Results for the protein: NP

Results for the Protein: NP_001219

15718704

841

CASP8

NCBI

caspase-8 isoform A precursor [Homo sapiens]

Known Diseases associated with this Protein:
BREAST CANCER, PROTECTION AGAINST

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
DED_PEA15	cd08338	0.00014	1	84
DED_c-FLIP_repeat2	cd08340	0.001	1	78
DED_Caspase_10_repea	cd08341	6.7e-08	1	83
DED	cd00045	6.4e-15	3	79
DED_Caspase_8_repeat	cd08333	3.1e-54	3	84
DED_Caspase-like_rep	cd08776	1.8e-21	3	79
DED_Caspase_8_10_rep	cd08792	9.1e-26	3	79
DED_c-FLIP_repeat1	cd08337	0.00018	4	87
DED_Caspase_10_repea	cd08814	2.7e-06	132	212
DED_Caspase_8_10_rep	cd08334	1.5e-37	134	212
DED_Caspase-like_rep	cd08775	4.1e-44	134	210
DED_Caspase_8_repeat	cd08813	5.2e-56	134	212
CASc	cd00032	2.1e-132	242	494
DED	pfam01335	1.4e-34	3	86
DED	pfam01335	6.4e-25	133	215
Peptidase_C14	pfam00656	2.3e-94	251	493
DED	smart00031	1.3e-32	1	80
DED	smart00031	1.3e-22	131	210
CASc	smart00115	9.7e-141	243	495

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1045485	Polymorphism	p.ASP302HIS	N/A
OMIM	601763.0003	Disease	p.ASP260HIS	BREAST CANCER, PROTECTION AGAINST

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