Results for the protein: Q8WTQ7

Results for the Protein: Q8WTQ7

21263659

131890

GRK7

NCBI, UniProt

GRK7_HUMAN RecName: Full=G protein-coupled receptor kinase 7; AltName: Full=G protein-coupled receptor kinase GRK7; Flags: Precursor

			0 13 0 2 11

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Swiss-Prot Protein: Q8WTQ7

Identical to: NP_631948

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK2	cd05621	1.3e-12	142	522
STKc_ROCK1	cd05622	4.8e-12	156	520
STKc_TAO1	cd06635	0.00012	162	498
STKc_JNK1	cd07875	1.3e-05	166	501
STKc_PAK5	cd06658	3.8e-06	167	471
STKc_PAK6	cd06659	7.5e-08	167	477
STKc_PAK4	cd06657	3.1e-06	168	473
STKc_JNK2	cd07876	3.5e-07	169	499
STKc_p38alpha_MAPK14	cd07877	6.2e-06	169	514
STKc_myosinIIIB	cd06639	1.8e-05	171	455
STKc_p38beta_MAPK11	cd07878	1.2e-05	171	519
STKc_p38delta_MAPK13	cd07879	6.3e-05	171	514
STKc_p38gamma_MAPK12	cd07880	1.2e-07	171	519
STKc_myosinIIIA	cd06638	1e-05	172	454
STKc_PAK_II	cd06648	2.1e-08	172	467
STKc_PAK1	cd06654	9.7e-06	172	487
STKc_TAO	cd06607	2.5e-05	173	506
STKc_PAK	cd06614	1.6e-12	173	467
STKc_TAO2	cd06634	1.9e-05	173	499
STKc_PAK_I	cd06647	4.1e-05	173	485
STKc_PAK2	cd06655	1.3e-05	173	488
STKc_PAK3	cd06656	6.9e-06	173	491
PTKc_DDR_like	cd05097	0.0008	174	456
PTKc_EGFR_like	cd05057	3.9e-05	175	433
STKc_p38	cd07851	4e-09	175	491
STKc_MAP4K4_6	cd06636	0.00079	177	454
STKc_CDK9	cd07865	5.2e-08	177	454
PTKc_Chk	cd05083	0.00097	178	451
STKc_STK10_LOK	cd06644	1.2e-06	178	474
STKc_MAP4K3	cd06645	2.7e-07	179	449
STKc_MAP4K5	cd06646	2.1e-06	179	453
STKc_JNK3	cd07874	5.9e-07	179	528
STKc_Sty1_Hog1	cd07856	2.2e-06	180	525
STKc_JNK	cd07850	9.6e-08	180	492
PTKc_InsR_like	cd05032	0.00024	181	445
PTKc_Abl	cd05052	0.00026	181	458
PTKc_Yes	cd05069	7.3e-05	181	452
PTKc_Src	cd05071	0.001	181	454
PTKc_Hck	cd05073	0.00021	181	448
STKc_ASK	cd06624	6.4e-09	181	454
STKc_ERK5	cd07855	4.1e-06	181	501
PKc_MKK7	cd06618	4.4e-09	182	468
PKc_MAPKK_Byr1_like	cd06620	1.5e-07	182	459
STKc_CDK10	cd07845	1.2e-06	182	473
PTKc_Ror	cd05048	0.00015	183	408
PTKc_HER2	cd05109	6.3e-05	183	458
STKc_myosinIII_like	cd06608	2e-05	183	419
PTKc_ALK_LTK	cd05036	4.2e-06	184	447
PTKc_Tie2	cd05088	8e-05	184	468
PKc_MEK2	cd06649	1.6e-05	185	537
PKc_MEK1	cd06650	4.4e-05	185	541
STKc_MEKK3	cd06651	2.8e-08	185	456
PTKc_EphR	cd05033	0.0002	186	420
PTKc_Src_like	cd05034	1.8e-05	186	448
PTKc_Jak_rpt2	cd05038	1.7e-07	186	423
