Results for the protein: Q00532

Results for the Protein: Q00532

229463050

8814

CDKL1

NCBI, UniProt

CDKL1_HUMAN RecName: Full=Cyclin-dependent kinase-like 1; AltName: Full=Protein kinase p42 KKIALRE; AltName: Full=Serine/threonine-protein kinase KKIALRE

			0 4 0 0 4

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Swiss-Prot Protein: Q00532

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_Ror	cd05048	1.5e-08	1	239
PTKc_DDR	cd05051	0.00011	1	289
PTKc_Abl	cd05052	3e-08	1	257
PTKc_PDGFR	cd05055	0.0005	1	240
PTKc_EGFR_like	cd05057	0.00017	1	279
PTKc_Tec_like	cd05059	1.5e-08	1	223
PTKc_EphR_B	cd05065	0.00052	1	253
PTKc_Lck_Blk	cd05067	3.4e-05	1	290
PTKc_Frk_like	cd05068	1.2e-07	1	256
PTKc_Yes	cd05069	6.5e-05	1	258
PTKc_Fyn_Yrk	cd05070	0.00019	1	258
PTKc_Src	cd05071	0.00031	1	288
PTKc_Lyn	cd05072	3.2e-05	1	256
PTKc_InsR_like	cd05032	2.3e-06	1	289
PTKc_Jak1_rpt2	cd05079	1.1e-05	1	291
PTKc_Csk	cd05082	2.3e-05	1	290
PTKc_Chk	cd05083	0.00013	1	252
PTKc_Ror2	cd05091	5.3e-05	1	253
PTKc_TrkA	cd05092	0.00016	1	266
PTKc_TrkB	cd05093	0.00073	1	265
PTKc_DDR2	cd05095	9.9e-05	1	288
PTKc_DDR_like	cd05097	0.0001	1	288
PTKc_FGFR1	cd05098	0.00033	1	301
PTKc_Btk_Bmx	cd05113	1.5e-06	1	257
PTKc_Tec_Rlk	cd05114	2.2e-06	1	257
PTKc_Ror1	cd05090	1.5e-05	1	253
STKc_ROCK	cd05596	0.00073	1	344
STKc_ROCK2	cd05621	2.8e-05	1	344
STKc_SLK_like	cd06611	4.8e-13	1	299
STKc_MAP4K3_like	cd06613	1.2e-16	1	286
PKc_MKK7	cd06618	1.7e-11	1	306
STKc_ASK	cd06624	8.9e-11	1	287
PKc_MKK4	cd06616	1.6e-08	1	308
STKc_TAO3	cd06633	4.8e-07	1	284
STKc_myosinIIIA	cd06638	3.8e-08	1	287
STKc_myosinIIIB	cd06639	2.3e-07	1	257
STKc_MAP4K3	cd06645	1.1e-13	1	286
STKc_MAP4K5	cd06646	1.1e-09	1	286
STKc_PAK_I	cd06647	1e-17	1	302
STKc_STK10_LOK	cd06644	5.5e-09	1	301
STKc_PAK1	cd06654	7.1e-10	1	304
STKc_PAK2	cd06655	1.4e-12	1	305
STKc_PAK3	cd06656	1.9e-10	1	306
STKc_PAK5	cd06658	1.9e-06	1	301
STKc_PAK6	cd06659	1.5e-08	1	310
STKc_PCTAIRE_like	cd07844	2.2e-69	1	287
STKc_CDK10	cd07845	9.6e-54	1	306
STKc_MAPK15	cd07852	2.4e-38	1	327
STKc_CDK12	cd07864	1.7e-51	1	287
STKc_CDK9	cd07865	2.8e-46	1	287
STKc_BUR1	cd07866	5.2e-31	1	287
STKc_CDC2L6	cd07867	1.4e-24	1	287
STKc_CDK8	cd07868	2.1e-24	1	287
STKc_PFTAIRE1	cd07869	9.2e-39	1	295
STKc_TEY_MAPK_plant	cd07858	1.9e-60	1	325
STKc_PFTAIRE2	cd07870	4.5e-45	1	287
