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Results for the Protein: P17948
143811474

VGFR1_HUMAN RecName: Full=Vascular endothelial growth factor receptor 1; Short=VEGFR-1; AltName: Full=Fms-like tyrosine kinase 1; Short=FLT-1; AltName: Full=Tyrosine-protein kinase FRT; AltName: Full=Tyrosine-protein kinase receptor FLT; Short=FLT; AltName: Full=Vascular permeability factor receptor; Flags: Precursor
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

IG - smart00409
IG_like - smart00410
ig - pfam00047
Ig1_VEGFR_like - cd05742
Ig1_VEGFR - cd05862
Ig - cd00096
I-set - pfam07679
Ig4_PDGFR-alpha - cd05859
Ig2_IL1R_like - cd05757
Ig2_FGFR_like - cd05729
Ig2_FGFRL1-like - cd05856
Ig_Titin_like - cd05748
Ig2_VEGFR-1 - cd07702
Ig2_VEGFR-2 - cd05864
Ig2_VEGFR - cd04976
Ig2_VEGFR-3 - cd05863
IGc2 - smart00408
Ig1_Robo - cd07693
Ig_CEACAM_D4 - cd05740
Ig5_NCAM-1_like - cd05732
Ig3_Contactin-1 - cd05851
Ig3_Contactin_like - cd04968
Ig3_NCAM-1_like - cd05730
Ig1_Neogenin - cd05722
Ig_Myomesin_like_C - cd05737
Ig4_Contactin-2-like - cd05728
Ig2_Robo - cd05724
Ig_C5_MyBP-C - cd05894
V-set - pfam07686
Ig2_FGFR - cd05857
Ig4_L1-NrCAM_like - cd04978
Ig_Perlecan_D2_like - cd05743
Ig5_Contactin_like - cd04969
Ig4_NrCAM - cd05868
Ig1_PVR_like - cd05718
Ig3_Peroxidasin - cd05745
Ig4_Neogenin - cd05723
Ig2_Follistatin_like - cd05736
Ig_Pro_neuregulin - cd05750
Ig4_Peroxidasin - cd05746
Ig2_PTK7 - cd05760
Ig_1 - cd05763
Ig6_NrCAM - cd05874
Ig_Myotilin_C_like - cd05744
Ig6_L1-CAM_like - cd05733
Ig3_Robo - cd05725
Ig3_L1-CAM_like - cd05731
Ig7_DSCAM - cd05734
Ig2_RPTP_IIa_LAR_lik - cd05738
Ig3_L1-CAM - cd05876
Ig_Myotilin_C - cd05892
Ig_Palladin_C - cd05893
Ig4_L1-CAM_like - cd05867
PTKc_CSF-1R - cd05106
PTKc_PDGFR_alpha - cd05105
PTKc_PDGFR_beta - cd05107
PTKc_Kit - cd05104
PTKc_PDGFR - cd05055
STKc_PAK - cd06614
STKc_myosinIIIA - cd06638
STKc_p38 - cd07851
PTKc_FGFR1 - cd05098
PTKc_FGFR2 - cd05101
PTKc_FGFR - cd05053
PTKc_FGFR4 - cd05099
PTKc_FGFR3 - cd05100
PTKc_Tie2 - cd05088
STKc_CDK9 - cd07865
STKc_SLK_like - cd06611
STKc_CDK10 - cd07845
STKc_ASK - cd06624
PTKc_VEGFR2 - cd05103
PTKc_VEGFR3 - cd05102
PTKc_EGFR_like - cd05057
PTKc_VEGFR - cd05054
PTKc_Src_like - cd05034
PTKc_InsR_like - cd05032
PTKc_Frk_like - cd05068
PTKc_ALK_LTK - cd05036
PTKc_Csk_like - cd05039
PTKc_FAK - cd05056
PTKc_InsR - cd05061
PTKc_Lck_Blk - cd05067
PTKc_Chk - cd05083
PTKc_Srm_Brk - cd05148
PTKc_Abl - cd05052
PTKc_IGF-1R - cd05062
PTKc_Fyn_Yrk - cd05070
PTKc_Yes - cd05069
PTKc_Lyn - cd05072
STKc_CDK12 - cd07864
PTKc_Csk - cd05082
PTKc_Hck - cd05073
PTKc_Src - cd05071
PTKc_TrkC - cd05094
PTKc_DDR - cd05051
PTKc_EphR_A2 - cd05063
PTKc_Ror - cd05048
PTKc_Musk - cd05050
PTK_CCK4 - cd05046
PTKc_Trk - cd05049
PTKc_EphR_A10 - cd05064
PTKc_Ror1 - cd05090
PTKc_DDR1 - cd05096
PTKc_DDR_like - cd05097
PTKc_DDR2 - cd05095
