Results for the protein: P41743

Results for the Protein: P41743

239938658

5584

PRKCI

NCBI, UniProt

KPCI_HUMAN RecName: Full=Protein kinase C iota type; AltName: Full=Atypical protein kinase C-lambda/iota; Short=PRKC-lambda/iota; Short=aPKC-lambda/iota; AltName: Full=nPKC-iota

			0 2 0 0 2

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Swiss-Prot Protein: P41743

Identical to: NP_002731

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PB1_aPKC	cd06404	1.6e-67	26	108
C1	cd00029	1.6e-17	141	190
STKc_ROCK	cd05596	1.6e-39	206	586
STKc_ROCK2	cd05621	9e-37	206	586
STKc_ROCK1	cd05622	7.3e-34	206	587
STKc_TAO1	cd06635	1.4e-05	225	540
STKc_myosinIIIB	cd06639	7.7e-08	227	523
STKc_PAK_II	cd06648	9.3e-12	231	530
STKc_PAK1	cd06654	4.8e-07	232	546
STKc_PAK2	cd06655	7.4e-08	233	547
STKc_PAK3	cd06656	1.1e-07	233	548
STKc_PAK_I	cd06647	1.1e-07	234	544
STKc_JNK3	cd07874	0.00074	235	591
STKc_p38alpha_MAPK14	cd07877	2.9e-05	235	565
STKc_JNK1	cd07875	0.00074	236	591
STKc_JNK	cd07850	5e-05	237	585
STKc_p38	cd07851	6e-06	237	541
STKc_p38gamma_MAPK12	cd07880	7e-06	237	565
STKc_p38beta_MAPK11	cd07878	0.00011	237	565
STKc_TAO	cd06607	1.1e-05	238	563
STKc_PAK	cd06614	2.9e-18	238	536
PTKc_EGFR_like	cd05057	0.00014	239	508
STKc_myosinIIIA	cd06638	6.3e-08	239	522
STKc_PAK4	cd06657	9.6e-07	239	536
STKc_PAK5	cd06658	2.4e-07	239	534
STKc_PAK6	cd06659	3.2e-09	239	545
STKc_MAP4K4_6	cd06636	7.6e-07	241	511
STKc_CDK9	cd07865	4.3e-07	241	522
PKc_MKK7	cd06618	5.9e-09	243	545
STKc_TAO2	cd06634	5.3e-06	243	541
STKc_PFTAIRE1	cd07869	2.4e-06	243	534
STKc_PFTAIRE2	cd07870	1.4e-08	243	522
PTKc_FGFR4	cd05099	0.001	244	542
STKc_STK10_LOK	cd06644	2.9e-09	244	543
STKc_MAP4K3	cd06645	2.8e-09	244	510
STKc_MAP4K5	cd06646	3.7e-08	244	510
STKc_ASK	cd06624	4.2e-17	245	522
PTK_HER3	cd05111	2.7e-05	246	508
STKc_CDK10	cd07845	1e-09	246	541
PTKc_ALK_LTK	cd05036	8.3e-06	247	522
PTKc_FAK	cd05056	3.1e-06	247	521
PTKc_Tie2	cd05088	1.4e-05	247	518
STKc_MAPK4_6	cd07854	3.5e-05	247	560
STKc_CDK12	cd07864	4.4e-09	247	522
STKc_BUR1	cd07866	1.5e-06	247	522
PTKc_Trk	cd05049	0.0007	248	519
PTKc_Abl	cd05052	1.1e-06	248	526
PTKc_InsR	cd05061	0.00088	248	527
PTKc_EphR_A10	cd05064	0.00031	248	497
PTKc_Frk_like	cd05068	2.8e-06	248	516
PTKc_Yes	cd05069	0.0009	248	517
PTKc_Fyn_Yrk	cd05070	0.00016	248	517
PTKc_Lyn	cd05072	0.00037	248	516
PTKc_Hck	cd05073	7.9e-05	248	496
PTKc_Csk	cd05082	3.7e-06	248	516
PKc_MEK2	cd06649	1e-06	248	596
