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Results for the Protein: P41743
239938658

KPCI_HUMAN RecName: Full=Protein kinase C iota type; AltName: Full=Atypical protein kinase C-lambda/iota; Short=PRKC-lambda/iota; Short=aPKC-lambda/iota; AltName: Full=nPKC-iota
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Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

PB1 - smart00666
PB1 - pfam00564
PB1 - cd05992
PB1_aPKC - cd06404
C1_1 - pfam00130
C1 - smart00109
C1 - cd00029
STKc_ROCK2 - cd05621
STKc_ROCK - cd05596
STKc_ROCK1 - cd05622
STKc_TAO1 - cd06635
STKc_myosinIIIB - cd06639
STKc_PAK_II - cd06648
STKc_PAK1 - cd06654
STKc_PAK2 - cd06655
STKc_PAK3 - cd06656
STKc_PAK_I - cd06647
STKc_JNK3 - cd07874
STKc_p38alpha_MAPK14 - cd07877
STKc_JNK1 - cd07875
STKc_p38gamma_MAPK12 - cd07880
STKc_p38 - cd07851
STKc_JNK - cd07850
STKc_p38beta_MAPK11 - cd07878
STKc_TAO - cd06607
STKc_PAK - cd06614
STKc_PAK5 - cd06658
PTKc_EGFR_like - cd05057
STKc_myosinIIIA - cd06638
STKc_PAK4 - cd06657
STKc_PAK6 - cd06659
STKc_MAP4K4_6 - cd06636
STKc_CDK9 - cd07865
STKc_TAO2 - cd06634
STKc_PFTAIRE2 - cd07870
STKc_PFTAIRE1 - cd07869
PKc_MKK7 - cd06618
STKc_MAP4K5 - cd06646
PTKc_FGFR4 - cd05099
STKc_STK10_LOK - cd06644
STKc_MAP4K3 - cd06645
STKc_ASK - cd06624
PTK_HER3 - cd05111
STKc_CDK10 - cd07845
STKc_BUR1 - cd07866
STKc_MAPK4_6 - cd07854
STKc_CDK12 - cd07864
PTKc_FAK - cd05056
PTKc_ALK_LTK - cd05036
PTKc_Tie2 - cd05088
STKc_ERK5 - cd07855
PKc_MEK1 - cd06650
STKc_TEY_MAPK_plant - cd07858
PKc_MEK2 - cd06649
STKc_PCTAIRE2 - cd07872
STKc_PCTAIRE1 - cd07873
PTKc_Csk - cd05082
PTKc_EphR_A10 - cd05064
PTKc_Abl - cd05052
PTKc_Trk - cd05049
PTKc_Frk_like - cd05068
PTKc_InsR - cd05061
PTKc_Yes - cd05069
PTKc_Lyn - cd05072
PTKc_Hck - cd05073
PTKc_Fyn_Yrk - cd05070
PTKc_Itk - cd05112
PTKc_Tec_Rlk - cd05114
PKc_MKK4 - cd06616
PKc_MAPKK_Byr1_like - cd06620
STKc_SLK - cd06643
PTKc_Btk_Bmx - cd05113
PTKc_EGFR - cd05108
PTKc_EphR - cd05033
PTKc_Csk_like - cd05039
PTKc_Tec_like - cd05059
PTKc_InsR_like - cd05032
PTKc_EphR_B - cd05065
PTKc_Chk - cd05083
PTKc_Jak1_rpt2 - cd05079
PTKc_EphR_A - cd05066
PTKc_FGFR - cd05053
STKc_MAP4K3_like - cd06613
STKc_MST1_2 - cd06612
STKc_PCTAIRE_like - cd07844
STKc_Nek7 - cd08229
STKc_Nek6 - cd08228
STKc_MAPK15 - cd07852
STKc_Nek6_Nek7 - cd08224
PTKc_Tie1 - cd05089
STKc_myosinIII_like - cd06608
STKc_TNIK - cd06637
STKc_PCTAIRE3 - cd07871
STKc_MEKK3_like_1 - cd06653
