Results for the protein: Q13131

Results for the Protein: Q13131

254763436

5562

PRKAA1

NCBI, UniProt

AAPK1_HUMAN RecName: Full=5'-AMP-activated protein kinase catalytic subunit alpha-1; Short=AMPK subunit alpha-1; AltName: Full=Acetyl-CoA carboxylase kinase; Short=ACACA kinase; AltName: Full=Hydroxymethylglutaryl-CoA reductase kinase; Short=HMGCR kinase; AltName: Full=Tau-protein kinase PRKAA1

			0 2 0 0 2

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Swiss-Prot Protein: Q13131

Identical to: NP_006242

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK1	cd05622	7.9e-09	1	338
STKc_TAO1	cd06635	2.4e-06	1	289
STKc_myosinIIIB	cd06639	5.2e-09	1	280
STKc_TAO3	cd06633	8.6e-05	3	310
STKc_PAK5	cd06658	1.6e-08	3	295
STKc_ROCK2	cd05621	9.5e-10	4	337
PTKc_PDGFR	cd05055	0.00016	5	284
STKc_PAK6	cd06659	9.5e-13	5	298
STKc_PAK_II	cd06648	9.2e-15	6	291
STKc_PAK4	cd06657	9.8e-09	6	305
PTKc_DDR2	cd05095	6.9e-06	8	281
PTKc_DDR_like	cd05097	3.7e-05	8	281
STKc_JNK3	cd07874	2.2e-06	8	358
STKc_p38alpha_MAPK14	cd07877	6.7e-09	8	317
STKc_TAO	cd06607	2.3e-06	9	324
STKc_TAO2	cd06634	3.6e-06	9	315
STKc_MAP4K4_6	cd06636	1.1e-06	10	261
STKc_p38	cd07851	7.6e-12	10	327
STKc_JNK1	cd07875	2.7e-06	10	326
STKc_p38beta_MAPK11	cd07878	1.5e-08	10	323
STKc_p38delta_MAPK13	cd07879	1.9e-05	10	323
STKc_p38gamma_MAPK12	cd07880	1e-09	10	323
PTKc_FGFR1	cd05098	2.8e-05	11	288
PTKc_FGFR3	cd05100	0.00015	11	307
STKc_PAK2	cd06655	3.8e-10	11	308
STKc_JNK	cd07850	4e-09	11	318
STKc_JNK2	cd07876	6.6e-08	11	320
PKc_MKK7	cd06618	3.5e-10	12	310
STKc_PAK1	cd06654	1.3e-09	12	307
PTKc_FGFR2	cd05101	2.7e-05	13	291
STKc_PAK	cd06614	1.3e-18	13	287
STKc_STK10_LOK	cd06644	8.1e-08	13	307
PTKc_EGFR_like	cd05057	4.9e-08	14	290
STKc_CDK9	cd07865	3.1e-12	14	279
PTKc_FGFR4	cd05099	1.6e-06	16	293
STKc_PAK_I	cd06647	7.3e-13	16	305
STKc_PAK3	cd06656	3.7e-10	16	309
PTKc_FGFR	cd05053	8.6e-07	17	288
STKc_MAP4K3	cd06645	1.1e-08	17	278
STKc_MAP4K5	cd06646	6.8e-09	17	278
STKc_BUR1	cd07866	1.6e-14	18	279
PTKc_ALK_LTK	cd05036	4.3e-06	20	281
PTKc_Tie2	cd05088	1.3e-06	20	299
PTK_HER3	cd05111	1e-08	20	290
PKc_MAPKK_plant_like	cd06623	3.4e-20	20	285
STKc_TNIK	cd06637	6.8e-08	20	261
STKc_CDK10	cd07845	2.5e-13	20	295
STKc_CDK12	cd07864	4.1e-13	20	279
STKc_PCTAIRE1	cd07873	3.4e-09	20	291
STKc_PCTAIRE2	cd07872	2.8e-10	20	298
PTKc_Ror	cd05048	1.7e-09	21	278
PTKc_Trk	cd05049	5e-10	21	277
PTKc_Musk	cd05050	2.4e-08	21	276
PTKc_Abl	cd05052	8.3e-11	21	283
PTKc_FAK	cd05056	1.9e-10	21	283
PTKc_InsR	cd05061	8.6e-07	21	294
PTKc_IGF-1R	cd05062	3e-05	21	275
PTKc_EphR_A2	cd05063	8.4e-07	21	287
PTKc_Lck_Blk	cd05067	2e-07	21	311