STKc_JNK	cd07850	4.1e-19	1	320
STKc_PCTAIRE3	cd07871	5.8e-57	1	287
STKc_PCTAIRE1	cd07873	3.3e-51	1	298
STKc_JNK3	cd07874	3.7e-12	1	330
STKc_JNK1	cd07875	8.6e-10	1	332
STKc_JNK2	cd07876	1.9e-11	1	330
STKc_p38gamma_MAPK12	cd07880	3.1e-33	1	327
STKc_PCTAIRE2	cd07872	1.3e-46	1	306
STKc_Nek6_Nek7	cd08224	2.4e-10	1	302
STKc_Nek6	cd08228	7.2e-09	1	270
STKc_Nek7	cd08229	1.4e-10	1	270
PTKc_Src_like	cd05034	1.9e-07	2	290
PTKc_ALK_LTK	cd05036	4.2e-05	2	234
PTKc_Musk	cd05050	2.3e-07	2	284
PTKc_FGFR	cd05053	3.6e-07	2	230
PTKc_FAK	cd05056	1.9e-06	2	295
PTKc_FGFR4	cd05099	9.5e-06	2	306
PTKc_Itk	cd05112	1.9e-08	2	257
PTKc_Srm_Brk	cd05148	2e-06	2	290
STKc_ROCK_NDR_like	cd05573	8.1e-12	2	322
STKc_phototropin_lik	cd05574	6.6e-08	2	301
STKc_PDK1	cd05581	6.2e-18	2	287
STKc_PKA	cd05580	1.8e-12	2	320
STKc_DMPK_like	cd05597	6.1e-07	2	355
STKc_LATS	cd05598	2.3e-05	2	326
STKc_NDR_like	cd05599	2.4e-06	2	318
STKc_Sid2p_Dbf2p	cd05600	1.9e-08	2	321
STKc_CRIK	cd05601	1.9e-08	2	334
STKc_MAST	cd05609	8.4e-09	2	339
STKc_MRCK_alpha	cd05623	8.9e-06	2	293
STKc_MRCK_beta	cd05624	5.3e-05	2	292
STKc_LATS1	cd05625	0.00041	2	326
STKc_NDR1	cd05628	0.00079	2	294
STKc_NDR_like_fungal	cd05629	0.00074	2	355
STKc_PRKX_like	cd05612	2.5e-08	2	321
PKc_MAPKK	cd06605	5.8e-17	2	292
STKc_TAO	cd06607	2e-10	2	318
STKc_myosinIII_like	cd06608	4.8e-13	2	287
STKc_MST3_like	cd06609	4.5e-18	2	304
STKc_OSR1_SPAK	cd06610	1.4e-13	2	287
STKc_MST1_2	cd06612	4.2e-17	2	287
STKc_PAK	cd06614	2.2e-20	2	300
PKc_MEK	cd06615	2.4e-13	2	308
PKc_MKK3_6	cd06617	2.6e-10	2	302
PKc_MKK5	cd06619	4.9e-08	2	312
PKc_MAPKK_Byr1_like	cd06620	1.8e-10	2	297
PKc_MAPKK_Pek1_like	cd06621	6.4e-12	2	298
PKc_MAPKK_PBS2_like	cd06622	2.2e-09	2	341
PKc_MAPKK_plant_like	cd06623	7.7e-22	2	292
STKc_TAO2	cd06634	6e-10	2	319
STKc_TAO1	cd06635	3e-08	2	284
STKc_MST4	cd06640	2.8e-07	2	307
STKc_MST3	cd06641	1.8e-07	2	290
STKc_STK25-YSK1	cd06642	1.4e-07	2	308
STKc_SLK	cd06643	2.6e-10	2	299
STKc_PAK_II	cd06648	9.9e-12	2	300
PKc_MEK2	cd06649	8.1e-09	2	320
PKc_MEK1	cd06650	5.1e-08	2	311
STKc_MEKK3_like_1	cd06653	1.1e-07	2	252
STKc_PAK4	cd06657	3.6e-07	2	303
STKc_NAK1_like	cd06917	4.6e-14	2	301
STKc_CdkB_plant	cd07837	4.7e-71	2	288
STKc_CDC2L1	cd07843	2.9e-58	2	287
STKc_CDKL2_3	cd07846	8.1e-183	2	287
STKc_CDKL1_4	cd07847	1.1e-192	2	287
STKc_CDKL5	cd07848	4.2e-94	2	287
STKc_CDKL	cd07833	1.3e-222	2	287
