Results for the protein: P51955

Results for the Protein: P51955

1709252

4751

NEK2

NCBI, UniProt

NEK2_HUMAN RecName: Full=Serine/threonine-protein kinase Nek2; AltName: Full=HSPK 21; AltName: Full=Never in mitosis A-related kinase 2; Short=NimA-related protein kinase 2; AltName: Full=NimA-like protein kinase 1

			0 2 0 0 2

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Swiss-Prot Protein: P51955

Identical to: NP_002488

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_PDGFR	cd05055	4.5e-05	1	275
PTKc_FAK	cd05056	3.7e-10	1	279
PTKc_IGF-1R	cd05062	1.4e-06	1	273
PTKc_EphR_A2	cd05063	3.4e-05	1	275
PTKc_InsR	cd05061	3.8e-06	1	283
PTKc_FGFR	cd05053	1.6e-06	1	275
PTKc_Yes	cd05069	7e-07	1	269
PTKc_Src	cd05071	1.2e-05	1	271
PTKc_Tie2	cd05088	6.7e-07	1	290
PTKc_Ror1	cd05090	0.00021	1	273
PTKc_FGFR1	cd05098	0.00032	1	280
PTKc_FGFR4	cd05099	7e-06	1	293
PTKc_FGFR3	cd05100	0.00042	1	309
PTKc_HER2	cd05109	3.1e-05	1	285
STKc_ROCK2	cd05621	6.4e-06	1	317
STKc_ROCK1	cd05622	1.1e-05	1	316
STKc_ROCK	cd05596	2e-05	1	317
STKc_myosinIII_like	cd06608	1e-15	1	271
STKc_TAO1	cd06635	3.3e-08	1	314
STKc_MAP4K4_6	cd06636	1.6e-12	1	271
STKc_myosinIIIA	cd06638	3.6e-13	1	271
STKc_myosinIIIB	cd06639	1e-14	1	272
STKc_TNIK	cd06637	5.4e-16	1	271
STKc_PAK6	cd06659	5.1e-11	1	294
STKc_JNK	cd07850	9.6e-07	1	363
STKc_JNK1	cd07875	7.9e-05	1	315
STKc_p38alpha_MAPK14	cd07877	2.3e-06	1	329
STKc_p38beta_MAPK11	cd07878	1.1e-06	1	331
STKc_p38gamma_MAPK12	cd07880	6.7e-07	1	350
PTKc_ALK_LTK	cd05036	4.2e-08	2	273
PTK_Ryk	cd05043	8.8e-06	2	261
PTKc_Ror	cd05048	3.1e-06	2	254
PKc_MKK7	cd06618	4.3e-10	2	285
STKc_TAO	cd06607	8.8e-10	2	314
STKc_TAO3	cd06633	1.4e-06	2	314
STKc_TAO2	cd06634	5.4e-10	2	315
STKc_PAK4	cd06657	4.1e-09	2	290
PTKc_EGFR_like	cd05057	1.9e-05	3	285
PTKc_FGFR2	cd05101	1.2e-05	3	279
STKc_SLK	cd06643	6.9e-12	3	289
STKc_STK10_LOK	cd06644	3.7e-11	3	291
STKc_MAP4K3	cd06645	1.7e-10	3	270
STKc_MAP4K5	cd06646	4.8e-10	3	270
STKc_PAK1	cd06654	9.8e-10	3	283
STKc_PCTAIRE_like	cd07844	4.2e-16	3	308
STKc_CDK10	cd07845	8e-11	3	273
STKc_TEY_MAPK_plant	cd07858	4.2e-09	3	321
STKc_CDK12	cd07864	4.9e-13	3	271
STKc_CDK9	cd07865	3e-10	3	271
STKc_BUR1	cd07866	3e-07	3	271
STKc_PFTAIRE1	cd07869	2.2e-05	3	292
STKc_PFTAIRE2	cd07870	1.2e-07	3	271
STKc_PCTAIRE2	cd07872	2.4e-08	3	307
STKc_PCTAIRE1	cd07873	3.8e-08	3	285
STKc_JNK3	cd07874	2.1e-05	3	333
STKc_JNK2	cd07876	4.5e-06	3	333
STKc_p38delta_MAPK13	cd07879	0.00028	3	324
STKc_PCTAIRE3	cd07871	1.5e-09	3	290
PTKc_Trk	cd05049	5e-08	4	268
