Results for the protein: P29322

Results for the Protein: P29322

19857975

2046

EPHA8

NCBI, UniProt

EPHA8_HUMAN RecName: Full=Ephrin type-A receptor 8; AltName: Full=EPH- and ELK-related kinase; AltName: Full=EPH-like kinase 3; Short=EK3; Short=hEK3; AltName: Full=Tyrosine-protein kinase receptor EEK; Flags: Precursor

			0 10 0 2 8

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Swiss-Prot Protein: P29322

Identical to: NP_065387

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
FN3	cd00063	4.7e-20	440	531
PTKc_PDGFR_beta	cd05107	6.7e-08	473	897
PTKc_VEGFR	cd05054	4.1e-19	491	899
PTKc_CSF-1R	cd05106	2.7e-12	596	897
STKc_TAO1	cd06635	0.00016	596	926
PTKc_Kit	cd05104	4.5e-12	598	896
STKc_PAK5	cd06658	1.2e-05	603	918
PTKc_DDR2	cd05095	1.5e-47	608	894
PTKc_PDGFR_alpha	cd05105	1.5e-10	611	898
PTKc_FGFR1	cd05098	1.1e-36	614	900
PTKc_FGFR2	cd05101	1e-40	615	900
STKc_PAK1	cd06654	0.00064	615	909
STKc_PAK6	cd06659	5.2e-07	615	911
PTKc_PDGFR	cd05055	4e-14	616	896
STKc_PAK	cd06614	5.7e-11	616	909
STKc_PAK4	cd06657	2.7e-05	616	920
STKc_PAK_I	cd06647	0.00051	617	922
STKc_PAK_II	cd06648	7.6e-09	617	896
STKc_PAK3	cd06656	0.00026	617	910
STKc_TAO2	cd06634	4.8e-05	618	919
PTKc_FGFR4	cd05099	1.9e-48	619	914
PTK_Tyk2_rpt1	cd05076	1e-07	620	893
PKc_MKK7	cd06618	1.2e-08	620	922
STKc_myosinIIIA	cd06638	0.00024	620	894
STKc_CDK9	cd07865	0.00024	620	907
PTKc_FGFR3	cd05100	9.6e-34	622	937
STKc_Sty1_Hog1	cd07856	7.7e-05	623	945
STKc_JNK3	cd07874	0.001	623	948
STKc_MAP4K4_6	cd06636	0.00099	624	896
STKc_STK10_LOK	cd06644	5.7e-05	624	908
STKc_JNK	cd07850	4.1e-05	624	946
PTKc_HER4	cd05110	1.1e-44	625	928
STKc_MAP4K3	cd06645	8.5e-05	625	893
STKc_ASK	cd06624	4.8e-09	626	896
STKc_p38	cd07851	0.00026	626	949
STKc_ERK5	cd07855	0.00035	626	942
PTKc_EGFR_like	cd05057	5.6e-73	627	906
PTKc_VEGFR3	cd05102	2.2e-19	627	899
PTKc_VEGFR2	cd05103	5.9e-20	627	899
PTKc_EGFR	cd05108	2.1e-45	627	941
PTKc_HER2	cd05109	3.5e-51	627	906
PTK_HER3	cd05111	1.8e-44	627	906
PTKc_ALK_LTK	cd05036	1.9e-55	628	894
PTKc_FAK	cd05056	5.2e-83	628	901
STKc_TNIK	cd06637	8.8e-05	628	894
PTKc_InsR_like	cd05032	7.2e-66	629	894
PTKc_Src_like	cd05034	2.5e-96	629	895
PTKc_Csk_like	cd05039	1.7e-70	629	898
PTKc_Ror	cd05048	8.4e-51	629	895
PTKc_Trk	cd05049	5.3e-63	629	894
PTKc_Musk	cd05050	2.5e-67	629	894
PTKc_DDR	cd05051	1.1e-44	629	894
PTKc_FGFR	cd05053	4.1e-40	629	897
PTKc_Abl	cd05052	2.7e-77	629	896
PTKc_InsR	cd05061	2.6e-47	629	904
