INCLUDED;;||MYOPATHY, CONGENITAL, WITH EXCESS OF MUSCLE SPINDLES, INCLUDED;;
OMIM190020.0006 Diseasep.LYS117ARGCOSTELLO SYNDROME
OMIM190020.0011 Diseasep.THR58ILECOSTELLO SYNDROME



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