PTKc_Frk_like	cd05068	6.7e-17	21	279
PTKc_Fyn_Yrk	cd05070	3.7e-08	21	286
PTKc_Src	cd05071	9.7e-08	21	280
PTKc_Yes	cd05069	1.8e-09	21	283
PTKc_Lyn	cd05072	1.2e-08	21	279
PTKc_Hck	cd05073	8.7e-08	21	279
PTKc_Csk	cd05082	3.9e-08	21	280
PTKc_Ror1	cd05090	2.7e-07	21	278
PTKc_Ror2	cd05091	1.1e-05	21	278
PTKc_TrkA	cd05092	2.2e-08	21	285
PTKc_TrkB	cd05093	6.1e-08	21	288
PTKc_TrkC	cd05094	2.6e-07	21	354
PTKc_DDR1	cd05096	0.00016	21	281
PTKc_EphR_A10	cd05064	1e-07	21	283
PKc_MEK2	cd06649	1.2e-05	21	358
PKc_MEK1	cd06650	8.3e-05	21	356
STKc_ASK	cd06624	2e-12	21	279
STKc_TEY_MAPK_plant	cd07858	9.3e-13	21	317
PTKc_InsR_like	cd05032	9.4e-09	22	275
PTKc_EphR	cd05033	3.1e-09	22	287
PTKc_Jak_rpt2	cd05038	1.1e-11	22	278
PTKc_Csk_like	cd05039	6.8e-07	22	244
PTKc_EphR_B	cd05065	1.5e-06	22	287
PTKc_Chk	cd05083	5.8e-10	22	280
PTKc_EphR_A	cd05066	3.7e-06	22	287
PTKc_EGFR	cd05108	3.4e-07	22	321
PTKc_Itk	cd05112	2.4e-10	22	278
PTKc_Btk_Bmx	cd05113	1.1e-15	22	278
PTKc_Tec_Rlk	cd05114	6.4e-13	22	278
STKc_SLK	cd06643	3.6e-07	22	293
STKc_ERK1_2_like	cd07849	2e-10	22	328
PTKc_Jak1_rpt2	cd05079	3.8e-06	23	283
STKc_GRK4	cd05631	2.5e-08	23	292
PKc_MKK4	cd06616	1.4e-07	23	304
STKc_myosinIIIA	cd06638	6.2e-09	23	279
STKc_PCTAIRE_like	cd07844	4.5e-16	23	279
STKc_ERK5	cd07855	1.1e-09	23	311
STKc_PFTAIRE1	cd07869	2.6e-06	23	292
STKc_PFTAIRE2	cd07870	9.7e-09	23	279
STKc_PCTAIRE3	cd07871	6.2e-10	23	279
PTKc_Tie1	cd05089	1.2e-06	24	300
STKc_Nek6_Nek7	cd08224	4e-11	24	282
STKc_Nek6	cd08228	5.2e-08	24	284
STKc_Nek7	cd08229	3e-10	24	277
PTKc_DDR	cd05051	0.001	25	281
STKc_ROCK_NDR_like	cd05573	3.6e-15	25	324
STKc_phototropin_lik	cd05574	4.3e-12	25	299
STKc_PKA	cd05580	1.1e-36	25	298
STKc_PDK1	cd05581	9.3e-47	25	279
STKc_DMPK_like	cd05597	8.4e-10	25	336
STKc_Sid2p_Dbf2p	cd05600	3.3e-11	25	327
STKc_CRIK	cd05601	8.5e-12	25	338
STKc_LATS	cd05598	9.5e-10	25	339
STKc_MAST	cd05609	3.5e-19	25	296
STKc_PRKX_like	cd05612	5.6e-36	25	295
STKc_MRCK_alpha	cd05623	4e-09	25	337
STKc_MRCK_beta	cd05624	7.6e-09	25	336
STKc_LATS1	cd05625	7.7e-07	25	345
STKc_LATS2	cd05626	4.7e-06	25	345
STKc_NDR2	cd05627	8.7e-07	25	371
STKc_NDR1	cd05628	2e-07	25	345
STKc_NDR_like_fungal	cd05629	3.7e-06	25	352
STKc_myosinIII_like	cd06608	2.8e-12	25	279
STKc_OSR1_SPAK	cd06610	3.7e-15	25	279
STKc_MST3_like	cd06609	2.7e-13	25	298
PKc_MEK	cd06615	1.2e-09	25	298
PKc_MKK5	cd06619	9e-05	25	308
PKc_MAPKK_Pek1_like	cd06621	2.1e-11	25	288
STKc_STK25-YSK1	cd06642	1.5e-10	25	306
PKc_MAPKK_PBS2_like	cd06622	3.6e-09	25	329
STKc_MEKK2	cd06652	4.3e-11	25	280
STKc_NAK1_like	cd06917	7.1e-11	25	287
STKc_CDKL	cd07833	4e-13	25	279
