Results for the protein: NP

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
CLECT_CEL-1_like	cd03589	0.00044	406	532
CLECT_DC-SIGN_like	cd03590	1.4e-07	406	532
CLECT_NK_receptors_l	cd03593	3e-05	406	532
CLECT_REG-1_like	cd03594	5.4e-07	406	532
CLECT_EMBP_like	cd03598	0.00011	417	532
CLECT	cd00037	5.9e-19	418	532
CLECT_selectins_like	cd03592	0.00027	418	532
PKD	cd00146	1.2e-07	935	1013
PKD	cd00146	1.7e-24	1022	1122
PKD	cd00146	1.6e-21	1129	1208
PKD	cd00146	7.2e-14	1215	1293
PKD	cd00146	1.3e-12	1297	1376
PKD	cd00146	2.3e-13	1383	1462
PKD	cd00146	2e-16	1468	1544
PKD	cd00146	1.9e-14	1551	1628
PKD	cd00146	6.1e-05	1635	1715
PKD	cd00146	6.4e-13	1722	1798
PKD	cd00146	4.3e-09	1801	1883
PKD	cd00146	1.4e-07	1886	1967
PKD	cd00146	1.2e-17	2063	2143
PLAT	cd00113	1.6e-12	3118	3233
PLAT_polycystin	cd01752	2.3e-72	3118	3237
PLAT_repeat	cd01756	2.4e-28	3118	3237
PLAT_plant_stress	cd01754	8.6e-05	3120	3227
LRRNT	pfam01462	3.3e-06	32	66
LRRCT	pfam01463	0.00073	152	177
WSC	pfam01822	1.7e-07	180	261
PKD	pfam00801	1.5e-10	277	346
Lectin_C	pfam00059	4e-06	425	532
PKD	pfam00801	5.7e-06	855	922
PKD	pfam00801	4.1e-12	937	1007
PKD	pfam00801	2e-27	1024	1116
PKD	pfam00801	3.7e-21	1131	1202
PKD	pfam00801	1.1e-11	1217	1285
PKD	pfam00801	3.6e-11	1301	1370
PKD	pfam00801	6.2e-16	1385	1456
PKD	pfam00801	2.2e-17	1473	1538
PKD	pfam00801	1.1e-18	1553	1622
PKD	pfam00801	1.9e-17	1637	1708
PKD	pfam00801	4.4e-16	1723	1792
PKD	pfam00801	1.8e-15	1807	1877
PKD	pfam00801	3.9e-16	1892	1961
PKD	pfam00801	5.5e-10	1976	2051
PKD	pfam00801	4.7e-20	2066	2135
REJ	pfam02010	1.4e-172	2171	2614
GPS	pfam01825	4.5e-08	3011	3055
PLAT	pfam01477	1.8e-27	3118	3233
LRRNT	smart00013	3.1e-08	32	71
LRR_TYP	smart00369	7.5e-05	90	113
LRR	smart00370	7.5e-05	90	113
LRRCT	smart00082	4e-19	125	177
WSC	smart00321	5.5e-35	177	271
PKD	smart00089	8.7e-09	272	353
CLECT	smart00034	8.7e-23	406	531
PKD	smart00089	6.2e-05	934	1012
PKD	smart00089	2.1e-32	1021	1123
PKD	smart00089	3.8e-21	1128	1209
PKD	smart00089	8.1e-13	1216	1294
PKD	smart00089	2.5e-16	1296	1377
PKD	smart00089	2e-17	1380	1463
PKD	smart00089	4.3e-19	1468	1545
PKD	smart00089	8.3e-18	1550	1629
PKD	smart00089	5.3e-12	1634	1715
PKD	smart00089	1.1e-13	1719	1799
PKD	smart00089	2.5e-16	1802	1884
PKD	smart00089	3.3e-12	1888	1968
PKD	smart00089	2.9e-10	1972	2058
PKD	smart00089	7.7e-23	2059	2142
GPS	smart00303	1.4e-13	3011	3060
LH2	smart00308	2.1e-18	3118	3222
PKD_channel	pfam08016	6.3e-186	3711	4113

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs34197769	Polymorphism	p.ALA3512VAL	N/A
dbSNP	rs3209986	Polymorphism	p.ALA4059VAL	N/A
dbSNP	rs13337123	Polymorphism	p.GLU2966ASP	N/A
dbSNP	rs10960	Polymorphism	p.ILE4045VAL	N/A
dbSNP	rs2549677	Polymorphism	p.MET1092THR	N/A
dbSNP	rs77028972	Polymorphism	p.PHE3066LEU	N/A
dbSNP	rs148709380	Polymorphism	p.THR938MET	N/A
dbSNP	rs116092985	Polymorphism	p.TRP1399ARG	N/A
dbSNP	rs13333553	Polymorphism	p.TRP2882ARG	N/A
dbSNP	rs61747420	Polymorphism	p.VAL3409LEU	N/A
OMIM	601313.0011	Disease	p.ARG324LEU	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0004	Disease	p.ARG4227TER	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0006	Disease	p.CYS4086TER	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0002	Disease	p.GLN1273TER	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0013	Disease	p.GLN1922TER	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0005	Disease	p.GLN3837TER	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0012	Disease	p.LEU845SER	POLYCYSTIC KIDNEY DISEASE 1
OMIM	601313.0015	Disease	p.TRP4139TER	POLYCYSTIC KIDNEY DISEASE 1, SEVERE
OMIM	601313.0007	Disease	p.TYR3818TER	POLYCYSTIC KIDNEY DISEASE 1

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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