PTKc_EphR_A2	cd05063	3.1e-178	629	896
PTKc_EphR_A10	cd05064	4.8e-147	629	896
PTKc_IGF-1R	cd05062	1.8e-45	629	894
PTKc_Lck_Blk	cd05067	6.1e-74	629	895
PTKc_Frk_like	cd05068	3.5e-93	629	895
PTKc_Yes	cd05069	7.6e-68	629	895
PTKc_Fyn_Yrk	cd05070	9.5e-71	629	895
PTKc_Src	cd05071	1.8e-67	629	897
PTKc_Lyn	cd05072	2.6e-71	629	895
PTKc_Hck	cd05073	1.5e-69	629	895
PTKc_Ror1	cd05090	5.5e-49	629	895
PTKc_Ror2	cd05091	5.6e-45	629	895
PTKc_TrkB	cd05093	5.7e-49	629	903
PTKc_TrkC	cd05094	2.5e-29	629	903
PTKc_DDR1	cd05096	3.2e-40	629	894
PTKc_DDR_like	cd05097	4.4e-50	629	894
PTKc_Csk	cd05082	1.3e-61	629	895
PTKc_TrkA	cd05092	2.4e-55	629	894
STKc_TAO	cd06607	0.00016	629	919
PKc_MAPKK_Byr1_like	cd06620	7.7e-08	629	906
STKc_myosinIIIB	cd06639	0.00061	629	897
STKc_MST4	cd06640	6.8e-08	629	915
STKc_MST3	cd06641	7.2e-07	629	903
STKc_STK25-YSK1	cd06642	1.5e-07	629	903
STKc_TEY_MAPK_plant	cd07858	3.5e-05	629	955
STKc_CDK12	cd07864	4.3e-08	629	917
STKc_PCTAIRE3	cd07871	0.00023	629	921
PTKc_EphR	cd05033	6.7e-205	630	896
PTK_Ryk	cd05043	3.7e-24	630	895
PTKc_Tec_like	cd05059	2.1e-73	630	893
PTKc_EphR_B	cd05065	2.1e-177	630	896
PTKc_EphR_A	cd05066	1.5e-205	630	896
PTKc_Jak1_rpt2	cd05079	6.8e-40	630	896
PTKc_Jak2_Jak3_rpt2	cd05081	1.8e-46	630	896
PTKc_Chk	cd05083	5.5e-64	630	895
PTKc_Tie2	cd05088	1.5e-40	630	923
PTKc_Btk_Bmx	cd05113	3.7e-75	630	893
PTKc_Itk	cd05112	9.4e-72	630	893
PTKc_Tec_Rlk	cd05114	1.5e-72	630	893
STKc_MAPK15	cd07852	0.00031	630	917
STKc_PFTAIRE2	cd07870	2.4e-05	630	921
STKc_PCTAIRE_like	cd07844	4.9e-05	630	921
PTK_CCK4	cd05046	1.6e-32	631	894
STKc_MAP4K3_like	cd06613	5.9e-11	631	893
STKc_BUR1	cd07866	1.9e-05	631	868
PTKc_Jak_rpt2	cd05038	8.8e-65	632	896
STKc_myosinIII_like	cd06608	2.9e-06	632	891
PKc_MKK3_6	cd06617	8e-07	632	908
STKc_SLK	cd06643	1.9e-05	632	911
STKc_MEKK3_like_1	cd06653	3.8e-05	632	894
STKc_CDK10	cd07845	9.8e-07	632	917
STKc_ERK1_2_like	cd07849	1.3e-05	632	926
STKc_Nek6_Nek7	cd08224	1.1e-07	632	897
STKc_Nek6	cd08228	8.6e-06	632	897
STKc_Nek7	cd08229	3.7e-08	632	897
PTKc_Tie1	cd05089	3.3e-41	633	922
STKc_phototropin_lik	cd05574	4.9e-07	633	906
STKc_PKA	cd05580	2.2e-05	633	908
STKc_DMPK_like	cd05597	0.00092	633	959
STKc_MAST	cd05609	0.00012	633	952
STKc_PRKX_like	cd05612	1.3e-05	633	925
STKc_ROCK_NDR_like	cd05573	0.00023	633	922
PKc_MAPKK	cd06605	2.2e-10	633	890
STKc_MST3_like	cd06609	6.8e-09	633	903
STKc_OSR1_SPAK	cd06610	1.1e-09	633	888
