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Results for the Protein: P43250
20141386

GRK6_HUMAN RecName: Full=G protein-coupled receptor kinase 6; AltName: Full=G protein-coupled receptor kinase GRK6
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

RGS - smart00315
RGS - pfam00615
STKc_ROCK - cd05596
STKc_ROCK1 - cd05622
STKc_ROCK2 - cd05621
STKc_PAK6 - cd06659
STKc_PAK_I - cd06647
STKc_PAK4 - cd06657
STKc_PAK5 - cd06658
STKc_JNK2 - cd07876
STKc_myosinIIIB - cd06639
STKc_p38 - cd07851
STKc_PAK_II - cd06648
STKc_ERK5 - cd07855
STKc_myosinIIIA - cd06638
STKc_JNK1 - cd07875
STKc_MAP4K4_6 - cd06636
STKc_JNK - cd07850
STKc_PAK - cd06614
STKc_TAO - cd06607
STKc_PAK2 - cd06655
STKc_PAK1 - cd06654
STKc_JNK3 - cd07874
STKc_PAK3 - cd06656
STKc_STK10_LOK - cd06644
STKc_p38alpha_MAPK14 - cd07877
STKc_CDK12 - cd07864
STKc_CDK9 - cd07865
PTKc_Chk - cd05083
STKc_p38delta_MAPK13 - cd07879
STKc_p38beta_MAPK11 - cd07878
STKc_MAP4K3 - cd06645
STKc_ASK - cd06624
STKc_CDK10 - cd07845
STKc_TNIK - cd06637
PKc_MKK7 - cd06618
PTKc_DDR2 - cd05095
STKc_p38gamma_MAPK12 - cd07880
PTKc_DDR1 - cd05096
PTK_HER3 - cd05111
STKc_MAP4K5 - cd06646
PTKc_FAK - cd05056
PTKc_ALK_LTK - cd05036
PTKc_Tie2 - cd05088
PTKc_EGFR_like - cd05057
PKc_MEK2 - cd06649
PTKc_DDR_like - cd05097
PKc_MEK1 - cd06650
PTKc_Ror1 - cd05090
PTKc_Ror - cd05048
PTK_CCK4 - cd05046
PTKc_EphR_A2 - cd05063
PTKc_Trk - cd05049
PTKc_TrkB - cd05093
PTKc_TrkC - cd05094
PTKc_TrkA - cd05092
PTKc_Csk - cd05082
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Tyk2_rpt2 - cd05080
PTKc_Jak1_rpt2 - cd05079
PTKc_Btk_Bmx - cd05113
STKc_TEY_MAPK_plant - cd07858
PTKc_Hck - cd05073
PKc_MAPKK_Byr1_like - cd06620
PTKc_Tec_Rlk - cd05114
PTKc_HER2 - cd05109
PTKc_Itk - cd05112
PTKc_EGFR - cd05108
PTKc_InsR - cd05061
PTKc_Musk - cd05050
PTKc_Abl - cd05052
PTKc_Tec_like - cd05059
PTK_Ryk - cd05043
PTKc_Lyn - cd05072
PTKc_Src_like - cd05034
PTKc_EphR - cd05033
PTKc_InsR_like - cd05032
PTKc_Jak_rpt2 - cd05038
PTKc_Fyn_Yrk - cd05070
PTKc_Yes - cd05069
PTKc_IGF-1R - cd05062
PTKc_Frk_like - cd05068
PTKc_Src - cd05071
PTKc_EphR_B - cd05065
PTKc_EphR_A - cd05066
PTKc_Lck_Blk - cd05067
STKc_Sty1_Hog1 - cd07856
STKc_PFTAIRE1 - cd07869
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE_like - cd07844
STKc_MST4 - cd06640
STKc_MST1_2 - cd06612
STKc_STK25-YSK1 - cd06642
STKc_MAP4K3_like - cd06613
PKc_MKK4 - cd06616
STKc_MST3 - cd06641
STKc_Nek6_Nek7 - cd08224
