Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: P05543
1351236

THBG_HUMAN RecName: Full=Thyroxine-binding globulin; AltName: Full=Serpin A7; AltName: Full=T4-binding globulin; Flags: Precursor

Known Diseases associated with this Protein:
  THYROXINE-BINDING GLOBULIN DEFICIENCY (TBG DEFICIENCY)
6
3
0
2
7
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

COG4826 - COG4826
HCII - cd02047
PAI-1_nexin-1 - cd02051
antithrombin-III_lik - cd02045
PEDF - cd02052
hsp47 - cd02046
PZI - cd02055
alpha2AP - cd02053
PAI-2 - cd02058
ovalbumin_like - cd02059
maspin_like - cd02057
bacterial_SERPIN - cd02049
ov-serpin - cd02044
plant_SERPIN - cd02043
Serpin - pfam00079
alpha-1-antitrypsin_ - cd02056
SERPIN - cd00172
angiotensinogen - cd02054
neuroserpin - cd02048
C1_inh - cd02050
SERPIN - smart00093


Swiss-Prot Protein: P05543
Identical to: NP_000345
   Default View:























Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PAI-1_nexin-1cd020512.7e-1736412
antithrombin-III_likcd020458.2e-3938409
PEDFcd020526.4e-1539412
hsp47cd020463.6e-1840409
alpha2APcd020531e-1141409
PZIcd020554.5e-3741409
ov-serpincd020441.5e-4342412
bacterial_SERPINcd020499e-4042409
maspin_likecd020572.9e-1742412
ovalbumin_likecd020591.1e-4042412
PAI-2cd020586.8e-2942412
plant_SERPINcd020432.8e-1744412
SERPINcd001726.6e-10645409
angiotensinogencd020548.9e-1545412
alpha-1-antitrypsin_cd020566.9e-24745409
neuroserpincd020483.8e-3147415
C1_inhcd020501.5e-1147409
COG4826COG48261.1e-331415
Serpinpfam000792.3e-15244412
SERPINsmart000935.4e-18451412

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_007104Diseasep.ALA133PROThyroxine-binding globulin deficiency (TBG deficiency)
Swiss-ProtVAR_007106Polymorphismp.ALA211THRN/A
dbSNPrs1050086 Polymorphismp.ASP191ASNN/A
Swiss-ProtVAR_007109Diseasep.HIS351TYRThyroxine-binding globulin deficiency (TBG deficiency)
Swiss-ProtVAR_007103Diseasep.ILE116ASNThyroxine-binding globulin deficiency (TBG deficiency)
dbSNPrs1804495 Polymorphismp.LEU303PHEN/A
Swiss-ProtVAR_007107Diseasep.LEU247PROThyroxine-binding globulin deficiency (TBG deficiency)
Swiss-ProtVAR_007110Diseasep.PRO383LEUThyroxine-binding globulin deficiency (TBG deficiency)
Swiss-ProtVAR_007102Diseasep.SER43THRThyroxine-binding globulin deficiency (TBG deficiency)



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258