PTKc_Csk_like	cd05039	0.00012	186	401
PTKc_InsR	cd05061	0.00023	186	459
PTKc_Lck_Blk	cd05067	0.00025	186	459
PTKc_Frk_like	cd05068	7.5e-07	186	447
PTKc_Fyn_Yrk	cd05070	0.00053	186	451
PTKc_Tyk2_rpt2	cd05080	0.00013	186	453
PTKc_Csk	cd05082	0.00074	186	426
PTKc_Lyn	cd05072	8.9e-06	186	448
PTKc_Btk_Bmx	cd05113	0.00034	186	458
STKc_TNIK	cd06637	4.6e-05	186	454
STKc_ERK1_2_like	cd07849	1.2e-06	186	499
STKc_TEY_MAPK_plant	cd07858	1.1e-07	186	535
STKc_OSR1_SPAK	cd06610	1.7e-08	187	454
STKc_MST1_2	cd06612	1.1e-09	187	412
STKc_MAP4K3_like	cd06613	1.2e-10	187	453
PKc_MKK4	cd06616	3.5e-07	187	472
STKc_MST4	cd06640	7.7e-05	187	474
STKc_MST3	cd06641	5.3e-05	187	480
STKc_SLK	cd06643	2.2e-07	187	472
STKc_STK25-YSK1	cd06642	1.5e-05	187	480
STKc_PCTAIRE_like	cd07844	9.4e-09	187	454
STKc_MAPK4_6	cd07854	3.7e-05	187	487
STKc_CDK12	cd07864	3.1e-07	187	450
STKc_PFTAIRE1	cd07869	5.3e-05	187	468
STKc_PFTAIRE2	cd07870	6.5e-06	187	471
STKc_MEKK3_like_1	cd06653	3.2e-07	188	454
STKc_CDKL	cd07833	5.8e-08	188	454
STKc_CdkB_plant	cd07837	1.2e-12	188	455
STKc_CDKL2_3	cd07846	6.6e-09	188	454
STKc_CDKL1_4	cd07847	1.1e-12	188	489
STKc_ROCK_NDR_like	cd05573	1.1e-19	189	511
STKc_phototropin_lik	cd05574	3.6e-21	189	480
STKc_PDK1	cd05581	2.2e-38	189	454
STKc_PKA	cd05580	1e-39	189	489
STKc_LATS	cd05598	5.8e-13	189	505
STKc_NDR_like	cd05599	7.5e-14	189	509
STKc_CRIK	cd05601	1.8e-16	189	506
STKc_DMPK_like	cd05597	2.8e-40	189	518
STKc_MAST	cd05609	1.1e-38	189	487
STKc_PRKX_like	cd05612	8.1e-38	189	490
STKc_MRCK_alpha	cd05623	3.8e-20	189	519
STKc_MRCK_beta	cd05624	3.8e-24	189	518
STKc_LATS1	cd05625	3.8e-10	189	527
STKc_LATS2	cd05626	2.9e-08	189	531
STKc_NDR2	cd05627	5.9e-09	189	543
STKc_NDR1	cd05628	4.7e-11	189	509
STKc_NDR_like_fungal	cd05629	2.6e-21	189	531
STKc_MST3_like	cd06609	3.3e-11	189	471
PKc_MEK	cd06615	1.7e-09	189	522
PKc_MAPKK	cd06605	2.4e-10	189	459
PKc_MKK3_6	cd06617	1.8e-08	189	465
PKc_MKK5	cd06619	0.00059	189	470
PKc_MAPKK_Pek1_like	cd06621	5.3e-08	189	458
PKc_MAPKK_plant_like	cd06623	1.5e-12	189	459
STKc_NAK1_like	cd06917	2.9e-07	189	463
STKc_CDKL5	cd07848	0.00087	189	471
STKc_CDK6	cd07862	0.00024	189	471
STKc_BUR1	cd07866	5.1e-08	189	454
STKc_PCTAIRE3	cd07871	6.8e-08	189	471
STKc_PCTAIRE2	cd07872	1.9e-06	189	481
STKc_PCTAIRE1	cd07873	5.8e-06	189	461
STKc_Nek8	cd08220	6.7e-07	189	450
STKc_Nek11	cd08222	4.8e-06	189	450
STKc_Nek6_Nek7	cd08224	2.1e-08	189	453
SPS1	COG0515	2e-44	189	550