STKc_ERK1_2_like - cd07849
PTKc_Srm_Brk - cd05148
STKc_MEKK2 - cd06652
STKc_SLK - cd06643
STKc_MEKK3_like_1 - cd06653
STKc_MST3_like - cd06609
STKc_MEKK3_like - cd06625
STKc_NAK1_like - cd06917
PKc_MAPKK_PBS2_like - cd06622
PKc_MKK5 - cd06619
PKc_MEK - cd06615
PKc_MKK3_6 - cd06617
STKc_CDKL - cd07833
PKc_MAPKK_Pek1_like - cd06621
STKc_CDKL1_4 - cd07847
STKc_Nek7 - cd08229
STKc_Nek6 - cd08228
SPS1 - COG0515
STKc_PCTAIRE1 - cd07873
STKc_PCTAIRE2 - cd07872
STKc_CDKL5 - cd07848
STKc_PCTAIRE3 - cd07871
STKc_CdkB_plant - cd07837
PKc_MAPKK_plant_like - cd06623
STKc_DMPK_like - cd05597
STKc_LATS - cd05598
STKc_NDR_like - cd05599
STKc_Sid2p_Dbf2p - cd05600
STKc_PDK1 - cd05581
STKc_PKA - cd05580
PTKc_Tie1 - cd05089
STKc_ROCK_NDR_like - cd05573
STKc_phototropin_lik - cd05574
STKc_MAST - cd05609
STKc_myosinIII_like - cd06608
STKc_NDR2 - cd05627
STKc_NDR_like_fungal - cd05629
PKc_MAPKK - cd06605
STKc_CRIK - cd05601
STKc_LATS2 - cd05626
STKc_NDR1 - cd05628
STKc_PRKX_like - cd05612
STKc_LATS1 - cd05625
STKc_MRCK_alpha - cd05623
STKc_MRCK_beta - cd05624
STKc_CDK2_3 - cd07860
STKc_CDK1_euk - cd07861
STKc_BUR1 - cd07866
STKc_Nek - cd08215
STKc_CDK4 - cd07863
STKc_CDK5 - cd07839
STKc_Nek1 - cd08218
STKc_NLK - cd07853
STKc_MPK1 - cd07857
STKc_TDY_MAPK_plant - cd07859
STKc_Nek8 - cd08220
STKc_FA2-like - cd08529
STKc_CNK2-like - cd08530
STKc_CDK7 - cd07841
STKc_Nek10 - cd08528
STKc_Nek5 - cd08225
STKc_Nek9 - cd08221
STKc_Nek11 - cd08222
STKc_Nek4 - cd08223
STKc_Nek3 - cd08219
STKc_MAPKKK_Byr2_lik - cd06628
STKc_MSK1_N - cd05613
STKc_MSK2_N - cd05614
STKc_Pho85 - cd07836
STKc_cPKC_beta - cd05616
STKc_GRK4_like - cd05605
STKc_cPKC - cd05587
PTKc_RET - cd05045
PKc_STE - cd05122
STKc_Yank1 - cd05578
STKc_MSK_N - cd05583
STKc_GRK6 - cd05630
STKc_cPKC_alpha - cd05615
STKc_GRK4 - cd05631
STKc_MAPK - cd07834
STKc_MEKK3 - cd06651
STKc_MEKK1_plant - cd06632
STKc_YSK4 - cd06631
STKc_MEKK1 - cd06630
STKc_GRK5 - cd05632
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_CDK8 - cd07868
Pkinase - pfam00069
STYKc - smart00221
STKc_MAPK4_6 - cd07854
TyrKc - smart00219
Pkinase_Tyr - pfam07714
STKc_CDK_like - cd07829
STKc_PKN - cd05589
STKc_CMGC - cd05118
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MAK_like - cd07830
STKc_CDK4_6_like - cd07838
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
STKc_CDK1_like - cd07835
STKc_OSR1_SPAK - cd06610
STKc_CDK6 - cd07862
STKc_CDKL2_3 - cd07846
STKc_CCRK - cd07832
STKc_MEKK4 - cd06626
