Results for the protein: Q9NQU5

Results for the Protein: Q9NQU5

23396789

56924

PAK6

NCBI, UniProt

PAK6_HUMAN RecName: Full=Serine/threonine-protein kinase PAK 6; AltName: Full=PAK-5; AltName: Full=p21-activated kinase 6; Short=PAK-6

			0 13 0 3 10

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Swiss-Prot Protein: Q9NQU5

Identical to: NP_064553, NP_001122100, NP_001122101

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
CRIB_PAK_like	cd01093	1.1e-18	10	55
PTKc_VEGFR3	cd05102	9e-05	325	662
PTKc_VEGFR2	cd05103	2.8e-05	325	662
STKc_ROCK2	cd05621	5.4e-08	360	675
STKc_ROCK1	cd05622	1.2e-06	369	676
STKc_ROCK	cd05596	1.5e-07	371	681
STKc_TAO1	cd06635	2.4e-33	378	677
STKc_TAO3	cd06633	2.4e-34	381	677
PTKc_FGFR1	cd05098	8.8e-05	383	664
STKc_myosinIIIB	cd06639	6.4e-43	384	659
STKc_PAK5	cd06658	6.7e-204	385	675
STKc_PAK6	cd06659	3.3e-259	385	681
STKc_p38delta_MAPK13	cd07879	0.00022	385	680
PTKc_EGFR_like	cd05057	4.7e-05	386	672
STKc_PAK1	cd06654	3.7e-106	386	681
STKc_PAK4	cd06657	4.8e-199	386	677
STKc_JNK1	cd07875	9e-07	386	681
STKc_JNK2	cd07876	1.8e-07	386	680
STKc_PAK	cd06614	5.2e-182	387	671
STKc_PAK_I	cd06647	8.9e-116	387	679
STKc_PAK_II	cd06648	3.7e-243	387	671
STKc_PAK3	cd06656	8.1e-106	387	680
STKc_PAK2	cd06655	7e-106	387	681
STKc_p38alpha_MAPK14	cd07877	1.4e-06	387	680
PTKc_Ror	cd05048	2.5e-06	388	634
PTKc_Ror1	cd05090	2.2e-05	388	655
STKc_p38gamma_MAPK12	cd07880	3.9e-08	389	681
PTKc_PDGFR	cd05055	0.00029	390	635
STKc_p38beta_MAPK11	cd07878	1.4e-06	390	680
PTKc_FGFR2	cd05101	3.6e-05	391	664
STKc_TAO	cd06607	2e-38	391	680
STKc_TAO2	cd06634	4.5e-33	391	678
STKc_myosinIIIA	cd06638	9.6e-43	391	658
PKc_MKK7	cd06618	5.1e-15	393	673
STKc_p38	cd07851	3.6e-10	393	676
PTKc_FGFR4	cd05099	8e-06	394	680
STKc_STK10_LOK	cd06644	2.5e-54	394	678
STKc_JNK	cd07850	3.4e-09	394	681
STKc_MAP4K4_6	cd06636	6e-48	395	658
PTK_Ryk	cd05043	2.7e-05	396	638
PTKc_Csk	cd05082	5.6e-07	396	656
STKc_JNK3	cd07874	5.7e-07	396	680
STKc_BUR1	cd07866	4.9e-12	397	658
PTKc_Btk_Bmx	cd05113	2.2e-10	398	657
PKc_MAPKK_Byr1_like	cd06620	1.2e-12	398	664
STKc_ASK	cd06624	7.1e-36	398	658
STKc_MAP4K3	cd06645	2.3e-62	398	657
STKc_MAP4K5	cd06646	2.1e-60	398	657
STKc_ERK5	cd07855	4.2e-10	399	677
STKc_CDK9	cd07865	2.7e-10	399	658
