Home News About DMDM Database Statistics Research Publications Contact  

Results for the Protein: Q16832
215273969

DDR2_HUMAN RecName: Full=Discoidin domain-containing receptor 2; Short=Discoidin domain receptor 2; AltName: Full=CD167 antigen-like family member B; AltName: Full=Discoidin domain-containing receptor tyrosine kinase 2; AltName: Full=Neurotrophic tyrosine kinase, receptor-related 3; AltName: Full=Receptor protein-tyrosine kinase TKT; AltName: Full=Tyrosine-protein kinase TYRO10; AltName: CD_antigen=CD167b; Flags: Precursor

Known Diseases associated with this Protein:
  SPONDYLOEPIMETAPHYSEAL DYSPLASIA SHORT LIMB-HAND TYPE (SEMD-SL)
  SPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
8
4
4
0
8
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

FA58C - smart00231
FA58C - cd00057
F5_F8_type_C - pfam00754
PTKc_CSF-1R - cd05106
PTKc_PDGFR_beta - cd05107
PTKc_PDGFR_alpha - cd05105
PTKc_Kit - cd05104
PTKc_PDGFR - cd05055
STKc_PAK - cd06614
STKc_TAO1 - cd06635
STKc_PAK6 - cd06659
PTKc_FGFR1 - cd05098
STKc_TAO2 - cd06634
STKc_CDK10 - cd07845
STKc_PAK_II - cd06648
STKc_CDK12 - cd07864
STKc_CDK9 - cd07865
PTKc_FGFR2 - cd05101
STKc_p38 - cd07851
PTK_Ryk - cd05043
PTKc_FGFR4 - cd05099
PTK_HER3 - cd05111
PTKc_EGFR_like - cd05057
PTKc_ALK_LTK - cd05036
PTKc_FAK - cd05056
PTKc_TrkC - cd05094
PTKc_DDR2 - cd05095
PTKc_TrkB - cd05093
PTKc_Ror2 - cd05091
PTKc_Csk - cd05082
PTKc_Ror1 - cd05090
PTKc_DDR_like - cd05097
PTKc_TrkA - cd05092
PTKc_VEGFR3 - cd05102
STKc_SLK_like - cd06611
PTKc_Hck - cd05073
PTKc_VEGFR - cd05054
PTKc_Srm_Brk - cd05148
PTKc_VEGFR2 - cd05103
PTKc_DDR1 - cd05096
PTKc_FGFR3 - cd05100
PTKc_Csk_like - cd05039
PTKc_Musk - cd05050
PTKc_DDR - cd05051
PTKc_Abl - cd05052
PTKc_Trk - cd05049
PTKc_Ror - cd05048
PTKc_Lyn - cd05072
PTK_CCK4 - cd05046
PTKc_InsR_like - cd05032
PTKc_InsR - cd05061
PTKc_FGFR - cd05053
PTKc_IGF-1R - cd05062
PTKc_Fyn_Yrk - cd05070
PTKc_Src_like - cd05034
PTKc_Src - cd05071
PTKc_Frk_like - cd05068
PTKc_Yes - cd05069
PTKc_Lck_Blk - cd05067
PTKc_EphR_A2 - cd05063
PTKc_EphR_A10 - cd05064
PTKc_Chk - cd05083
PTKc_Tie2 - cd05088
PTKc_Tec_Rlk - cd05114
PTKc_Btk_Bmx - cd05113
PTKc_Itk - cd05112
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_EphR - cd05033
PTKc_Tyk2_rpt2 - cd05080
PTKc_Jak_rpt2 - cd05038
PTKc_Tec_like - cd05059
PTKc_Jak1_rpt2 - cd05079
PTKc_EphR_A - cd05066
STKc_STK25-YSK1 - cd06642
STKc_MST3 - cd06641
STKc_MEKK3_like_1 - cd06653
STKc_MST4 - cd06640
STKc_MST1_2 - cd06612
STKc_MAP4K3_like - cd06613
PKc_MAPKK_Byr1_like - cd06620
