Results for the protein: NP

Results for the Protein: NP_690621

22902130

5754

PTK7

NCBI

inactive tyrosine-protein kinase 7 isoform d precursor [Homo sapiens]

			0 3 0 3 0

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RefSeq Protein: NP_690621

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Ig4_L1-NrCAM_like	cd04978	0.00057	46	122
Ig	cd00096	1.6e-07	49	116
Ig1_Contactin	cd04967	0.00049	127	215
Ig1_Robo	cd07693	1.2e-05	127	220
Ig2_FGFR_like	cd05729	3e-05	135	219
Ig2_FGFRL1-like	cd05856	0.00063	136	217
Ig4_Neogenin	cd05723	0.00094	145	217
Ig	cd00096	1.1e-11	146	214
Ig6_L1-CAM_like	cd05733	0.00061	146	217
Ig4_Peroxidasin	cd05746	1.5e-06	146	216
Ig2_PTK7	cd05760	4.8e-55	146	222
Ig1_Neogenin	cd05722	7.2e-05	226	319
Ig	cd00096	8.8e-06	242	316
Ig2_Robo	cd05724	4.9e-08	328	408
Ig2_FGFR_like	cd05729	0.00024	330	406
Ig	cd00096	1.4e-07	339	405
Ig3_L1-CAM	cd05876	0.00054	341	409
Ig1_Neogenin	cd05722	0.00028	413	498
Ig4_Contactin-2-like	cd05728	4.8e-06	413	498
Ig2_FGFR_like	cd05729	0.0003	418	498
Ig3_Peroxidasin	cd05745	7.7e-09	425	498
Ig5_Contactin_like	cd04969	0.00021	426	498
Ig4_Robo	cd05726	1.8e-05	426	507
Ig_2	cd05764	2.6e-05	426	498
Ig	cd00096	3.2e-07	429	495
Ig3_Robo	cd05725	0.00077	429	498
Ig4_Peroxidasin	cd05746	5e-06	430	497
Ig3_Contactin_like	cd04968	2.3e-05	506	589
Ig4_L1-NrCAM_like	cd04978	0.00049	517	589
Ig2_FGFR_like	cd05729	0.00018	517	588
Ig3_Peroxidasin	cd05745	0.00031	518	588
Ig_2	cd05764	0.0001	519	588
Ig	cd00096	6.6e-14	520	585
Ig3_Robo	cd05725	4.7e-05	520	588
Ig4_Peroxidasin	cd05746	9.7e-05	520	587
Ig_1	cd05763	3.2e-05	520	589
Ig3_L1-CAM	cd05876	5.3e-06	520	589
Ig3_L1-CAM_like	cd05731	6.8e-06	524	589
PTKc_CSF-1R	cd05106	3.2e-26	702	1010
PTKc_Kit	cd05104	6e-14	705	1009
PTKc_PDGFR_alpha	cd05105	1.2e-12	705	1008
PTKc_PDGFR_beta	cd05107	9.3e-10	705	1010
STKc_myosinIIIB	cd06639	7.2e-05	719	1011
PTKc_FGFR1	cd05098	3e-38	721	1013
STKc_myosinIIIA	cd06638	2.2e-05	721	1010
STKc_PAK	cd06614	9.7e-07	722	1014
STKc_PAK6	cd06659	0.00096	722	1014
PTKc_FGFR2	cd05101	8.9e-40	724	1012
PTK_Tyk2_rpt1	cd05076	2.3e-06	725	1006
PTKc_PDGFR	cd05055	8.4e-18	727	1009
PTKc_FGFR4	cd05099	9.7e-43	727	1012
PTKc_FGFR3	cd05100	1.9e-30	727	1014
STKc_TAO2	cd06634	0.00078	727	1008
STKc_ASK	cd06624	4.7e-07	731	1010
STKc_PAK_II	cd06648	0.00025	731	1014
STKc_CDK9	cd07865	5.6e-05	731	998
