Results for the protein: P54756

Results for the Protein: P54756

259016353

2044

EPHA5

NCBI, UniProt

EPHA5_HUMAN RecName: Full=Ephrin type-A receptor 5; AltName: Full=Brain-specific kinase; AltName: Full=EPH homology kinase 1; Short=EHK-1; AltName: Full=EPH-like kinase 7; Short=EK7; Short=hEK7; Flags: Precursor

			0 12 0 2 10

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Swiss-Prot Protein: P54756

Identical to: NP_004430

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
FN3	cd00063	2.6e-21	469	559
PTKc_PDGFR_beta	cd05107	3e-09	555	937
PTKc_VEGFR	cd05054	1.7e-22	576	939
PTKc_CSF-1R	cd05106	2e-20	632	937
PTKc_PDGFR_alpha	cd05105	1.4e-13	634	938
PTKc_PDGFR	cd05055	4.4e-17	641	936
PTKc_Kit	cd05104	3e-13	641	936
STKc_PAK5	cd06658	5.3e-06	650	950
PTK_Tyk2_rpt1	cd05076	1.9e-07	653	933
STKc_TAO1	cd06635	1.1e-05	653	976
PTKc_FGFR1	cd05098	3.4e-35	654	943
STKc_myosinIIIB	cd06639	0.00023	654	937
PTKc_FGFR2	cd05101	2.9e-42	655	943
STKc_TAO3	cd06633	0.00041	655	976
STKc_PAK4	cd06657	5.8e-05	655	952
STKc_PAK6	cd06659	1.7e-07	655	956
STKc_JNK1	cd07875	0.00058	656	1027
STKc_TAO	cd06607	2.3e-05	658	976
STKc_TAO2	cd06634	2.1e-06	658	977
PTKc_FGFR4	cd05099	2.7e-41	659	962
STKc_PAK1	cd06654	0.00016	659	956
STKc_JNK2	cd07876	0.0001	659	1025
STKc_PAK3	cd06656	8.3e-05	660	951
STKc_p38	cd07851	1.2e-05	660	988
STKc_CDK9	cd07865	6.9e-06	660	950
STKc_JNK3	cd07874	0.00013	660	1021
STKc_p38beta_MAPK11	cd07878	0.00024	660	1010
STKc_p38gamma_MAPK12	cd07880	1.3e-05	660	1018
STKc_MAP4K4_6	cd06636	0.00021	661	936
PKc_MKK7	cd06618	4.2e-08	662	962
STKc_myosinIIIA	cd06638	0.00036	663	936
STKc_STK10_LOK	cd06644	3e-05	663	952
PTKc_FGFR3	cd05100	8.9e-30	664	981
PTKc_HER2	cd05109	6e-57	664	946
PTKc_HER4	cd05110	1.2e-50	664	960
PTKc_EGFR	cd05108	2.9e-51	664	988
STKc_PAK	cd06614	1.8e-11	664	946
STKc_ASK	cd06624	1.9e-08	664	936
STKc_MAP4K5	cd06646	0.00024	664	933
STKc_PAK_II	cd06648	8.7e-09	664	946
STKc_JNK	cd07850	2.7e-05	664	1013
STKc_MAP4K3	cd06645	2.5e-05	665	933
STKc_PCTAIRE2	cd07872	2.4e-05	665	980
STKc_PCTAIRE1	cd07873	0.00017	665	979
STKc_ERK5	cd07855	2.4e-05	666	1004
STKc_PCTAIRE3	cd07871	6e-06	666	955
PTKc_EGFR_like	cd05057	7.1e-73	667	946
PTKc_VEGFR3	cd05102	7.3e-21	667	939
PTKc_VEGFR2	cd05103	7.4e-18	667	939
PTK_HER3	cd05111	1.3e-49	667	946
STKc_PAK_I	cd06647	6.9e-05	667	954
STKc_PAK2	cd06655	0.00036	667	955
PTKc_ALK_LTK	cd05036	3.4e-67	668	934
PTKc_FAK	cd05056	6e-92	668	940
STKc_TNIK	cd06637	1.9e-05	668	936
STKc_CDK12	cd07864	3.1e-09	668	956
PTKc_InsR_like	cd05032	2.3e-70	669	934
PTKc_Src_like	cd05034	3.5e-103	669	935
PTKc_Csk_like	cd05039	2.9e-68	669	935
