Results for the protein: Q8TCU6

Results for the Protein: Q8TCU6

148886999

57580

PREX1

NCBI, UniProt

PREX1_HUMAN RecName: Full=Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein; Short=P-Rex1; Short=PtdIns(3,4,5)-dependent Rac exchanger 1

			0 7 0 0 7

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Swiss-Prot Protein: Q8TCU6

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PH_SOS	cd01261	0.00093	269	394
PH1_FGD1	cd01219	0.0005	271	393
PH_Collybistin_ASEF	cd01224	2.2e-16	271	393
PH	cd00821	2.4e-10	274	390
PH-like	cd00900	0.00082	274	390
DEP_2_P-Rex	cd04440	1.4e-06	405	497
DEP_Epac	cd04437	4.4e-09	412	531
DEP_2_DEP6	cd04441	5.6e-21	412	494
DEP_1_DEP6	cd04442	6e-20	412	494
DEP_DEPDC5-like	cd04449	9.1e-06	413	494
DEP	cd04371	8.9e-26	414	493
DEP_1_P-Rex	cd04439	4.8e-58	414	494
DEP_PIKfyve	cd04448	2.2e-05	415	494
DEP_GPR155	cd04443	6.4e-08	415	494
DEP_2_P-Rex	cd04440	1.2e-65	506	598
DEP_2_DEP6	cd04441	4.3e-11	511	595
DEP_1_DEP6	cd04442	2.5e-12	513	595
DEP	cd04371	3e-22	515	594
DEP_1_P-Rex	cd04439	4.9e-13	515	595
DEP_GPR155	cd04443	2.9e-07	519	595
DEP_PIKfyve	cd04448	6.5e-05	523	595
RhoGEF	pfam00621	1.6e-61	54	239
PH	pfam00169	3.6e-06	272	392
DEP	pfam00610	1.6e-24	424	494
DEP	pfam00610	6.7e-24	526	595
RhoGEF	smart00325	1.2e-53	53	239
PH	smart00233	3.9e-11	272	392
DEP	smart00049	2.5e-26	422	496
DEP	smart00049	2.4e-23	524	597

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_057192	Polymorphism	p.ALA1118THR	N/A
Swiss-Prot	VAR_057191	Polymorphism	p.ARG696CYS	N/A
Swiss-Prot	VAR_061799	Polymorphism	p.GLN786HIS	N/A
Swiss-Prot	VAR_023211	Polymorphism	p.LYS1340GLU	N/A
Swiss-Prot	VAR_023212	Polymorphism	p.SER1559THR	N/A
Swiss-Prot	VAR_023210	Polymorphism	p.VAL1240ILE	N/A
Swiss-Prot	VAR_061798	Polymorphism	p.VAL659MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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