Results for the protein: P58397

Results for the Protein: P58397

259016182

81792

ADAMTS12

NCBI, UniProt

ATS12_HUMAN RecName: Full=A disintegrin and metalloproteinase with thrombospondin motifs 12; Short=ADAM-TS 12; Short=ADAM-TS12; Short=ADAMTS-12; Flags: Precursor

			0 7 0 4 3

Tips:

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Default View: Pep_M12B_propep - pfam01562 ZnMc - cd00203 ZnMc_ADAMTS_like - cd04273 Reprolysin - pfam01421 ZnMc_adamalysin_II_l - cd04269 ZnMc_ADAM_like - cd04267 ZnMc_salivary_gland_ - cd04272 ZnMc_TACE_like - cd04270 TSP1 - smart00209 TSP_1 - pfam00090 ADAM_spacer1 - pfam05986	Swiss-Prot Protein: P58397 Identical to: NP_112217 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
ZnMc_ADAM_like	cd04267	3.6e-33	246	445
ZnMc_adamalysin_II_l	cd04269	2.5e-22	246	454
ZnMc_ADAMTS_like	cd04273	3.9e-122	246	453
ZnMc_salivary_gland_	cd04272	2.3e-09	248	453
ZnMc_TACE_like	cd04270	6.6e-05	251	459
Pep_M12B_propep	pfam01562	1.4e-46	12	195
Reprolysin	pfam01421	8.7e-17	246	456
TSP_1	pfam00090	2.2e-14	546	596
TSP_1	pfam00090	0.00018	946	996
TSP1	smart00209	3.2e-17	545	597
ADAM_spacer1	pfam05986	2.3e-57	702	813
TSP1	smart00209	1.9e-06	827	883
TSP1	smart00209	5.7e-08	947	997
TSP1	smart00209	7.4e-06	1474	1532

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs13362345	Polymorphism	p.ARG1000GLN	N/A
dbSNP	rs16891862	Polymorphism	p.GLN110GLU	N/A
dbSNP	rs112196098	Polymorphism	p.GLU1422GLN	N/A
Swiss-Prot	VAR_059762	Polymorphism	p.SER1591PRO	N/A
Swiss-Prot	VAR_058972	Polymorphism	p.THR1495ILE	N/A
dbSNP	rs117518215	Polymorphism	p.THR154MET	N/A
Swiss-Prot	VAR_059761	Polymorphism	p.TRP1177ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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