STKc_CdkB_plant	cd07837	9e-15	25	280
STKc_CDK8_like	cd07842	1.7e-10	25	279
STKc_CDKL2_3	cd07846	5.8e-12	25	279
STKc_CDKL1_4	cd07847	5.2e-17	25	279
STKc_MAPK4_6	cd07854	5e-08	25	317
STKc_CDK6	cd07862	2.7e-06	25	304
SPS1	COG0515	1.2e-73	25	463
PTKc_RET	cd05045	1e-06	26	290
PTKc_Jak2_Jak3_rpt2	cd05081	1.9e-09	26	305
PTKc_HER2	cd05109	1.3e-06	26	290
PKc_STE	cd05122	2e-27	26	278
STKc_Yank1	cd05578	2.9e-27	26	279
STKc_MSK_N	cd05583	8e-21	26	296
STKc_cPKC	cd05587	3.6e-33	26	334
STKc_GRK4_like	cd05605	6e-11	26	292
STKc_MSK1_N	cd05613	1e-11	26	292
STKc_MSK2_N	cd05614	1.3e-18	26	340
STKc_cPKC_alpha	cd05615	2.3e-23	26	354
STKc_cPKC_beta	cd05616	1.4e-17	26	334
STKc_GRK6	cd05630	1e-08	26	292
STKc_GRK5	cd05632	8.5e-09	26	292
STKc_MAPKKK	cd06606	5e-49	26	279
STKc_MAP4K3_like	cd06613	8.9e-14	26	278
STKc_Cdc7_like	cd06627	1.9e-21	26	279
STKc_MAPKKK_Byr2_lik	cd06628	4.4e-27	26	279
STKc_MAPKKK_Bck1_lik	cd06629	5.8e-15	26	279
STKc_MEKK1	cd06630	1.8e-12	26	280
STKc_YSK4	cd06631	5e-11	26	279
STKc_MEKK3	cd06651	1.1e-12	26	281
STKc_MEKK3_like_1	cd06653	5e-15	26	279
STKc_MAPK	cd07834	1.6e-13	26	325
STKc_CDK5	cd07839	5.7e-11	26	279
STKc_CDK7	cd07841	8.4e-18	26	284
STKc_Pho85	cd07836	9.1e-23	26	279
STKc_CDKL5	cd07848	1.2e-05	26	279
STKc_CCRK	cd07832	2.3e-17	26	280
STKc_NLK	cd07853	1.3e-08	26	351
STKc_MPK1	cd07857	6.8e-10	26	307
STKc_TDY_MAPK_plant	cd07859	1.8e-10	26	337
STKc_CDK1_euk	cd07861	1.5e-19	26	279
STKc_CDK4	cd07863	1.7e-09	26	279
STKc_CDK2_3	cd07860	1.8e-22	26	279
STKc_Nek	cd08215	7.3e-40	26	279
STKc_Nek2	cd08217	2.6e-17	26	279
STKc_Nek3	cd08219	5.6e-20	26	279
STKc_Nek8	cd08220	2.1e-23	26	279
STKc_Nek9	cd08221	4.5e-12	26	279
STKc_Nek4	cd08223	1.5e-12	26	279
STKc_Nek5	cd08225	2.1e-24	26	279
STKc_Nek11	cd08222	5.7e-18	26	279
STKc_Nek1	cd08218	9.3e-20	26	279
STKc_FA2-like	cd08529	1.5e-13	26	278
STKc_CNK2-like	cd08530	8.4e-12	26	279
STKc_Nek10	cd08528	9.4e-10	26	272
PTKc_Axl_like	cd05035	1.5e-07	27	287
PTKc_Tyro3	cd05074	1.6e-07	27	280
PTKc_Axl	cd05075	4.3e-05	27	287
STKc_CMGC	cd05118	2.4e-18	27	279
PTKc_Srm_Brk	cd05148	2.3e-10	27	280
STKc_PKN	cd05589	3.1e-19	27	337
STKc_MST1_2	cd06612	1.8e-15	27	279
STKc_MST4	cd06640	3.4e-13	27	305
STKc_MST3	cd06641	3e-09	27	306
STKc_CDK_like	cd07829	9e-23	27	279
STKc_MAK_like	cd07830	8.8e-18	27	279
STKc_MOK	cd07831	4e-14	27	279
STKc_CDK1_like	cd07835	3e-16	27	279
STKc_CDK4_6_like	cd07838	6.3e-16	27	279
STKc_CDK9_like	cd07840	6.3e-18	27	279
PTKc_Src_like	cd05034	1.9e-11	28	279
PTK_Ryk	cd05043	0.00058	28	246
PTKc_HER4	cd05110	2e-06	28	303
STKc_SLK_like	cd06611	1.8e-12	28	290
PKc_MAPKK_Byr1_like	cd06620	2.5e-08	28	308