STKc_CDK8_like - cd07842
STKc_Nek2 - cd08217
STKc_CDC2L1 - cd07843
STKc_p70S6K - cd05584
STKc_RSK_N - cd05582
STKc_CDK9_like - cd07840
STKc_MOK - cd07831
STKc_SGK2 - cd05603
STKc_SGK1 - cd05602
STKc_PKB_beta - cd05595
STKc_SGK3 - cd05604
STKc_aPKC_zeta - cd05617
STKc_PKB_gamma - cd05593
STKc_nPKC_delta - cd05620
STKc_nPKC_theta - cd05619
STKc_aPKC_iota - cd05618
STKc_nPKC_theta_delt - cd05592
STKc_PKB_alpha - cd05594
PTKc_Fes_like - cd05041
PTKc_Ack_like - cd05040
PTKc - cd00192
PTKc_c-ros - cd05044
STKc_nPKC_epsilon - cd05591
PTKc_Met_Ron - cd05058
PTKc_Tie - cd05047
PTKc_Fes - cd05084
PTKc_Syk_like - cd05060
STKc_PKC - cd05570
STKc_aPKC - cd05588
STKc_nPKC_eta - cd05590
STKc_SGK - cd05575
STKc_PKB - cd05571
PTKc_Syk - cd05116
PTKc_Fer - cd05085
STKc_beta_ARK - cd05606
STKc_GRK3 - cd05633
STKc_SLK_like - cd06611
STKc_GRK1 - cd05608
STKc_GRK - cd05577
STKc_cGK_PKG - cd05572
STKc_AGC - cd05123
PTKc_Zap-70 - cd05115
PKc - cd00180
STKc_GRK7 - cd05607
STKc_MAST_like - cd05579
STKc_Sck1_like - cd05586
STKc_YPK1_like - cd05585
STKc_Rim15_like - cd05611
S_TKc - smart00220
STKc_MAPK15 - cd07852
S_TK_X - smart00133


Swiss-Prot Protein: P43250
Identical to: NP_001004106
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
STKc_ROCKcd055965e-12140501
STKc_ROCK2cd056212.2e-13160500
STKc_ROCK1cd056221.2e-11160501
STKc_PAK6cd066593.8e-09162474
STKc_PAK_Icd066473.4e-06163473
STKc_PAK4cd066572.8e-08163455
STKc_PAK5cd066581.4e-07164466
STKc_JNK2cd078763.3e-07164479
STKc_myosinIIIBcd066394.2e-07165449
STKc_myosinIIIAcd066381e-06167448
STKc_PAK_IIcd066488.7e-12167461
STKc_p38cd078512.5e-10167496
STKc_ERK5cd078557.7e-09167481
STKc_JNK1cd078751.1e-05168481
STKc_MAP4K4_6cd066360.00026169448
STKc_JNKcd078508.8e-07169491
STKc_PAKcd066141.6e-17170461
STKc_TAOcd066070.0008171462
STKc_PAK1cd066544.3e-07172475
STKc_PAK2cd066551.3e-07172476
STKc_PAK3cd066561e-07172477
STKc_JNK3cd078741.2e-06172522
STKc_STK10_LOKcd066441.1e-07173467
STKc_p38alpha_MAPK14cd078771.4e-06174523
PTKc_Chkcd050833.7e-07175444
STKc_CDK12cd078648.4e-10175448
STKc_CDK9cd078659.5e-10175448
STKc_ASKcd066243.4e-08176448
STKc_MAP4K3cd066458.5e-07176447
STKc_p38beta_MAPK11cd078781.8e-05176496
STKc_p38delta_MAPK13cd078790.00011176493
PKc_MKK7cd066181.2e-09177462
STKc_TNIKcd066378.5e-06177448
STKc_CDK10cd078455.9e-08177467
PTKc_DDR2cd050951.1e-05178457
PTKc_DDR1cd050960.00042178458
PTK_HER3cd051110.00011178435
STKc_p38gamma_MAPK12cd078801.7e-08178529
