Results for the protein: NP

Results for the Protein: NP_009229

237681123

672

BRCA1

NCBI

breast cancer type 1 susceptibility protein isoform 4 [Homo sapiens]

Known Diseases associated with this Protein:
BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1

14

4

14

4

0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: RING - cd00162 RING - smart00184 zf-C3HC4 - pfam00097 BRCT - pfam00533 BRCT - smart00292 BRCT - cd00027	RefSeq Protein: NP_009229 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
BRCT	cd00027	6.4e-12	545	620
BRCT	cd00027	5.3e-11	659	739
zf-C3HC4	pfam00097	1.2e-11	24	64
BRCT	pfam00533	6e-11	538	619
BRCT	pfam00533	4e-12	652	738
RING	smart00184	4.6e-12	24	64
BRCT	smart00292	7e-07	541	622
BRCT	smart00292	9.2e-15	655	741

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs4986849	Polymorphism	p.ARG340GLN	N/A
dbSNP	rs201196020	Polymorphism	p.HIS756PRO	N/A
dbSNP	rs1800062	Polymorphism	p.LYS38ASN	N/A
dbSNP	rs1799966	Polymorphism	p.SER509CYS	N/A
OMIM	113705.0037	Disease	p.ARG544GLU	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0017	Disease	p.ARG340GLY	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0034	Disease	p.ARG71GLY	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0012	Disease	p.ARG1TER	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0016	Disease	p.ARG340TER	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0022	Disease	p.ARG1TRP	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0002	Disease	p.CYS61GLY	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0001	Disease	p.CYS64GLY	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0013	Disease	p.GLU1TER	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0035	Disease	p.MET650ARG	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0036	Disease	p.MET650LYS	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0011	Disease	p.SER1ASN	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0007 113705.0009	Disease	p.SER1TER	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1
OMIM	113705.0019	Disease	p.TYR728TER	BREAST-OVARIAN CANCER, FAMILIAL, SUSCEPTIBILITY TO, 1

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