PKc_MEK1	cd06650	5.2e-06	248	593
STKc_ERK5	cd07855	5.1e-05	248	546
STKc_TEY_MAPK_plant	cd07858	7.1e-08	248	565
STKc_PCTAIRE1	cd07873	7.7e-07	248	534
STKc_PCTAIRE2	cd07872	4.8e-08	248	542
PTKc_InsR_like	cd05032	0.00045	249	516
PTKc_EphR	cd05033	0.0001	249	497
PTKc_Csk_like	cd05039	1.7e-05	249	488
PTKc_FGFR	cd05053	0.00017	249	486
PTKc_Tec_like	cd05059	7.1e-08	249	506
PTKc_EphR_B	cd05065	0.00024	249	497
PTKc_EphR_A	cd05066	0.00073	249	497
PTKc_Jak1_rpt2	cd05079	0.00021	249	517
PTKc_Chk	cd05083	0.00014	249	517
PTKc_EGFR	cd05108	0.00049	249	587
PTKc_Btk_Bmx	cd05113	1.4e-09	249	517
PTKc_Tec_Rlk	cd05114	3.9e-07	249	515
PTKc_Itk	cd05112	5.4e-07	249	511
PKc_MKK4	cd06616	2.7e-08	249	536
PKc_MAPKK_Byr1_like	cd06620	4.3e-09	249	533
STKc_SLK	cd06643	1.6e-09	249	534
STKc_MST1_2	cd06612	1.3e-15	250	511
STKc_MAP4K3_like	cd06613	5.3e-16	250	521
STKc_PCTAIRE_like	cd07844	7.2e-15	250	547
PTKc_Tie1	cd05089	0.00068	251	517
STKc_myosinIII_like	cd06608	9e-14	251	522
STKc_TNIK	cd06637	9.8e-09	251	522
STKc_MAPK15	cd07852	1.3e-07	251	560
STKc_PCTAIRE3	cd07871	8.5e-09	251	522
STKc_Nek6_Nek7	cd08224	3.9e-10	251	518
STKc_Nek6	cd08228	1.9e-08	251	519
STKc_Nek7	cd08229	1e-10	251	519
PTKc_Src_like	cd05034	6.1e-05	252	516
PTKc_Jak_rpt2	cd05038	1.2e-06	252	526
PTKc_Srm_Brk	cd05148	6.8e-06	252	514
STKc_ROCK_NDR_like	cd05573	1.1e-66	252	585
STKc_phototropin_lik	cd05574	2e-58	252	548
STKc_PKA	cd05580	1.5e-101	252	555
STKc_PDK1	cd05581	1.1e-74	252	522
STKc_DMPK_like	cd05597	5.7e-59	252	585
STKc_NDR_like	cd05599	4e-22	252	588
STKc_Sid2p_Dbf2p	cd05600	3.1e-22	252	586
STKc_CRIK	cd05601	1.8e-42	252	585
STKc_LATS	cd05598	3.6e-36	252	590
STKc_MAST	cd05609	3.7e-59	252	553
STKc_PRKX_like	cd05612	3.2e-81	252	556
STKc_MRCK_alpha	cd05623	3.5e-38	252	586
STKc_MRCK_beta	cd05624	2.9e-42	252	585
STKc_LATS2	cd05626	4.3e-28	252	590
STKc_NDR2	cd05627	4.3e-28	252	593
STKc_NDR1	cd05628	1.2e-25	252	593
STKc_NDR_like_fungal	cd05629	6.5e-34	252	593
PKc_MAPKK	cd06605	6.2e-14	252	527
STKc_MST3_like	cd06609	3.9e-15	252	540
STKc_OSR1_SPAK	cd06610	2.6e-13	252	522
PKc_MKK3_6	cd06617	1.3e-09	252	541
PKc_MKK5	cd06619	2.9e-06	252	534
PKc_MAPKK_PBS2_like	cd06622	9.1e-09	252	592
PKc_MAPKK_plant_like	cd06623	2e-19	252	527
STKc_MEKK3_like	cd06625	2.7e-13	252	516
PKc_MAPKK_Pek1_like	cd06621	2.9e-09	252	536
STKc_STK25-YSK1	cd06642	3.7e-09	252	537
STKc_MEKK2	cd06652	1.2e-06	252	499
STKc_MEKK3_like_1	cd06653	2.5e-08	252	497
PKc_MEK	cd06615	2.8e-11	252	540
STKc_NAK1_like	cd06917	7.3e-14	252	534
