Results for the protein: O60229

Results for the Protein: O60229

160380714

8997

KALRN

NCBI, UniProt

KALRN_HUMAN RecName: Full=Kalirin; AltName: Full=Huntingtin-associated protein-interacting protein; AltName: Full=Protein Duo; AltName: Full=Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain

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Swiss-Prot Protein: O60229

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
SPEC	cd00176	2.4e-16	311	536
SPEC	cd00176	2.2e-20	537	769
SPEC	cd00176	6.9e-19	891	1130
SPEC	cd00176	1.8e-08	1131	1373
RhoGEF	cd00160	3.7e-58	1282	1454
	cd01232	3.2e-64	1471	1581
	cd01222	7.8e-05	1472	1581
PH_Dbs	cd01227	4e-11	1473	1597
PH	cd00821	1e-07	1477	1578
PH-like	cd00900	0.00059	1477	1578
SH3	cd00174	2.8e-08	1650	1708
RhoGEF	cd00160	3.6e-52	1929	2101
	cd01232	1.4e-39	2118	2226
PH_Dbs	cd01227	1.1e-08	2120	2245
PH	cd00821	8.3e-05	2124	2223
Ig5_NCAM-1_like	cd05732	0.00023	2468	2564
Ig5_NCAM-1	cd05869	0.00078	2468	2564
Ig3_Contactin_like	cd04968	7.5e-06	2469	2565
Ig5_KIRREL3-like	cd05758	0.0009	2469	2563
Ig3_Contactin-1	cd05851	2e-08	2469	2565
Ig1_Robo	cd07693	0.00022	2469	2565
Ig1_NCAM-1_like	cd04977	0.00061	2471	2566
Ig_TrkABC_d4	cd04972	0.0003	2471	2566
Ig4_Contactin-2-like	cd05728	1.3e-05	2471	2564
Ig_M-protein_C	cd05891	0.00013	2471	2564
Ig3_NCAM-1_like	cd05730	0.0002	2474	2567
Ig_Myomesin_like_C	cd05737	0.0003	2476	2564
Ig2_Robo	cd05724	3.3e-06	2477	2564
Ig2_FGFRL1-like	cd05856	6.6e-06	2479	2564
Ig2_FGFR_like	cd05729	8.1e-07	2483	2564
Ig5_Contactin_like	cd04969	3e-08	2484	2564
Ig4_L1-NrCAM_like	cd04978	8.1e-06	2484	2565
Ig4_Robo	cd05726	0.00084	2484	2574
Ig3_Peroxidasin	cd05745	0.00014	2484	2564
Ig_Perlecan_D2_like	cd05743	0.00013	2484	2564
Ig_2	cd05764	4.4e-06	2484	2564
Ig5_Contactin-1	cd05852	5.9e-05	2484	2564
Ig4_L1-CAM_like	cd05867	0.00045	2484	2565
Ig_3	cd05765	1.7e-09	2484	2564
Ig4_Neogenin	cd05723	1.6e-06	2486	2564
Ig_Titin_like	cd05748	0.00014	2486	2564
Ig	cd00096	1.1e-10	2487	2561
Ig3_Robo	cd05725	1.5e-05	2487	2564
Ig3_L1-CAM_like	cd05731	0.001	2487	2565
Ig6_L1-CAM_like	cd05733	0.00076	2487	2565
Ig_Myotilin_C_like	cd05744	0.00077	2487	2564
Ig4_Peroxidasin	cd05746	4.1e-05	2487	2563
Ig2_PTK7	cd05760	0.00054	2487	2569
Ig_1	cd05763	4.5e-05	2487	2565
Ig_Palladin_C	cd05893	0.00092	2487	2564
Ig_Myotilin_C	cd05892	0.00046	2487	2564
FN3	cd00063	1.2e-21	2568	2661
