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Results for the Protein: P01111
131883

RASN_HUMAN RecName: Full=GTPase NRas; AltName: Full=Transforming protein N-Ras; Flags: Precursor

Known Diseases associated with this Protein:
  AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME 4 (ALPS4)
  AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IV
  EPIDERMAL NEVUS, SOMATIC
  EPIDERMAL NEVUS, SOMATIC, INCLUDED
  JUVENILE MYELOMONOCYTIC LEUKEMIA, INCLUDED;;
  NOONAN SYNDROME 6
  NOONAN SYNDROME 6 (NS6)
  NOONAN SYNDROME 6, INCLU
  RECTAL CANCER, SOMATIC
  THYROID CARCINOMA, FOLLICULAR, SOMATIC
10
4
7
0
7
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

small_GTPase - smart00010
Rab2 - cd01866
COG1100 - COG1100
Rab30 - cd04114
RhoG - cd01875
Rit_Rin_Ric - cd04141
M_R_Ras_like - cd04145
RhoBTB - cd01873
Rab8_Rab10_Rab13_lik - cd01867
Rap1 - cd04175
ARHI_like - cd04140
Rap2 - cd04176
Rnd - cd04131
H_N_K_Ras_like - cd04138
Rho2 - cd04129
RSR1 - cd04177
RhoA_like - cd01870
Rab3 - cd01865
RheB - cd04137
Rab5_related - cd01860
Rac1_like - cd01871
Rap_like - cd04136
Cdc42 - cd01874
Rop_like - cd04133
RalA_RalB - cd04139
RRP22 - cd04142
Tc10 - cd04135
Rab24 - cd04118
Rab15 - cd04117
RGK - cd04148
RJL - cd04119
Rab12 - cd04120
- cd04125
RAS - smart00173
RAB - smart00175
Rab9 - cd04116
Rho4_like - cd04132
Wrch_1 - cd04130
Rab21 - cd04123
Rab14 - cd04122
RabL2 - cd04124
Rhes_like - cd04143
Rab28 - cd04109
Rab7 - cd01862
Rab18 - cd01863
Rab19 - cd01864
Rab6 - cd01861
Rab33B_Rab33A - cd04115
Ran - cd00877
Rho - cd00157
Rab - cd00154
Rab11_like - cd01868
Rab1_Ypt1 - cd01869
Rab39 - cd04111
Rab26 - cd04112
Rab4 - cd04113
Rab35 - cd04110
Rab36_Rab34 - cd04108
RabL4 - cd04101
Centaurin_gamma - cd04103
Rab23_like - cd04106
Rab32_Rab38 - cd04107
Ras - pfam00071
Miro - pfam08477
Rab27A - cd04127
Arf_Arl - cd00878
Rho3 - cd04134
Miro1 - cd01893
Ras - cd00876
Ras_dva - cd04147
Ras2 - cd04144
RERG_RasL11_like - cd04146
RHO - smart00174
Era_like - cd00880
Ras_like_GTPase - cd00882
RAN - smart00176


Swiss-Prot Protein: P01111
Identical to: NP_002515
   Default View:














































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Rab2cd018668.6e-301166
RhoGcd018755.5e-181184
Rab30cd041142.5e-171164
COG1100COG11001.1e-381183
Rab8_Rab10_Rab13_likcd018672e-352166
RhoBTBcd018730.000112163
Rit_Rin_Riccd041415.3e-722172
M_R_Ras_likecd041454.7e-822164
Rab5_relatedcd018602.6e-203164
Rab3cd018654.4e-203166
RhoA_likecd018702.8e-203164
Rac1_likecd018713.1e-183163
Cdc42cd018743.3e-123163
Rop_likecd041332.6e-093167
Rap_likecd041363.4e-903164
RheBcd041372.9e-493189
H_N_K_Ras_likecd041383.9e-1133164
ARHI_likecd041401.7e-353164
Rap1cd041755e-753165
Rap2cd041766.4e-683164
RSR1cd041779.9e-563189
Rho2cd041293.2e-123189
Rndcd041317.4e-053165
Rabcd001541.4e-484161
Rhocd001576.8e-294162
Rancd008776.2e-134171
Rab6cd018611.5e-214163
Rab7cd018624.2e-174169
Rab18cd018632.9e-284163
Rab19cd018642e-104163
Rab11_likecd018681.7e-234164
Rab1_Ypt1cd018695e-344166
RabL4cd041011.9e-094164
Centaurin_gammacd041034e-054163
Rab23_likecd041062.5e-214163
Rab32_Rab38cd041071.7e-124181
Rab36_Rab34cd041080.000144187
Rab28cd041091.8e-094189
Rab35cd041104e-204188
Rab39cd041112.9e-094181
Rab26cd041127e-104186
Rab4cd041132.3e-144163
Rab33B_Rab33Acd041152.1e-204165
Rab9cd041163.5e-214163
Rab15cd041176e-194163
Rab24cd041188e-084186
RJLcd041194.8e-114165
Rab12cd041209.1e-054187
Tc10cd041357.4e-134160
RalA_RalBcd041395.8e-1054166
RRP22cd041427.3e-074189
RGKcd041482.7e-084189
Rhes_likecd041432.3e-124189
Rab21cd041233e-264164
Rab14cd041222.8e-244166
RabL2cd041241.8e-064167
cd041251e-124175
Wrch_1cd041303.5e-104163
Rho4_likecd041325.7e-154189
Arf_Arlcd008781.7e-055162
Rascd008762.1e-975163
Miro1cd018932.1e-055158
Rho3cd041348.8e-085189
Ras2cd041446.6e-695189
RERG_RasL11_likecd041464.6e-315165
Ras_dvacd041477e-145186
Rab27Acd041273.6e-195168
Era_likecd008806.8e-058163
Ras_like_GTPasecd008822.6e-568161
Raspfam000718.7e-945165
small_GTPasesmart000108.9e-541167
RASsmart001733.5e-1194166
RABsmart001752.1e-374166
Miropfam084771.9e-185119
RHOsmart001742.5e-126166
RANsmart001760.000689177

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_006847Polymorphismp.GLN61ARGN/A
Swiss-ProtVAR_006846Polymorphismp.GLN61LYSN/A
Swiss-ProtVAR_006845Polymorphismp.GLY13ARGN/A
Swiss-ProtVAR_063084Diseasep.GLY13ASPAutoimmune lymphoproliferative syndrome 4 (ALPS4)
Swiss-ProtVAR_021194Polymorphismp.GLY12CYSN/A
Swiss-ProtVAR_063086Diseasep.GLY60GLUNoonan syndrome 6 (NS6)
Swiss-ProtVAR_063085Diseasep.THR50ILENoonan syndrome 6 (NS6)
OMIM164790.0002 Diseasep.GLN61ARGTHYROID CARCINOMA, FOLLICULAR, SOMATIC||EPIDERMAL NEVUS, SOMATIC, INCLUDED
OMIM164790.0001 Diseasep.GLY13ARGRECTAL CANCER, SOMATIC
OMIM164790.0007 Diseasep.GLY12ASPEPIDERMAL NEVUS, SOMATIC
OMIM164790.0003 Diseasep.GLY13ASPAUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE IV||JUVENILE MYELOMONOCYTIC LEUKEMIA, INCLUDED;;||NOONAN SYNDROME 6, INCLU
OMIM164790.0005 Diseasep.GLY60GLUNOONAN SYNDROME 6
OMIM164790.0006 Diseasep.PRO34LEUEPIDERMAL NEVUS, SOMATIC
OMIM164790.0004 Diseasep.THR50ILENOONAN SYNDROME 6



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