STKc_CDKL	cd07833	1.2e-11	252	522
STKc_CdkB_plant	cd07837	5.3e-11	252	523
STKc_CDC2L1	cd07843	1.2e-07	252	522
STKc_CDKL2_3	cd07846	8.2e-10	252	522
STKc_CDKL1_4	cd07847	6.3e-15	252	522
STKc_CDKL5	cd07848	1.3e-06	252	522
STKc_ERK1_2_like	cd07849	5.5e-06	252	549
STKc_CDK6	cd07862	8.2e-06	252	522
SPS1	COG0515	2.6e-54	252	593
PKc_STE	cd05122	1.6e-24	253	510
STKc_Yank1	cd05578	2e-75	253	522
STKc_MSK_N	cd05583	4.6e-104	253	541
STKc_cPKC	cd05587	2e-150	253	586
STKc_GRK4_like	cd05605	1.5e-60	253	543
STKc_MSK1_N	cd05613	1e-84	253	541
STKc_MSK2_N	cd05614	1.8e-97	253	587
STKc_cPKC_beta	cd05616	8.8e-143	253	586
STKc_cPKC_alpha	cd05615	8.1e-140	253	586
STKc_GRK4	cd05631	2.4e-50	253	543
STKc_GRK5	cd05632	1.4e-49	253	543
STKc_GRK6	cd05630	3.2e-50	253	543
STKc_MAPKKK	cd06606	1.2e-39	253	522
STKc_Cdc7_like	cd06627	2.6e-18	253	522
STKc_MEKK3	cd06651	1.5e-09	253	492
STKc_MAPK	cd07834	1.5e-09	253	546
STKc_Pho85	cd07836	2.1e-13	253	522
STKc_CDK5	cd07839	2.9e-08	253	522
STKc_CDK7	cd07841	1.6e-13	253	517
STKc_CDK8_like	cd07842	1.5e-06	253	522
STKc_CCRK	cd07832	1e-12	253	523
STKc_NLK	cd07853	5.4e-06	253	582
STKc_TDY_MAPK_plant	cd07859	6.3e-07	253	565
STKc_CDK2_3	cd07860	2.2e-08	253	522
STKc_CDK1_euk	cd07861	6.4e-14	253	552
STKc_CDK4	cd07863	2.7e-06	253	522
STKc_MPK1	cd07857	3.6e-06	253	547
STKc_Nek	cd08215	7.6e-45	253	522
STKc_Nek2	cd08217	4.1e-14	253	522
STKc_Nek1	cd08218	1.1e-20	253	516
STKc_Nek3	cd08219	2.8e-26	253	516
STKc_Nek8	cd08220	5.8e-12	253	522
STKc_Nek9	cd08221	5.6e-11	253	498
STKc_Nek11	cd08222	6.8e-17	253	522
STKc_Nek4	cd08223	4.8e-23	253	522
STKc_Nek5	cd08225	8.7e-22	253	522
STKc_Nek10	cd08528	2.7e-08	253	500
STKc_FA2-like	cd08529	3e-14	253	505
STKc_CNK2-like	cd08530	7.1e-15	253	516
PTKc_Axl_like	cd05035	0.0006	254	517
PTKc_Tyro3	cd05074	6e-05	254	517
PTKc_Tyk2_rpt2	cd05080	4e-05	254	508
PTKc_Jak2_Jak3_rpt2	cd05081	5.3e-06	254	518
STKc_CMGC	cd05118	3.1e-16	254	522
STKc_PKN	cd05589	5.4e-140	254	585
STKc_LATS1	cd05625	1.7e-21	254	590
STKc_MAPKKK_Bck1_lik	cd06629	1e-10	254	522
STKc_MST4	cd06640	8.6e-08	254	543
STKc_MST3	cd06641	2.5e-07	254	543
STKc_CDK_like	cd07829	2.4e-16	254	522
STKc_MAK_like	cd07830	1.3e-13	254	522
STKc_MOK	cd07831	1e-11	254	522
STKc_CDK1_like	cd07835	3.7e-09	254	552
STKc_CDK4_6_like	cd07838	1.9e-11	254	522
STKc_CDK9_like	cd07840	6e-12	254	522
STKc_Sty1_Hog1	cd07856	5.7e-06	254	546
PK_STRAD	cd08216	9.9e-05	255	541
PK_STRAD_alpha	cd08227	6.5e-05	255	591