STKc_ROCK1	cd05622	4.2e-06	2648	2982
STKc_ROCK	cd05596	1.6e-07	2649	2980
STKc_ROCK2	cd05621	6.2e-07	2656	2980
STKc_myosinIIIB	cd06639	1.2e-06	2658	2938
STKc_PAK6	cd06659	2.3e-11	2659	2954
STKc_PAK5	cd06658	1.7e-08	2660	2954
STKc_PAK	cd06614	1.6e-16	2662	2958
STKc_TAO1	cd06635	6.6e-06	2662	2969
STKc_PAK1	cd06654	9e-09	2662	2964
STKc_p38alpha_MAPK14	cd07877	8.3e-05	2662	2974
STKc_PAK_I	cd06647	3.4e-11	2663	2958
STKc_PAK_II	cd06648	2.1e-11	2663	2950
STKc_PAK2	cd06655	2.4e-09	2663	2961
STKc_PAK3	cd06656	1.4e-09	2663	2968
STKc_JNK	cd07850	2.2e-06	2663	2981
STKc_TAO3	cd06633	6.6e-05	2664	2984
STKc_p38beta_MAPK11	cd07878	0.00032	2664	2975
STKc_p38gamma_MAPK12	cd07880	1.9e-06	2664	2965
STKc_MAPKKK_Byr2_lik	cd06628	1.2e-15	2666	2937
STKc_MAP4K4_6	cd06636	1.8e-05	2666	2937
STKc_myosinIIIA	cd06638	5.3e-08	2666	2937
STKc_p38delta_MAPK13	cd07879	0.00027	2666	2972
STKc_JNK2	cd07876	6.2e-05	2666	2983
STKc_TAO	cd06607	7.3e-06	2667	2979
STKc_TAO2	cd06634	1.5e-06	2667	2985
STKc_CDK9	cd07865	1e-06	2669	2937
PKc_MKK7	cd06618	5.1e-07	2670	2960
STKc_STK10_LOK	cd06644	3.4e-06	2671	2957
STKc_p38	cd07851	9.2e-08	2671	2965
STKc_JNK3	cd07874	0.00063	2671	2983
PTKc_Abl	cd05052	5.3e-05	2675	2941
PTKc_Frk_like	cd05068	5.1e-06	2675	2940
PTKc_Hck	cd05073	0.00021	2675	2944
PTKc_Csk	cd05082	0.00062	2675	2935
PTKc_Lyn	cd05072	5.9e-05	2675	2935
PTKc_Lck_Blk	cd05067	0.00054	2675	2957
PTKc_Srm_Brk	cd05148	2.6e-05	2675	2952
STKc_MAP4K5	cd06646	4.6e-06	2675	2936
STKc_CDK12	cd07864	4.4e-07	2675	2937
PTKc_ALK_LTK	cd05036	3.5e-05	2676	2920
STKc_MAP4K3	cd06645	4.9e-07	2676	2936
STKc_PAK4	cd06657	6.7e-08	2676	2955
PTKc_FAK	cd05056	2.6e-05	2677	2941
PTKc_EphR_A2	cd05063	0.00039	2677	2937
STKc_NDR_like	cd05599	1.2e-08	2677	2982
STKc_PDK1	cd05581	2.4e-19	2677	2937
STKc_NDR2	cd05627	1.8e-05	2677	2982
STKc_NDR1	cd05628	3.4e-07	2677	2982
STKc_ASK	cd06624	7.4e-13	2677	2937
PKc_MAPKK_plant_like	cd06623	7.4e-16	2677	2942
STKc_SLK	cd06643	1.7e-06	2677	2955
PKc_MEK2	cd06649	0.00026	2677	2985
STKc_SLK_like	cd06611	1.3e-07	2677	2952
STKc_ERK1_2_like	cd07849	2e-07	2677	2983
STKc_MAPK15	cd07852	4.3e-06	2677	2981
STKc_ERK5	cd07855	1.3e-06	2677	2980
PTKc_EphR_A10	cd05064	0.00037	2678	2941
STKc_MSK_N	cd05583	2.2e-09	2678	2960
STKc_MSK1_N	cd05613	1.2e-08	2678	2953
STKc_STK25-YSK1	cd06642	4.7e-10	2678	2965
STKc_MST4	cd06640	3.9e-08	2678	2965
STKc_MST3	cd06641	5.9e-08	2678	2965
