Results for the protein: Q15052

Results for the Protein: Q15052

17371603

9459

ARHGEF6

NCBI, UniProt

ARHG6_HUMAN RecName: Full=Rho guanine nucleotide exchange factor 6; AltName: Full=Alpha-Pix; AltName: Full=COOL-2; AltName: Full=PAK-interacting exchange factor alpha; AltName: Full=Rac/Cdc42 guanine nucleotide exchange factor 6

			0 1 0 0 1

Tips:

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Default View: CH - pfam00307 CH - cd00014 CH - smart00033 SH3 - smart00326 SH3_2 - pfam07653 SH3 - cd00174 SH3_1 - pfam00018 RhoGEF - cd00160 RhoGEF - smart00325 RhoGEF - pfam00621 PH_Cool_Pix - cd01225 PH - pfam00169 PH - smart00233 PH - cd00821 PH-like - cd00900	Swiss-Prot Protein: Q15052 Identical to: NP_004831 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
SH3	cd00174	1.3e-23	164	216
RhoGEF	cd00160	7.4e-53	242	419
PH_Cool_Pix	cd01225	1.3e-93	439	549
PH	cd00821	5.6e-09	452	546
PH-like	cd00900	6.2e-05	453	546
CH	pfam00307	1.8e-15	2	111
SH3_1	pfam00018	6.5e-17	166	211
RhoGEF	pfam00621	4.5e-38	246	420
PH	pfam00169	5.4e-16	450	548
CH	smart00033	1e-28	3	106
SH3	smart00326	2.8e-24	161	217
SH3_2	pfam07653	7.2e-16	164	216
RhoGEF	smart00325	1.5e-48	245	420
PH	smart00233	9.8e-13	450	548

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_051981	Polymorphism	p.GLN297HIS	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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