PKc_STE	cd05122	4.2e-20	190	449
STKc_Yank1	cd05578	1.4e-58	190	454
STKc_MSK_N	cd05583	2.5e-54	190	473
STKc_GRK4_like	cd05605	1.8e-140	190	475
STKc_MSK1_N	cd05613	4.4e-41	190	473
STKc_MSK2_N	cd05614	8e-39	190	513
STKc_cPKC_alpha	cd05615	4.8e-39	190	512
STKc_GRK6	cd05630	1.1e-129	190	475
STKc_GRK5	cd05632	1.2e-139	190	475
STKc_GRK4	cd05631	2e-140	190	475
STKc_MAPKKK	cd06606	2e-28	190	454
STKc_Cdc7_like	cd06627	8.2e-11	190	454
STKc_MAPKKK_Byr2_lik	cd06628	9.2e-09	190	454
STKc_YSK4	cd06631	1.5e-07	190	454
STKc_CCRK	cd07832	1.7e-14	190	451
STKc_MAPK	cd07834	3.7e-08	190	491
STKc_Pho85	cd07836	3.1e-08	190	454
STKc_CDK5	cd07839	1.5e-07	190	454
STKc_CDK7	cd07841	9.5e-11	190	467
STKc_NLK	cd07853	2.5e-06	190	508
STKc_MPK1	cd07857	6e-07	190	492
STKc_TDY_MAPK_plant	cd07859	5.3e-06	190	513
STKc_CDK2_3	cd07860	2e-11	190	454
STKc_CDK1_euk	cd07861	3.8e-11	190	450
STKc_CDK4	cd07863	2.8e-06	190	454
STKc_Nek	cd08215	6.8e-19	190	450
STKc_Nek2	cd08217	8.9e-11	190	444
STKc_Nek1	cd08218	1.2e-10	190	450
STKc_Nek3	cd08219	6.1e-12	190	445
STKc_Nek9	cd08221	6.6e-09	190	450
STKc_Nek4	cd08223	2.5e-19	190	450
STKc_Nek5	cd08225	1.4e-06	190	450
STKc_Nek10	cd08528	1.1e-06	190	446
STKc_CNK2-like	cd08530	4.6e-12	190	443
PTKc_Tyro3	cd05074	0.00042	191	452
PTKc_Jak2_Jak3_rpt2	cd05081	1.7e-05	191	452
STKc_CMGC	cd05118	1.3e-16	191	454
PTKc_Srm_Brk	cd05148	3.9e-06	191	448
STKc_cPKC	cd05587	9.3e-56	191	520
STKc_PKN	cd05589	1.2e-48	191	511
STKc_cPKC_beta	cd05616	1.1e-38	191	516
STKc_CDK_like	cd07829	1.5e-14	191	454
STKc_MAK_like	cd07830	2.7e-14	191	454
STKc_CDK1_like	cd07835	8.2e-09	191	454
STKc_CDK4_6_like	cd07838	1e-08	191	454
STKc_Nek6	cd08228	7.3e-08	191	459
STKc_Nek7	cd08229	5e-10	191	453
STKc_Sid2p_Dbf2p	cd05600	6.6e-15	192	507
PKc_MAPKK_PBS2_like	cd06622	2.3e-08	192	500
STKc_MEKK2	cd06652	1.1e-05	192	455
STKc_CDK8_like	cd07842	2.4e-06	193	454
STKc_CDC2L1	cd07843	5.2e-06	193	454
STKc_FA2-like	cd08529	5.8e-10	193	439
STKc_RSK_N	cd05582	6.1e-42	194	511
STKc_p70S6K	cd05584	2.7e-46	194	513
STKc_MAPKKK_Bck1_lik	cd06629	6.1e-08	194	431
STKc_MOK	cd07831	4.1e-13	194	454
STKc_CDK9_like	cd07840	1.6e-11	194	454
PTKc	cd00192	7.8e-11	195	449
PTKc_Ack_like	cd05040	0.00053	195	421
PTKc_Fes_like	cd05041	1.2e-06	195	414
PTKc_c-ros	cd05044	0.00039	195	450
PTKc_RET	cd05045	0.00011	195	455
PTKc_Syk_like	cd05060	0.00066	195	436
PTKc_Fes	cd05084	1.3e-05	195	464
PTKc_Fer	cd05085	8.2e-05	195	450