PTKc_FGFR	cd05053	3.7e-06	400	658
PTKc_EphR_A2	cd05063	9.9e-06	400	663
PTKc_FAK	cd05056	1.6e-08	400	666
STKc_TNIK	cd06637	6.7e-47	400	658
PTKc_Jak_rpt2	cd05038	2.7e-09	401	660
PTKc_FGFR3	cd05100	0.00055	401	681
STKc_Sid2p_Dbf2p	cd05600	2.6e-07	401	676
STKc_SLK_like	cd06611	2.8e-55	401	673
STKc_SLK	cd06643	2.7e-49	401	676
STKc_CDK10	cd07845	3.4e-13	401	664
STKc_Sty1_Hog1	cd07856	4.3e-10	401	674
PTKc_EphR	cd05033	7.1e-08	402	639
PTKc_Tec_like	cd05059	1.8e-10	402	657
PTKc_Jak2_Jak3_rpt2	cd05081	2.1e-07	402	660
PTKc_Itk	cd05112	2.4e-09	402	657
PTKc_Tec_Rlk	cd05114	1.1e-10	402	657
STKc_MSK_N	cd05583	2.4e-11	402	669
STKc_MST4	cd06640	4.8e-55	402	678
STKc_MST3	cd06641	1.1e-54	402	678
STKc_STK25-YSK1	cd06642	8.9e-58	402	678
PTKc_Src_like	cd05034	1e-07	403	656
PTKc_Csk_like	cd05039	7.1e-06	403	616
PTK_CCK4	cd05046	2.7e-05	403	654
PTKc_Trk	cd05049	3.6e-08	403	661
PTKc_Musk	cd05050	2.7e-09	403	655
PTKc_DDR	cd05051	0.001	403	660
PTKc_Abl	cd05052	9.8e-07	403	657
PTKc_InsR	cd05061	6e-08	403	663
PTKc_IGF-1R	cd05062	5.3e-07	403	658
PTKc_ALK_LTK	cd05036	2.5e-09	403	640
PTKc_Frk_like	cd05068	2.2e-11	403	655
PTKc_Yes	cd05069	5.4e-07	403	656
PTKc_Fyn_Yrk	cd05070	9.7e-06	403	661
PTKc_Lck_Blk	cd05067	3.1e-06	403	681
PTKc_Src	cd05071	9.6e-06	403	658
PTKc_Hck	cd05073	2.6e-08	403	656
PTKc_Lyn	cd05072	4.2e-07	403	656
PTKc_DDR2	cd05095	1.6e-05	403	660
PTKc_DDR_like	cd05097	6.2e-05	403	660
PTK_HER3	cd05111	5.6e-06	403	670
PTKc_Srm_Brk	cd05148	2e-07	403	656
STKc_MST1_2	cd06612	1.5e-73	403	658
STKc_MAP4K3_like	cd06613	2.9e-87	403	657
STKc_MEKK3_like_1	cd06653	4.9e-18	403	658
STKc_TEY_MAPK_plant	cd07858	2.2e-07	403	680
PTKc_InsR_like	cd05032	1.5e-08	404	661
PTKc_RET	cd05045	5.8e-05	404	642
PTKc_Jak1_rpt2	cd05079	4.5e-05	404	678
PTKc_TrkA	cd05092	3.6e-06	404	661
PTKc_TrkB	cd05093	3e-05	404	668
PTKc_HER2	cd05109	0.00023	404	650
STKc_Cdc7_like	cd06627	4.5e-62	404	658
PKc_MEK2	cd06649	2.2e-09	404	680
STKc_MEKK3	cd06651	1.4e-20	404	660
PKc_MEK1	cd06650	8e-08	404	680
STKc_MAPK	cd07834	2e-12	404	681
STKc_TDY_MAPK_plant	cd07859	5.8e-08	404	680
STKc_CDK12	cd07864	1.3e-12	404	658
STKc_Nek11	cd08222	1.1e-18	404	658
PTKc_c-ros	cd05044	4.3e-06	405	655
PTKc_Chk	cd05083	1.8e-06	405	655
PTKc_Tie2	cd05088	4.5e-06	405	681