STKc_MEKK2 - cd06652
STKc_STK25-YSK1 - cd06642
PKc_MAPKK_plant_like - cd06623
PKc_MKK5 - cd06619
PKc_MAPKK_PBS2_like - cd06622
PKc_MEK - cd06615
STKc_MEKK3_like - cd06625
PKc_MAPKK_Pek1_like - cd06621
STKc_CDC2L1 - cd07843
STKc_CDK6 - cd07862
SPS1 - COG0515
PKc_MKK3_6 - cd06617
STKc_ERK1_2_like - cd07849
STKc_CDKL5 - cd07848
STKc_CDKL - cd07833
STKc_CdkB_plant - cd07837
STKc_CDKL1_4 - cd07847
STKc_NAK1_like - cd06917
STKc_CDKL2_3 - cd07846
STKc_PDK1 - cd05581
STKc_DMPK_like - cd05597
STKc_NDR_like - cd05599
STKc_Sid2p_Dbf2p - cd05600
STKc_PKA - cd05580
STKc_phototropin_lik - cd05574
PTKc_Src_like - cd05034
PTKc_Jak_rpt2 - cd05038
PTKc_Srm_Brk - cd05148
STKc_ROCK_NDR_like - cd05573
STKc_CRIK - cd05601
STKc_OSR1_SPAK - cd06610
STKc_NDR1 - cd05628
PKc_MAPKK - cd06605
STKc_MST3_like - cd06609
STKc_LATS - cd05598
STKc_NDR2 - cd05627
STKc_NDR_like_fungal - cd05629
STKc_LATS2 - cd05626
STKc_MAST - cd05609
STKc_PRKX_like - cd05612
STKc_MRCK_alpha - cd05623
STKc_MRCK_beta - cd05624
STKc_Nek - cd08215
STKc_Nek1 - cd08218
STKc_MPK1 - cd07857
STKc_Nek2 - cd08217
STKc_CDK1_euk - cd07861
STKc_CDK2_3 - cd07860
STKc_Nek3 - cd08219
STKc_CDK4 - cd07863
STKc_FA2-like - cd08529
STKc_Nek10 - cd08528
STKc_CNK2-like - cd08530
STKc_TDY_MAPK_plant - cd07859
STKc_Nek5 - cd08225
STKc_Nek4 - cd08223
STKc_Nek9 - cd08221
STKc_Nek11 - cd08222
STKc_Nek8 - cd08220
STKc_MAPK - cd07834
STKc_MSK2_N - cd05614
STKc_NLK - cd07853
STKc_cPKC_alpha - cd05615
STKc_GRK4 - cd05631
STKc_MSK1_N - cd05613
STKc_GRK4_like - cd05605
PKc_STE - cd05122
STKc_Yank1 - cd05578
STKc_MSK_N - cd05583
STKc_cPKC - cd05587
STKc_GRK5 - cd05632
STKc_cPKC_beta - cd05616
STKc_CDK5 - cd07839
STKc_CDK7 - cd07841
STKc_CDK8_like - cd07842
STKc_CCRK - cd07832
STKc_GRK6 - cd05630
STKc_Pho85 - cd07836
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_MEKK3 - cd06651
STKc_CDK9_like - cd07840
STKc_CDK4_6_like - cd07838
Pkinase_Tyr - pfam07714
STKc_Sty1_Hog1 - cd07856
STYKc - smart00221
Pkinase - pfam00069
TyrKc - smart00219
STKc_CDK1_like - cd07835
STKc_MAK_like - cd07830
PTKc_Jak2_Jak3_rpt2 - cd05081
PTKc_Tyk2_rpt2 - cd05080
PTKc_Tyro3 - cd05074
STKc_PKN - cd05589
STKc_LATS1 - cd05625
STKc_MOK - cd07831
STKc_MAPKKK_Bck1_lik - cd06629
PTKc_Axl_like - cd05035
STKc_CMGC - cd05118
STKc_MST4 - cd06640
STKc_MST3 - cd06641
STKc_CDK_like - cd07829
PK_STRAD_alpha - cd08227
PK_STRAD - cd08216
STKc_MEKK4 - cd06626