PTKc_Syk	cd05116	3.7e-05	195	453
STKc_PKC	cd05570	2.1e-43	195	511
STKc_PKB	cd05571	6.4e-52	195	535
STKc_SGK	cd05575	1.3e-47	195	511
STKc_aPKC	cd05588	7.1e-42	195	523
STKc_nPKC_eta	cd05590	2.6e-56	195	512
STKc_nPKC_epsilon	cd05591	2.4e-50	195	512
STKc_nPKC_theta_delt	cd05592	1.8e-51	195	513
STKc_PKB_gamma	cd05593	3.7e-28	195	516
STKc_PKB_alpha	cd05594	1.5e-32	195	525
STKc_PKB_beta	cd05595	2.9e-38	195	513
STKc_SGK1	cd05602	2e-33	195	533
STKc_SGK2	cd05603	4e-38	195	512
STKc_SGK3	cd05604	7.8e-39	195	511
STKc_aPKC_zeta	cd05617	7.6e-35	195	516
STKc_aPKC_iota	cd05618	7.6e-32	195	516
STKc_nPKC_theta	cd05619	3.3e-47	195	513
STKc_nPKC_delta	cd05620	3e-41	195	513
STKc_MEKK3_like	cd06625	1e-12	195	454
STKc_MEKK4	cd06626	2.1e-08	195	454
STKc_MEKK1	cd06630	1.6e-07	195	420
STKc_MEKK1_plant	cd06632	3.9e-11	195	454
STKc_beta_ARK	cd05606	4.5e-76	196	474
STKc_GRK3	cd05633	1.4e-63	196	475
PKc	cd00180	1.2e-62	197	448
PTKc_Zap-70	cd05115	3.3e-05	197	453
STKc_AGC	cd05123	2.7e-95	197	454
STKc_cGK_PKG	cd05572	5.8e-34	197	461
STKc_GRK	cd05577	2.7e-232	197	474
STKc_MAST_like	cd05579	5.6e-25	197	459
STKc_YPK1_like	cd05585	3.4e-58	197	510
STKc_Sck1_like	cd05586	8.6e-41	197	551
STKc_GRK7	cd05607	6.4e-231	197	474
STKc_GRK1	cd05608	7.8e-126	197	474
STKc_SLK_like	cd06611	1.5e-07	197	468
STKc_Rim15_like	cd05611	2.8e-11	199	460
STKc_MAPK15	cd07852	7.8e-06	238	482
RGS	pfam00615	3.5e-09	55	175
Pkinase	pfam00069	2.2e-66	191	454
RGS	smart00315	2.1e-17	55	175
Pkinase_Tyr	pfam07714	1.7e-13	191	454
TyrKc	smart00219	2.9e-13	191	448
STYKc	smart00221	4.2e-67	191	454
S_TKc	smart00220	1.6e-80	201	454

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_051624	Polymorphism	p.ARG461CYS	N/A
Swiss-Prot	VAR_040527	Polymorphism	p.ARG81HIS	N/A
Swiss-Prot	VAR_040533	Polymorphism	p.ARG226TRP	N/A
Swiss-Prot	VAR_040528	Polymorphism	p.CYS113TRP	N/A
Swiss-Prot	VAR_040535	Polymorphism	p.GLU309GLN	N/A
dbSNP	rs36009541	Polymorphism	p.GLU443GLY	N/A
dbSNP	rs33928105	Polymorphism	p.PRO460THR	N/A
Swiss-Prot	VAR_040529	Polymorphism	p.SER115CYS	N/A
Swiss-Prot	VAR_040534	Polymorphism	p.SER253PHE	N/A
Swiss-Prot	VAR_040530	Polymorphism	p.SER127THR	N/A
Swiss-Prot	VAR_040531	Polymorphism	p.VAL196GLY	N/A
Swiss-Prot	VAR_040536	Polymorphism	p.VAL313ILE	N/A
Swiss-Prot	VAR_040532	Polymorphism	p.VAL196MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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