PTKc_Tyro3	cd05074	3.7e-06	405	660
PKc_STE	cd05122	1.4e-123	405	657
STKc_MST3_like	cd06609	4.2e-71	405	678
PKc_MAPKK_plant_like	cd06623	3.3e-40	405	664
PKc_MKK5	cd06619	2.4e-18	405	681
STKc_CDC2L6	cd07867	6.3e-06	405	658
STKc_CDK8	cd07868	1.1e-05	405	658
PTKc_EphR_A10	cd05064	1.9e-07	406	662
PTKc_EphR_A	cd05066	8.4e-06	406	660
STKc_GRK4_like	cd05605	9.5e-11	406	671
STKc_GRK6	cd05630	3.3e-08	406	679
STKc_GRK4	cd05631	2.5e-07	406	669
STKc_GRK5	cd05632	1.2e-08	406	671
STKc_myosinIII_like	cd06608	2.1e-55	406	658
STKc_PCTAIRE_like	cd07844	2.7e-10	406	658
STKc_NLK	cd07853	1.1e-07	406	680
STKc_MAPK4_6	cd07854	2.5e-07	406	679
STKc_CDK2_3	cd07860	1.5e-21	406	658
STKc_CDK4	cd07863	1.7e-11	406	658
STKc_Nek5	cd08225	3.4e-27	406	658
STKc_Nek6	cd08228	1.1e-13	406	661
PTKc_Axl_like	cd05035	1.1e-05	407	660
PTKc_EphR_B	cd05065	3.5e-07	407	660
PTKc_Axl	cd05075	0.00037	407	662
PTKc_Tyk2_rpt2	cd05080	9.7e-07	407	676
PTKc_Tie1	cd05089	0.00015	407	680
STKc_PKA	cd05580	9.9e-17	407	674
STKc_cPKC	cd05587	2.6e-07	407	681
STKc_PKN	cd05589	2.6e-08	407	680
STKc_DMPK_like	cd05597	6e-07	407	681
STKc_CRIK	cd05601	1.3e-08	407	681
STKc_MAST	cd05609	2.7e-10	407	681
STKc_PRKX_like	cd05612	2.4e-14	407	675
STKc_MSK1_N	cd05613	1.4e-09	407	677
STKc_cPKC_alpha	cd05615	4.7e-07	407	672
STKc_cPKC_beta	cd05616	7.6e-07	407	676
STKc_MRCK_alpha	cd05623	5.9e-06	407	681
STKc_MRCK_beta	cd05624	2.3e-06	407	676
STKc_NDR2	cd05627	1.6e-05	407	678
STKc_NDR1	cd05628	5.9e-08	407	678
PKc_MAPKK	cd06605	3.6e-20	407	663
PKc_MEK	cd06615	8e-15	407	671
PKc_MKK4	cd06616	1.9e-13	407	672
PKc_MAPKK_PBS2_like	cd06622	2.2e-11	407	676
STKc_CDK1_like	cd07835	1.5e-15	407	658
STKc_CDKL1_4	cd07847	5.7e-22	407	658
STKc_CDKL5	cd07848	7.6e-06	407	658
STKc_MAPK15	cd07852	3.1e-12	407	677
STKc_CDK6	cd07862	2.1e-07	407	658
STKc_PCTAIRE3	cd07871	5e-07	407	658
STKc_PCTAIRE2	cd07872	6.5e-07	407	674
STKc_PCTAIRE1	cd07873	1.9e-06	407	665
STKc_Nek3	cd08219	2.9e-19	407	658
STKc_Nek6_Nek7	cd08224	4.6e-14	407	661
STKc_Nek7	cd08229	9.9e-14	407	661
PTKc_TrkC	cd05094	0.00028	408	668
STKc_ROCK_NDR_like	cd05573	5.8e-15	408	675
STKc_phototropin_lik	cd05574	3.5e-12	408	671
STKc_PDK1	cd05581	9.1e-22	408	658
STKc_LATS	cd05598	3.8e-08	408	680
STKc_LATS1	cd05625	1.8e-06	408	679
STKc_NDR_like_fungal	cd05629	0.00064	408	681