PKc_MEK	cd06615	1e-05	633	921
PKc_MKK5	cd06619	2.8e-05	633	924
PKc_MAPKK_plant_like	cd06623	4.8e-11	633	894
STKc_Pho85	cd07836	9e-06	633	916
STKc_CDK9_like	cd07840	2.7e-09	633	917
STKc_CDK1_euk	cd07861	0.00044	633	915
SPS1	COG0515	3.3e-19	633	1003
PTKc_RET	cd05045	1.2e-39	634	899
STKc_MSK_N	cd05583	5.3e-05	634	918
STKc_cPKC	cd05587	0.00039	634	958
STKc_GRK4_like	cd05605	6.1e-05	634	914
STKc_MSK1_N	cd05613	0.00068	634	913
STKc_MSK2_N	cd05614	0.00018	634	961
STKc_cPKC_alpha	cd05615	0.00064	634	958
STKc_MAPKKK	cd06606	1.3e-17	634	886
STKc_Cdc7_like	cd06627	7e-16	634	888
STKc_MAPKKK_Byr2_lik	cd06628	3e-11	634	894
STKc_MEKK3	cd06651	3.7e-06	634	888
STKc_CCRK	cd07832	4.5e-08	634	916
STKc_MAPK	cd07834	1.7e-05	634	909
STKc_CDK7	cd07841	1.7e-06	634	903
STKc_MPK1	cd07857	0.00023	634	908
STKc_TDY_MAPK_plant	cd07859	5.8e-05	634	981
STKc_CDK4	cd07863	0.0005	634	921
STKc_Nek	cd08215	2.9e-15	634	895
STKc_Nek1	cd08218	1.7e-06	634	897
STKc_Nek3	cd08219	4.8e-10	634	894
STKc_Nek11	cd08222	6.5e-09	634	896
STKc_Nek5	cd08225	1.5e-06	634	892
STKc_Nek4	cd08223	2.6e-07	634	896
STKc_CNK2-like	cd08530	3.6e-07	634	892
STKc_Nek10	cd08528	8.5e-05	634	894
PTKc_Axl_like	cd05035	5.6e-56	635	896
PTKc_Tyro3	cd05074	2.8e-49	635	896
PTKc_Axl	cd05075	4.4e-40	635	896
PTKc_Tyk2_rpt2	cd05080	3.9e-17	635	897
STKc_PKN	cd05589	8e-05	635	957
STKc_SLK_like	cd06611	9.4e-08	635	898
PKc_MKK4	cd06616	1.2e-06	635	912
STKc_MAPKKK_Bck1_lik	cd06629	2.4e-11	635	886
PKc_STE	cd05122	6.6e-13	636	887
PTKc_Srm_Brk	cd05148	1.9e-75	636	895
STKc_Yank1	cd05578	1e-06	636	885
STKc_PDK1	cd05581	1.8e-06	636	876
STKc_CRIK	cd05601	4.9e-05	636	922
STKc_MST1_2	cd06612	2.8e-09	636	888
STKc_CDK_like	cd07829	1.4e-08	636	907
STKc_CDK1_like	cd07835	2.7e-05	636	928
STKc_CdkB_plant	cd07837	4.1e-05	636	922
STKc_CDK5	cd07839	9.2e-05	636	922
STKc_CDKL1_4	cd07847	9.8e-07	636	944
STKc_CDK2_3	cd07860	0.00023	636	921
STKc_Nek8	cd08220	2.9e-07	636	896
PK_STRAD_alpha	cd08227	0.00047	636	998
STKc_FA2-like	cd08529	5.5e-09	636	888
STKc_MOK	cd07831	8.8e-05	637	909
STKc_CMGC	cd05118	8.6e-10	638	888
STKc_RSK_N	cd05582	1.2e-06	638	959
STKc_p70S6K	cd05584	7.1e-05	638	959
PKc_MAPKK_Pek1_like	cd06621	1.5e-05	638	909
PKc_MAPKK_PBS2_like	cd06622	1.6e-06	638	946
STKc_MEKK4	cd06626	8e-07	638	888
STKc_CDKL	cd07833	0.00027	638	885
STKc_CDKL2_3	cd07846	0.0001	638	890
PTKc	cd00192	6.1e-124	639	893
PTK_Jak_rpt1	cd05037	3.4e-11	639	893
PTKc_Ack_like	cd05040	1.3e-66	639	894