STKc_Rim15_like - cd05611
STKc_p70S6K - cd05584
STKc_RSK_N - cd05582
STKc_PKB_alpha - cd05594
STKc_aPKC_zeta - cd05617
STKc_SGK2 - cd05603
STKc_aPKC_iota - cd05618
STKc_SGK1 - cd05602
STKc_YSK4 - cd06631
STKc_MEKK1_plant - cd06632
STKc_PKB_beta - cd05595
STKc_MEKK1 - cd06630
STKc_MAPKKK_Byr2_lik - cd06628
STKc_nPKC_delta - cd05620
STKc_nPKC_theta - cd05619
STKc_SGK3 - cd05604
PTKc_c-ros - cd05044
PTKc_Fes_like - cd05041
PTKc_Ack_like - cd05040
PTKc - cd00192
STKc_PKB_gamma - cd05593
PTKc_Tie - cd05047
PTK_Jak2_Jak3_rpt1 - cd05078
PTK_Jak1_rpt1 - cd05077
PTKc_Met_Ron - cd05058
PTKc_Fer - cd05085
PTKc_Fes - cd05084
STKc_aPKC - cd05588
STKc_nPKC_eta - cd05590
STKc_nPKC_epsilon - cd05591
STKc_nPKC_theta_delt - cd05592
STKc_SGK - cd05575
STKc_PKB - cd05571
PTKc_Syk - cd05116
PTKc_Aatyk1_Aatyk3 - cd05087
STKc_PKC - cd05570
STKc_beta_ARK - cd05606
STKc_GRK3 - cd05633
STKc_SLK_like - cd06611
STKc_MAST_like - cd05579
STKc_cGK_PKG - cd05572
STKc_AGC - cd05123
PTKc_Zap-70 - cd05115
PTKc_Aatyk - cd05042
PKc - cd00180
STKc_GRK1 - cd05608
STKc_GRK - cd05577
STKc_Sck1_like - cd05586
STKc_GRK7 - cd05607
STKc_YPK1_like - cd05585
S_TKc - smart00220
PTK_Ryk - cd05043
S_TK_X - smart00133
Pkinase_C - pfam00433


Swiss-Prot Protein: P41743
Identical to: NP_002731
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
PB1cd059921.8e-2626106
PB1_aPKCcd064041.6e-6726108
C1cd000291.6e-17141190
STKc_ROCKcd055961.6e-39206586
STKc_ROCK2cd056219e-37206586
STKc_ROCK1cd056227.3e-34206587
STKc_TAO1cd066351.4e-05225540
STKc_myosinIIIBcd066397.7e-08227523
STKc_PAK_IIcd066489.3e-12231530
STKc_PAK1cd066544.8e-07232546
STKc_PAK2cd066557.4e-08233547
STKc_PAK3cd066561.1e-07233548
STKc_PAK_Icd066471.1e-07234544
STKc_JNK3cd078740.00074235591
STKc_p38alpha_MAPK14cd078772.9e-05235565
STKc_JNK1cd078750.00074236591
STKc_JNKcd078505e-05237585
STKc_p38cd078516e-06237541
STKc_p38gamma_MAPK12cd078807e-06237565
STKc_p38beta_MAPK11cd078780.00011237565
STKc_TAOcd066071.1e-05238563
STKc_PAKcd066142.9e-18238536
PTKc_EGFR_likecd050570.00014239508
STKc_myosinIIIAcd066386.3e-08239522
STKc_PAK4cd066579.6e-07239536
STKc_PAK5cd066582.4e-07239534
STKc_PAK6cd066593.2e-09239545
STKc_MAP4K4_6cd066367.6e-07241511
STKc_CDK9cd078654.3e-07241522
PKc_MKK7cd066185.9e-09243545
STKc_TAO2cd066345.3e-06243541
STKc_PFTAIRE1cd078692.4e-06243534
STKc_PFTAIRE2cd078701.4e-08243522
PTKc_FGFR4cd050990.001244542
STKc_STK10_LOKcd066442.9e-09244543