PTKc_ALK_LTKcd050369.5e-08179434
PTKc_EGFR_likecd050571.3e-05179435
PTKc_FAKcd050561.1e-05179444
PTKc_Tie2cd050885.9e-05179458
STKc_MAP4K5cd066461.2e-06179447
PTK_CCK4cd050460.00016180430
PTKc_Rorcd050481.1e-05180419
PTKc_Trkcd050495.2e-05180434
PTKc_EphR_A2cd050630.00048180452
PTKc_Ror1cd050900.00023180444
PTKc_DDR_likecd050971.8e-06180457
PKc_MEK2cd066491.2e-05180536
PKc_MEK1cd066509.4e-05180540
PTKc_InsR_likecd050324.3e-07181427
PTKc_EphRcd050332.4e-05181424
PTKc_Src_likecd050344e-07181426
PTKc_Jak_rpt2cd050384.3e-08181431
PTK_Rykcd050439.6e-06181432
PTKc_Muskcd050506.1e-06181445
PTKc_Ablcd050524.2e-06181447
PTKc_Tec_likecd050597.4e-05181424
PTKc_InsRcd050611.8e-06181453
PTKc_IGF-1Rcd050621.2e-06181441
PTKc_EphR_Bcd050650.00024181451
PTKc_EphR_Acd050660.0005181452
PTKc_Lck_Blkcd050679.5e-05181453
PTKc_Frk_likecd050686.8e-08181458
PTKc_Yescd050697.4e-07181443
PTKc_Fyn_Yrkcd050706.6e-06181445
PTKc_Srccd050711.4e-05181446
PTKc_Lyncd050726.3e-05181426
PTKc_Hckcd050730.00017181428
PTKc_Jak1_rpt2cd050790.0003181449
PTKc_Tyk2_rpt2cd050804.4e-07181458
PTKc_Cskcd050822.2e-05181446
PTKc_TrkAcd050920.00059181434
PTKc_TrkBcd050930.001181450
PTKc_TrkCcd050940.0004181492
PTKc_Jak2_Jak3_rpt2cd050811.4e-07181460
PTKc_EGFRcd051087.1e-05181473
PTKc_HER2cd051092.5e-05181435
PTKc_Itkcd051124.2e-06181428
PTKc_Btk_Bmxcd051133.3e-06181428
PTKc_Tec_Rlkcd051148.1e-06181446
PKc_MAPKK_Byr1_likecd066203.3e-08181458
STKc_TEY_MAPK_plantcd078585.6e-08181493
STKc_MST1_2cd066129.9e-11182448
STKc_MAP4K3_likecd066133.5e-12182447
PKc_MKK4cd066163.1e-07182478
STKc_MST4cd066408.9e-07182469
STKc_MST3cd066413.9e-07182469
STKc_STK25-YSK1cd066421.1e-07182469
STKc_PCTAIRE_likecd078443.4e-11182483
STKc_Sty1_Hog1cd078565.3e-07182475
STKc_PFTAIRE1cd078698e-06182460
STKc_PFTAIRE2cd078701.6e-07182465
PTKc_Srm_Brkcd051485.4e-06183459
STKc_SLKcd066433.5e-06183465
STKc_MEKK3_like_1cd066534.9e-08183448
STKc_MEKK2cd066528e-06183449
STKc_ERK1_2_likecd078491.3e-07183493
STKc_Nek6_Nek7cd082244.8e-16183444
PTKc_Tie1cd050890.00092184459
STKc_ROCK_NDR_likecd055733.8e-32184532
STKc_phototropin_likcd055741.8e-29184474
STKc_PKAcd055802.2e-55184486
STKc_PDK1cd055812.4e-51184448
STKc_DMPK_likecd055973.3e-42184512
STKc_LATScd055982.3e-17184521
STKc_NDR_likecd055994.5e-15184503
STKc_Sid2p_Dbf2pcd056002e-15184501
STKc_MASTcd056091.1e-36184475
STKc_CRIKcd056013.1e-16184503
STKc_PRKX_likecd056124.7e-47184484
STKc_MRCK_alphacd056234.6e-18184513