STKc_Nek6_Nek7 - cd08224
STKc_Nek11 - cd08222
STKc_BUR1 - cd07866
STKc_CDKL1_4 - cd07847
STKc_PCTAIRE3 - cd07871
SPS1 - COG0515
STKc_NAK1_like - cd06917
STKc_PCTAIRE1 - cd07873
STKc_PCTAIRE2 - cd07872
STKc_Nek1 - cd08218
STKc_PRKX_like - cd05612
PTKc_EGFR - cd05108
PKc_MAPKK_plant_like - cd06623
STKc_PKA - cd05580
PKc_MAPKK - cd06605
STKc_MST3_like - cd06609
PKc_MAPKK_Pek1_like - cd06621
PKc_MKK3_6 - cd06617
PKc_MKK5 - cd06619
PKc_MEK - cd06615
STKc_Nek4 - cd08223
STKc_Nek6 - cd08228
STKc_MPK1 - cd07857
STKc_Nek7 - cd08229
STKc_CDK8_like - cd07842
STKc_MAPKKK - cd06606
PKc_STE - cd05122
STKc_Cdc7_like - cd06627
STKc_YSK4 - cd06631
PTKc_RET - cd05045
STKc_CDK_like - cd07829
Pkinase - pfam00069
Pkinase_Tyr - pfam07714
STYKc - smart00221
TyrKc - smart00219
STKc_CDK1_euk - cd07861
STKc_MAK_like - cd07830
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
PTKc_Axl - cd05075
PTKc_Tie1 - cd05089
STKc_MEKK3 - cd06651
STKc_phototropin_lik - cd05574
STKc_CDK1_like - cd07835
STKc_CNK2-like - cd08530
STKc_GRK5 - cd05632
STKc_Nek10 - cd08528
STKc_CDK7 - cd07841
STKc_GRK6 - cd05630
STKc_GRK4 - cd05631
STKc_GRK4_like - cd05605
STKc_CDK2_3 - cd07860
STKc_CCRK - cd07832
STKc_MAPKKK_Bck1_lik - cd06629
STKc_MAPKKK_Byr2_lik - cd06628
STKc_PDK1 - cd05581
STKc_CDK4_6_like - cd07838
STKc_OSR1_SPAK - cd06610
STKc_FA2-like - cd08529
STKc_CDK9_like - cd07840
STKc_Nek - cd08215
STKc_MEKK4 - cd06626
STKc_Nek2 - cd08217
STKc_MEKK1_plant - cd06632
STKc_MOK - cd07831
STKc_PKC - cd05570
STKc_CMGC - cd05118
STKc_CDKL - cd07833
STKc_CDKL2_3 - cd07846
PTKc_Syk - cd05116
STKc_Nek8 - cd08220
STKc_CDK5 - cd07839
STKc_CdkB_plant - cd07837
PTKc_Ack_like - cd05040
PTKc_Tie - cd05047
PTKc_Aatyk - cd05042
PTKc_Fes_like - cd05041
PTK_Jak_rpt1 - cd05037
PTKc_Aatyk1_Aatyk3 - cd05087
PTKc - cd00192
PTKc_c-ros - cd05044
PTKc_Met_Ron - cd05058
PTKc_Fes - cd05084
PTKc_Fer - cd05085
PTKc_Aatyk2 - cd05086
PTK_Jak2_Jak3_rpt1 - cd05078
PTK_Jak1_rpt1 - cd05077
PTKc_Syk_like - cd05060
PTK_Tyk2_rpt1 - cd05076
PTKc_Zap-70 - cd05115
STKc_Nek9 - cd08221
STKc_AGC - cd05123
PTKc_HER4 - cd05110
PKc - cd00180
STKc_cGK_PKG - cd05572
STKc_GRK - cd05577
STKc_GRK1 - cd05608
STKc_MAST_like - cd05579
STKc_MEKK3_like - cd06625
STKc_ASK - cd06624
STKc_CDK4 - cd07863
PTKc_HER2 - cd05109
PTKc_EphR_B - cd05065
S_TKc - smart00220
STKc_PCTAIRE_like - cd07844
STKc_PFTAIRE2 - cd07870
STKc_Nek3 - cd08219
PKc_MAPKK_PBS2_like - cd06622
STKc_CDC2L1 - cd07843
STKc_Pho85 - cd07836
STKc_MEKK1 - cd06630
STKc_MAPK - cd07834
STKc_Yank1 - cd05578