STKc_MAP4K3cd066452.8e-09244510
STKc_MAP4K5cd066463.7e-08244510
STKc_ASKcd066244.2e-17245522
PTK_HER3cd051112.7e-05246508
STKc_CDK10cd078451e-09246541
PTKc_ALK_LTKcd050368.3e-06247522
PTKc_FAKcd050563.1e-06247521
PTKc_Tie2cd050881.4e-05247518
STKc_MAPK4_6cd078543.5e-05247560
STKc_CDK12cd078644.4e-09247522
STKc_BUR1cd078661.5e-06247522
PTKc_Trkcd050490.0007248519
PTKc_Ablcd050521.1e-06248526
PTKc_InsRcd050610.00088248527
PTKc_EphR_A10cd050640.00031248497
PTKc_Frk_likecd050682.8e-06248516
PTKc_Yescd050690.0009248517
PTKc_Fyn_Yrkcd050700.00016248517
PTKc_Lyncd050720.00037248516
PTKc_Hckcd050737.9e-05248496
PTKc_Cskcd050823.7e-06248516
PKc_MEK2cd066491e-06248596
PKc_MEK1cd066505.2e-06248593
STKc_ERK5cd078555.1e-05248546
STKc_TEY_MAPK_plantcd078587.1e-08248565
STKc_PCTAIRE1cd078737.7e-07248534
STKc_PCTAIRE2cd078724.8e-08248542
PTKc_InsR_likecd050320.00045249516
PTKc_EphRcd050330.0001249497
PTKc_Csk_likecd050391.7e-05249488
PTKc_FGFRcd050530.00017249486
PTKc_Tec_likecd050597.1e-08249506
PTKc_EphR_Bcd050650.00024249497
PTKc_EphR_Acd050660.00073249497
PTKc_Jak1_rpt2cd050790.00021249517
PTKc_Chkcd050830.00014249517
PTKc_EGFRcd051080.00049249587
PTKc_Btk_Bmxcd051131.4e-09249517
PTKc_Tec_Rlkcd051143.9e-07249515
PTKc_Itkcd051125.4e-07249511
PKc_MKK4cd066162.7e-08249536
PKc_MAPKK_Byr1_likecd066204.3e-09249533
STKc_SLKcd066431.6e-09249534
STKc_MST1_2cd066121.3e-15250511
STKc_MAP4K3_likecd066135.3e-16250521
STKc_PCTAIRE_likecd078447.2e-15250547
PTKc_Tie1cd050890.00068251517
STKc_myosinIII_likecd066089e-14251522
STKc_TNIKcd066379.8e-09251522
STKc_MAPK15cd078521.3e-07251560
STKc_PCTAIRE3cd078718.5e-09251522
STKc_Nek6_Nek7cd082243.9e-10251518
STKc_Nek6cd082281.9e-08251519
STKc_Nek7cd082291e-10251519
PTKc_Src_likecd050346.1e-05252516
PTKc_Jak_rpt2cd050381.2e-06252526
PTKc_Srm_Brkcd051486.8e-06252514
STKc_ROCK_NDR_likecd055731.1e-66252585
STKc_phototropin_likcd055742e-58252548
STKc_PKAcd055801.5e-101252555
STKc_PDK1cd055811.1e-74252522
STKc_DMPK_likecd055975.7e-59252585
STKc_NDR_likecd055994e-22252588
STKc_Sid2p_Dbf2pcd056003.1e-22252586
STKc_CRIKcd056011.8e-42252585
STKc_LATScd055983.6e-36252590
STKc_MASTcd056093.7e-59252553
STKc_PRKX_likecd056123.2e-81252556
STKc_MRCK_alphacd056233.5e-38252586
STKc_MRCK_betacd056242.9e-42252585
STKc_LATS2cd056264.3e-28252590
STKc_NDR2cd056274.3e-28252593
STKc_NDR1cd056281.2e-25252593
STKc_NDR_like_fungalcd056296.5e-34252593
PKc_MAPKKcd066056.2e-14252527