PTKc_VEGFR	cd05054	3e-26	732	1012
PTKc_EGFR_like	cd05057	7.3e-43	732	1013
PTKc_VEGFR2	cd05103	3e-26	732	1012
PTKc_VEGFR3	cd05102	1.6e-29	732	1012
PTKc_ALK_LTK	cd05036	5.7e-79	733	1007
PTKc_Csk_like	cd05039	2.1e-24	733	1008
PTKc_Abl	cd05052	2.8e-60	733	1009
PTKc_FAK	cd05056	2.3e-55	733	1013
PTKc_InsR	cd05061	3.3e-48	733	1014
PTKc_IGF-1R	cd05062	4.2e-55	733	1007
PTKc_Lck_Blk	cd05067	2.5e-45	733	1008
PTKc_Frk_like	cd05068	5e-64	733	1008
PTKc_Yes	cd05069	3.7e-40	733	1008
PTKc_Fyn_Yrk	cd05070	1.1e-39	733	1008
PTKc_Src	cd05071	2.3e-38	733	1010
PTKc_Lyn	cd05072	2.9e-43	733	1008
PTKc_Csk	cd05082	1.5e-44	733	1008
PTKc_Hck	cd05073	6e-43	733	1008
PTKc_HER2	cd05109	3.2e-23	733	1013
STKc_STK10_LOK	cd06644	0.00027	733	1013
PTK_CCK4	cd05046	2.3e-209	734	1007
PTKc_Ror	cd05048	5.6e-71	734	1008
PTKc_Trk	cd05049	2.8e-68	734	1007
PTKc_Musk	cd05050	3.1e-76	734	1007
PTKc_DDR	cd05051	2.4e-67	734	1007
PTKc_EphR_A2	cd05063	1.9e-47	734	1009
PTKc_EphR_A10	cd05064	9.8e-44	734	1009
PTKc_Ror1	cd05090	3.8e-56	734	1008
PTKc_Ror2	cd05091	1.7e-51	734	1008
PTKc_TrkA	cd05092	1.8e-62	734	1007
PTKc_TrkB	cd05093	1.4e-51	734	1013
PTKc_TrkC	cd05094	1.1e-38	734	1011
PTKc_DDR2	cd05095	2.8e-60	734	1007
PTKc_DDR1	cd05096	1.1e-46	734	1007
PTKc_DDR_like	cd05097	4.5e-60	734	1007
STKc_SLK	cd06643	6.5e-06	734	1014
STKc_PCTAIRE_like	cd07844	0.00056	734	1010
PTKc_InsR_like	cd05032	7.9e-67	735	1007
PTKc_EphR	cd05033	3.3e-49	735	1009
PTKc_Jak_rpt2	cd05038	1.9e-47	735	1009
PTKc_FGFR	cd05053	8.6e-43	735	1011
PTKc_Tec_like	cd05059	3.2e-41	735	1006
PTKc_EphR_B	cd05065	1.7e-43	735	1010
PTKc_EphR_A	cd05066	8.1e-46	735	1010
PTKc_Jak1_rpt2	cd05079	6.7e-36	735	1009
PTKc_Tyk2_rpt2	cd05080	4.8e-24	735	1010
PTKc_Jak2_Jak3_rpt2	cd05081	8e-48	735	1009
PTKc_Tie2	cd05088	2e-27	735	1012
PTKc_EGFR	cd05108	7.1e-12	735	1014
PTKc_HER4	cd05110	1.1e-10	735	1013
PTK_HER3	cd05111	1.3e-28	735	1013
PTKc_Itk	cd05112	2.3e-57	735	1006
PTKc_Btk_Bmx	cd05113	6.4e-54	735	1006
PTKc_Tec_Rlk	cd05114	1.4e-56	735	1006
PTKc_Src_like	cd05034	1.2e-53	736	1008
PTK_Ryk	cd05043	3.3e-33	736	1010
PTKc_Srm_Brk	cd05148	3.7e-41	736	1008
STKc_myosinIII_like	cd06608	0.00019	736	1001
STKc_SLK_like	cd06611	3.8e-06	736	1011
STKc_MST1_2	cd06612	1.6e-05	736	1001
STKc_MAP4K3_like	cd06613	5e-09	736	1006
STKc_MST4	cd06640	0.00019	736	1013
STKc_MST3	cd06641	9.2e-05	736	1013
