Results for the protein: Q8NEV4

Results for the Protein: Q8NEV4

160112826

53904

MYO3A

NCBI, UniProt

MYO3A_HUMAN RecName: Full=Myosin-IIIa

Known Diseases associated with this Protein:
DEAFNESS, AUTOSOMAL RECESSIVE 30

1

20

1

4

16

Tips:

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Swiss-Prot Protein: Q8NEV4

Identical to: NP_059129

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	4.9e-06	1	338
STKc_PAK	cd06614	9.2e-84	1	296
STKc_myosinIIIB	cd06639	7.2e-195	1	288
STKc_JNK2	cd07876	1.5e-05	1	323
STKc_ROCK2	cd05621	6e-07	2	352
STKc_ROCK1	cd05622	8.5e-06	2	353
STKc_myosinIIIA	cd06638	3.7e-256	2	287
STKc_PAK_II	cd06648	2.1e-48	2	300
STKc_TAO2	cd06634	4.2e-36	3	336
STKc_TAO1	cd06635	1.5e-30	3	335
STKc_TAO3	cd06633	8e-36	4	335
STKc_PAK_I	cd06647	7.8e-56	4	308
STKc_PAK1	cd06654	2e-50	4	315
STKc_PAK3	cd06656	4.3e-49	4	312
STKc_PAK2	cd06655	8e-51	4	319
STKc_TAO	cd06607	5e-44	5	324
STKc_p38	cd07851	3.9e-09	5	331
PKc_MKK7	cd06618	1e-18	6	307
STKc_MAP4K4_6	cd06636	4.2e-117	7	287
STKc_JNK3	cd07874	8.3e-05	7	342
STKc_p38gamma_MAPK12	cd07880	5.1e-07	7	327
STKc_MAP4K5	cd06646	5.4e-71	8	286
STKc_PAK4	cd06657	1.6e-33	8	302
STKc_PAK5	cd06658	2.9e-33	8	302
PTKc_FGFR4	cd05099	1.2e-06	9	307
STKc_PAK6	cd06659	2.4e-39	9	310
STKc_p38alpha_MAPK14	cd07877	0.00015	9	309
STKc_JNK	cd07850	3.9e-06	10	321
STKc_Sty1_Hog1	cd07856	5e-06	10	314
PTKc_FGFR1	cd05098	0.00033	11	294
STKc_p38delta_MAPK13	cd07879	0.00044	11	331
STKc_p38beta_MAPK11	cd07878	0.00019	11	331
STKc_ASK	cd06624	3.9e-35	12	287
STKc_ERK5	cd07855	2.9e-09	12	308
STKc_CDK9	cd07865	1.8e-12	12	287
PTK_CCK4	cd05046	9.3e-05	13	289
PTKc_TrkA	cd05092	7.8e-05	13	288
PTKc_FGFR2	cd05101	7.4e-05	13	294
PTKc_VEGFR3	cd05102	0.00011	13	285
PTKc_VEGFR2	cd05103	2.4e-05	13	291
PTKc_Src	cd05071	4.9e-06	14	288
PTKc_Hck	cd05073	3.1e-07	14	286
PTKc_Yes	cd05069	1.5e-06	14	290
PTKc_Csk	cd05082	1.5e-05	14	285
PTKc_InsR	cd05061	4.9e-06	14	297
PTKc_Lyn	cd05072	5.7e-07	14	286
STKc_myosinIII_like	cd06608	8.1e-217	14	287
STKc_TNIK	cd06637	9.9e-114	14	287
STKc_TEY_MAPK_plant	cd07858	1.8e-08	14	331
STKc_BUR1	cd07866	1.5e-09	14	287
STKc_PFTAIRE2	cd07870	1.1e-06	14	301
STKc_SLK_like	cd06611	1.5e-108	15	303
PTKc_EphR	cd05033	2.1e-06	16	287
PTKc_Tec_like	cd05059	2.7e-08	16	288
PTKc_EphR_A2	cd05063	7.7e-05	16	287
PTKc_EphR_A	cd05066	0.00016	16	287
PTKc_Itk	cd05112	6.8e-10	16	286
PTKc_Btk_Bmx	cd05113	1.2e-08	16	286
PTKc_Tec_Rlk	cd05114	3.9e-08	16	286
PTKc_EphR_B	cd05065	1.7e-05	16	287
PKc_MAPKK_Byr1_like	cd06620	1.9e-12	16	301
STKc_MST4	cd06640	2.2e-80	16	308
STKc_MST3	cd06641	3.9e-75	16	308
STKc_STK25-YSK1	cd06642	3.5e-82	16	308
STKc_SLK	cd06643	1.2e-77	16	310
STKc_MAP4K3	cd06645	1.1e-75	16	286
