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Results for the Protein:
NP_001122401
193083163
6092
ROBO2
NCBI
roundabout homolog 2 isoform ROBO2a [Homo sapiens]
Known Diseases associated with this Protein:
VESICOURETERAL REFLUX 2
2
1
2
1
0
Tips:
The Domains on the Default View are decided by the Domain's E-Value.
Clicking a check box will display or hide the correlated domain.
To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.
Default View:
I-set - pfam07679
IG_like - smart00410
IG - smart00409
IGc2 - smart00408
V-set - pfam07686
FN3 - smart00060
RefSeq Protein:
NP_001122401
Default View:
Domains
found on the Protein
Domain ↕
CD Accession ↕
E-Value ↕
Start ↕
End ↕
IG
smart00409
4.4e-15
53
145
IG_like
smart00410
4.4e-15
53
145
IGc2
smart00408
3.6e-12
60
133
I-set
pfam07679
1.2e-11
149
237
IG
smart00409
9.7e-17
155
238
IG_like
smart00410
9.7e-17
155
238
IGc2
smart00408
8.8e-11
162
226
I-set
pfam07679
1.4e-32
241
326
IG
smart00409
8.9e-18
247
327
IG_like
smart00410
8.9e-18
247
327
IGc2
smart00408
6.7e-12
254
316
I-set
pfam07679
1.4e-17
330
424
IG
smart00409
1.1e-19
336
425
IG_like
smart00410
1.1e-19
336
425
V-set
pfam07686
2.7e-06
338
424
IGc2
smart00408
1.9e-10
343
414
I-set
pfam07679
1.4e-17
434
521
IG
smart00409
1.2e-19
440
522
IG_like
smart00410
1.2e-19
440
522
V-set
pfam07686
8.8e-06
442
523
IGc2
smart00408
9.2e-14
447
511
FN3
smart00060
8.6e-20
538
620
FN3
smart00060
5.2e-08
652
737
FN3
smart00060
2.8e-12
756
839
Table of Mutations found on the Protein
Source ↕
Mut_ID ↕
Class ↕
HGVS ↕
Disease ↕
dbSNP
rs6788280
Polymorphism
p.ALA12GLU
N/A
OMIM
602431.0002
Disease
p.ALA1236THR
VESICOURETERAL REFLUX 2
OMIM
602431.0001
Disease
p.ILE945THR
VESICOURETERAL REFLUX 2
Please Cite:
Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.
DMDM_info@umbc.edu
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