STKc_MRCK_betacd056241.1e-22184512
STKc_LATS1cd056251.2e-18184521
STKc_LATS2cd056261.1e-14184527
STKc_NDR2cd056272.2e-10184537
STKc_NDR1cd056287.4e-12184503
STKc_NDR_like_fungalcd056294.3e-24184525
PKc_MAPKKcd066052.5e-11184453
STKc_myosinIII_likecd066081.6e-07184448
STKc_MST3_likecd066094.7e-13184461
PKc_MEKcd066159.4e-10184460
PKc_MKK3_6cd066171.4e-08184462
PKc_MKK5cd066192.9e-05184470
PKc_MAPKK_Pek1_likecd066217e-08184461
PKc_MAPKK_PBS2_likecd066221.7e-08184501
PKc_MAPKK_plant_likecd066231.6e-17184453
STKc_MEKK3_likecd066253.7e-13184448
STKc_NAK1_likecd069178.9e-08184452
STKc_CDKLcd078335.7e-09184448
STKc_CdkB_plantcd078372.1e-12184449
STKc_CDKL1_4cd078472.2e-09184483
STKc_CDKL5cd078484.5e-05184448
STKc_PCTAIRE3cd078711.3e-07184465
STKc_PCTAIRE2cd078721.6e-06184476
STKc_PCTAIRE1cd078733.8e-06184458
STKc_Nek7cd082297.5e-18184446
STKc_Nek6cd082282.8e-18184444
SPS1COG05159.7e-57184573
PTKc_RETcd050451.6e-05185435
PKc_STEcd051227.2e-22185447
STKc_Yank1cd055785.6e-75185448
STKc_MSK_Ncd055838.3e-67185467
STKc_cPKCcd055876.3e-72185513
STKc_GRK4_likecd056051.4e-218185469
STKc_MSK1_Ncd056133.2e-52185467
STKc_MSK2_Ncd056142.1e-50185507
STKc_cPKC_alphacd056153.8e-57185510
STKc_cPKC_betacd056163.8e-56185525
STKc_GRK6cd056301e-255185469
STKc_GRK4cd056313.5e-217185469
STKc_GRK5cd056326.6e-212185469
STKc_MAPKKKcd066062.7e-35185448
STKc_Cdc7_likecd066272.7e-15185448
STKc_MAPKKK_Byr2_likcd066284.1e-17185448
STKc_MEKK1cd066302.8e-10185449
STKc_YSK4cd066314.9e-09185448
STKc_MEKK1_plantcd066329.7e-14185448
STKc_MEKK3cd066512.4e-09185451
STKc_MAPKcd078345.8e-09185495
STKc_Pho85cd078361.6e-13185483
STKc_CDK7cd078412.9e-11185457
STKc_CDK5cd078394.3e-07185448
STKc_NLKcd078531.3e-05185521
STKc_MPK1cd078572e-08185489
STKc_TDY_MAPK_plantcd078593.6e-07185493
STKc_CDK2_3cd078608.2e-11185448
STKc_CDK1_eukcd078614.6e-07185448
STKc_CDK4cd078631.2e-06185448
STKc_BUR1cd078661.4e-10185448
STKc_Nekcd082153.1e-27185448
STKc_Nek1cd082189.5e-24185448
STKc_Nek3cd082195.8e-16185443
STKc_Nek9cd082217.9e-11185448
STKc_Nek11cd082221.7e-08185448
STKc_Nek4cd082232.8e-22185448
STKc_Nek5cd082252.2e-13185448
STKc_Nek8cd082201.2e-09185448
STKc_Nek10cd085284.4e-10185443
STKc_FA2-likecd085292.8e-11185432
STKc_CNK2-likecd085301.3e-13185448
PTKc_Axl_likecd050353.6e-05186447
PTKc_Tyro3cd050740.00011186433
STKc_CMGCcd051189.5e-18186448
STKc_PKNcd055899.2e-60186505
STKc_MAPKKK_Bck1_likcd066291.3e-10186448
STKc_CDK_likecd078291.1e-14186448