STKc_STK10_LOK	cd06644	2e-74	16	312
STKc_PCTAIRE_like	cd07844	6.4e-08	16	301
STKc_CDK10	cd07845	3.3e-09	16	296
STKc_MAPK4_6	cd07854	0.00052	16	310
STKc_ERK1_2_like	cd07849	3.7e-08	16	334
PTKc_InsR_like	cd05032	6.7e-08	17	283
PTKc_ALK_LTK	cd05036	1.4e-09	17	289
PTKc_Ror	cd05048	0.00035	17	270
PTKc_Trk	cd05049	5.5e-06	17	284
PTKc_Musk	cd05050	5.2e-08	17	284
PTKc_FGFR	cd05053	5.1e-08	17	288
PTKc_Lck_Blk	cd05067	1.3e-05	17	289
PTKc_Fyn_Yrk	cd05070	5.4e-06	17	290
PTKc_Tie2	cd05088	1.7e-05	17	310
PTKc_DDR2	cd05095	0.00061	17	289
PTKc_DDR_like	cd05097	0.00037	17	289
PTKc_FGFR3	cd05100	0.00041	17	326
PTKc_EGFR_like	cd05057	1.2e-06	17	291
STKc_MAP4K3_like	cd06613	1.6e-121	17	286
STKc_MEKK3_like	cd06625	2.2e-37	17	287
STKc_MST1_2	cd06612	5.2e-118	17	287
PTKc_Jak_rpt2	cd05038	2.5e-08	18	291
PTKc_EphR_A10	cd05064	0.00046	18	291
PTKc_TrkB	cd05093	5.2e-05	18	298
PTKc_EGFR	cd05108	1.7e-06	18	330
PTK_HER3	cd05111	6.1e-07	18	299
PKc_MKK4	cd06616	4.5e-18	18	305
PKc_MEK2	cd06649	1.9e-09	18	314
PKc_MEK1	cd06650	2.2e-09	18	318
STKc_MEKK2	cd06652	3.7e-18	18	288
STKc_MEKK3_like_1	cd06653	5.8e-24	18	287
STKc_MAPK15	cd07852	1.7e-10	18	305
STKc_PFTAIRE1	cd07869	2.4e-05	18	306
PK_STRAD	cd08216	5.5e-13	18	303
STKc_Nek6_Nek7	cd08224	1.3e-11	18	290
PTKc_FAK	cd05056	5e-09	19	295
PTKc_Chk	cd05083	3.9e-05	19	285
STKc_phototropin_lik	cd05574	1.7e-09	19	298
STKc_ROCK_NDR_like	cd05573	3.2e-13	19	342
STKc_PKA	cd05580	4e-14	19	332
STKc_PDK1	cd05581	5.2e-19	19	287
STKc_DMPK_like	cd05597	5.2e-08	19	371
STKc_LATS	cd05598	2.5e-07	19	358
STKc_NDR_like	cd05599	4.3e-08	19	333
STKc_Sid2p_Dbf2p	cd05600	7e-06	19	331
STKc_CRIK	cd05601	5.2e-11	19	343
STKc_MAST	cd05609	4.6e-08	19	347
STKc_PRKX_like	cd05612	3.2e-10	19	321
STKc_MRCK_alpha	cd05623	9.3e-07	19	340
STKc_LATS1	cd05625	4.7e-05	19	354
STKc_LATS2	cd05626	0.00027	19	354
STKc_NDR2	cd05627	1.2e-06	19	359
STKc_NDR1	cd05628	9.1e-08	19	338
STKc_MRCK_beta	cd05624	2.6e-06	19	339
STKc_NDR_like_fungal	cd05629	1.1e-05	19	366
PKc_MAPKK	cd06605	1.3e-37	19	292
STKc_OSR1_SPAK	cd06610	4.5e-73	19	287
PKc_MEK	cd06615	5e-15	19	305
PKc_MKK3_6	cd06617	4.9e-30	19	306
PKc_MKK5	cd06619	6.3e-22	19	317
PKc_MAPKK_Pek1_like	cd06621	6.4e-22	19	305
PKc_MAPKK_PBS2_like	cd06622	7.8e-22	19	332
PKc_MAPKK_plant_like	cd06623	3.9e-56	19	292
STKc_MST3_like	cd06609	4.2e-100	19	306
STKc_NAK1_like	cd06917	7.1e-59	19	306
STKc_CDKL	cd07833	3.1e-13	19	287
STKc_CdkB_plant	cd07837	6.9e-12	19	288
STKc_CDC2L1	cd07843	1.5e-10	19	287
STKc_CDKL2_3	cd07846	1.7e-11	19	287
STKc_CDKL1_4	cd07847	1.7e-15	19	287
STKc_CDK6	cd07862	2.8e-06	19	323
STKc_CDK12	cd07864	1.4e-11	19	287
STKc_PCTAIRE3	cd07871	1.3e-06	19	302
STKc_PCTAIRE2	cd07872	1.5e-06	19	338