STKc_LATS2	cd05626	2.5e-05	408	678
STKc_OSR1_SPAK	cd06610	9.8e-63	408	658
PKc_MAPKK_Pek1_like	cd06621	5.1e-18	408	667
PKc_MKK3_6	cd06617	9.5e-16	408	673
STKc_NAK1_like	cd06917	2.6e-41	408	675
STKc_CdkB_plant	cd07837	6.6e-13	408	659
STKc_CDK5	cd07839	5.4e-11	408	658
STKc_CDC2L1	cd07843	2e-10	408	658
STKc_CDKL2_3	cd07846	3.6e-13	408	658
STKc_ERK1_2_like	cd07849	2.5e-09	408	679
STKc_PFTAIRE1	cd07869	2.5e-05	408	672
STKc_PFTAIRE2	cd07870	2.1e-09	408	658
PK_STRAD	cd08216	5.6e-15	408	673
PK_STRAD_beta	cd08226	5.2e-07	408	676
PK_STRAD_alpha	cd08227	4.3e-09	408	669
STKc_Nek10	cd08528	6.9e-10	408	654
SPS1	COG0515	1e-38	408	681
STKc_MSK2_N	cd05614	2.5e-07	409	679
STKc_MAPKKK	cd06606	1.3e-72	409	658
STKc_MAPKKK_Byr2_lik	cd06628	4.1e-42	409	658
STKc_MAPKKK_Bck1_lik	cd06629	1.1e-21	409	658
STKc_MEKK1	cd06630	2.1e-12	409	659
STKc_Pho85	cd07836	4e-15	409	658
STKc_CDK7	cd07841	3.6e-14	409	672
STKc_CDK8_like	cd07842	1.2e-09	409	658
STKc_CDK1_euk	cd07861	1.7e-18	409	658
STKc_Nek	cd08215	9.6e-33	409	658
STKc_Nek1	cd08218	2.8e-31	409	658
STKc_Nek8	cd08220	6.2e-16	409	658
STKc_Nek9	cd08221	5.5e-18	409	658
STKc_Nek4	cd08223	9.3e-24	409	658
STKc_RSK_N	cd05582	4.6e-07	410	681
STKc_p70S6K	cd05584	4.3e-08	410	680
STKc_CDK_like	cd07829	2.7e-20	410	658
STKc_MAK_like	cd07830	7.2e-16	410	658
STKc_CDK4_6_like	cd07838	9e-13	410	658
STKc_CDK9_like	cd07840	2.9e-14	410	658
PTKc	cd00192	1.1e-16	411	657
PTKc_Ack_like	cd05040	3.9e-10	411	660
PTKc_Fes_like	cd05041	1.3e-10	411	655
PTKc_Syk_like	cd05060	1.4e-07	411	644
PTKc_Aatyk1_Aatyk3	cd05087	0.00093	411	660
PTKc_Zap-70	cd05115	4.8e-06	411	661
PTKc_Syk	cd05116	5.4e-06	411	658
STKc_PKC	cd05570	1.1e-12	411	681
STKc_SGK	cd05575	3.2e-08	411	681
STKc_nPKC_theta_delt	cd05592	7.2e-09	411	680
STKc_SGK2	cd05603	3.8e-09	411	681
STKc_nPKC_theta	cd05619	3.5e-09	411	681
STKc_MEKK4	cd06626	1.2e-22	411	658
STKc_FA2-like	cd08529	5.1e-15	411	658
PTK_Jak1_rpt1	cd05077	0.00045	412	657
PTK_Jak2_Jak3_rpt1	cd05078	5.8e-06	412	644
PTKc_Fes	cd05084	2.5e-08	412	654
STKc_CMGC	cd05118	7.2e-17	412	658
STKc_MOK	cd07831	9.5e-11	412	658
STKc_CCRK	cd07832	1.2e-14	412	659
STKc_CDKL	cd07833	3.1e-13	412	658
STKc_MPK1	cd07857	7.1e-09	412	681
STKc_Nek2	cd08217	2.8e-17	412	658
STKc_CNK2-like	cd08530	2.1e-13	412	658