STKc_TNIK	cd06637	9.9e-07	2678	2937
STKc_CDC2L1	cd07843	0.00042	2678	2937
STKc_BUR1	cd07866	8.8e-05	2678	2937
STKc_TEY_MAPK_plant	cd07858	6.4e-07	2678	2980
PTKc_Jak_rpt2	cd05038	0.00013	2679	2938
PTKc_EphR	cd05033	0.00021	2679	2936
PTKc_EphR_B	cd05065	0.00023	2679	2937
PTKc_Jak2_Jak3_rpt2	cd05081	0.00039	2679	2962
STKc_MAP4K3_like	cd06613	4.1e-11	2679	2936
PKc_MKK4	cd06616	1.3e-05	2679	2959
STKc_MAPK4_6	cd07854	6.1e-06	2679	2981
STKc_Sty1_Hog1	cd07856	6.6e-08	2679	2959
STKc_PFTAIRE1	cd07869	8.5e-05	2679	2946
STKc_PFTAIRE2	cd07870	1.5e-07	2679	2937
PTKc_Btk_Bmx	cd05113	4.3e-07	2680	2936
PKc_MAPKK_Byr1_like	cd06620	0.0005	2680	2955
STKc_MEKK2	cd06652	1.5e-06	2680	2938
STKc_MEKK3_like_1	cd06653	6.4e-08	2680	2937
PTKc_Tec_like	cd05059	3.6e-05	2681	2936
PTKc_Itk	cd05112	1.4e-07	2681	2936
PTKc_Tec_Rlk	cd05114	6e-07	2681	2936
STKc_phototropin_lik	cd05574	3.2e-12	2681	2944
STKc_ROCK_NDR_like	cd05573	4.9e-12	2681	2979
STKc_PKA	cd05580	8.4e-14	2681	2973
STKc_Sid2p_Dbf2p	cd05600	0.00012	2681	2980
STKc_DMPK_like	cd05597	4.7e-07	2681	2985
STKc_PRKX_like	cd05612	1.9e-10	2681	2977
STKc_MAST	cd05609	2.8e-09	2681	2985
STKc_LATS	cd05598	1e-07	2681	2984
STKc_MRCK_beta	cd05624	7.7e-07	2681	2978
STKc_NDR_like_fungal	cd05629	0.00024	2681	2982
STKc_MRCK_alpha	cd05623	2.2e-07	2681	2978
STKc_MST3_like	cd06609	5.1e-12	2681	2958
STKc_OSR1_SPAK	cd06610	2.7e-10	2681	2937
PKc_MEK	cd06615	3.3e-06	2681	2977
PKc_MAPKK_Pek1_like	cd06621	8.9e-07	2681	2948
PKc_MAPKK_PBS2_like	cd06622	2e-07	2681	2984
PKc_MKK5	cd06619	0.0001	2681	2961
PKc_MKK3_6	cd06617	5.6e-07	2681	2956
PKc_MAPKK	cd06605	1e-08	2681	2942
STKc_NAK1_like	cd06917	7e-10	2681	2962
STKc_CDKL	cd07833	2.7e-08	2681	2937
STKc_CdkB_plant	cd07837	1.9e-08	2681	2938
STKc_PCTAIRE_like	cd07844	3.1e-09	2681	2973
STKc_CDK10	cd07845	2.9e-07	2681	2958
STKc_CDKL2_3	cd07846	3.5e-08	2681	2937
STKc_CDKL1_4	cd07847	2.9e-08	2681	2954
STKc_CDKL5	cd07848	0.00019	2681	2937
STKc_PCTAIRE3	cd07871	1.8e-07	2681	2937
STKc_PCTAIRE2	cd07872	1.4e-06	2681	2957
STKc_PCTAIRE1	cd07873	2.9e-06	2681	2949
STKc_Nek7	cd08229	1.1e-09	2681	2941
STKc_Nek6	cd08228	9.7e-09	2681	2941
STKc_Nek6_Nek7	cd08224	4.6e-11	2681	2941
SPS1	COG0515	1.6e-33	2681	2983
PKc_STE	cd05122	2.1e-22	2682	2936
STKc_Yank1	cd05578	1.2e-13	2682	2937
STKc_cPKC	cd05587	2.1e-05	2682	2982
STKc_GRK4_like	cd05605	4.1e-16	2682	2967
STKc_cPKC_alpha	cd05615	6.6e-05	2682	2978
