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Results for the Protein: P00749
254763341

UROK_HUMAN RecName: Full=Urokinase-type plasminogen activator; Short=U-plasminogen activator; Short=uPA; Contains: RecName: Full=Urokinase-type plasminogen activator long chain A; Contains: RecName: Full=Urokinase-type plasminogen activator short chain A; Contains: RecName: Full=Urokinase-type plasminogen activator chain B; Flags: Precursor

Known Diseases associated with this Protein:
  ALZHEIMER DISEASE, LATE-ONSET, SUSCEPTIBILITY TO
1
5
1
2
3
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Default View:

KR - cd00108
KR - smart00130
Kringle - pfam00051
Tryp_SPc - smart00020
Tryp_SPc - cd00190
Trypsin - pfam00089


Swiss-Prot Protein: P00749
Identical to: NP_002649
   Default View:





Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
KRcd001081e-4067152
Tryp_SPccd001908.1e-105179422
Kringlepfam000511.4e-3770151
Trypsinpfam000896.8e-98179419
KRsmart001304.6e-3668153
Tryp_SPcsmart000209.8e-92178419

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_013102Polymorphismp.ILE214METN/A
dbSNPrs2227564 Polymorphismp.LEU141PRON/A
dbSNPrs2227567 Polymorphismp.LYS231GLNN/A
Swiss-ProtVAR_006722Polymorphismp.PRO141LEUN/A
Swiss-ProtVAR_038730Polymorphismp.VAL15LEUN/A
OMIM191840.0001 Diseasep.PRO141LEUALZHEIMER DISEASE, LATE-ONSET, SUSCEPTIBILITY TO



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