PTKc_TrkB - cd05093
PTKc_Ror2 - cd05091
PTKc_TrkA - cd05092
STKc_ERK1_2_like - cd07849
PTKc_Btk_Bmx - cd05113
PTKc_Jak_rpt2 - cd05038
PTKc_EphR - cd05033
PTKc_Itk - cd05112
PTKc_Tec_Rlk - cd05114
PTK_HER3 - cd05111
PTKc_EphR_A - cd05066
PTKc_Tec_like - cd05059
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_EphR_B - cd05065
PTKc_Tyk2_rpt2 - cd05080
PTKc_Jak1_rpt2 - cd05079
PTKc_EGFR - cd05108
PTK_Ryk - cd05043
STKc_myosinIII_like - cd06608
STKc_MAP4K3_like - cd06613
STKc_CdkB_plant - cd07837
PKc_MAPKK_PBS2_like - cd06622
STKc_Nek6_Nek7 - cd08224
PKc_MKK3_6 - cd06617
STKc_OSR1_SPAK - cd06610
STKc_MST3_like - cd06609
PKc_MAPKK_plant_like - cd06623
SPS1 - COG0515
PTKc_Tie1 - cd05089
PKc_MAPKK - cd06605
STKc_CDKL - cd07833
STKc_CNK2-like - cd08530
STKc_Cdc7_like - cd06627
STKc_MEKK1 - cd06630
STKc_MAPKKK - cd06606
PKc_STE - cd05122
PTKc_RET - cd05045
STKc_YSK4 - cd06631
STKc_MEKK1_plant - cd06632
STKc_MPK1 - cd07857
STKc_CDK7 - cd07841
STKc_MAPK - cd07834
STKc_CCRK - cd07832
STKc_Nek - cd08215
STKc_CDK_like - cd07829
PTKc_Axl - cd05075
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
STKc_PKN - cd05589
STKc_MAK_like - cd07830
Pkinase_Tyr - pfam07714
TyrKc - smart00219
STYKc - smart00221
Pkinase - pfam00069
STKc_PDK1 - cd05581
STKc_CMGC - cd05118
STKc_MEKK3_like - cd06625
STKc_CDK1_like - cd07835
STKc_CDK9_like - cd07840
STKc_CDKL2_3 - cd07846
PTKc_Syk_like - cd05060
PTKc_Met_Ron - cd05058
PTKc_c-ros - cd05044
PTKc_Fer - cd05085
PTKc_Aatyk2 - cd05086
PTKc_Fes - cd05084
PTKc_Fes_like - cd05041
PTKc_Tie - cd05047
PTKc - cd00192
PTK_Jak_rpt1 - cd05037
PTKc_Ack_like - cd05040
PTKc_Aatyk - cd05042
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc_Syk - cd05116
STKc_Nek2 - cd08217
STKc_RSK_N - cd05582
STKc_PKC - cd05570
PTKc_Zap-70 - cd05115
STKc_NAK1_like - cd06917
STKc_Nek9 - cd08221
STKc_AGC - cd05123
STKc_MST1_2 - cd06612
PKc - cd00180
S_TKc - smart00220
PTKc_HER2 - cd05109
STKc_MAPKKK_Byr2_lik - cd06628
PTKc_HER4 - cd05110
STKc_PAK6 - cd06659
STKc_PAK1 - cd06654
STKc_PAK3 - cd06656
STKc_PAK2 - cd06655
STKc_PAK_II - cd06648
STKc_Nek3 - cd08219
STKc_cPKC - cd05587
STKc_PKB - cd05571
STKc_CDKL1_4 - cd07847
STKc_PKB_alpha - cd05594
STKc_Nek4 - cd08223
STKc_Nek5 - cd08225
STKc_Nek7 - cd08229
STKc_Nek11 - cd08222
STKc_nPKC_theta_delt - cd05592
STKc_SGK2 - cd05603
STKc_nPKC_theta - cd05619
STKc_beta_ARK - cd05606
PKc_MKK4 - cd06616
PTK_Jak2_Jak3_rpt1 - cd05078
STKc_Nek1 - cd08218
STKc_Nek6 - cd08228
STKc_FA2-like - cd08529
STKc_GRK - cd05577
PKc_MKK7 - cd06618
STKc_CDK5 - cd07839
STKc_NLK - cd07853
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MEKK4 - cd06626
STKc_Yank1 - cd05578
STKc_BUR1 - cd07866
STKc_CDC2L1 - cd07843
KIND - smart00750


Swiss-Prot Protein: P17948
Identical to: NP_002010
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Ig1_VEGFR_likecd057426.5e-41245327