STKc_cPKC_beta	cd05616	0.0003	2682	2982
STKc_MSK2_N	cd05614	1.5e-08	2682	2984
STKc_GRK6	cd05630	9.5e-09	2682	2967
STKc_GRK4	cd05631	9.2e-09	2682	2967
STKc_GRK5	cd05632	3.1e-09	2682	2967
STKc_MAPKKK	cd06606	1.7e-21	2682	2937
STKc_myosinIII_like	cd06608	8.4e-10	2682	2937
STKc_YSK4	cd06631	6.4e-09	2682	2937
STKc_MEKK3	cd06651	1.7e-09	2682	2939
STKc_MEKK1	cd06630	3.5e-08	2682	2938
STKc_Cdc7_like	cd06627	2.4e-18	2682	2937
STKc_MAPK	cd07834	1.3e-09	2682	2980
STKc_Pho85	cd07836	5.9e-06	2682	2973
STKc_CCRK	cd07832	2.9e-11	2682	2938
STKc_CDK7	cd07841	2.2e-09	2682	2948
STKc_CDK5	cd07839	8.2e-06	2682	2937
STKc_MPK1	cd07857	1.4e-05	2682	2981
STKc_TDY_MAPK_plant	cd07859	2.9e-06	2682	2978
STKc_CDK2_3	cd07860	1.1e-06	2682	2937
STKc_CDK1_euk	cd07861	6.6e-08	2682	2937
STKc_CDK4	cd07863	1e-05	2682	2937
STKc_Nek	cd08215	1.9e-15	2682	2937
STKc_Nek2	cd08217	6.8e-11	2682	2937
STKc_Nek3	cd08219	2.5e-11	2682	2937
STKc_Nek8	cd08220	2.2e-08	2682	2937
STKc_Nek9	cd08221	3.8e-07	2682	2937
STKc_Nek1	cd08218	2.3e-06	2682	2937
STKc_Nek11	cd08222	4.1e-06	2682	2937
STKc_Nek5	cd08225	2.6e-09	2682	2937
STKc_Nek4	cd08223	2.5e-06	2682	2937
STKc_FA2-like	cd08529	3e-09	2682	2937
STKc_Nek10	cd08528	0.00011	2682	2933
STKc_CMGC	cd05118	1.5e-12	2683	2937
STKc_p70S6K	cd05584	5e-08	2683	2984
STKc_PKN	cd05589	4.7e-06	2683	2977
STKc_CDK_like	cd07829	8.4e-13	2683	2937
STKc_MOK	cd07831	3.5e-10	2683	2937
STKc_CDK1_like	cd07835	5.9e-08	2683	2937
STKc_MAK_like	cd07830	1.3e-10	2683	2937
STKc_CDK4_6_like	cd07838	1.9e-08	2683	2937
STKc_CDK9_like	cd07840	5e-10	2683	2937
PK_STRAD	cd08216	0.00049	2684	2939
STKc_MST1_2	cd06612	3.5e-12	2685	2937
STKc_RSK_N	cd05582	1.1e-06	2686	2977
STKc_Rim15_like	cd05611	0.00016	2686	2950
STKc_MEKK4	cd06626	4e-10	2686	2937
PTKc	cd00192	4.4e-08	2687	2936
PTKc_Ack_like	cd05040	1.2e-05	2687	2905
PTKc_Fes_like	cd05041	3.7e-05	2687	2939
PTKc_Fes	cd05084	0.00063	2687	2937
PTKc_Syk	cd05116	5.9e-05	2687	2937
STKc_SGK	cd05575	1.8e-07	2687	2985
STKc_PKB	cd05571	3.2e-09	2687	2979
STKc_nPKC_eta	cd05590	6e-05	2687	2978
STKc_PKB_gamma	cd05593	2e-06	2687	2982
STKc_nPKC_theta_delt	cd05592	7.4e-07	2687	2985
STKc_aPKC	cd05588	4.3e-07	2687	2985
STKc_PKB_alpha	cd05594	2.2e-07	2687	2980
STKc_PKB_beta	cd05595	1.7e-06	2687	2979
STKc_nPKC_epsilon	cd05591	1e-05	2687	2984
STKc_CRIK	cd05601	6.6e-10	2687	2977
STKc_SGK2	cd05603	5.2e-09	2687	2978