Swiss-Prot Protein: Q16832
Identical to: NP_006173, NP_001014796
   Default View:
































































































































































































Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
FA58Ccd000572.9e-6732184
PTKc_CSF-1Rcd051064.5e-24518854
PTKc_PDGFR_alphacd051054.4e-14521852
PTKc_PDGFR_betacd051078.1e-10521854
PTKc_Kitcd051041.8e-14522853
PTKc_PDGFRcd050559.2e-19538853
STKc_PAKcd066142.5e-10541852
STKc_TAO1cd066350.00077542851
STKc_PAK6cd066590.00028543854
PTKc_FGFR1cd050983e-43548855
STKc_TAO2cd066340.00064550852
STKc_CDK10cd078451.2e-06550843
STKc_PAK_IIcd066483.7e-05551855
STKc_CDK12cd078641.1e-07551847
PTKc_FGFR2cd051012.3e-45552855
STKc_p38cd078510.00032552844
STKc_CDK9cd078651.5e-05552842
PTK_Rykcd050433.5e-24553849
PTKc_FGFR4cd050994.8e-42554855
PTKc_EGFR_likecd050571.3e-45555851
PTK_HER3cd051112.1e-25555851
PTKc_ALK_LTKcd050362e-67556852
PTKc_FAKcd050562.5e-63556855
PTKc_Src_likecd050342e-60557852
PTKc_InsR_likecd050323.7e-79557851
PTK_CCK4cd050461.5e-64557851
PTKc_Rorcd050481.6e-88557852
PTKc_Trkcd050491.1e-108557851
PTKc_Muskcd050501.7e-93557851
PTKc_DDRcd050513.8e-227557851
PTKc_Ablcd050523.3e-68557853
PTKc_FGFRcd050534.4e-55557849
PTKc_InsRcd050611.1e-55557855
PTKc_IGF-1Rcd050627.6e-63557851
PTKc_EphR_A2cd050632e-56557853
PTKc_EphR_A10cd050641.6e-47557853
PTKc_Lck_Blkcd050671e-44557852
PTKc_Frk_likecd050689.7e-71557852
PTKc_Yescd050699.5e-41557852
PTKc_Fyn_Yrkcd050703.2e-47557852
PTKc_Srccd050712.3e-42557854
PTKc_Lyncd050721.6e-36557852
PTKc_Hckcd050739.8e-39557852
PTKc_Cskcd050825.6e-35557852
PTKc_Csk_likecd050391.8e-23557852
PTKc_Ror1cd050908.1e-69557852
PTKc_Ror2cd050916.9e-61557852
PTKc_TrkAcd050923.4e-88557851
PTKc_TrkBcd050931.5e-82557854
PTKc_TrkCcd050941.3e-65557854
PTKc_DDR2cd050952.3e-238557851
PTKc_DDR_likecd050979.3e-203557851
PTKc_FGFR3cd051001.1e-29557855
PTKc_VEGFR3cd051022.2e-23557854
PTKc_VEGFR2cd051032.3e-14557854
PTKc_DDR1cd050967.9e-185557851
PTKc_Srm_Brkcd051485e-49557852
PTKc_VEGFRcd050542.1e-16557853
STKc_SLK_likecd066117.2e-06557851
PTKc_Jak_rpt2cd050382.1e-60558853
PTKc_EphRcd050331e-68558853
PTKc_Tec_likecd050595.8e-45558850
PTKc_EphR_Acd050668.8e-59558853
PTKc_Jak1_rpt2cd050791.6e-37558849
PTKc_Tyk2_rpt2cd050808.7e-28558854
PTKc_Jak2_Jak3_rpt2cd050813.6e-41558853
PTKc_Chkcd050837.9e-39558852
PTKc_Tie2cd050882.1e-29558855
PTKc_Itkcd051127.4e-47558850
PTKc_Btk_Bmxcd051133.5e-53558850