PTKc_Ror	cd05048	3.1e-62	669	935
PTKc_Trk	cd05049	1.7e-68	669	934
PTKc_Musk	cd05050	3e-72	669	934
PTKc_DDR	cd05051	1.9e-48	669	934
PTKc_Abl	cd05052	1.1e-81	669	936
PTKc_FGFR	cd05053	6.9e-39	669	937
PTKc_InsR	cd05061	1e-54	669	946
PTKc_IGF-1R	cd05062	1.8e-52	669	934
PTKc_EphR_A10	cd05064	1.2e-150	669	936
PTKc_EphR_A2	cd05063	4.9e-197	669	936
PTKc_Lck_Blk	cd05067	1e-79	669	935
PTKc_Frk_like	cd05068	2.5e-100	669	935
PTKc_Yes	cd05069	6.5e-75	669	935
PTKc_Fyn_Yrk	cd05070	5.1e-78	669	935
PTKc_Src	cd05071	7.8e-76	669	937
PTKc_Lyn	cd05072	7.6e-80	669	935
PTKc_Hck	cd05073	7.5e-80	669	935
PTKc_Csk	cd05082	4.5e-61	669	935
PTKc_Ror1	cd05090	2.4e-57	669	935
PTKc_Ror2	cd05091	1.4e-55	669	935
PTKc_TrkA	cd05092	9.1e-55	669	944
PTKc_TrkB	cd05093	2e-52	669	943
PTKc_TrkC	cd05094	4.8e-31	669	943
PTKc_DDR2	cd05095	8.4e-54	669	934
PTKc_DDR1	cd05096	7.6e-45	669	934
PTKc_DDR_like	cd05097	5.1e-52	669	934
PKc_MAPKK_Byr1_like	cd06620	1.3e-07	669	946
STKc_MST3	cd06641	4.9e-08	669	953
STKc_STK25-YSK1	cd06642	1.2e-08	669	953
STKc_MST4	cd06640	1.9e-08	669	953
STKc_SLK	cd06643	5.4e-06	669	961
STKc_TEY_MAPK_plant	cd07858	8e-07	669	999
PTKc_Jak_rpt2	cd05038	2.4e-71	670	936
PTKc_EphR	cd05033	1.1e-226	670	936
PTK_Ryk	cd05043	1.7e-23	670	935
PTKc_Tec_like	cd05059	3.6e-76	670	933
PTKc_EphR_B	cd05065	5.7e-199	670	936
PTKc_Jak1_rpt2	cd05079	2.3e-46	670	936
PTKc_Jak2_Jak3_rpt2	cd05081	3.9e-44	670	936
PTKc_EphR_A	cd05066	3.6e-228	670	936
PTKc_Chk	cd05083	5.1e-69	670	935
PTKc_Tie2	cd05088	1.9e-46	670	961
PTKc_Itk	cd05112	3.4e-72	670	933
PTKc_Btk_Bmx	cd05113	6.4e-75	670	933
PTKc_Tec_Rlk	cd05114	2.5e-76	670	933
PKc_MKK4	cd06616	3e-07	670	956
STKc_MAPK15	cd07852	8.8e-06	670	985
STKc_Sty1_Hog1	cd07856	1.8e-06	670	984
STKc_MAP4K3_like	cd06613	4e-11	671	933
PKc_MEK2	cd06649	0.0008	671	962
STKc_PCTAIRE_like	cd07844	1.2e-06	671	963
STKc_PFTAIRE2	cd07870	0.0002	671	960
PTK_CCK4	cd05046	2.5e-36	672	934
STKc_phototropin_lik	cd05574	8.8e-06	672	944
PKc_MKK3_6	cd06617	4.3e-07	672	955
STKc_MEKK2	cd06652	0.00072	672	935
STKc_MEKK3_like_1	cd06653	3.5e-05	672	934
STKc_CDK10	cd07845	1.5e-06	672	971
STKc_ERK1_2_like	cd07849	2.5e-06	672	991
STKc_Nek6	cd08228	3.5e-06	672	937
STKc_Nek7	cd08229	5.3e-09	672	937
STKc_Nek6_Nek7	cd08224	9e-09	672	937
STKc_PKA	cd05580	5.9e-06	673	958
STKc_DMPK_like	cd05597	0.00058	673	992
STKc_MAST	cd05609	2.1e-05	673	987
STKc_PRKX_like	cd05612	2.6e-05	673	957
STKc_MRCK_alpha	cd05623	0.00093	673	984
STKc_MRCK_beta	cd05624	0.00075	673	983
PKc_MAPKK	cd06605	1.9e-10	673	938
STKc_MST3_like	cd06609	1.9e-09	673	953
PKc_MEK	cd06615	3.5e-07	673	978
PKc_MKK5	cd06619	3.4e-05	673	960