STKc_PCTAIRE1	cd07873	1.1e-05	19	327
STKc_Nek7	cd08229	1.1e-11	19	287
STKc_Nek6	cd08228	4.8e-15	19	290
SPS1	COG0515	5.5e-56	19	486
PTKc_RET	cd05045	2.1e-05	20	290
PKc_STE	cd05122	1.7e-140	20	286
STKc_Yank1	cd05578	5.2e-16	20	287
STKc_MSK_N	cd05583	1.9e-13	20	306
STKc_cPKC	cd05587	7.8e-08	20	350
STKc_GRK4_like	cd05605	3.9e-08	20	313
STKc_MSK1_N	cd05613	1.9e-09	20	306
STKc_cPKC_alpha	cd05615	5.2e-08	20	350
STKc_cPKC_beta	cd05616	1.6e-06	20	350
STKc_MSK2_N	cd05614	8.8e-09	20	345
STKc_GRK6	cd05630	2.2e-05	20	308
STKc_GRK4	cd05631	2.1e-05	20	308
STKc_GRK5	cd05632	1.1e-06	20	308
STKc_MAPKKK	cd06606	6.8e-79	20	287
STKc_MEKK4	cd06626	1.1e-25	20	287
STKc_Cdc7_like	cd06627	2.7e-69	20	287
STKc_MAPKKK_Byr2_lik	cd06628	9.6e-42	20	287
STKc_MEKK1_plant	cd06632	4.3e-47	20	287
STKc_MEKK1	cd06630	1.6e-14	20	288
STKc_MEKK3	cd06651	4e-26	20	290
STKc_YSK4	cd06631	1.1e-32	20	287
STKc_CCRK	cd07832	3.8e-13	20	288
STKc_MAPK	cd07834	2.7e-12	20	325
STKc_Pho85	cd07836	1.3e-07	20	316
STKc_CDK5	cd07839	8.7e-10	20	287
STKc_CDK7	cd07841	2.2e-12	20	291
STKc_CDK8_like	cd07842	1.5e-08	20	287
STKc_NLK	cd07853	4.1e-07	20	381
STKc_MPK1	cd07857	2.7e-07	20	322
STKc_TDY_MAPK_plant	cd07859	4.6e-08	20	353
STKc_CDK2_3	cd07860	6.9e-07	20	301
STKc_CDK1_euk	cd07861	2.7e-08	20	316
STKc_CDK4	cd07863	1.5e-08	20	287
STKc_CDC2L6	cd07867	0.00057	20	306
STKc_CDK8	cd07868	0.00099	20	316
STKc_Nek2	cd08217	7.1e-18	20	287
STKc_Nek1	cd08218	5.8e-23	20	287
STKc_Nek3	cd08219	6.8e-20	20	287
STKc_Nek	cd08215	1.1e-40	20	287
STKc_Nek8	cd08220	5.3e-10	20	287
STKc_Nek9	cd08221	6.1e-10	20	287
STKc_Nek11	cd08222	1.1e-23	20	287
STKc_Nek4	cd08223	7.3e-16	20	287
STKc_Nek5	cd08225	5.4e-25	20	287
STKc_Nek10	cd08528	5.3e-12	20	284
STKc_FA2-like	cd08529	1.3e-20	20	287
STKc_CNK2-like	cd08530	1.5e-13	20	287
PTKc_Src_like	cd05034	9.6e-09	21	289
PTKc_Axl_like	cd05035	9.2e-07	21	288
PTKc_Csk_like	cd05039	7.6e-06	21	242
PTKc_Abl	cd05052	2.8e-07	21	290
PTKc_IGF-1R	cd05062	8.3e-05	21	289
PTKc_Frk_like	cd05068	1.2e-12	21	289
PTKc_Tyro3	cd05074	7.4e-06	21	289
PTKc_Axl	cd05075	0.00054	21	289
PTKc_Jak1_rpt2	cd05079	0.00099	21	290
PTKc_Tie1	cd05089	5.8e-06	21	308
STKc_CMGC	cd05118	9.5e-17	21	287
PTKc_Srm_Brk	cd05148	2.4e-05	21	287
STKc_PKN	cd05589	8.5e-09	21	335
STKc_CDK_like	cd07829	2.7e-19	21	287
STKc_MAK_like	cd07830	1.1e-13	21	287
STKc_MOK	cd07831	2e-13	21	287
STKc_CDK9_like	cd07840	8.2e-17	21	287
STKc_CDK4_6_like	cd07838	1.1e-13	21	287
STKc_CDK1_like	cd07835	2.5e-08	21	301
PTKc_Tyk2_rpt2	cd05080	9.2e-06	22	291
PTKc_Jak2_Jak3_rpt2	cd05081	2.3e-07	22	291
PK_STRAD_beta	cd08226	2.3e-07	22	302
PK_STRAD_alpha	cd08227	1.2e-07	22	380
PTKc_HER2	cd05109	1.3e-05	23	298
PTKc_HER4	cd05110	0.00013	23	315
