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Results for the Protein: NP_001098985
157502203

multidrug resistance-associated protein 4 isoform 2 [Homo sapiens]
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 The Domains on the Default View are decided by the Domain's E-Value.

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Default View:

SunT - COG2274
COG4178 - COG4178
MdlB - COG1132
PvdE - COG4615
CydD - COG4988
ABC_membrane - pfam00664
ArpD - COG4618
CydC - COG4987
ATM1 - COG5265
Uup - COG0488
COG1123 - COG1123
ABCC_SUR2 - cd03288
ABCC_CFTR1 - cd03291
TagH - COG1134
ModF - COG1119
COG4586 - COG4586
COG4674 - COG4674
ABCG_PDR_domain1 - cd03233
COG4181 - COG4181
Ttg2A - COG1127
ABCC_TAP - cd03248
ABCC_NFT1 - cd03369
PstB - COG1117
ABC_NatA_like - cd03267
ABC_RNaseL_inhibitor - cd03236
PhnK - COG4107
HisP - COG4598
ABC_KpsT_Wzt - cd03220
PotA - COG3842
ZnuC - COG1121
ABC_Carb_Monos_II - cd03215
ABC_Pro_Gly_Betaine - cd03294
PhnL - COG4778
AppF - COG4608
ProV - COG4175
DppF - COG1124
LivF - COG0410
sufC - COG0396
ABCG_PDR_domain2 - cd03232
ABCG_EPDR - cd03213
TauB - COG1116
CbiO - COG1122
BtuD - COG4138
SapF - COG4167
COG3638 - COG3638
MalK - COG3839
CcmA - COG4133
COG4136 - COG4136
ABC_CysA_sulfate_imp - cd03296
ABCC_MRP_domain2 - cd03244
CysA - COG1118
FepC - COG1120
GlnQ - COG1126
ArtP - COG4161
DppD - COG0444
ABC_ModC_molybdenum_ - cd03297
PhnK - COG1101
OpuBA - COG1125
ABCC_CFTR2 - cd03289
ABC_NatA_sodium_expo - cd03266
ABC_MetN_methionine_ - cd03258
ABC_NikE_OppD_transp - cd03257
CcmA - COG1131
SalX - COG1136
NatA - COG4555
TauB - COG4525
ThiQ - COG3840
COG4559 - COG4559
CeuD - COG4604
FtsE - COG2884
AbcC - COG1135
COG4619 - COG4619
ABC_putative_ATPase - cd03269
ABC_Carb_Solutes_lik - cd03259
ABC_Org_Solvent_Resi - cd03261
ABCC_Protease_Secret - cd03246
ABC_MJ0796_LolCDE_Ft - cd03255
ABC_MTABC3_MDL1_MDL2 - cd03249
ABC_HisP_GlnQ - cd03262
ABC_PstB_phosphate_t - cd03260
ABC_BcrA_bacitracin_ - cd03268
ABC_subfamily_A - cd03263
ABC_DrrA - cd03265
ABC_drug_resistance_ - cd03264
ABCC_ATM1_transporte - cd03253
ABCC_MRP_domain1 - cd03250
ABCF_EF-3 - cd03221
ABC_TM1139_LivF_bran - cd03224
ABCD_peroxisomal_ALD - cd03223
ABC_FeS_Assembly - cd03217
ABCC_MRP_Like - cd03228
ABC_DR_subfamily_A - cd03230
ABCC_MsbA - cd03251
ABCC_cytochrome_bd - cd03247
ABC_Class3 - cd03229
ABC_CcmA_heme_export - cd03231
ABC_OpuCA_Osmoprotec - cd03295
ABC_NrtD_SsuB_transp - cd03293
ABC_ModC_like - cd03299
ABC_MalK_N - cd03301
ABC_PotA_N - cd03300
ABC_Metallic_Cations - cd03235
ABC_cobalt_CbiO_doma - cd03225
ABC_ATPase - cd00267
ABC_Iron-Siderophore - cd03214
ABC_cobalt_CbiO_doma - cd03226
ABCC_SUR1_N - cd03290
ABCC_Hemolysin - cd03252
ABCG_White - cd03234
ABC_RNaseL_inhibitor - cd03222
ABC_Class2 - cd03227
ABC_RNaseL_inhibitor - cd03237
ABC_UvrA_II - cd03271
ABCC_bacteriocin_exp - cd03245
ABC_ThiQ_thiamine_tr - cd03298
ABC_FtsE_transporter - cd03292
ABCC_Glucan_exporter - cd03254
YhbG - COG1137
ABC_PhnC_transporter - cd03256
LivG - COG0411
ABC_Carb_Monos_I - cd03216
ABC_YhbG - cd03218
ABC_Mj1267_LivG_bran - cd03219
ModC - COG4148
AAA - smart00382
ABC_tran - pfam00005




Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
UupCOG04880.0002221627
COG1123COG11235.8e-07276628
ABCC_SUR2cd032881e-06342635
ABCC_CFTR1cd032912e-67372653
TagHCOG11343.5e-08373638
ModFCOG11192.1e-10377617
ABCG_PDR_domain1cd032331.9e-07400615
ABCC_TAPcd032481.5e-13403611
ABCC_NFT1cd033696.1e-09403617
PstBCOG11171.5e-06403628
Ttg2ACOG11274.7e-09403640
ABC_KpsT_Wztcd032203.6e-11404615
ABC_RNaseL_inhibitorcd032360.001404628
ABC_NatA_likecd032674.5e-06404615
ABC_Carb_Monos_IIcd032155e-08406611
ABC_Pro_Gly_Betainecd032941.5e-10406630
ZnuCCOG11211.7e-12406645
ABCG_EPDRcd032131.5e-09407615
ABCG_PDR_domain2cd032320.00022407615
sufCCOG03969.4e-07407636
LivFCOG04101.3e-09407625
TauBCOG11161.5e-11407641
DppFCOG11245e-09407642
CbiOCOG11224.6e-11407640
ABCC_MRP_domain2cd032447.9e-14408617
ABC_CysA_sulfate_impcd032967.1e-10408629
CysACOG11182.5e-10408707
FepCCOG11209.1e-13408644
GlnQCOG11262.5e-07408631
ABC_MetN_methionine_cd032583e-10409624
ABC_NikE_OppD_transpcd032571.1e-12409615
ABC_NatA_sodium_expocd032666.6e-09409615
ABCC_CFTR2cd032893.2e-06409687
ABC_ModC_molybdenum_cd032979.7e-10409615
DppDCOG04446.9e-06409688
PhnKCOG11012.2e-07409632
OpuBACOG11257.7e-07409705
CcmACOG11311.5e-18409679
SalXCOG11362.6e-13409617
AbcCCOG11356.1e-09409716
ABC_FeS_Assemblycd032172.1e-05410624
ABCD_peroxisomal_ALDcd032231.6e-10410611
ABC_TM1139_LivF_brancd032241.5e-09410623
ABCF_EF-3cd032213e-12410610
ABCC_MRP_Likecd032283.6e-62410610
ABC_DR_subfamily_Acd032301.2e-17410611
ABC_CcmA_heme_exportcd032311.3e-06410607
ABC_Class3cd032293.2e-14410610
ABCC_cytochrome_bdcd032472.1e-22410615
ABCC_MsbAcd032516.5e-19410631
ABCC_MRP_domain1cd032507.2e-129410610
ABCC_ATM1_transportecd032531.4e-14410634
ABC_MTABC3_MDL1_MDL2cd032499.9e-15410634
ABC_MJ0796_LolCDE_Ftcd032552.5e-11410611
ABCC_Protease_Secretcd032462.5e-18410611
ABC_Carb_Solutes_likcd032593.7e-14410615
ABC_Org_Solvent_Resicd032613.2e-11410631
ABC_HisP_GlnQcd032621.1e-10410611
ABC_PstB_phosphate_tcd032602.1e-10410620
ABC_drug_resistance_cd032642.6e-07410615
ABC_DrrAcd032655.3e-09410622
ABC_putative_ATPasecd032695.4e-08410615
ABC_subfamily_Acd032631.8e-10410622
ABC_BcrA_bacitracin_cd032687e-08410615
ABC_NrtD_SsuB_transpcd032937.4e-16410619