PKc	cd00180	1e-77	413	656
PTKc_Aatyk	cd05042	4.1e-05	413	655
PTKc_Tie	cd05047	1e-05	413	660
PTKc_Met_Ron	cd05058	1.8e-05	413	662
PTKc_Fer	cd05085	3.9e-07	413	654
STKc_AGC	cd05123	9.1e-34	413	658
STKc_PKB	cd05571	2.2e-10	413	681
STKc_cGK_PKG	cd05572	2.2e-15	413	665
STKc_GRK	cd05577	2.4e-12	413	670
STKc_Yank1	cd05578	1.3e-18	413	658
STKc_MAST_like	cd05579	1.4e-19	413	661
STKc_YPK1_like	cd05585	6e-09	413	680
STKc_Sck1_like	cd05586	0.00022	413	681
STKc_aPKC	cd05588	1.4e-07	413	681
STKc_nPKC_eta	cd05590	2.2e-08	413	681
STKc_nPKC_epsilon	cd05591	1.4e-08	413	681
STKc_PKB_gamma	cd05593	6.4e-08	413	681
STKc_PKB_alpha	cd05594	2.5e-09	413	680
STKc_PKB_beta	cd05595	2.3e-07	413	679
STKc_NDR_like	cd05599	1.3e-09	413	679
STKc_SGK1	cd05602	3e-07	413	681
STKc_SGK3	cd05604	2.4e-06	413	681
STKc_beta_ARK	cd05606	1.7e-09	413	670
STKc_GRK7	cd05607	5e-08	413	678
STKc_GRK1	cd05608	5.2e-11	413	670
STKc_Rim15_like	cd05611	9e-08	413	657
STKc_aPKC_zeta	cd05617	6.1e-07	413	676
STKc_nPKC_delta	cd05620	3.3e-05	413	681
STKc_aPKC_iota	cd05618	1e-05	413	676
STKc_GRK3	cd05633	3e-08	413	674
STKc_MEKK3_like	cd06625	2.7e-28	413	658
STKc_YSK4	cd06631	6.7e-21	413	658
STKc_MEKK1_plant	cd06632	5.2e-38	413	658
STKc_MEKK2	cd06652	2.1e-14	413	659
PBD	pfam00786	4e-18	11	67
Pkinase	pfam00069	3.7e-80	407	658
PBD	smart00285	2.5e-12	12	47
Pkinase_Tyr	pfam07714	5.2e-19	407	658
TyrKc	smart00219	2.5e-22	407	658
STYKc	smart00221	4.9e-80	407	658
S_TKc	smart00220	1.5e-89	417	658
KIND	smart00750	5.3e-55	487	666

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040976	Polymorphism	p.ALA376VAL	N/A
Swiss-Prot	VAR_051655	Polymorphism	p.ARG103CYS	N/A
Swiss-Prot	VAR_035631	Polymorphism	p.ARG3HIS	N/A
Swiss-Prot	VAR_040972	Polymorphism	p.GLU184LYS	N/A
Swiss-Prot	VAR_051657	Polymorphism	p.GLU475LYS	N/A
Swiss-Prot	VAR_040973	Polymorphism	p.GLY205GLU	N/A
dbSNP	rs3743135	Polymorphism	p.HIS215ARG	N/A
Swiss-Prot	VAR_040977	Polymorphism	p.LEU514ARG	N/A
dbSNP	rs2412504	Polymorphism	p.MET76VAL	N/A
dbSNP	rs3743137	Polymorphism	p.PRO337LEU	N/A
Swiss-Prot	VAR_040974	Polymorphism	p.PRO208THR	N/A
Swiss-Prot	VAR_051656	Polymorphism	p.THR151ILE	N/A
Swiss-Prot	VAR_040975	Polymorphism	p.THR210MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258