PTKc_TrkC	cd05094	0.00042	23	323
STKc_RSK_N	cd05582	4.5e-07	24	349
STKc_p70S6K	cd05584	1.5e-10	24	353
PTKc	cd00192	1.2e-14	25	286
PTK_Jak_rpt1	cd05037	9.2e-07	25	282
PTKc_Ack_like	cd05040	3.2e-13	25	289
PTKc_Fes_like	cd05041	1.6e-11	25	287
PTKc_Aatyk	cd05042	5.9e-08	25	284
PTKc_Tie	cd05047	2.7e-05	25	289
PTKc_c-ros	cd05044	2.9e-06	25	284
PTKc_Met_Ron	cd05058	1.2e-06	25	293
PTKc_Syk_like	cd05060	3.5e-12	25	291
PTK_Tyk2_rpt1	cd05076	0.0003	25	286
PTK_Jak2_Jak3_rpt1	cd05078	1.6e-07	25	286
PTK_Jak1_rpt1	cd05077	4.3e-05	25	286
PTKc_Fes	cd05084	5.3e-09	25	287
PTKc_Fer	cd05085	5.3e-08	25	287
PTKc_Aatyk2	cd05086	1.5e-05	25	289
PTKc_Aatyk1_Aatyk3	cd05087	0.00017	25	286
PTKc_Syk	cd05116	8.4e-09	25	287
STKc_PKC	cd05570	1.8e-12	25	369
STKc_PKB	cd05571	2.5e-10	25	365
STKc_SGK	cd05575	2.9e-08	25	349
STKc_nPKC_epsilon	cd05591	7.3e-09	25	350
STKc_nPKC_theta_delt	cd05592	1.1e-09	25	353
STKc_PKB_gamma	cd05593	6.6e-08	25	365
STKc_PKB_alpha	cd05594	3.7e-09	25	355
STKc_PKB_beta	cd05595	1.8e-07	25	363
STKc_aPKC	cd05588	8.6e-09	25	350
STKc_SGK1	cd05602	1.5e-06	25	365
STKc_SGK2	cd05603	1.3e-08	25	364
STKc_aPKC_zeta	cd05617	4.7e-09	25	344
STKc_aPKC_iota	cd05618	2e-06	25	350
STKc_nPKC_theta	cd05619	1.7e-10	25	351
STKc_nPKC_delta	cd05620	4.6e-05	25	351
STKc_nPKC_eta	cd05590	8.2e-07	25	335
STKc_SGK3	cd05604	5.6e-06	25	361
STKc_MAPKKK_Bck1_lik	cd06629	1e-20	25	287
PTKc_Zap-70	cd05115	3.6e-08	26	290
STKc_beta_ARK	cd05606	1e-08	26	307
STKc_GRK3	cd05633	6e-09	26	308
PKc	cd00180	1.5e-71	27	285
STKc_AGC	cd05123	1.9e-21	27	287
STKc_cGK_PKG	cd05572	9.2e-13	27	294
STKc_GRK	cd05577	2e-10	27	307
STKc_YPK1_like	cd05585	1.4e-08	27	362
STKc_Sck1_like	cd05586	1.2e-08	27	410
STKc_MAST_like	cd05579	9.3e-17	27	292
STKc_GRK7	cd05607	5.7e-06	27	307
STKc_Rim15_like	cd05611	6.5e-06	27	342
STKc_GRK1	cd05608	9.6e-10	27	307
MYSc_type_IX	cd01385	1.8e-129	333	1056
MYSc_type_VI	cd01382	1.1e-53	335	1052
MYSc_type_VIII	cd01383	3.9e-123	337	1052
MYSc_type_XI	cd01384	1.4e-170	338	1056
MYSc_type_XV	cd01387	4.1e-169	338	1052
MYSc	cd00124		339	1052
MYSc_type_VII	cd01381	9.6e-211	339	1052
MYSc_type_V	cd01380	1.2e-139	339	1052
MYSc_type_XVIII	cd01386	4.2e-11	339	1052
MYSc_type_III	cd01379		339	1074
MYSc_type_I	cd01378	4.8e-145	340	1049
MYSc_type_II	cd01377	6.1e-121	340	1052
Motor_domain	cd01363	3.8e-18	374	891
Pkinase	pfam00069	2.9e-76	21	287
COG5022	COG5022	4.6e-89	269	1615
Myosin_head	pfam00063	2.1e-218	340	1041
IQ	pfam00612	0.00096	1083	1103
Pkinase_Tyr	pfam07714	3.1e-26	21	286
TyrKc	smart00219	2.4e-15	21	287
STYKc	smart00221	1.6e-79	21	287
S_TKc	smart00220	1.5e-88	31	287
KIND	smart00750	1.3e-32	106	295
MYSc	smart00242	1.7e-250	333	1053
IQ	smart00015	5.6e-05	1081	1103