PTKc_Abl	cd05052	3.5e-10	4	275
PTKc_EphR_A	cd05066	6.9e-06	4	275
PTKc_Frk_like	cd05068	2.3e-10	4	269
PTKc_Fyn_Yrk	cd05070	6e-06	4	269
PTKc_Lyn	cd05072	7.1e-09	4	274
PTKc_Jak1_rpt2	cd05079	2.6e-05	4	271
PTKc_Jak2_Jak3_rpt2	cd05081	4.4e-07	4	275
PTKc_Csk	cd05082	4.8e-07	4	274
PTKc_Chk	cd05083	1.7e-05	4	273
PTKc_InsR_like	cd05032	1.6e-07	4	273
PTKc_TrkB	cd05093	3.2e-05	4	278
PTKc_TrkC	cd05094	0.00033	4	314
PTKc_VEGFR3	cd05102	2.2e-05	4	278
PTKc_EGFR	cd05108	5.2e-06	4	328
PTKc_TrkA	cd05092	2.3e-06	4	276
PTK_HER3	cd05111	4.9e-05	4	285
PTKc_Itk	cd05112	7e-09	4	270
PTKc_Btk_Bmx	cd05113	1.3e-11	4	270
PTKc_Tec_Rlk	cd05114	1.9e-08	4	270
STKc_GRK6	cd05630	5.5e-06	4	299
STKc_GRK4	cd05631	3.2e-06	4	299
STKc_GRK5	cd05632	2.7e-06	4	299
STKc_MAP4K3_like	cd06613	1.3e-17	4	270
STKc_PAK	cd06614	3.3e-21	4	275
PKc_MKK4	cd06616	1.3e-10	4	290
STKc_ASK	cd06624	1.7e-19	4	271
PKc_MAPKK_Byr1_like	cd06620	7.7e-11	4	276
STKc_PAK_II	cd06648	1.7e-13	4	284
PKc_MEK2	cd06649	1.4e-07	4	334
PKc_MEK1	cd06650	3.4e-06	4	319
STKc_PAK2	cd06655	1.4e-09	4	284
STKc_PAK5	cd06658	8.5e-09	4	288
STKc_ERK5	cd07855	9.7e-09	4	309
PTKc_Csk_like	cd05039	5.9e-05	5	269
PTKc_EphR	cd05033	5.1e-05	5	271
PTKc_Tec_like	cd05059	3.1e-10	5	270
PTKc_EphR_A10	cd05064	4.6e-05	5	275
PTKc_EphR_B	cd05065	6.6e-05	5	271
PTKc_Lck_Blk	cd05067	1.1e-06	5	269
PTKc_Hck	cd05073	2.5e-08	5	274
PTKc_VEGFR2	cd05103	9.5e-05	5	278
STKc_SLK_like	cd06611	3.5e-15	5	277
STKc_MEKK2	cd06652	6.7e-13	5	272
STKc_MEKK3_like_1	cd06653	3e-12	5	271
STKc_ERK1_2_like	cd07849	1e-09	5	318
STKc_MAPK15	cd07852	9e-13	5	293
STKc_Sty1_Hog1	cd07856	1e-07	5	295
STKc_Nek6_Nek7	cd08224	1.1e-59	5	277
STKc_Nek6	cd08228	3.9e-46	5	274
STKc_Nek7	cd08229	2.5e-42	5	276
PTKc_Src_like	cd05034	7.8e-09	6	269
PTKc_Jak_rpt2	cd05038	1.3e-07	6	276
PTKc_Musk	cd05050	1.8e-07	6	268
PTKc_Tie1	cd05089	5.9e-07	6	289
PTKc_Srm_Brk	cd05148	3.2e-07	6	269
STKc_ROCK_NDR_like	cd05573	1.4e-12	6	309
STKc_phototropin_lik	cd05574	1.8e-07	6	279
STKc_PKA	cd05580	7.4e-15	6	286
STKc_PDK1	cd05581	3.9e-20	6	271
STKc_DMPK_like	cd05597	4.5e-09	6	335
STKc_LATS	cd05598	1.2e-08	6	340
STKc_NDR_like	cd05599	3.6e-09	6	325
STKc_Sid2p_Dbf2p	cd05600	5e-08	6	338
STKc_MAST	cd05609	6.1e-08	6	323
STKc_CRIK	cd05601	3.4e-10	6	311
STKc_PRKX_like	cd05612	5.8e-11	6	287
STKc_MRCK_alpha	cd05623	8.9e-09	6	341
STKc_LATS2	cd05626	2.6e-05	6	340
STKc_NDR1	cd05628	6.7e-10	6	341
STKc_NDR_like_fungal	cd05629	4.1e-07	6	349
STKc_NDR2	cd05627	6.1e-08	6	361
STKc_MRCK_beta	cd05624	1.6e-08	6	316