STKc_STK25-YSK1	cd06642	2.9e-05	736	1013
STKc_MEKK3_like_1	cd06653	0.00024	737	1007
STKc_Nek11	cd08222	6e-07	737	1010
STKc_Nek6_Nek7	cd08224	2.1e-07	737	1010
PTKc_Tie1	cd05089	8.5e-27	738	1011
STKc_phototropin_lik	cd05574	0.00034	738	1011
STKc_PRKX_like	cd05612	0.00031	738	1014
PKc_MAPKK	cd06605	2.8e-05	738	1003
STKc_MST3_like	cd06609	1.6e-05	738	1013
PKc_MAPKK_Byr1_like	cd06620	1.9e-05	738	1013
PKc_MAPKK_plant_like	cd06623	3.9e-10	738	1006
STKc_NAK1_like	cd06917	6.8e-06	738	1013
STKc_CdkB_plant	cd07837	2.8e-07	738	1011
STKc_CDK10	cd07845	6.8e-06	738	1014
STKc_CDKL2_3	cd07846	8.5e-05	738	1006
STKc_CDKL1_4	cd07847	2.4e-05	738	1007
STKc_CDK6	cd07862	0.0001	738	1010
STKc_CDK12	cd07864	7.5e-06	738	1014
STKc_Nek6	cd08228	2.8e-08	738	1010
STKc_Nek7	cd08229	2e-09	738	1007
PTKc_RET	cd05045	1.9e-48	739	1012
PTKc_Chk	cd05083	2.4e-42	739	1008
PKc_STE	cd05122	1.4e-10	739	998
STKc_MSK_N	cd05583	0.00095	739	1014
STKc_GRK4_like	cd05605	9.7e-05	739	1014
STKc_MSK1_N	cd05613	0.00078	739	1014
STKc_MAPKKK	cd06606	1.2e-16	739	999
STKc_Cdc7_like	cd06627	3.2e-10	739	1001
STKc_YSK4	cd06631	9.2e-06	739	1010
STKc_CCRK	cd07832	1.8e-07	739	999
STKc_Pho85	cd07836	0.00032	739	1010
STKc_CDK5	cd07839	0.0002	739	1010
STKc_CDK7	cd07841	0.00022	739	1014
STKc_CDK2_3	cd07860	0.00025	739	1010
STKc_CDK4	cd07863	3.2e-06	739	1010
STKc_CDK1_euk	cd07861	0.00054	739	1007
STKc_Nek	cd08215	1e-11	739	1007
STKc_Nek1	cd08218	8e-08	739	1010
STKc_Nek3	cd08219	1.2e-08	739	1010
STKc_Nek8	cd08220	2e-05	739	1010
STKc_Nek9	cd08221	2.9e-07	739	1007
STKc_Nek4	cd08223	3.4e-06	739	1010
STKc_Nek5	cd08225	4.4e-07	739	1010
STKc_Nek10	cd08528	2.1e-05	739	1007
STKc_CNK2-like	cd08530	1.2e-06	739	1010
PTKc_Axl_like	cd05035	1.3e-53	740	1009
PTKc_Tyro3	cd05074	3.9e-46	740	1009
PTKc_Axl	cd05075	1.3e-50	740	1009
STKc_CMGC	cd05118	2.1e-08	740	998
STKc_PKN	cd05589	0.00046	740	1014
STKc_CDK_like	cd07829	3.6e-06	740	998
STKc_MAK_like	cd07830	8.7e-08	740	998
STKc_CDK1_like	cd07835	1.4e-06	740	1007
STKc_CDK4_6_like	cd07838	2e-05	740	998
STKc_CDK9_like	cd07840	4.4e-05	740	998
STKc_PDK1	cd05581	3.7e-11	741	1003
STKc_MEKK3_like	cd06625	1.1e-07	742	1010
STKc_MEKK3	cd06651	8.4e-06	742	1009
STKc_RSK_N	cd05582	0.00041	743	1010
STKc_OSR1_SPAK	cd06610	6.3e-06	743	1001
STKc_Nek2	cd08217	2.2e-07	743	1010
PTKc	cd00192	1.4e-122	744	1006
