Results for the protein: Q99466

Results for the Protein: Q99466

20139103

4855

NOTCH4

NCBI, UniProt

NOTC4_HUMAN RecName: Full=Neurogenic locus notch homolog protein 4; Short=Notch 4; Short=hNotch4; Contains: RecName: Full=Notch 4 extracellular truncation; Contains: RecName: Full=Notch 4 intracellular domain; Flags: Precursor

			0 14 0 9 5

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Default View: EGF - smart00181 EGF_CA - smart00179 EGF_CA - pfam07645 NL - smart00004 NODP - pfam07684 ANK - smart00248	Swiss-Prot Protein: Q99466 Identical to: NP_004548 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
EGF	smart00181	9.2e-05	67	115
EGF	smart00181	0.00042	121	155
EGF	smart00181	6.3e-07	159	192
EGF_CA	pfam07645	7.1e-09	194	231
EGF_CA	smart00179	1.6e-13	194	232
EGF	smart00181	5.3e-08	197	232
EGF_CA	smart00179	6.4e-05	276	312
EGF	smart00181	6.5e-07	279	312
EGF_CA	pfam07645	1.4e-10	314	352
EGF_CA	smart00179	4.4e-13	314	353
EGF	smart00181	6e-09	317	353
EGF_CA	smart00179	1.6e-10	355	391
EGF	smart00181	1.4e-06	358	391
EGF	smart00181	0.0009	395	430
EGF_CA	pfam07645	2.8e-09	432	472
EGF_CA	smart00179	2e-17	432	473
EGF	smart00181	5.4e-11	435	473
EGF_CA	smart00179	4.9e-14	475	511
EGF	smart00181	1e-08	478	511
EGF_CA	smart00179	1.5e-14	513	549
EGF	smart00181	2.4e-11	516	549
EGF_CA	pfam07645	0.00079	551	586
EGF_CA	smart00179	1.6e-16	551	587
EGF	smart00181	1.7e-10	554	587
EGF_CA	smart00179	3.5e-14	589	625
EGF	smart00181	1e-09	592	625
EGF_CA	smart00179	0.0003	691	727
EGF	smart00181	1.8e-06	694	727
EGF	smart00181	6.2e-07	732	765
EGF_CA	smart00179	0.00083	733	765
EGF_CA	smart00179	1.1e-11	767	803
EGF	smart00181	6.3e-10	770	803
EGF	smart00181	1e-07	809	842
EGF_CA	smart00179	0.00059	810	842
EGF_CA	smart00179	0.00021	845	880
EGF	smart00181	4.3e-06	847	880
EGF	smart00181	2.1e-11	885	928
EGF_CA	smart00179	9.5e-05	894	928
EGF_CA	smart00179	1.6e-08	930	966
EGF	smart00181	4.5e-09	933	966
EGF_CA	smart00179	1.4e-12	968	1004
EGF	smart00181	7e-11	971	1004
EGF_CA	smart00179	2.1e-09	1006	1044
EGF	smart00181	2.3e-05	1009	1044
EGF_CA	smart00179	1.1e-05	1046	1085
EGF	smart00181	6.4e-07	1049	1085
NL	smart00004	3.7e-12	1163	1203
NL	smart00004	1e-15	1207	1245
NL	smart00004	2.3e-16	1246	1284
NODP	pfam07684	2e-13	1377	1440
ANK	smart00248	8.7e-05	1633	1662
ANK	smart00248	0.0002	1733	1762

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_048993	Polymorphism	p.ARG1346PRO	N/A
dbSNP	rs520692	Polymorphism	p.ASP272GLY	N/A
dbSNP	rs520803	Polymorphism	p.GLN284HIS	N/A
Swiss-Prot	VAR_012868	Polymorphism	p.GLU317GLN	N/A
dbSNP	rs17604492	Polymorphism	p.GLY942ARG	N/A
dbSNP	rs8192591	Polymorphism	p.GLY534SER	N/A
dbSNP	rs9267835	Polymorphism	p.GLY835VAL	N/A
Swiss-Prot	VAR_012870	Polymorphism	p.LYS851ARG	N/A
dbSNP	rs915894	Polymorphism	p.LYS117GLN	N/A
dbSNP	rs2071282	Polymorphism	p.PRO204LEU	N/A
Swiss-Prot	VAR_033829	Polymorphism	p.PRO206LEU	N/A
Swiss-Prot	VAR_048991	Polymorphism	p.SER809ILE	N/A
dbSNP	rs8192585	Polymorphism	p.SER244LEU	N/A
dbSNP	rs422951	Polymorphism	p.THR320ALA	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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