STKc_MST3_likecd066093.9e-15252540
STKc_OSR1_SPAKcd066102.6e-13252522
PKc_MKK3_6cd066171.3e-09252541
PKc_MKK5cd066192.9e-06252534
PKc_MAPKK_PBS2_likecd066229.1e-09252592
PKc_MAPKK_plant_likecd066232e-19252527
STKc_MEKK3_likecd066252.7e-13252516
PKc_MAPKK_Pek1_likecd066212.9e-09252536
STKc_STK25-YSK1cd066423.7e-09252537
STKc_MEKK2cd066521.2e-06252499
STKc_MEKK3_like_1cd066532.5e-08252497
PKc_MEKcd066152.8e-11252540
STKc_NAK1_likecd069177.3e-14252534
STKc_CDKLcd078331.2e-11252522
STKc_CdkB_plantcd078375.3e-11252523
STKc_CDC2L1cd078431.2e-07252522
STKc_CDKL2_3cd078468.2e-10252522
STKc_CDKL1_4cd078476.3e-15252522
STKc_CDKL5cd078481.3e-06252522
STKc_ERK1_2_likecd078495.5e-06252549
STKc_CDK6cd078628.2e-06252522
SPS1COG05152.6e-54252593
PKc_STEcd051221.6e-24253510
STKc_Yank1cd055782e-75253522
STKc_MSK_Ncd055834.6e-104253541
STKc_cPKCcd055872e-150253586
STKc_GRK4_likecd056051.5e-60253543
STKc_MSK1_Ncd056131e-84253541
STKc_MSK2_Ncd056141.8e-97253587
STKc_cPKC_betacd056168.8e-143253586
STKc_cPKC_alphacd056158.1e-140253586
STKc_GRK4cd056312.4e-50253543
STKc_GRK5cd056321.4e-49253543
STKc_GRK6cd056303.2e-50253543
STKc_MAPKKKcd066061.2e-39253522
STKc_Cdc7_likecd066272.6e-18253522
STKc_MEKK3cd066511.5e-09253492
STKc_MAPKcd078341.5e-09253546
STKc_Pho85cd078362.1e-13253522
STKc_CDK5cd078392.9e-08253522
STKc_CDK7cd078411.6e-13253517
STKc_CDK8_likecd078421.5e-06253522
STKc_CCRKcd078321e-12253523
STKc_NLKcd078535.4e-06253582
STKc_TDY_MAPK_plantcd078596.3e-07253565
STKc_CDK2_3cd078602.2e-08253522
STKc_CDK1_eukcd078616.4e-14253552
STKc_CDK4cd078632.7e-06253522
STKc_MPK1cd078573.6e-06253547
STKc_Nekcd082157.6e-45253522
STKc_Nek2cd082174.1e-14253522
STKc_Nek1cd082181.1e-20253516
STKc_Nek3cd082192.8e-26253516
STKc_Nek8cd082205.8e-12253522
STKc_Nek9cd082215.6e-11253498
STKc_Nek11cd082226.8e-17253522
STKc_Nek4cd082234.8e-23253522
STKc_Nek5cd082258.7e-22253522
STKc_Nek10cd085282.7e-08253500
STKc_FA2-likecd085293e-14253505
STKc_CNK2-likecd085307.1e-15253516
PTKc_Axl_likecd050350.0006254517
PTKc_Tyro3cd050746e-05254517
PTKc_Tyk2_rpt2cd050804e-05254508
PTKc_Jak2_Jak3_rpt2cd050815.3e-06254518
STKc_CMGCcd051183.1e-16254522
STKc_PKNcd055895.4e-140254585
STKc_LATS1cd056251.7e-21254590
STKc_MAPKKK_Bck1_likcd066291e-10254522
STKc_MST4cd066408.6e-08254543
STKc_MST3cd066412.5e-07254543
STKc_CDK_likecd078292.4e-16254522
STKc_MAK_likecd078301.3e-13254522
STKc_MOKcd078311e-11254522