PTKc_Tec_Rlkcd051142.3e-49558850
STKc_MST1_2cd066126.5e-07559845
STKc_MAP4K3_likecd066131.7e-07559854
PKc_MAPKK_Byr1_likecd066200.00027559855
STKc_MST4cd066400.00064559853
STKc_MST3cd066410.00024559855
STKc_STK25-YSK1cd066420.00012559853
STKc_MEKK3_like_1cd066530.00031559851
STKc_Nek11cd082222.2e-06560851
STKc_Nek6_Nek7cd082244.4e-07560854
PTKc_EGFRcd051081.2e-13561855
STKc_PKAcd055800.00046561825
STKc_PRKX_likecd056129.6e-05561843
STKc_MST3_likecd066095.5e-07561826
PKc_MAPKKcd066056.8e-08561855
PKc_MEKcd066150.00047561854
PKc_MKK3_6cd066170.00015561848
PKc_MKK5cd066199.8e-05561855
PKc_MAPKK_Pek1_likecd066213.2e-05561832
PKc_MAPKK_plant_likecd066234.1e-10561855
STKc_NAK1_likecd069175.2e-05561850
STKc_CDKL1_4cd078471.9e-05561851
STKc_BUR1cd078662.3e-06561805
STKc_PCTAIRE3cd078714e-06561852
STKc_PCTAIRE2cd078722.1e-05561851
STKc_PCTAIRE1cd078730.00035561854
STKc_Nek1cd082187e-05561851
SPS1COG05150.00081561855
PTKc_RETcd050453e-35562852
PKc_STEcd051222.9e-10562853
STKc_MAPKKKcd066064.8e-16562849
STKc_Cdc7_likecd066273.6e-12562849
STKc_YSK4cd066311.4e-07562849
STKc_CDK8_likecd078421.8e-06562842
STKc_MPK1cd078570.00013562853
STKc_Nek4cd082230.00063562851
STKc_Nek6cd082287.6e-06562835
STKc_Nek7cd082292.5e-06562854
PTKc_Axl_likecd050356.7e-59563853
PTKc_Tyro3cd050741.7e-54563853
PTKc_Axlcd050754.1e-47563853
PTKc_Tie1cd050891.1e-28563855
STKc_phototropin_likcd055740.00026563855
STKc_MEKK3cd066511.3e-05563853
STKc_MAK_likecd078303.6e-10563849
STKc_CDK1_likecd078351.2e-05563849
STKc_CDK1_eukcd078610.0004563849
STKc_CDK_likecd078293.1e-12563842
STKc_GRK4_likecd056053.7e-06564855
STKc_GRK4cd056310.00024564855
STKc_GRK6cd056300.00036564855
STKc_GRK5cd056329.1e-05564855
STKc_CCRKcd078325.2e-07564843
STKc_CDK7cd078415.6e-10564851
STKc_CDK2_3cd078606.9e-05564849
STKc_Nek10cd085280.00091564851
STKc_CNK2-likecd085308e-06564849
STKc_PDK1cd055813.8e-11565849
STKc_OSR1_SPAKcd066103.2e-06565849
STKc_MAPKKK_Byr2_likcd066283.4e-07565851
STKc_MAPKKK_Bck1_likcd066291.2e-06565843
STKc_CDK4_6_likecd078380.00012565842
STKc_FA2-likecd085291.7e-05565854
STKc_MEKK4cd066262.3e-08566845
STKc_CDK9_likecd078403.2e-08566805
STKc_Nekcd082153.4e-13566851
STKc_Nek2cd082173.1e-05566849
PTKccd001926.9e-144567850
PTK_Jak_rpt1cd050372.7e-10567850
PTKc_Fes_likecd050413.5e-47567851
PTKc_Aatykcd050421.9e-29567851
PTKc_Ack_likecd050408.7e-59567851
PTKc_c-roscd050441.8e-69567851
PTKc_Tiecd050474.9e-40567854
PTKc_Met_Roncd050587.1e-58567855
PTKc_Syk_likecd050601.6e-59567854
PTK_Tyk2_rpt1cd050761.4e-05567850
PTK_Jak1_rpt1cd050776.4e-09567850