Ig1_VEGFRcd058624.5e-12245332
Igcd000961e-05248327
Ig4_PDGFR-alphacd058592.4e-05333426
Ig2_IL1R_likecd057574.2e-05337428
Ig2_FGFR_likecd057290.00012341426
Ig2_FGFRL1-likecd058560.00067341426
Ig_Titin_likecd057489.1e-05352424
Igcd000964.2e-05353419
Ig2_VEGFRcd049765.7e-46353424
Ig2_VEGFR-3cd058631.2e-11353424
Ig2_VEGFR-2cd058641.2e-08353424
Ig2_VEGFR-1cd077022.7e-57353424
Igcd000960.00052573654
Ig5_NCAM-1_likecd057320.00078660748
Ig_CEACAM_D4cd057406.8e-05660749
Ig3_Contactin-1cd058515.3e-07660749
Ig1_Robocd076938.4e-07660749
Ig3_Contactin_likecd049682.7e-07661749
Ig3_NCAM-1_likecd057301.6e-09661751
Ig1_Neogenincd057220.001662748
Ig_Myomesin_like_Ccd057370.00012663748
Ig4_Contactin-2-likecd057282.2e-07664748
Ig2_IL1R_likecd057576.6e-06666750
Ig2_Robocd057248.3e-09668748
Ig_C5_MyBP-Ccd058940.00062668750
Ig2_FGFRL1-likecd058569.8e-05669748
Ig2_FGFR_likecd057294.4e-07670748
Ig2_FGFRcd058575.9e-06670748
Ig5_Contactin_likecd049695e-07675748
Ig4_L1-NrCAM_likecd049781.6e-06675749
Ig_Perlecan_D2_likecd057433.8e-06675748
Ig4_NrCAMcd058680.0005675749
Ig1_PVR_likecd057183.1e-05676749
Ig3_Peroxidasincd057456.8e-07676748
Ig4_Neogenincd057239e-05677748
Ig_Titin_likecd057480.00025677748
Igcd000965e-16678745
Ig3_Robocd057255.4e-06678748
Ig3_L1-CAM_likecd057312e-06678749
Ig7_DSCAMcd057340.00035678748
Ig2_Follistatin_likecd057361.7e-07678751
Ig2_RPTP_IIa_LAR_likcd057381.3e-06678747
Ig6_L1-CAM_likecd057330.00011678748
Ig_Myotilin_C_likecd057442e-05678748
Ig4_Peroxidasincd057463.1e-06678747
Ig_Pro_neuregulincd057500.00019678746
Ig2_PTK7cd057605.7e-05678753
Ig_1cd057631.3e-11678749
Ig6_NrCAMcd058746.4e-06678748
Ig3_L1-CAMcd058761.2e-05678749
Ig_Myotilin_Ccd058920.00028678748
Ig_Palladin_Ccd058933.1e-05678748
Ig4_L1-CAM_likecd058670.00086680749
PTKc_CSF-1Rcd051064.3e-1337851159
PTKc_PDGFRcd050551.6e-1577891158
PTKc_Kitcd051041.6e-1347891158
PTKc_PDGFR_betacd051077.9e-1157891159
PTKc_PDGFR_alphacd051054.1e-1227891160
STKc_PAKcd066141.6e-087991170
STKc_myosinIIIAcd066380.000918041156
STKc_p38cd078516.4e-068101230
PTKc_FGFR1cd050987.8e-1038121165
PTKc_FGFR2cd051011.5e-1048121165
PTKc_FGFRcd050533e-1338131159
PTKc_FGFR4cd050991.3e-1018131172
PTKc_FGFR3cd051004.4e-988131197
PTKc_Tie2cd050881.4e-518151189
STKc_CDK9cd078650.000878161194
STKc_SLK_likecd066112e-068171153
STKc_ASKcd066240.000798181158
STKc_CDK10cd078450.000158181204
PTKc_VEGFRcd050541.3e-2258191161
PTKc_EGFR_likecd050571.8e-438191173
PTKc_VEGFR2cd051032.5e-2378191161
PTKc_VEGFR3cd051022.9e-2128191161
PTKc_InsR_likecd050321.3e-588201156
PTKc_Src_likecd050341.3e-478201157
PTKc_ALK_LTKcd050364.4e-578201156
PTKc_Csk_likecd050391.5e-398201157
PTKc_Ablcd050522.8e-528201158
PTKc_FAKcd050567.4e-498201162
PTKc_InsRcd050612.2e-428201167
PTKc_Lck_Blkcd050672.7e-388201157
PTKc_Frk_likecd050684.4e-548201157
PTKc_IGF-1Rcd050623.9e-408201156