STKc_CDK1_likecd078353.7e-09254552
STKc_CDK4_6_likecd078381.9e-11254522
STKc_CDK9_likecd078406e-12254522
STKc_Sty1_Hog1cd078565.7e-06254546
PK_STRADcd082169.9e-05255541
PK_STRAD_alphacd082276.5e-05255591
STKc_MEKK4cd066262.6e-13256522
STKc_RSK_Ncd055824.1e-81257585
STKc_p70S6Kcd055843.8e-96257587
STKc_Rim15_likecd056111.3e-17257528
PTKccd001922.3e-12258512
PTKc_Ack_likecd050403.7e-06258499
PTKc_Fes_likecd050411.2e-08258487
PTKc_c-roscd050440.00029258515
PTKc_Tiecd050470.00052258494
PTKc_Met_Roncd050580.00015258519
PTK_Jak1_rpt1cd050770.00031258517
PTK_Jak2_Jak3_rpt1cd050780.00025258530
PTKc_Fescd050843.2e-06258514
PTKc_Fercd050854.6e-06258522
PTKc_Aatyk1_Aatyk3cd050870.0003258513
PTKc_Sykcd051163.5e-06258527
STKc_PKCcd055706.4e-263258585
STKc_PKBcd055712.7e-123258587
STKc_SGKcd055751.1e-123258585
STKc_aPKCcd055888.7e-270258586
STKc_nPKC_etacd055901.3e-144258586
STKc_nPKC_epsiloncd055911.3e-156258586
STKc_nPKC_theta_deltcd055924e-134258587
STKc_PKB_gammacd055933.2e-101258594
STKc_PKB_betacd055951.1e-113258587
STKc_SGK1cd056023.8e-98258587
STKc_SGK2cd056033.8e-105258586
STKc_PKB_alphacd055949.2e-113258588
STKc_SGK3cd056048.8e-104258587
STKc_aPKC_zetacd056171.2e-272258586
STKc_aPKC_iotacd05618258586
STKc_nPKC_thetacd056191.1e-115258587
STKc_nPKC_deltacd056206.2e-109258587
STKc_MAPKKK_Byr2_likcd066281.2e-15258522
STKc_MEKK1cd066305.6e-10258523
STKc_YSK4cd066319.9e-10258522
STKc_MEKK1_plantcd066321.5e-14258522
STKc_beta_ARKcd056063.2e-48259542
STKc_GRK3cd056333.1e-39259543
PKccd001805.6e-72260520
PTKc_Aatykcd050422.7e-05260508
PTKc_Zap-70cd051152.4e-05260521
STKc_AGCcd051233.4e-149260522
STKc_cGK_PKGcd055726.5e-74260529
STKc_GRKcd055771.5e-56260542
STKc_YPK1_likecd055851.3e-96260584
STKc_Sck1_likecd055863.4e-81260584
STKc_GRK7cd056071.1e-46260542
STKc_GRK1cd056082e-56260542
STKc_MAST_likecd055792.7e-62260527
STKc_SLK_likecd066111.2e-12260538
PTK_Rykcd050430.00029271473
PB1pfam005649.9e-1625108
C1_1pfam001301e-20141193
Pkinasepfam000691e-86254522
Pkinase_Cpfam004337.8e-13542588
PB1smart006661.5e-2525106
C1smart001091.1e-15141190
Pkinase_Tyrpfam077142.8e-16254522
TyrKcsmart002192.2e-13254522
STYKcsmart002217.4e-85254522
S_TKcsmart002201.8e-104264522
S_TK_Xsmart001331.3e-20523586

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_042323Polymorphismp.ARG130CYSN/A
Swiss-ProtVAR_042322Polymorphismp.PRO118LEUN/A



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