PTK_Jak2_Jak3_rpt1cd050782.7e-08567850
PTKc_Fescd050842e-51567851
PTKc_Fercd050852.3e-45567851
PTKc_Aatyk2cd050865.7e-34567851
PTKc_Aatyk1_Aatyk3cd050872.8e-44567851
PTKc_Sykcd051163.5e-44567854
STKc_CMGCcd051182.5e-09567842
STKc_PKCcd055700.00016567848
STKc_MEKK1_plantcd066324.3e-08567845
STKc_MOKcd078310.00029567842
STKc_CDKLcd078332.8e-05567849
STKc_CdkB_plantcd078373.9e-06567851
STKc_CDK5cd078395.9e-05567847
STKc_CDKL2_3cd078464.6e-05567849
STKc_Nek8cd082201.2e-05567849
PTKc_Zap-70cd051155.2e-46568854
PKccd001801.3e-59569849
PTKc_HER4cd051105e-12569854
STKc_AGCcd051231.4e-09569849
STKc_cGK_PKGcd055729.7e-08569849
STKc_GRKcd055775.2e-05569854
STKc_MAST_likecd055791.7e-08569847
STKc_GRK1cd056085.4e-05569854
STKc_MEKK3_likecd066258.6e-09569855
STKc_Nek9cd082216.9e-06569849
STKc_ASKcd066241.5e-05571848
PTKc_EphR_Bcd050657.1e-55573853
PTKc_HER2cd051096.7e-27573851
STKc_CDK4cd078636e-05573849
STKc_PCTAIRE_likecd078444.4e-05574850
STKc_PFTAIRE2cd078700.00079574849
STKc_Nek3cd082191e-06576851
PKc_MAPKK_PBS2_likecd066220.00011580840
STKc_CDC2L1cd078436.6e-06580805
STKc_MEKK1cd066309.2e-05581850
STKc_Pho85cd078361.9e-05581855
STKc_MAPKcd078342.1e-06587852
STKc_Yank1cd055780.00054592849
F5_F8_type_Cpfam007543.2e-3145182
Pkinasepfam000693.5e-36563849
FA58Csmart002312.5e-5629185
Pkinase_Tyrpfam077142.7e-118563849
TyrKcsmart002192.2e-140563849
STYKcsmart002214e-52563822
S_TKcsmart002206.1e-37573849

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_041500Polymorphismp.ARG478CYSN/A
Swiss-ProtVAR_063052Diseasep.ARG752CYSSpondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL)
Swiss-ProtVAR_041498Polymorphismp.ARG105SERN/A
Swiss-ProtVAR_065719Diseasep.GLU113LYSSpondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL)
Swiss-ProtVAR_063051Diseasep.ILE726ARGSpondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL)
Swiss-ProtVAR_041499Polymorphismp.MET441ILEN/A
Swiss-ProtVAR_063050Diseasep.THR713ILESpondyloepimetaphyseal dysplasia short limb-hand type (SEMD-SL)
Swiss-ProtVAR_041501Polymorphismp.VAL543PHEN/A
OMIM191311.0001 Diseasep.ARG752CYSSPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
OMIM191311.0005 Diseasep.GLU113LYSSPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
OMIM191311.0002 Diseasep.ILE726ARGSPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE
OMIM191311.0003 Diseasep.THR713ILESPONDYLOMETAEPIPHYSEAL DYSPLASIA, SHORT LIMB-HAND TYPE



   |   1000 Hilltop Circle, Baltimore, MD 21250   |   Department of Biological Sciences   |   Phone: 410-455-2258