PKc_MAPKK_Pek1_like	cd06621	8.2e-07	673	940
PKc_MAPKK_PBS2_like	cd06622	2.1e-07	673	981
STKc_NAK1_like	cd06917	6.8e-08	673	950
STKc_Pho85	cd07836	4e-06	673	955
STKc_CDK5	cd07839	5.9e-05	673	962
STKc_CDK1_euk	cd07861	6.8e-05	673	975
SPS1	COG0515	3.6e-22	673	1022
PTKc_RET	cd05045	3.9e-51	674	939
PKc_STE	cd05122	2.7e-14	674	925
STKc_GRK4_like	cd05605	6.6e-06	674	966
STKc_cPKC_alpha	cd05615	3e-05	674	986
STKc_GRK6	cd05630	0.00076	674	939
STKc_GRK4	cd05631	0.0002	674	939
STKc_GRK5	cd05632	0.0004	674	945
STKc_MAPKKK	cd06606	2.2e-18	674	928
STKc_Cdc7_like	cd06627	8.1e-17	674	928
STKc_MEKK3	cd06651	1.8e-06	674	936
STKc_CDK1_like	cd07835	4.6e-06	674	963
STKc_CDC2L1	cd07843	2.8e-06	674	962
STKc_NLK	cd07853	2.9e-07	674	1029
STKc_TDY_MAPK_plant	cd07859	4.4e-07	674	1010
STKc_BUR1	cd07866	1.9e-07	674	948
STKc_Nek11	cd08222	6.1e-10	674	936
STKc_Nek4	cd08223	7.7e-08	674	936
STKc_Nek5	cd08225	7e-08	674	932
PTKc_Axl_like	cd05035	9.3e-60	675	936
PTKc_Tyro3	cd05074	7.1e-54	675	936
PTKc_Axl	cd05075	6.9e-50	675	936
PTKc_Tyk2_rpt2	cd05080	5.9e-24	675	937
PTKc_Tie1	cd05089	1.1e-45	675	960
STKc_MSK_N	cd05583	7.8e-05	675	961
STKc_cPKC	cd05587	6e-05	675	989
STKc_PKN	cd05589	6e-05	675	992
STKc_MSK2_N	cd05614	0.00069	675	996
STKc_cPKC_beta	cd05616	0.00085	675	989
STKc_SLK_like	cd06611	1.3e-07	675	948
PKc_MAPKK_plant_like	cd06623	1.1e-11	675	934
STKc_CDK9_like	cd07840	7.5e-10	675	942
STKc_Nek3	cd08219	5.4e-10	675	932
STKc_CMGC	cd05118	1.2e-10	676	925
PTKc_Srm_Brk	cd05148	2e-78	676	935
STKc_Yank1	cd05578	5.1e-07	676	931
STKc_CRIK	cd05601	1.6e-05	676	970
STKc_myosinIII_like	cd06608	2.6e-07	676	936
STKc_MST1_2	cd06612	1e-10	676	928
STKc_YSK4	cd06631	6e-08	676	932
STKc_CDK_like	cd07829	9.8e-10	676	942
STKc_MAK_like	cd07830	3.5e-08	676	925
STKc_CCRK	cd07832	5.5e-08	676	925
STKc_MAPK	cd07834	6.5e-08	676	984
STKc_CdkB_plant	cd07837	5.1e-05	676	964
STKc_CDK7	cd07841	2.3e-07	676	943
STKc_CDK8_like	cd07842	0.00062	676	950
STKc_CDKL1_4	cd07847	3.5e-06	676	968
STKc_CDK2_3	cd07860	3.5e-05	676	963
STKc_CDK6	cd07862	0.00022	676	963
STKc_CDK4	cd07863	5.4e-05	676	962
STKc_MPK1	cd07857	1.3e-05	676	985
STKc_Nek	cd08215	1e-15	676	936
PK_STRAD	cd08216	9.3e-05	676	934
PK_STRAD_alpha	cd08227	0.0009	676	1033
STKc_Nek1	cd08218	5e-08	676	936
STKc_Nek10	cd08528	2.9e-05	676	934
STKc_CNK2-like	cd08530	1e-06	676	929
STKc_PDK1	cd05581	8.6e-08	677	925
STKc_OSR1_SPAK	cd06610	2.1e-09	677	925
STKc_FA2-like	cd08529	2.8e-09	677	941
PTKc_Fes	cd05084	1.3e-74	678	934
STKc_RSK_N	cd05582	8.8e-06	678	983
STKc_p70S6K	cd05584	3.3e-05	678	987
STKc_MEKK4	cd06626	1.8e-07	678	929
STKc_CDKL2_3	cd07846	6.1e-05	678	962