STKc_ERK1_2_like	cd07849	2.9e-32	2	322
STKc_p38	cd07851	1.4e-25	2	325
STKc_ERK5	cd07855	5.6e-22	2	319
STKc_Sty1_Hog1	cd07856	1.1e-31	2	312
STKc_CDK6	cd07862	3.8e-45	2	287
STKc_p38alpha_MAPK14	cd07877	5.5e-22	2	327
STKc_p38beta_MAPK11	cd07878	1.1e-23	2	325
STKc_p38delta_MAPK13	cd07879	8e-38	2	327
PK_STRAD	cd08216	4.4e-09	2	299
PK_STRAD_beta	cd08226	2.3e-05	2	304
SPS1	COG0515	1.6e-55	2	351
PTKc_EphR	cd05033	6.1e-06	3	236
PTKc_Trk	cd05049	1.3e-06	3	298
PTKc_Hck	cd05073	4.3e-05	3	253
PTKc_FGFR2	cd05101	0.00011	3	301
PKc_STE	cd05122	5.5e-31	3	286
STKc_Yank1	cd05578	1e-13	3	287
STKc_MSK_N	cd05583	1.9e-08	3	307
STKc_cPKC	cd05587	2.9e-06	3	356
STKc_GRK4_like	cd05605	9.5e-08	3	309
STKc_MSK1_N	cd05613	5.6e-07	3	307
STKc_MSK2_N	cd05614	1.3e-07	3	346
STKc_cPKC_alpha	cd05615	3.3e-05	3	351
STKc_cPKC_beta	cd05616	0.00055	3	346
STKc_GRK6	cd05630	6.3e-05	3	272
STKc_GRK4	cd05631	0.00017	3	308
STKc_GRK5	cd05632	6.4e-06	3	305
STKc_MAPKKK	cd06606	9.4e-40	3	287
STKc_MEKK4	cd06626	8.2e-20	3	287
STKc_MAPKKK_Byr2_lik	cd06628	1.6e-18	3	287
STKc_MEKK1	cd06630	3.4e-10	3	288
STKc_YSK4	cd06631	2.5e-11	3	287
STKc_Cdc7_like	cd06627	1.5e-19	3	287
STKc_CCRK	cd07832	1.4e-85	3	288
STKc_MAPK	cd07834	3e-54	3	320
STKc_Pho85	cd07836	3.8e-73	3	287
STKc_CDK5	cd07839	2.2e-82	3	287
STKc_CDK7	cd07841	1.1e-70	3	297
STKc_CDK8_like	cd07842	8.7e-46	3	287
STKc_MAPK4_6	cd07854	4.1e-17	3	320
STKc_MPK1	cd07857	3.4e-31	3	330
STKc_NLK	cd07853	2.3e-18	3	341
STKc_TDY_MAPK_plant	cd07859	1.3e-58	3	327
STKc_CDK2_3	cd07860	2.6e-79	3	287
STKc_CDK1_euk	cd07861	6e-84	3	287
STKc_CDK4	cd07863	1.4e-47	3	287
STKc_Nek2	cd08217	5.7e-19	3	287
STKc_Nek1	cd08218	1.9e-24	3	256
STKc_Nek3	cd08219	9.1e-16	3	254
STKc_Nek8	cd08220	1.4e-12	3	287
STKc_Nek9	cd08221	5.8e-12	3	287
STKc_Nek11	cd08222	1.4e-07	3	254
STKc_Nek4	cd08223	9.6e-13	3	287
STKc_Nek5	cd08225	1.6e-14	3	256
STKc_Nek	cd08215	1.6e-22	3	287
STKc_Nek10	cd08528	6.5e-08	3	258
STKc_FA2-like	cd08529	2.5e-15	3	287
STKc_CNK2-like	cd08530	6.6e-10	3	287
PTKc_Jak_rpt2	cd05038	2.7e-08	4	291
PTKc_Jak2_Jak3_rpt2	cd05081	2.5e-08	4	291
STKc_CMGC	cd05118	6.8e-191	4	287
STKc_PKN	cd05589	5.7e-07	4	353
STKc_MAP4K4_6	cd06636	7.3e-07	4	287
STKc_TNIK	cd06637	1e-08	4	287
STKc_CDK_like	cd07829	8.4e-104	4	287
STKc_MAK_like	cd07830	8.5e-87	4	287
STKc_MOK	cd07831	8.9e-51	4	287