PKc_MAPKK	cd06605	1e-17	6	276
STKc_MST3_like	cd06609	2.9e-19	6	291
STKc_OSR1_SPAK	cd06610	2.6e-16	6	271
STKc_MST1_2	cd06612	9.1e-21	6	271
PKc_MEK	cd06615	1.4e-11	6	291
PKc_MKK3_6	cd06617	6.9e-12	6	288
PKc_MKK5	cd06619	2.4e-06	6	287
PKc_MAPKK_PBS2_like	cd06622	1.5e-12	6	323
PKc_MAPKK_plant_like	cd06623	5.1e-20	6	274
PKc_MAPKK_Pek1_like	cd06621	3.1e-14	6	291
STKc_NAK1_like	cd06917	5.6e-16	6	279
STKc_CdkB_plant	cd07837	1.5e-12	6	272
STKc_CDKL	cd07833	1.7e-11	6	271
STKc_CDC2L1	cd07843	1.3e-10	6	271
STKc_CDKL2_3	cd07846	1.6e-10	6	271
STKc_CDKL1_4	cd07847	1.2e-25	6	308
STKc_CDKL5	cd07848	2.5e-06	6	271
STKc_p38	cd07851	4.9e-11	6	316
STKc_CDK6	cd07862	1.7e-08	6	308
SPS1	COG0515	5.5e-60	6	437
PTKc_RET	cd05045	4.5e-06	7	273
PKc_STE	cd05122	1e-43	7	270
STKc_Yank1	cd05578	6.1e-16	7	271
STKc_MSK_N	cd05583	1.1e-11	7	293
STKc_cPKC	cd05587	3.5e-08	7	336
STKc_GRK4_like	cd05605	1.4e-09	7	299
STKc_MSK1_N	cd05613	4.9e-08	7	285
STKc_MSK2_N	cd05614	1.1e-07	7	336
STKc_cPKC_alpha	cd05615	7.3e-08	7	323
STKc_cPKC_beta	cd05616	4.8e-07	7	339
STKc_MAPKKK	cd06606	4.1e-42	7	271
STKc_Cdc7_like	cd06627	9.5e-20	7	271
STKc_MAPKKK_Byr2_lik	cd06628	5e-28	7	271
STKc_MST3	cd06641	1.7e-13	7	282
STKc_STK25-YSK1	cd06642	8.6e-12	7	282
STKc_PAK_I	cd06647	1.1e-12	7	292
STKc_MEKK3	cd06651	5.6e-17	7	274
STKc_MST4	cd06640	1e-09	7	282
STKc_PAK3	cd06656	2.6e-10	7	285
STKc_CCRK	cd07832	2.3e-13	7	272
STKc_MAPK	cd07834	1.3e-12	7	315
STKc_Pho85	cd07836	2.9e-22	7	308
STKc_CDK5	cd07839	4.1e-11	7	308
STKc_CDK7	cd07841	2.9e-14	7	275
STKc_CDK8_like	cd07842	4.1e-11	7	271
STKc_NLK	cd07853	1.7e-08	7	346
STKc_MPK1	cd07857	1.1e-09	7	311
STKc_TDY_MAPK_plant	cd07859	3.8e-10	7	317
STKc_CDK1_euk	cd07861	1.8e-18	7	308
STKc_CDK2_3	cd07860	2.5e-14	7	271
STKc_CDK4	cd07863	6.8e-09	7	293
STKc_CDC2L6	cd07867	5.6e-07	7	328
STKc_CDK8	cd07868	1.5e-06	7	328
STKc_Nek	cd08215	8.9e-152	7	271
STKc_Nek2	cd08217	3.2e-208	7	271
STKc_Nek1	cd08218	3.3e-75	7	271
STKc_Nek3	cd08219	4.5e-70	7	271
STKc_Nek8	cd08220	3.4e-68	7	271
STKc_Nek9	cd08221	2.7e-74	7	271
STKc_Nek11	cd08222	2.1e-56	7	271
STKc_Nek4	cd08223	1.5e-65	7	271
STKc_Nek5	cd08225	6.5e-72	7	271
STKc_Nek10	cd08528	6.6e-41	7	273
STKc_FA2-like	cd08529	1.5e-68	7	271
STKc_CNK2-like	cd08530	6.6e-68	7	271
PTKc_Axl_like	cd05035	1.3e-05	8	270
PTKc_Tyro3	cd05074	0.00042	8	270
PTKc_Axl	cd05075	3.3e-05	8	270
STKc_CMGC	cd05118	2.1e-18	8	271
STKc_PKN	cd05589	9.2e-08	8	341
STKc_LATS1	cd05625	9.9e-06	8	340
STKc_CDK_like	cd07829	2.7e-21	8	271
STKc_MAK_like	cd07830	1.7e-14	8	271
