Results for the protein: Q06418

Results for the Protein: Q06418

1717829

7301

TYRO3

NCBI, UniProt

TYRO3_HUMAN RecName: Full=Tyrosine-protein kinase receptor TYRO3; AltName: Full=Tyrosine-protein kinase BYK; AltName: Full=Tyrosine-protein kinase DTK; AltName: Full=Tyrosine-protein kinase RSE; AltName: Full=Tyrosine-protein kinase SKY; AltName: Full=Tyrosine-protein kinase TIF; Flags: Precursor

			0 8 0 3 5

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Swiss-Prot Protein: Q06418

Identical to: NP_006284

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Ig2_Robo	cd05724	5.4e-05	47	135
Ig1_Neogenin	cd05722	0.00074	49	135
Ig2_FGFR_like	cd05729	3.5e-05	51	135
Ig2_FGFR	cd05857	7.1e-05	52	135
Ig	cd00096	8.2e-11	60	132
Ig1_Robo	cd07693	7e-06	138	222
Ig2_Tyro3_like	cd05749	2.5e-57	141	220
Ig	cd00096	0.00011	156	218
FN3	cd00063	1.2e-16	225	317
FN3	cd00063	7.3e-05	322	413
PTKc_Kit	cd05104	3.9e-14	384	790
PTKc_VEGFR	cd05054	7.4e-32	413	793
PTKc_CSF-1R	cd05106	1e-21	470	791
PTKc_PDGFR_alpha	cd05105	4.9e-16	474	792
PTKc_PDGFR_beta	cd05107	1.1e-10	474	791
PTKc_PDGFR	cd05055	4.2e-18	475	790
STKc_myosinIIIB	cd06639	6.7e-06	495	790
PKc_MKK7	cd06618	0.00018	497	792
PTKc_FGFR1	cd05098	4e-53	499	801
STKc_myosinIIIA	cd06638	8.1e-06	500	789
STKc_PAK6	cd06659	7.7e-05	500	815
STKc_p38	cd07851	0.00071	500	812
PTK_Tyk2_rpt1	cd05076	2.5e-05	501	787
PTKc_FGFR2	cd05101	6.5e-49	501	801
STKc_PAK	cd06614	7.7e-09	501	794
STKc_PAK_I	cd06647	0.00022	501	812
STKc_PAK_II	cd06648	5.9e-05	501	800
STKc_PAK1	cd06654	0.00013	501	814
STKc_PAK2	cd06655	0.00045	501	815
STKc_PAK3	cd06656	9.2e-05	501	816
PTKc_FGFR4	cd05099	1.2e-55	504	803
STKc_STK10_LOK	cd06644	5.3e-06	505	812
STKc_CDK9	cd07865	6.7e-06	506	779
PTKc_FGFR	cd05053	8.9e-64	509	791
PTKc_EGFR_like	cd05057	1.9e-62	510	808
PTKc_VEGFR3	cd05102	1.5e-35	510	793
PTK_HER3	cd05111	5.3e-40	510	808
PTKc_ALK_LTK	cd05036	8.4e-70	511	788
PTK_Ryk	cd05043	1.7e-48	511	793
PTKc_Csk_like	cd05039	4.2e-34	511	789
PTKc_FAK	cd05056	3e-74	511	794
PTKc_Chk	cd05083	5.8e-56	511	789
STKc_TNIK	cd06637	0.00043	511	789
STKc_TEY_MAPK_plant	cd07858	0.00012	511	847
PTK_CCK4	cd05046	8.8e-35	512	788
PTKc_Trk	cd05049	7.9e-57	512	795
PTKc_DDR	cd05051	5.3e-50	512	788
PTKc_Ror	cd05048	5.1e-44	512	789
PTKc_Tie2	cd05088	4.8e-45	512	820
PTKc_EGFR	cd05108	5.2e-48	512	822
PTKc_HER2	cd05109	8.3e-44	512	800
PTKc_HER4	cd05110	4.1e-39	512	812
STKc_SLK_like	cd06611	2.8e-07	512	799