STKc_Sty1_Hog1	cd07856	8.6e-11	28	311
PK_STRAD_alpha	cd08227	0.0008	28	381
PK_STRAD	cd08216	1.6e-07	28	289
PTKc_Tec_like	cd05059	4.1e-11	29	278
STKc_MEKK3_like	cd06625	1.1e-29	29	279
STKc_MEKK4	cd06626	8.3e-18	29	279
STKc_p70S6K	cd05584	7.2e-25	30	335
STKc_MEKK1_plant	cd06632	1.5e-13	30	279
STKc_CDC2L6	cd07867	1.3e-05	30	279
STKc_CDK8	cd07868	6.8e-05	30	279
PTKc	cd00192	3.3e-13	31	278
PTKc_Ack_like	cd05040	1.2e-11	31	285
PTKc_Fes_like	cd05041	1e-10	31	276
PTKc_c-ros	cd05044	6.4e-05	31	277
PTKc_Tie	cd05047	4.8e-06	31	277
PTKc_Met_Ron	cd05058	1.6e-06	31	282
PTKc_Syk_like	cd05060	3.8e-10	31	284
PTKc_Aatyk	cd05042	3e-06	31	258
PTK_Jak1_rpt1	cd05077	0.00069	31	274
PTK_Jak2_Jak3_rpt1	cd05078	0.00011	31	274
PTKc_Tyk2_rpt2	cd05080	4.7e-08	31	309
PTKc_Fes	cd05084	1.8e-10	31	279
PTKc_Fer	cd05085	9.7e-09	31	279
PTKc_Aatyk1_Aatyk3	cd05087	0.00063	31	279
PTKc_Syk	cd05116	9.4e-09	31	280
PTKc_Aatyk2	cd05086	7.7e-05	31	279
STKc_PKC	cd05570	1.6e-19	31	314
STKc_PKB	cd05571	8.2e-40	31	340
STKc_SGK	cd05575	1.8e-13	31	336
STKc_nPKC_eta	cd05590	2e-35	31	338
STKc_nPKC_epsilon	cd05591	1.9e-30	31	337
STKc_nPKC_theta_delt	cd05592	2.7e-37	31	341
STKc_PKB_gamma	cd05593	4.1e-25	31	341
STKc_PKB_alpha	cd05594	7.7e-29	31	339
STKc_PKB_beta	cd05595	4.6e-31	31	336
STKc_RSK_N	cd05582	1.9e-20	31	338
STKc_SGK1	cd05602	4e-10	31	358
STKc_SGK2	cd05603	7.1e-20	31	335
STKc_SGK3	cd05604	4.9e-18	31	358
STKc_aPKC	cd05588	1e-18	31	334
STKc_aPKC_zeta	cd05617	1e-11	31	334
STKc_aPKC_iota	cd05618	1.2e-09	31	323
STKc_nPKC_theta	cd05619	7e-23	31	356
STKc_nPKC_delta	cd05620	7.9e-18	31	341
PKc_MAPKK	cd06605	3.8e-12	31	284
PKc_MKK3_6	cd06617	2e-08	31	300
PTK_CCK4	cd05046	0.00021	32	261
PTKc_Zap-70	cd05115	2.1e-08	32	282
STKc_beta_ARK	cd05606	4.4e-12	32	301
STKc_GRK3	cd05633	7.5e-11	32	294
PKc	cd00180	9.1e-89	33	277
STKc_AGC	cd05123	7.4e-65	33	279
STKc_cGK_PKG	cd05572	4.5e-34	33	283
STKc_GRK	cd05577	5.3e-13	33	293
STKc_MAST_like	cd05579	1.9e-24	33	280
STKc_YPK1_like	cd05585	1.1e-33	33	327
STKc_Sck1_like	cd05586	2.3e-20	33	371
STKc_GRK7	cd05607	1.9e-10	33	297
STKc_GRK1	cd05608	9.5e-14	33	301
STKc_NDR_like	cd05599	1.2e-08	34	312
STKc_Rim15_like	cd05611	1.5e-09	36	282
STKc_CDC2L1	cd07843	1e-13	36	279
STKc_MAPK15	cd07852	1.6e-11	53	299
Pkinase	pfam00069	1e-98	27	279
Pkinase_Tyr	pfam07714	3.2e-18	27	279
STYKc	smart00221	1.8e-96	27	279
TyrKc	smart00219	2.7e-18	27	279
S_TKc	smart00220	1.5e-106	37	279

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_035622	Polymorphism	p.GLN16ARG	N/A
Swiss-Prot	VAR_058401	Polymorphism	p.MET10LEU	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258