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs33947968	Polymorphism	p.ALA833SER	N/A
Swiss-Prot	VAR_040878	Polymorphism	p.ALA1032THR	N/A
Swiss-Prot	VAR_040872	Polymorphism	p.ARG319HIS	N/A
Swiss-Prot	VAR_022779	Polymorphism	p.ARG1313SER	N/A
Swiss-Prot	VAR_040875	Polymorphism	p.ASN525LYS	N/A
Swiss-Prot	VAR_021866	Polymorphism	p.ASP204ASN	N/A
Swiss-Prot	VAR_040883	Polymorphism	p.ASP1347HIS	N/A
dbSNP	rs61729833	Polymorphism	p.GLU1010LYS	N/A
dbSNP	rs3824699	Polymorphism	p.ILE348VAL	N/A
Swiss-Prot	VAR_040885	Polymorphism	p.LYS1488GLU	N/A
Swiss-Prot	VAR_040882	Polymorphism	p.PRO1287THR	N/A
Swiss-Prot	VAR_040877	Polymorphism	p.SER956ARG	N/A
dbSNP	rs3758449	Polymorphism	p.SER956ASN	N/A
Swiss-Prot	VAR_040884	Polymorphism	p.THR1417ILE	N/A
Swiss-Prot	VAR_040871	Polymorphism	p.THR178ILE	N/A
Swiss-Prot	VAR_033905	Polymorphism	p.THR1284SER	N/A
Swiss-Prot	VAR_040881	Polymorphism	p.VAL1195ALA	N/A
Swiss-Prot	VAR_040874	Polymorphism	p.VAL369ILE	N/A
Swiss-Prot	VAR_040879	Polymorphism	p.VAL1045MET	N/A
Swiss-Prot	VAR_040880	Polymorphism	p.VAL1137MET	N/A
OMIM	606808.0001	Disease	p.TYR1043TER	DEAFNESS, AUTOSOMAL RECESSIVE 30

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258