STKc_nPKC_delta	cd05620	0.00083	2687	2983
STKc_SGK3	cd05604	1.4e-05	2687	2985
STKc_nPKC_theta	cd05619	4.6e-07	2687	2983
PTKc_Src_like	cd05034	2.2e-06	2688	2940
PTKc_Zap-70	cd05115	0.00016	2688	2915
PKc	cd00180	4.1e-61	2689	2935
STKc_AGC	cd05123	2.2e-17	2689	2937
STKc_cGK_PKG	cd05572	4.6e-13	2689	2944
STKc_PKC	cd05570	6.6e-07	2689	2985
STKc_GRK	cd05577	3.6e-13	2689	2949
STKc_YPK1_like	cd05585	1.5e-08	2689	2983
STKc_SGK1	cd05602	4.6e-07	2689	2979
STKc_Sck1_like	cd05586	3.8e-05	2689	2984
STKc_MAST_like	cd05579	1.2e-14	2689	2942
STKc_GRK7	cd05607	7.4e-08	2689	2961
STKc_GRK1	cd05608	4.2e-11	2689	2975
STKc_aPKC_zeta	cd05617	1.2e-05	2689	2982
STKc_aPKC_iota	cd05618	5.5e-05	2689	2982
STKc_beta_ARK	cd05606	1.2e-08	2689	2957
STKc_GRK3	cd05633	1.5e-07	2689	2960
STKc_MEKK3_like	cd06625	3.1e-12	2689	2937
STKc_MAPKKK_Bck1_lik	cd06629	1.5e-07	2689	2937
STKc_MEKK1_plant	cd06632	8.4e-11	2689	2937
STKc_CNK2-like	cd08530	8.2e-08	2693	2937
Spectrin	pfam00435	2.1e-05	310	416
Spectrin	pfam00435	0.0003	536	642
Spectrin	pfam00435	1.6e-05	1130	1236
RhoGEF	pfam00621	4.4e-49	1286	1455
PH	pfam00169	2e-10	1469	1580
SH3_1	pfam00018	0.0001	1652	1703
RhoGEF	pfam00621	6e-53	1933	2102
PH	pfam00169	0.00086	2122	2225
ig	pfam00047	3.4e-07	2484	2549
fn3	pfam00041	2.3e-13	2569	2653
Pkinase	pfam00069	2e-66	2683	2937
SEC14	smart00516	4.1e-26	38	177
SPEC	smart00150	3.4e-12	191	307
SPEC	smart00150	3.5e-12	313	415
SPEC	smart00150	1.2e-15	539	641
SPEC	smart00150	0.00063	644	766
SPEC	smart00150	5.4e-10	893	1003
SPEC	smart00150	5e-11	1133	1235
RhoGEF	smart00325	6.3e-58	1285	1455
PH	smart00233	6.4e-09	1475	1580
SH3	smart00326	2.5e-07	1647	1709
RhoGEF	smart00325	3.6e-49	1932	2102
PH	smart00233	0.00029	2116	2225
I-set	pfam07679	5.1e-22	2470	2564
IG_like	smart00410	6.6e-14	2476	2565
IG	smart00409	6.6e-14	2476	2565
IGc2	smart00408	2.2e-11	2483	2554
FN3	smart00060	1e-16	2568	2650
Pkinase_Tyr	pfam07714	1.2e-09	2683	2935
STYKc	smart00221	3.4e-65	2683	2937
TyrKc	smart00219	1.2e-08	2683	2937
S_TKc	smart00220	4.1e-68	2693	2937

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_057190	Polymorphism	p.ARG1929MET	N/A
Swiss-Prot	VAR_035976	Polymorphism	p.ARG213TRP	N/A
Swiss-Prot	VAR_020192	Polymorphism	p.GLU1326ASP	N/A
Swiss-Prot	VAR_035625	Polymorphism	p.SER1896CYS	N/A
Swiss-Prot	VAR_041898	Polymorphism	p.SER196LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258