STKc_MAK_likecd078301.8e-11186448
STKc_CDK1_likecd078351.2e-08186448
STKc_CDK4_6_likecd078382.7e-09186448
STKc_MAPK4_6cd078545.2e-05186494
STKc_CDK8cd078680.00061186448
STKc_OSR1_SPAKcd066102.7e-12187448
STKc_CDKL2_3cd078462.7e-09187483
STKc_CDK6cd078625.3e-05187474
STKc_MEKK4cd066263.2e-10188448
STKc_CCRKcd078324.8e-15188449
STKc_CDC2L1cd078434.8e-06188448
STKc_CDK8_likecd078428.5e-08188448
STKc_Nek2cd082177.9e-14188448
STKc_RSK_Ncd055822.2e-57189508
STKc_p70S6Kcd055841.7e-59189518
STKc_MOKcd078314.4e-14189448
STKc_CDK9_likecd078403.1e-11189448
PTKccd001921.8e-11190447
PTKc_Ack_likecd050401.4e-07190429
PTKc_Fes_likecd050414.1e-08190426
PTKc_c-roscd050443.2e-05190449
PTKc_Tiecd050470.00074190462
PTKc_Met_Roncd050584.1e-05190462
PTKc_Syk_likecd050601.3e-05190429
PTKc_Fescd050841.5e-07190443
PTKc_Fercd050853.3e-06190429
PTKc_Sykcd051165e-05190449
STKc_PKBcd055716.7e-71190524
STKc_SGKcd055759.6e-59190533
STKc_PKCcd055702.9e-60190500
STKc_aPKCcd055883.2e-54190525
STKc_nPKC_etacd055907.3e-58190506
STKc_nPKC_epsiloncd055919.1e-57190509
STKc_PKB_gammacd055936.4e-49190521
STKc_PKB_alphacd055942.1e-57190521
STKc_PKB_betacd055951.9e-57190518
STKc_SGK1cd056022.8e-43190536
STKc_SGK2cd056034.1e-46190509
STKc_SGK3cd056041.9e-54190535
STKc_nPKC_theta_deltcd055921.5e-61190510
STKc_aPKC_iotacd056184.1e-42190525
STKc_nPKC_thetacd056191e-50190507
STKc_nPKC_deltacd056204.5e-47190507
STKc_aPKC_zetacd056176.9e-49190525
STKc_beta_ARKcd056062.5e-92191468
STKc_GRK3cd056331.8e-91191469
PKccd001804.8e-66192446
PTKc_Zap-70cd051155.4e-05192446
STKc_AGCcd051232.3e-127192448
STKc_cGK_PKGcd055724.8e-56192455
STKc_GRKcd055776.1e-239192468
STKc_MAST_likecd055798.6e-37192453
STKc_YPK1_likecd055851.7e-63192507
STKc_Sck1_likecd055861.4e-49192561
STKc_GRK7cd056073.8e-132192468
STKc_GRK1cd056083.7e-137192468
STKc_SLK_likecd066112.5e-08192462
STKc_Rim15_likecd056118.5e-15194454
STKc_MAPK15cd078523.1e-07237476
RGSpfam006151.1e-3352170
Pkinasepfam000691.2e-78186448
RGSsmart003159.8e-3435170
Pkinase_Tyrpfam077144.7e-14186423
TyrKcsmart002197.5e-14186423
STYKcsmart002211.5e-77186448
S_TKcsmart002204.9e-90196448
S_TK_Xsmart001332.9e-08449528

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
dbSNPrs2230881 Polymorphismp.ARG132GLNN/A
Swiss-ProtVAR_040524Polymorphismp.ARG31GLNN/A
Swiss-ProtVAR_040526Polymorphismp.ILE275METN/A
Swiss-ProtVAR_040525Polymorphismp.THR73METN/A



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