STKc_MEKK4	cd06626	2.6e-13	256	522
STKc_RSK_N	cd05582	4.1e-81	257	585
STKc_p70S6K	cd05584	3.8e-96	257	587
STKc_Rim15_like	cd05611	1.3e-17	257	528
PTKc	cd00192	2.3e-12	258	512
PTKc_Ack_like	cd05040	3.7e-06	258	499
PTKc_Fes_like	cd05041	1.2e-08	258	487
PTKc_c-ros	cd05044	0.00029	258	515
PTKc_Tie	cd05047	0.00052	258	494
PTKc_Met_Ron	cd05058	0.00015	258	519
PTK_Jak1_rpt1	cd05077	0.00031	258	517
PTK_Jak2_Jak3_rpt1	cd05078	0.00025	258	530
PTKc_Fes	cd05084	3.2e-06	258	514
PTKc_Fer	cd05085	4.6e-06	258	522
PTKc_Aatyk1_Aatyk3	cd05087	0.0003	258	513
PTKc_Syk	cd05116	3.5e-06	258	527
STKc_PKC	cd05570	6.4e-263	258	585
STKc_PKB	cd05571	2.7e-123	258	587
STKc_SGK	cd05575	1.1e-123	258	585
STKc_aPKC	cd05588	8.7e-270	258	586
STKc_nPKC_eta	cd05590	1.3e-144	258	586
STKc_nPKC_epsilon	cd05591	1.3e-156	258	586
STKc_nPKC_theta_delt	cd05592	4e-134	258	587
STKc_PKB_gamma	cd05593	3.2e-101	258	594
STKc_PKB_beta	cd05595	1.1e-113	258	587
STKc_SGK1	cd05602	3.8e-98	258	587
STKc_SGK2	cd05603	3.8e-105	258	586
STKc_PKB_alpha	cd05594	9.2e-113	258	588
STKc_SGK3	cd05604	8.8e-104	258	587
STKc_aPKC_zeta	cd05617	1.2e-272	258	586
STKc_aPKC_iota	cd05618		258	586
STKc_nPKC_theta	cd05619	1.1e-115	258	587
STKc_nPKC_delta	cd05620	6.2e-109	258	587
STKc_MAPKKK_Byr2_lik	cd06628	1.2e-15	258	522
STKc_MEKK1	cd06630	5.6e-10	258	523
STKc_YSK4	cd06631	9.9e-10	258	522
STKc_MEKK1_plant	cd06632	1.5e-14	258	522
STKc_beta_ARK	cd05606	3.2e-48	259	542
STKc_GRK3	cd05633	3.1e-39	259	543
PKc	cd00180	5.6e-72	260	520
PTKc_Aatyk	cd05042	2.7e-05	260	508
PTKc_Zap-70	cd05115	2.4e-05	260	521
STKc_AGC	cd05123	3.4e-149	260	522
STKc_cGK_PKG	cd05572	6.5e-74	260	529
STKc_GRK	cd05577	1.5e-56	260	542
STKc_YPK1_like	cd05585	1.3e-96	260	584
STKc_Sck1_like	cd05586	3.4e-81	260	584
STKc_GRK7	cd05607	1.1e-46	260	542
STKc_GRK1	cd05608	2e-56	260	542
STKc_MAST_like	cd05579	2.7e-62	260	527
STKc_SLK_like	cd06611	1.2e-12	260	538
PTK_Ryk	cd05043	0.00029	271	473
PB1	pfam00564	9.9e-16	25	108
C1_1	pfam00130	1e-20	141	193
Pkinase	pfam00069	1e-86	254	522
Pkinase_C	pfam00433	7.8e-13	542	588
PB1	smart00666	1.5e-25	25	106
C1	smart00109	1.1e-15	141	190
Pkinase_Tyr	pfam07714	2.8e-16	254	522
TyrKc	smart00219	2.2e-13	254	522
STYKc	smart00221	7.4e-85	254	522
S_TKc	smart00220	1.8e-104	264	522
S_TK_X	smart00133	1.3e-20	523	586

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_042323	Polymorphism	p.ARG130CYS	N/A
Swiss-Prot	VAR_042322	Polymorphism	p.PRO118LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258