STKc_CDK1_like	cd07835	5.1e-78	4	287
STKc_CDK4_6_like	cd07838	8.8e-40	4	287
STKc_CDK9_like	cd07840	4.4e-68	4	287
PTKc_Tyk2_rpt2	cd05080	2.2e-06	5	292
PK_STRAD_alpha	cd08227	0.00071	5	303
STKc_SGK1	cd05602	2.8e-06	6	355
STKc_MEKK3_like	cd06625	3.3e-14	6	287
STKc_MAPKKK_Bck1_lik	cd06629	5.2e-15	6	287
STKc_MEKK1_plant	cd06632	2.9e-14	6	287
STKc_MEKK3	cd06651	7.8e-10	6	256
STKc_MEKK2	cd06652	8.7e-07	6	255
STKc_RSK_N	cd05582	7e-05	7	345
STKc_p70S6K	cd05584	7.7e-06	7	355
STKc_Rim15_like	cd05611	3.8e-06	7	290
PTKc	cd00192	1.4e-11	8	286
PTKc_Ack_like	cd05040	8.6e-09	8	230
PTKc_Aatyk	cd05042	8e-06	8	284
PTKc_Fes_like	cd05041	2.1e-08	8	234
PTKc_Syk_like	cd05060	2.6e-05	8	227
PTKc_Fes	cd05084	3.1e-07	8	237
PTKc_Aatyk2	cd05086	0.00019	8	253
PTKc_Aatyk1_Aatyk3	cd05087	0.00054	8	258
PTKc_Syk	cd05116	5.6e-07	8	258
STKc_nPKC_theta_delt	cd05592	2.7e-07	8	355
STKc_nPKC_theta	cd05619	1.3e-06	8	357
STKc_SGK2	cd05603	5.9e-08	8	336
PTKc_Zap-70	cd05115	1.5e-05	9	258
PKc	cd00180	5.5e-79	10	285
PTKc_c-ros	cd05044	8.8e-05	10	284
PTKc_Met_Ron	cd05058	0.0006	10	259
PTKc_Fer	cd05085	8.9e-07	10	255
STKc_AGC	cd05123	2.5e-18	10	287
STKc_PKC	cd05570	2.1e-10	10	345
STKc_PKB	cd05571	1e-10	10	355
STKc_cGK_PKG	cd05572	3e-10	10	294
STKc_SGK	cd05575	5.4e-08	10	355
STKc_YPK1_like	cd05585	3.8e-10	10	343
STKc_MAST_like	cd05579	5.9e-17	10	292
STKc_Sck1_like	cd05586	1.6e-07	10	357
STKc_aPKC	cd05588	3.2e-10	10	346
STKc_nPKC_eta	cd05590	2.9e-07	10	354
STKc_nPKC_epsilon	cd05591	1.1e-08	10	346
STKc_PKB_gamma	cd05593	3.7e-07	10	349
STKc_PKB_alpha	cd05594	3.5e-08	10	356
STKc_PKB_beta	cd05595	5.2e-07	10	355
STKc_SGK3	cd05604	2e-05	10	357
STKc_GRK	cd05577	1.3e-09	10	295
STKc_GRK7	cd05607	2.6e-08	10	271
STKc_GRK1	cd05608	3.2e-08	10	307
STKc_beta_ARK	cd05606	4.1e-06	10	273
STKc_aPKC_zeta	cd05617	2.3e-09	10	346
STKc_aPKC_iota	cd05618	1.4e-07	10	356
STKc_GRK3	cd05633	1.2e-05	10	308
Pkinase	pfam00069	8.1e-125	4	287
Pkinase_Tyr	pfam07714	8.6e-16	4	235
STYKc	smart00221	5.3e-96	4	287
TyrKc	smart00219	6.9e-15	4	253
S_TKc	smart00220	4.1e-109	14	287

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_020577	Polymorphism	p.GLN274GLU	N/A
Swiss-Prot	VAR_020576	Polymorphism	p.LEU66PRO	N/A
Swiss-Prot	VAR_020578	Polymorphism	p.LEU329VAL	N/A
Swiss-Prot	VAR_020579	Polymorphism	p.LYS341ASN	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258