Results for the protein: P41252

Results for the Protein: P41252

239938717

3376

IARS

NCBI, UniProt

SYIC_HUMAN RecName: Full=Isoleucine--tRNA ligase, cytoplasmic; AltName: Full=Isoleucyl-tRNA synthetase; Short=IRS; Short=IleRS

			0 3 0 0 3

Tips:

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Default View: IleS - COG0060 ValS - COG0525 LeuS - COG0495 tRNA-synt_1 - pfam00133 IleRS_core - cd00818 ValRS_core - cd00817 Ile_Leu_Val_MetRS_co - cd00668 LeuRS_core - cd00812 MetG - COG0143 MetRS_core - cd00814 Anticodon_Ia_Ile_ABE - cd07961 Anticodon_Ia_like - cd07375 Anticodon_Ia_Val - cd07962 Anticodon_1 - pfam08264	Swiss-Prot Protein: P41252 Identical to: NP_038203, NP_002152 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ValS	COG0525	4.8e-23	1	991
LeuS	COG0495	2e-05	5	918
IleRS_core	cd00818		39	640
ValRS_core	cd00817	1.7e-22	39	640
Ile_Leu_Val_MetRS_co	cd00668	4.6e-131	40	640
LeuRS_core	cd00812	1.2e-12	47	640
MetG	COG0143	0.001	314	823
MetRS_core	cd00814	0.0002	339	640
Anticodon_Ia_Ile_ABE	cd07961	2.8e-94	640	833
Anticodon_Ia_like	cd07375	7.1e-08	642	770
Anticodon_Ia_Val	cd07962	5.3e-10	647	784
tRNA-synt_1	pfam00133		17	639
Anticodon_1	pfam08264	2.4e-25	693	851

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_057952	Polymorphism	p.LYS1182GLU	N/A
Swiss-Prot	VAR_057951	Polymorphism	p.MET769ILE	N/A
Swiss-Prot	VAR_058300	Polymorphism	p.THR684MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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