PTKc_Fes_like	cd05041	1.9e-82	639	894
PTKc_Aatyk	cd05042	6e-13	639	894
PTKc_c-ros	cd05044	1.9e-55	639	894
PTKc_Tie	cd05047	3.8e-46	639	897
PTKc_Met_Ron	cd05058	1.3e-63	639	898
PTKc_Syk_like	cd05060	3.6e-79	639	897
PTK_Jak1_rpt1	cd05077	6.5e-10	639	893
PTK_Jak2_Jak3_rpt1	cd05078	1.2e-11	639	893
PTKc_Fes	cd05084	2.4e-73	639	894
PTKc_Fer	cd05085	1e-67	639	894
PTKc_Aatyk2	cd05086	1.1e-15	639	894
PTKc_Aatyk1_Aatyk3	cd05087	9.4e-16	639	894
PTKc_Syk	cd05116	1.2e-61	639	897
STKc_PKC	cd05570	1.4e-05	639	924
STKc_PKB	cd05571	4.1e-06	639	959
STKc_nPKC_epsilon	cd05591	0.00023	639	960
STKc_PKB_alpha	cd05594	0.00014	639	960
STKc_PKB_gamma	cd05593	0.00031	639	962
STKc_PKB_beta	cd05595	0.00034	639	959
STKc_SGK2	cd05603	0.0002	639	968
STKc_nPKC_theta	cd05619	0.00017	639	955
STKc_MEKK3_like	cd06625	4e-09	639	894
STKc_MEKK1	cd06630	4e-07	639	886
STKc_YSK4	cd06631	9.4e-07	639	892
STKc_MEKK1_plant	cd06632	2.5e-08	639	889
STKc_MAK_like	cd07830	2.7e-07	639	885
STKc_Nek2	cd08217	4.4e-07	639	892
STKc_NAK1_like	cd06917	8.3e-07	640	900
PKc	cd00180	4e-58	641	892
PTKc_Zap-70	cd05115	3.2e-71	641	897
STKc_AGC	cd05123	2.2e-07	641	885
STKc_cGK_PKG	cd05572	8.3e-05	641	877
STKc_MAST_like	cd05579	8e-06	641	894
STKc_YPK1_like	cd05585	0.00028	641	956
STKc_Nek9	cd08221	4.3e-08	650	894
STKc_CDC2L1	cd07843	0.00016	660	896
	cd00166	1.9e-21	929	992
Ephrin_lbd	pfam01404	1.3e-120	31	204
fn3	pfam00041	5.8e-09	330	422
fn3	pfam00041	1.9e-20	438	524
Pkinase	pfam00069	3.7e-38	635	892
SAM_1	pfam00536	2e-25	931	992
EPH_lbd	smart00615	1.9e-111	31	203
FN3	smart00060	1.9e-07	329	421
FN3	smart00060	1.3e-17	440	521
Pkinase_Tyr	pfam07714	1.7e-143	635	892
TyrKc	smart00219	1.3e-127	635	892
STYKc	smart00221	9.2e-52	635	922
S_TKc	smart00220	1e-39	645	896
SAM_2	pfam07647	1.3e-13	927	992
SAM	smart00454	3.2e-19	927	994

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042156	Polymorphism	p.ARG179CYS	N/A
dbSNP	rs62642537	Polymorphism	p.ARG707CYS	N/A
Swiss-Prot	VAR_042157	Polymorphism	p.ARG198LEU	N/A
Swiss-Prot	VAR_042155	Polymorphism	p.ASN123LYS	N/A
dbSNP	rs999765	Polymorphism	p.GLU612GLN	N/A
Swiss-Prot	VAR_042153	Polymorphism	p.GLY45SER	N/A
Swiss-Prot	VAR_061292	Polymorphism	p.PRO321LEU	N/A
Swiss-Prot	VAR_042158	Polymorphism	p.PRO860LEU	N/A
Swiss-Prot	VAR_042154	Polymorphism	p.VAL60LEU	N/A
Swiss-Prot	VAR_022107	Polymorphism	p.VAL444MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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