STKc_ASK	cd06624	8.8e-06	512	789
STKc_SLK	cd06643	6.4e-06	512	812
PTKc_InsR_like	cd05032	1.2e-74	513	788
PTKc_EphR	cd05033	1.1e-55	513	790
PTKc_Src_like	cd05034	9.8e-63	513	789
PTKc_Jak_rpt2	cd05038	8.3e-54	513	790
PTKc_Musk	cd05050	2.2e-73	513	788
PTKc_Tec_like	cd05059	1.4e-42	513	790
PTKc_Abl	cd05052	3.5e-74	513	790
PTKc_InsR	cd05061	3.7e-63	513	795
PTKc_IGF-1R	cd05062	4.9e-64	513	788
PTKc_EphR_A2	cd05063	6.5e-46	513	790
PTKc_EphR_A10	cd05064	2.4e-37	513	790
PTKc_EphR_B	cd05065	9.7e-50	513	790
PTKc_EphR_A	cd05066	1.2e-50	513	790
PTKc_Lck_Blk	cd05067	2.6e-49	513	789
PTKc_Yes	cd05069	1.6e-37	513	789
PTKc_Fyn_Yrk	cd05070	2.2e-41	513	789
PTKc_Src	cd05071	2e-41	513	791
PTKc_Lyn	cd05072	1.6e-45	513	789
PTKc_Hck	cd05073	6.6e-51	513	789
PTKc_Jak2_Jak3_rpt2	cd05081	3.7e-32	513	790
PTKc_Csk	cd05082	6.7e-50	513	789
PTKc_Ror1	cd05090	2.2e-40	513	789
PTKc_TrkA	cd05092	1.2e-52	513	795
PTKc_TrkB	cd05093	4.2e-48	513	806
PTKc_TrkC	cd05094	6.8e-29	513	806
PTKc_DDR2	cd05095	6.5e-50	513	788
PTKc_DDR1	cd05096	1.1e-40	513	788
PTKc_DDR_like	cd05097	7.7e-53	513	788
PTKc_Frk_like	cd05068	6.2e-69	513	789
PTKc_VEGFR2	cd05103	7.7e-29	513	794
PTKc_FGFR3	cd05100	1.9e-42	513	825
PTKc_Itk	cd05112	3.8e-56	513	787
PTKc_Btk_Bmx	cd05113	4.7e-56	513	787
PTKc_Tec_Rlk	cd05114	8.1e-53	513	787
STKc_BUR1	cd07866	7.1e-06	513	779
PTKc_Srm_Brk	cd05148	7.1e-51	514	789
STKc_myosinIII_like	cd06608	2.1e-07	514	789
STKc_MAP4K3_like	cd06613	2.5e-09	514	786
STKc_MST1_2	cd06612	2.1e-07	514	780
STKc_MST4	cd06640	1.1e-05	514	811
STKc_MST3	cd06641	8.4e-06	514	811
STKc_STK25-YSK1	cd06642	8.1e-07	514	814
PTKc_Jak1_rpt2	cd05079	3.6e-30	515	790
PTKc_Ror2	cd05091	6.1e-33	515	789
PKc_MAPKK_Pek1_like	cd06621	7e-05	515	790
STKc_MEKK2	cd06652	0.0002	515	788
STKc_MEKK3_like_1	cd06653	5.2e-05	515	788
STKc_MAPK15	cd07852	4.1e-05	515	807
STKc_CDKL2_3	cd07846	9.3e-05	515	787
PTKc_Tie1	cd05089	1.4e-50	516	819
STKc_phototropin_lik	cd05574	4.7e-05	516	790
STKc_PKA	cd05580	4.7e-07	516	831
STKc_DMPK_like	cd05597	0.00091	516	845
STKc_PDK1	cd05581	6.1e-10	516	779
STKc_PRKX_like	cd05612	6.1e-06	516	832
STKc_ROCK_NDR_like	cd05573	2.3e-05	516	845
PKc_MAPKK	cd06605	6.6e-05	516	794
STKc_MST3_like	cd06609	1.5e-06	516	814
STKc_OSR1_SPAK	cd06610	2.7e-08	516	779
PKc_MKK3_6	cd06617	6.4e-05	516	801
PKc_MAPKK_PBS2_like	cd06622	8.3e-05	516	822
PKc_MAPKK_plant_like	cd06623	1.1e-08	516	796
STKc_MEKK3_like	cd06625	2.9e-07	516	788