PTKc_Fyn_Yrkcd050702e-318201157
PTKc_Srccd050711.6e-238201159
PTKc_Lyncd050725.1e-348201157
PTKc_Hckcd050733.6e-388201157
PTKc_Yescd050693.1e-248201157
PTKc_Cskcd050821.1e-508201157
PTKc_Chkcd050831.2e-538201157
PTKc_Srm_Brkcd051481.2e-408201157
STKc_CDK12cd078640.000148201183
PTK_CCK4cd050463e-358211156
PTKc_Trkcd050491.7e-488211156
PTKc_Muskcd050508.8e-658211156
PTKc_Rorcd050481.5e-498211157
PTKc_DDRcd050513.9e-308211156
PTKc_EphR_A2cd050632.8e-278211158
PTKc_EphR_A10cd050641.1e-208211158
PTKc_Ror1cd050903.2e-378211157
PTKc_Ror2cd050911.1e-338211157
PTKc_TrkAcd050922.5e-398211160
PTKc_TrkBcd050934e-348211165
PTKc_TrkCcd050944.2e-218211165
PTKc_DDR2cd050958.2e-358211156
PTKc_DDR1cd050962e-308211156
PTKc_DDR_likecd050971.6e-308211156
STKc_ERK1_2_likecd078490.000558211213
PTKc_EphRcd050331.5e-278221158
PTKc_Jak_rpt2cd050385.4e-458221158
PTKc_EphR_Bcd050652.5e-268221158
PTKc_EphR_Acd050661.3e-328221158
PTKc_Tec_likecd050591.3e-338221155
PTKc_Jak1_rpt2cd050796.4e-248221158
PTKc_Tyk2_rpt2cd050801.3e-138221159
PTKc_Jak2_Jak3_rpt2cd050812.4e-248221158
PTKc_EGFRcd051085.7e-208221215
PTK_HER3cd051114.7e-198221173
PTKc_Itkcd051125.1e-348221155
PTKc_Btk_Bmxcd051131e-428221155
PTKc_Tec_Rlkcd051143.4e-358221155
PTK_Rykcd050432.7e-228231157
STKc_myosinIII_likecd066085.2e-088231158
STKc_MAP4K3_likecd066133.4e-078231155
PKc_MAPKK_PBS2_likecd066221.4e-058241197
STKc_CdkB_plantcd078375.6e-058241183
STKc_Nek6_Nek7cd082249.5e-058241160
PTKc_Tie1cd050891.8e-588251188
PKc_MAPKKcd066052.9e-078251163
STKc_MST3_likecd066092.2e-068251169
STKc_OSR1_SPAKcd066101.7e-058251152
PKc_MKK3_6cd066171.1e-068251174
PKc_MAPKK_plant_likecd066231.6e-098251157
STKc_CDKLcd078331e-068251150
SPS1COG05153.9e-218251305
PTKc_RETcd050452.3e-978261161
PKc_STEcd051223.1e-108261152
STKc_MAPKKKcd066066.5e-168261151
STKc_Cdc7_likecd066273.4e-118261151
STKc_MEKK1cd066300.000538261153
STKc_YSK4cd066313e-068261158
STKc_MEKK1_plantcd066321.4e-068261151
STKc_CCRKcd078324.9e-068261148
STKc_MAPKcd078340.000158261165
STKc_CDK7cd078414e-058261151
STKc_MPK1cd078572.6e-058261211
STKc_Nekcd082151.1e-108261156
STKc_CNK2-likecd085301.1e-068261151
PTKc_Axl_likecd050353.4e-528271158
PTKc_Tyro3cd050741.9e-448271158
PTKc_Axlcd050755.3e-428271158
STKc_PKNcd055895.4e-058271220
STKc_CDK_likecd078295.5e-098271147
STKc_MAK_likecd078307.7e-078271147
STKc_CMGCcd051183.6e-088281147
STKc_PDK1cd055813e-088281150
STKc_MEKK3_likecd066253.3e-058281156
STKc_CDK1_likecd078350.000148281181
STKc_CDK9_likecd078401.1e-068281163
STKc_CDKL2_3cd078463.3e-068281158
PTKccd001925e-1498311155
PTK_Jak_rpt1cd050372.8e-058311155
PTKc_Ack_likecd050405.2e-378311156
PTKc_Aatykcd050423.8e-118311156
PTKc_Tiecd050473.2e-638311159
PTKc_Fes_likecd050415.6e-358311156
PTKc_c-roscd050447.8e-448311156
PTKc_Met_Roncd050582.6e-528311160
PTKc_Syk_likecd050602.3e-318311159