PTK_Jak_rpt1	cd05037	1.2e-10	744	1006
PTKc_Ack_like	cd05040	1.6e-49	744	1007
PTKc_Fes_like	cd05041	1.4e-47	744	1007
PTKc_Aatyk	cd05042	7.3e-32	744	1007
PTKc_Tie	cd05047	5.9e-39	744	1010
PTKc_c-ros	cd05044	1.1e-71	744	1007
PTKc_Met_Ron	cd05058	1e-57	744	1011
PTKc_Syk_like	cd05060	3.5e-56	744	1010
PTK_Jak1_rpt1	cd05077	1e-08	744	1006
PTK_Jak2_Jak3_rpt1	cd05078	6.9e-13	744	1006
PTKc_Fes	cd05084	2.1e-50	744	1007
PTKc_Fer	cd05085	3.2e-48	744	1007
PTKc_Aatyk2	cd05086	1.2e-28	744	1007
PTKc_Aatyk1_Aatyk3	cd05087	2.6e-45	744	1007
PTKc_Zap-70	cd05115	1.9e-42	744	1010
PTKc_Syk	cd05116	1.3e-49	744	1010
STKc_PKC	cd05570	0.00026	744	1001
STKc_MAPKKK_Byr2_lik	cd06628	1.2e-09	744	1010
STKc_MEKK1	cd06630	4.6e-05	744	999
STKc_FA2-like	cd08529	3.1e-08	744	1005
PKc	cd00180	4.2e-51	746	1005
STKc_AGC	cd05123	3e-07	746	1001
STKc_cGK_PKG	cd05572	1e-06	746	1009
STKc_MEKK1_plant	cd06632	1.9e-08	746	1001
STKc_MAPKKK_Bck1_lik	cd06629	1.2e-08	747	999
STKc_MEKK4	cd06626	0.00014	748	1010
STKc_CDC2L1	cd07843	0.00061	750	998
STKc_MAST_like	cd05579	1.7e-05	751	1003
ig	pfam00047	2.1e-06	46	103
ig	pfam00047	3.2e-10	143	202
ig	pfam00047	0.00088	336	393
ig	pfam00047	2.5e-08	517	572
Pkinase	pfam00069	2.2e-27	740	1005
I-set	pfam07679	0.00013	32	121
IG	smart00409	3.7e-05	38	122
IG_like	smart00410	3.7e-05	38	122
IGc2	smart00408	2.2e-07	45	108
I-set	pfam07679	1.2e-11	128	217
IG	smart00409	3.9e-10	135	220
IG_like	smart00410	3.9e-10	135	220
IGc2	smart00408	4.3e-13	142	207
I-set	pfam07679	0.00013	225	319
IG	smart00409	1.8e-07	231	320
IG_like	smart00410	1.8e-07	231	320
IGc2	smart00408	0.00057	238	308
IG	smart00409	8e-06	328	409
IG_like	smart00410	8e-06	328	409
I-set	pfam07679	2.3e-06	331	408
IGc2	smart00408	1.6e-06	335	398
I-set	pfam07679	9.3e-12	412	498
IG	smart00409	1e-13	418	499
IG_like	smart00410	1e-13	418	499
I-set	pfam07679	1.2e-12	502	588
IG	smart00409	6.8e-11	508	589
IG_like	smart00410	6.8e-11	508	589
IGc2	smart00408	1e-10	516	577
Pkinase_Tyr	pfam07714	4.2e-116	740	1005
TyrKc	smart00219	4.4e-120	740	1005
STYKc	smart00221	6.2e-37	740	1007
S_TKc	smart00220	6.6e-33	750	1010

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs34764696	Polymorphism	p.ALA721VAL	N/A
dbSNP	rs34865794	Polymorphism	p.ARG982GLN	N/A
dbSNP	rs34021075	Polymorphism	p.THR410SER	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258