STKc_NAK1_like	cd06917	1.4e-06	516	794
STKc_CdkB_plant	cd07837	7.9e-06	516	805
STKc_CDK6	cd07862	0.00018	516	824
STKc_CDK12	cd07864	5.3e-05	516	819
STKc_Nek6_Nek7	cd08224	4.6e-06	516	791
STKc_Nek6	cd08228	2.7e-05	516	795
STKc_Nek7	cd08229	4.2e-07	516	791
SPS1	COG0515	1.5e-17	516	889
PTKc_RET	cd05045	2.7e-62	517	793
PKc_STE	cd05122	2.1e-10	517	779
STKc_Yank1	cd05578	8.9e-10	517	796
STKc_MSK_N	cd05583	0.00063	517	813
STKc_cPKC	cd05587	5.3e-06	517	872
STKc_GRK4_like	cd05605	6.8e-07	517	832
STKc_cPKC_alpha	cd05615	7.3e-06	517	851
STKc_cPKC_beta	cd05616	6.4e-05	517	821
STKc_GRK6	cd05630	9e-05	517	827
STKc_GRK4	cd05631	3.6e-05	517	827
STKc_GRK5	cd05632	2.1e-05	517	827
STKc_MAPKKK	cd06606	1.8e-16	517	780
STKc_MEKK4	cd06626	2.7e-05	517	789
STKc_MAPKKK_Byr2_lik	cd06628	3.9e-08	517	789
STKc_MEKK1	cd06630	2.9e-05	517	780
STKc_YSK4	cd06631	2.9e-07	517	787
STKc_Cdc7_like	cd06627	5.6e-12	517	779
STKc_MEKK3	cd06651	1.3e-06	517	793
STKc_CCRK	cd07832	3.3e-08	517	780
STKc_Pho85	cd07836	0.00061	517	804
STKc_MAPK	cd07834	7e-07	517	812
STKc_CDK7	cd07841	1e-08	517	787
STKc_CDK8_like	cd07842	2.6e-05	517	779
STKc_TDY_MAPK_plant	cd07859	0.00036	517	860
STKc_CDK2_3	cd07860	0.00041	517	824
STKc_CDK4	cd07863	1.3e-05	517	804
STKc_Nek	cd08215	8.2e-12	517	787
STKc_Nek2	cd08217	1.4e-06	517	787
STKc_Nek1	cd08218	2.8e-05	517	787
STKc_Nek3	cd08219	4.2e-08	517	786
STKc_Nek9	cd08221	3.7e-05	517	784
STKc_Nek11	cd08222	3.3e-05	517	787
STKc_Nek4	cd08223	1.2e-06	517	787
STKc_Nek5	cd08225	0.00021	517	786
STKc_Nek8	cd08220	0.00029	517	795
STKc_Nek10	cd08528	0.00037	517	788
STKc_CNK2-like	cd08530	7.3e-06	517	795
STKc_FA2-like	cd08529	3e-09	517	786
PTKc_Axl_like	cd05035	5.8e-220	518	790
PTKc_Tyro3	cd05074	5.3e-227	518	790
PTKc_Axl	cd05075	8e-159	518	790
STKc_CMGC	cd05118	2.5e-08	518	779
STKc_PKN	cd05589	2.6e-06	518	850
PKc_MKK4	cd06616	0.00063	518	803
STKc_CDK_like	cd07829	2.1e-10	518	779
STKc_CDK1_like	cd07835	6.6e-05	518	804
STKc_MAK_like	cd07830	4.5e-08	518	787
STKc_CDK4_6_like	cd07838	1.3e-05	518	779
STKc_CDK9_like	cd07840	0.00057	518	779
STKc_MAPK4_6	cd07854	0.00051	518	860
PK_STRAD	cd08216	6.1e-05	519	795
STKc_p70S6K	cd05584	0.00027	521	844
STKc_MAPKKK_Bck1_lik	cd06629	1.9e-05	521	780
STKc_MEKK1_plant	cd06632	1.7e-08	521	780
STKc_CDK8	cd07868	0.00058	521	804
PTKc	cd00192	1.4e-127	522	787
PTK_Jak_rpt1	cd05037	1.2e-09	522	787
PTKc_Ack_like	cd05040	2.7e-61	522	788
PTKc_Fes_like	cd05041	5.7e-60	522	788
PTKc_c-ros	cd05044	1.5e-80	522	788
