Results for the protein: Q8NB66

Results for the Protein: Q8NB66

148887448

440279

UNC13C

NCBI, UniProt

UN13C_HUMAN RecName: Full=Protein unc-13 homolog C; AltName: Full=Munc13-3

			0 5 0 3 2

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Swiss-Prot Protein: Q8NB66

Identical to: NP_001074003

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
C2A_Munc13-like	cd08676	7.4e-09	1189	1329
C2A_RIM1alpha	cd04031	2.3e-06	1195	1330
C2A_Synaptotagmin-7	cd08386	0.00037	1203	1331
C2_Perforin	cd04032	3.9e-07	1205	1331
C2_Intersectin	cd08375	0.00067	1208	1349
C2A_Synaptotagmin-8	cd08387	0.00015	1208	1331
C2B_Synaptotagmin	cd00276	7.1e-06	1209	1329
C2_PKC_alpha_gamma	cd04026	1.7e-07	1209	1339
C2A_Rabphilin_Doc2	cd04035	5.2e-06	1211	1331
C2C_KIAA1228	cd04030	4.9e-07	1216	1330
C2B_Ferlin	cd04011	4.2e-05	1217	1322
C2_PLC_like	cd00275	2e-06	1219	1328
C2A_Synaptotagmin-1-	cd08385	6.3e-06	1219	1331
C2B_Synaptotagmin-7	cd08405	1.2e-05	1219	1345
C2B_Munc13	cd04027	1.7e-96	1220	1346
C2C_Tricalbin-like	cd04045	1.7e-07	1220	1352
C2A_Copine	cd04048	8e-07	1220	1339
C2C_MCTP_PRT	cd08377	2.1e-09	1220	1349
C2_NEDL1-like	cd08691	7.2e-06	1220	1347
C2B_RasA3	cd04010	8.2e-07	1221	1347
C2A_MCTP_PRT_plant	cd04022	2.1e-09	1221	1350
C2B_RasA1_RasA4	cd04025	1.6e-07	1221	1347
C2_cPLA2	cd04036	0.00015	1221	1331
C2_ArfGAP	cd04038	1.6e-07	1221	1352
C2A_MCTP_PRT	cd04042	1.1e-07	1221	1350
C2A_Rasal1_RasA4	cd04054	2.4e-07	1221	1348
C2E_Ferlin	cd04037	4e-05	1221	1344
C2_Smurf-like	cd08382	2.3e-06	1221	1347
C2A_RasGAP	cd08383	4.1e-06	1221	1348
C2B_Rabphilin_Doc2	cd08384	0.00048	1221	1329
C2	cd00030	1.6e-32	1222	1329
C2D_Tricalbin-like	cd04040	7e-09	1222	1345
C2A_fungal	cd04041	2.8e-07	1222	1333
C2A_Tricalbin-like	cd04044	4.5e-05	1222	1347
C2_Calpain	cd04046	2.8e-07	1222	1351
C2B_MCTP_PRT	cd08376	3.1e-07	1222	1344
C2_C21orf25-like	cd08678	0.00047	1222	1345
C2_Rab11-FIP_classI	cd08682	2.2e-07	1222	1351
C2_KIAA0528-like	cd08688	3e-05	1222	1312
C2B_RasGAP	cd08675	3.7e-07	1222	1342
C2_Munc13_fungal	cd04043	5.8e-08	1223	1324
C2B_Synaptotagmin-li	cd04050	7.6e-06	1223	1334
C2_fungal_Inn1p-like	cd08681	3.5e-05	1223	1348
C2A_Synaptotagmin-li	cd04024	2.6e-12	1224	1348
C2_NEDD4_NEDD4L	cd04033	3.6e-07	1224	1349
C2B_MCTP_PRT_plant	cd08378	1.3e-06	1224	1347
C2A_C2C_Synaptotagmi	cd08391	1.2e-10	1224	1348
C2A_Ferlin	cd08373	0.00024	1225	1360
C2_putative_Elicitor	cd04049	7.4e-05	1227	1350
C2D_Ferlin	cd04017	0.00038	1229	1354
C2B_Munc13-like	cd04009	0.00058	2042	2173
C2C_Munc13	cd08395	1.3e-90	2062	2181
C2	cd00030	2.9e-15	2063	2171
C1_1	pfam00130	4.1e-16	1098	1150
C2	pfam00168	4e-29	1222	1313
C2	pfam00168	3.7e-14	2063	2153
C1	smart00109	3.7e-18	1098	1147
C2	smart00239	5.2e-28	1221	1328
DUF1041	pfam06292	1e-63	1539	1646
Membr_traf_MHD	pfam10540	7.7e-83	1886	2028
C2	smart00239	2.1e-15	2062	2168

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_067540	Polymorphism	p.ASP304GLU	N/A
dbSNP	rs12437941	Polymorphism	p.GLY609SER	N/A
dbSNP	rs17731958	Polymorphism	p.SER942LEU	N/A
dbSNP	rs76762496	Polymorphism	p.TYR760ASN	N/A
Swiss-Prot	VAR_067541	Polymorphism	p.VAL2196ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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