Results for the protein: NP

Results for the Protein: NP_036441

226817313

22941

SHANK2

NCBI

SH3 and multiple ankyrin repeat domains protein 2 isoform 1 [Homo sapiens]

Known Diseases associated with this Protein:
AUTISM, SUSCEPTIBILITY TO, 17

1

3

1

3

0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: Arp - COG0666 ANK - cd00204 Ank - pfam00023 ANK - smart00248 SH3 - smart00326 SH3_2 - pfam07653 SH3 - cd00174 SH3_1 - pfam00018 PDZ - smart00228 PDZ_signaling - cd00992 PDZ - pfam00595 PDZ - cd00136 SAM - smart00454 SAM_2 - pfam07647 SAM_1 - pfam00536 - cd00166	RefSeq Protein: NP_036441 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ANK	cd00204	8.5e-19	163	285
ANK	cd00204	2e-17	292	418
SH3	cd00174	2.6e-15	530	582
PDZ_signaling	cd00992	1.6e-24	624	717
PDZ	cd00136	0.00026	635	717
	cd00166	6.5e-23	1785	1847
Ank	pfam00023	1.2e-05	230	262
Ank	pfam00023	0.00075	330	362
SH3_1	pfam00018	4e-06	532	577
PDZ	pfam00595	2.2e-05	626	717
SAM_1	pfam00536	1.2e-24	1784	1847
ANK	smart00248	0.00018	230	259
ANK	smart00248	0.00063	330	359
SH3	smart00326	6.3e-16	527	583
SH3_2	pfam07653	9.2e-12	530	582
PDZ	smart00228	5.8e-27	623	720
SAM_2	pfam07647	1.1e-20	1783	1847
SAM	smart00454	2.5e-24	1783	1849

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs7926203	Polymorphism	p.ARG174CYS	N/A
dbSNP	rs11237599	Polymorphism	p.VAL336ILE	N/A
dbSNP	rs73521173	Polymorphism	p.VAL129MET	N/A
OMIM	603290.0003	Disease	p.ARG462TER	AUTISM, SUSCEPTIBILITY TO, 17

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