PTKc_Aatyk	cd05042	3.6e-15	522	779
PTKc_Tie	cd05047	5.8e-56	522	791
PTKc_Met_Ron	cd05058	3.2e-91	522	792
PTKc_Syk_like	cd05060	6.1e-64	522	791
PTK_Jak1_rpt1	cd05077	2.1e-09	522	787
PTK_Jak2_Jak3_rpt1	cd05078	1.9e-09	522	787
PTKc_Tyk2_rpt2	cd05080	1.6e-20	522	791
PTKc_Fes	cd05084	1.1e-57	522	788
PTKc_Fer	cd05085	5.8e-56	522	788
PTKc_Aatyk2	cd05086	2e-18	522	788
PTKc_Aatyk1_Aatyk3	cd05087	1.9e-28	522	788
PTKc_Syk	cd05116	1.4e-50	522	791
STKc_PKC	cd05570	1.1e-07	522	829
STKc_PKB	cd05571	1.4e-08	522	873
STKc_RSK_N	cd05582	6e-05	522	850
STKc_aPKC	cd05588	0.00028	522	872
STKc_nPKC_eta	cd05590	7.7e-05	522	851
STKc_nPKC_epsilon	cd05591	1.7e-05	522	872
STKc_nPKC_theta_delt	cd05592	4.5e-06	522	867
STKc_PKB_alpha	cd05594	4.5e-07	522	861
STKc_PKB_gamma	cd05593	6.3e-06	522	857
STKc_PKB_beta	cd05595	8.1e-06	522	874
STKc_SGK1	cd05602	0.0002	522	868
STKc_SGK2	cd05603	2.2e-05	522	860
STKc_aPKC_zeta	cd05617	0.00021	522	872
STKc_nPKC_theta	cd05619	2.1e-07	522	853
STKc_nPKC_delta	cd05620	0.00071	522	853
STKc_MOK	cd07831	3.8e-05	522	779
PKc	cd00180	6.8e-52	524	790
PTKc_Zap-70	cd05115	1.6e-49	524	791
STKc_AGC	cd05123	8.3e-11	524	779
STKc_cGK_PKG	cd05572	3.2e-07	524	786
STKc_GRK	cd05577	7.9e-05	524	789
STKc_YPK1_like	cd05585	4.9e-06	524	849
STKc_GRK7	cd05607	0.00017	524	822
STKc_GRK1	cd05608	7.1e-07	524	807
STKc_MAST_like	cd05579	3.7e-06	524	780
ig	pfam00047	4.5e-07	57	119
fn3	pfam00041	7.7e-07	226	310
fn3	pfam00041	0.00023	324	406
Pkinase	pfam00069	1e-33	518	786
I-set	pfam07679	3.2e-07	43	135
IG	smart00409	3.5e-18	49	136
IG_like	smart00410	3.5e-18	49	136
V-set	pfam07686	8.5e-07	51	135
IGc2	smart00408	5.9e-21	56	124
IG	smart00409	8.2e-05	145	222
IG_like	smart00410	8.2e-05	145	222
FN3	smart00060	3.1e-11	225	307
Pkinase_Tyr	pfam07714	5.9e-140	518	786
TyrKc	smart00219	6.8e-126	518	790
STYKc	smart00221	9.1e-49	518	804
S_TKc	smart00220	5.7e-39	528	790

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_041876	Polymorphism	p.ALA831THR	N/A
Swiss-Prot	VAR_045889	Polymorphism	p.ALA815VAL	N/A
dbSNP	rs17857364	Polymorphism	p.ARG824GLY	N/A
Swiss-Prot	VAR_045888	Polymorphism	p.GLY542SER	N/A
dbSNP	rs12148316	Polymorphism	p.ILE346ASN	N/A
Swiss-Prot	VAR_045890	Polymorphism	p.LEU819MET	N/A
Swiss-Prot	VAR_045886	Polymorphism	p.PRO21LEU	N/A
dbSNP	rs62001448	Polymorphism	p.VAL669LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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