PTKc_Fercd050857.7e-388311156
PTKc_Aatyk2cd050868.8e-078311157
PTKc_Fescd050841.5e-328311156
PTKc_Aatyk1_Aatyk3cd050871.5e-148311156
PTKc_Sykcd051161.1e-288311159
STKc_PKCcd055702.3e-068311220
STKc_RSK_Ncd055820.00098311220
STKc_Nek2cd082176.4e-078311158
PTKc_Zap-70cd051151.5e-288321159
STKc_NAK1_likecd069174.1e-068321163
PKccd001805.9e-498331154
STKc_AGCcd051233.8e-088331149
STKc_MST1_2cd066122.7e-058331151
STKc_Nek9cd082218.5e-058331158
PTKc_HER2cd051091.1e-228721173
STKc_MAPKKK_Byr2_likcd066284.3e-068761156
PTKc_HER4cd051101.4e-118791202
STKc_PAK6cd066590.000118871180
STKc_PAK1cd066540.000318871186
STKc_PAK_IIcd066488.2e-058881170
STKc_PAK2cd066550.000958881180
STKc_PAK3cd066560.000628881181
STKc_Nek3cd082193.7e-068881157
STKc_cPKCcd055870.000428921221
STKc_PKB_alphacd055940.000218931228
STKc_PKBcd055710.000398931225
STKc_CDKL1_4cd078470.000418931181
STKc_Nek4cd082235.2e-059021156
STKc_Nek5cd082258.6e-059041154
STKc_Nek11cd082226e-059061156
STKc_Nek7cd082299.2e-069061160
STKc_nPKC_theta_deltcd055924.7e-059071222
STKc_SGK2cd056030.000889071221
STKc_nPKC_thetacd056193.6e-059071222
STKc_beta_ARKcd056060.0019081172
PKc_MKK4cd066160.000159081176
PTK_Jak2_Jak3_rpt1cd050780.000229101155
STKc_Nek1cd082180.000189131158
STKc_Nek6cd082280.000429171160
STKc_FA2-likecd085292.4e-069261157
STKc_GRKcd055770.000219341172
PKc_MKK7cd066180.000139351164
STKc_CDK5cd078390.000499411182
STKc_NLKcd078530.000769441258
STKc_MAPKKK_Bck1_likcd066293.8e-079601148
STKc_MEKK4cd066261.3e-059641151
STKc_Yank1cd055780.000759701157
STKc_BUR1cd078660.000519711147
STKc_CDC2L1cd078430.000289741147
igpfam000470.00053245313
igpfam000474.4e-05570638
igpfam000479.7e-10675733
Pkinasepfam000691.6e-288271154
IGsmart004094.9e-05143225
IG_likesmart004104.9e-05143225
IGsmart004093.7e-09237329
IG_likesmart004103.7e-09237329
I-setpfam076791.3e-05332426
IGsmart004090.00014342425
IG_likesmart004100.00014342425
IG_likesmart004100.00072439553
IGsmart004095.9e-08562658
IG_likesmart004105.9e-08562658
IGc2smart004081e-06569643
I-setpfam076791.4e-22661748
IGsmart004091.9e-20667749
IG_likesmart004101.9e-20667749
V-setpfam076860.0007669748
IGc2smart004084.3e-21674738
Pkinase_Tyrpfam077141e-1648271154
TyrKcsmart002199.4e-1658271154
STYKcsmart002211.1e-548271127
S_TKcsmart002207.6e-318371158
KINDsmart007500.000139751164

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_042047Polymorphismp.ARG281GLNN/A
Swiss-ProtVAR_042049Polymorphismp.ARG781GLNN/A
Swiss-ProtVAR_042051Polymorphismp.GLU982ALAN/A
Swiss-ProtVAR_042046Polymorphismp.GLU144LYSN/A
Swiss-ProtVAR_049719Polymorphismp.ILE128LEUN/A
Swiss-ProtVAR_042048Polymorphismp.LEU422ILEN/A
Swiss-ProtVAR_042052Polymorphismp.LEU1061VALN/A
Swiss-ProtVAR_042045Polymorphismp.LYS60THRN/A
Swiss-ProtVAR_042050Polymorphismp.MET938VALN/A



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