STKc_MOK	cd07831	1.4e-13	8	271
STKc_CDK1_like	cd07835	1.1e-18	8	308
STKc_CDK4_6_like	cd07838	8.5e-14	8	271
STKc_CDK9_like	cd07840	2.6e-16	8	271
STKc_MAPK4_6	cd07854	2.8e-09	8	316
PTKc_Tyk2_rpt2	cd05080	0.00015	9	277
PK_STRAD	cd08216	0.00011	9	277
PK_STRAD_alpha	cd08227	0.00037	9	376
STKc_p70S6K	cd05584	1.9e-12	11	336
STKc_Rim15_like	cd05611	4.9e-07	11	277
STKc_RSK_N	cd05582	2.1e-08	11	334
STKc_MEKK4	cd06626	2.2e-16	11	271
STKc_YSK4	cd06631	7.7e-14	11	271
PTKc	cd00192	1.6e-14	12	270
PTKc_Ack_like	cd05040	8.6e-09	12	267
PTKc_Fes_like	cd05041	7.2e-09	12	271
PTKc_Met_Ron	cd05058	2.9e-05	12	277
PTKc_Syk_like	cd05060	1.1e-06	12	271
PTKc_Aatyk2	cd05086	3.1e-06	12	273
PTKc_Aatyk1_Aatyk3	cd05087	2.9e-05	12	270
PTKc_Syk	cd05116	2.4e-08	12	271
PTKc_Zap-70	cd05115	3.4e-07	12	274
STKc_PKC	cd05570	1.9e-11	12	334
STKc_PKB	cd05571	8.5e-10	12	343
STKc_SGK	cd05575	4.3e-08	12	336
STKc_aPKC	cd05588	4.1e-09	12	350
STKc_nPKC_eta	cd05590	1e-07	12	336
STKc_nPKC_epsilon	cd05591	1.5e-09	12	336
STKc_nPKC_theta_delt	cd05592	3.6e-10	12	343
STKc_PKB_gamma	cd05593	4.1e-06	12	338
STKc_PKB_alpha	cd05594	2.2e-08	12	346
STKc_PKB_beta	cd05595	1.3e-06	12	348
STKc_SGK1	cd05602	5.8e-07	12	321
STKc_SGK3	cd05604	1e-05	12	328
STKc_SGK2	cd05603	1.1e-08	12	333
STKc_aPKC_zeta	cd05617	3.7e-07	12	350
STKc_aPKC_iota	cd05618	1.1e-06	12	336
STKc_nPKC_theta	cd05619	1.7e-08	12	343
STKc_nPKC_delta	cd05620	3.6e-05	12	343
PTKc_Tie	cd05047	9e-07	13	275
PTKc_Fes	cd05084	1.4e-08	13	272
STKc_beta_ARK	cd05606	8.8e-08	13	293
STKc_GRK3	cd05633	4.2e-06	13	294
STKc_MEKK3_like	cd06625	2.1e-22	13	271
STKc_MEKK1	cd06630	6.1e-11	13	272
PKc	cd00180	1e-85	14	269
PTKc_Aatyk	cd05042	3.2e-07	14	273
PTKc_c-ros	cd05044	2.7e-08	14	268
PTKc_Fer	cd05085	4e-08	14	271
STKc_AGC	cd05123	4.5e-20	14	271
STKc_cGK_PKG	cd05572	1.2e-15	14	278
STKc_MAST_like	cd05579	2.4e-18	14	276
STKc_YPK1_like	cd05585	9.4e-10	14	336
STKc_Sck1_like	cd05586	2.6e-09	14	380
STKc_GRK7	cd05607	3.7e-08	14	298
STKc_GRK1	cd05608	2.4e-10	14	305
STKc_GRK	cd05577	2.3e-10	14	298
STKc_MAPKKK_Bck1_lik	cd06629	3.1e-11	14	271
STKc_MEKK1_plant	cd06632	2.8e-18	14	271
Pkinase	pfam00069	2.6e-69	8	271
Pkinase_Tyr	pfam07714	3.7e-16	8	269
TyrKc	smart00219	7.7e-15	8	269
STYKc	smart00221	5e-83	8	271
S_TKc	smart00220	2.3e-94	18	271
KIND	smart00750	4.9e-06	92	327

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_019990	Polymorphism	p.ASN354SER	N/A
Swiss-Prot	VAR_040907	Polymorphism	p.CYS410TYR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258