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Results for the Protein: P07477
136408

TRY1_HUMAN RecName: Full=Trypsin-1; AltName: Full=Beta-trypsin; AltName: Full=Cationic trypsinogen; AltName: Full=Serine protease 1; AltName: Full=Trypsin I; Contains: RecName: Full=Alpha-trypsin chain 1; Contains: RecName: Full=Alpha-trypsin chain 2; Flags: Precursor

Known Diseases associated with this Protein:
  PANCREATITIS, HEREDITARY
  PANCREATITIS, HEREDITARY (PCTT)
  RECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE
19
1
7
0
13
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Default View:

Tryp_SPc - smart00020
Trypsin - pfam00089
Tryp_SPc - cd00190


Swiss-Prot Protein: P07477
Identical to: NP_002760
   Default View:





Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Tryp_SPccd001903.8e-11624242
Trypsinpfam000891.9e-10724239
Tryp_SPcsmart000202.2e-11223239

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_011693Diseasep.ALA16VALPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_011655Diseasep.ARG116CYSPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_012713Diseasep.ARG122CYSPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_006721Diseasep.ARG122HISPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_006720Diseasep.ASN29ILEPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_037908Diseasep.ASN54SERPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_012712Diseasep.ASN29THRPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_011652Diseasep.ASP22GLYPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_011656Diseasep.CYS139PHEPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_037909Diseasep.GLU79LYSPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_011654Diseasep.LEU104PROPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_011653Diseasep.LYS23ARGPancreatitis, hereditary (PCTT)
Swiss-ProtVAR_036299Polymorphismp.THR137METN/A
OMIM276000.0011 Diseasep.ALA121THRRECLASSIFIED - VARIANT OF UNKNOWN SIGNIFICANCE
OMIM276000.0012 Diseasep.ARG116CYSPANCREATITIS, HEREDITARY
OMIM276000.0009 Diseasep.ARG122CYSPANCREATITIS, HEREDITARY
OMIM276000.0002 Diseasep.ASN29ILEPANCREATITIS, HEREDITARY
OMIM276000.0007 Diseasep.ASN54SERPANCREATITIS, HEREDITARY
OMIM276000.0006 Diseasep.GLU79LYSPANCREATITIS, HEREDITARY
OMIM276000.0003 Diseasep.LYS23ARGPANCREATITIS, HEREDITARY



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