ABC_OpuCA_Osmoproteccd032952.6e-09410637
ABC_PotA_Ncd033001.1e-07410624
ABC_MalK_Ncd033011.1e-11410615
ABC_ModC_likecd032991.9e-10410621
ABC_ATPasecd002672.9e-45411610
ABC_Iron-Siderophorecd032146.9e-14411615
ABC_cobalt_CbiO_domacd032252.6e-18411610
ABC_cobalt_CbiO_domacd032261.6e-11411612
ABC_Metallic_Cationscd032352e-13411615
ABCC_Hemolysincd032529e-12412634
ABCC_SUR1_Ncd032906.1e-49412610
ABC_RNaseL_inhibitorcd032224.5e-05413628
ABCG_Whitecd032341e-07413615
ABC_Class2cd032270.00032417618
ABC_RNaseL_inhibitorcd032374.7e-05419639
ABCC_bacteriocin_expcd032452.2e-18421615
ABC_UvrA_IIcd032710.00065421617
ABC_ThiQ_thiamine_trcd032981.7e-08421615
ABCC_Glucan_exportercd032544.2e-16422625
ABC_FtsE_transportercd032929.5e-08422611
ABC_Carb_Monos_Icd032161.7e-10423614
ABC_YhbGcd032189.7e-08423624
ABC_PhnC_transportercd032565e-11423627
LivGCOG04111.9e-08423619
YhbGCOG11374.4e-08423629
ABC_Mj1267_LivG_brancd032191.8e-09428626
SunTCOG22741.3e-083635
COG4178COG41787.1e-0557624
PvdECOG46154e-0582619
CydDCOG49881.8e-1691640
ABC_membranepfam006648.4e-2692365
ArpDCOG46181.1e-12104646
CydCCOG49872.2e-10130634
ATM1COG52653.3e-08151633
COG4586COG45861e-05378702
COG4674COG46740.00012398632
COG4181COG41817e-06402615
PhnKCOG41070.00027404628
HisPCOG45983.6e-05404632
PotACOG38422.4e-09405757
ProVCOG41751.6e-05406708
AppFCOG46084e-08406668
PhnLCOG47788.6e-06406606
COG3638COG36383.3e-11407642
MalKCOG38393.5e-10407708
BtuDCOG41387.2e-06407646
SapFCOG41673.5e-06407640
CcmACOG41331.5e-09408612
COG4136COG41361.4e-06408614
ArtPCOG41611.5e-08408633
FtsECOG28841.4e-07409619
ThiQCOG38401.4e-08409626
TauBCOG45252e-11409640
NatACOG45555.5e-12409639
COG4559COG45592.4e-07409647
CeuDCOG46043.6e-06409628
COG4619COG46192.8e-09410620
ModCCOG41488.5e-05430731
ABC_tranpfam000054.3e-29452563
AAAsmart003821.3e-18437616

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs11568659 Polymorphismp.ARG820ILEN/A
dbSNPrs3765534 Polymorphismp.GLU757LYSN/A
dbSNPrs11568658 Polymorphismp.GLY187TRPN/A
dbSNPrs11568681 Polymorphismp.LEU18ILEN/A
dbSNPrs2274407 Polymorphismp.LYS304ASNN/A
dbSNPrs9282570 Polymorphismp.MET744VALN/A



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