PTKc	cd00192	8.5e-136	679	933
PTK_Jak_rpt1	cd05037	7.3e-11	679	933
PTKc_Ack_like	cd05040	3.8e-75	679	934
PTKc_Fes_like	cd05041	4.7e-93	679	934
PTKc_c-ros	cd05044	2e-67	679	934
PTKc_Tie	cd05047	8.9e-52	679	937
PTKc_Met_Ron	cd05058	1.7e-65	679	938
PTKc_Syk_like	cd05060	4.9e-93	679	937
PTK_Jak1_rpt1	cd05077	4.1e-10	679	933
PTK_Jak2_Jak3_rpt1	cd05078	1.1e-12	679	933
PTKc_Fer	cd05085	3.6e-75	679	934
PTKc_Aatyk2	cd05086	2.2e-19	679	934
PTKc_Aatyk1_Aatyk3	cd05087	7.9e-19	679	934
PTKc_Syk	cd05116	6.6e-67	679	937
STKc_PKC	cd05570	3.2e-05	679	983
STKc_PKB	cd05571	9.5e-06	679	994
STKc_SGK	cd05575	0.00075	679	983
STKc_nPKC_epsilon	cd05591	0.00021	679	989
STKc_nPKC_theta_delt	cd05592	0.00025	679	990
STKc_PKB_alpha	cd05594	0.0002	679	1011
STKc_PKB_gamma	cd05593	0.00054	679	1008
STKc_SGK1	cd05602	0.00065	679	994
STKc_SGK2	cd05603	0.0002	679	993
STKc_nPKC_theta	cd05619	1e-05	679	989
STKc_MEKK3_like	cd06625	5.6e-09	679	934
STKc_MAPKKK_Byr2_lik	cd06628	6.8e-13	679	936
STKc_MEKK1	cd06630	3.6e-07	679	937
STKc_MEKK1_plant	cd06632	6.6e-10	679	929
STKc_MAPK4_6	cd07854	0.00029	679	990
STKc_Nek2	cd08217	2.7e-07	679	936
STKc_Nek8	cd08220	1.7e-07	679	936
STKc_Nek9	cd08221	7.6e-09	679	936
STKc_MAPKKK_Bck1_lik	cd06629	2.5e-10	680	926
STKc_CDKL	cd07833	0.00027	680	932
PKc	cd00180	3.9e-63	681	932
PTKc_Aatyk	cd05042	9.1e-15	681	934
PTKc_Zap-70	cd05115	1.3e-75	681	937
STKc_AGC	cd05123	9e-08	681	931
STKc_cGK_PKG	cd05572	6.2e-05	681	917
STKc_YPK1_like	cd05585	1.4e-05	681	979
STKc_Sck1_like	cd05586	9.1e-05	681	1032
STKc_GRK7	cd05607	0.00028	681	943
STKc_GRK1	cd05608	0.00098	681	962
STKc_MAST_like	cd05579	1.8e-06	681	934
STKc_MOK	cd07831	0.00021	681	962
STKc_CDK4_6_like	cd07838	0.00011	681	915
	cd00166	2.2e-26	964	1027
Ephrin_lbd	pfam01404	1.8e-126	60	233
fn3	pfam00041	2e-13	359	451
fn3	pfam00041	6.6e-16	470	552
Pkinase	pfam00069	9.6e-44	675	932
SAM_1	pfam00536	1.4e-30	963	1027
EPH_lbd	smart00615	2.1e-114	60	232
FN3	smart00060	2.3e-09	358	450
FN3	smart00060	4.6e-17	469	549
Pkinase_Tyr	pfam07714	8.9e-149	675	932
TyrKc	smart00219	1.7e-141	675	932
STYKc	smart00221	3.3e-59	675	992
S_TKc	smart00220	4.6e-47	685	936
SAM_2	pfam07647	5.3e-24	962	1027
SAM	smart00454	7.3e-24	962	1029

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs36050417	Polymorphism	p.ALA672THR	N/A
Swiss-Prot	VAR_042141	Polymorphism	p.ARG417GLN	N/A
Swiss-Prot	VAR_042148	Polymorphism	p.ASN1032SER	N/A
dbSNP	rs33932471	Polymorphism	p.ASN81THR	N/A
Swiss-Prot	VAR_042140	Polymorphism	p.GLU330GLN	N/A
Swiss-Prot	VAR_042142	Polymorphism	p.GLU503LYS	N/A
Swiss-Prot	VAR_042143	Polymorphism	p.GLY582GLU	N/A
Swiss-Prot	VAR_042147	Polymorphism	p.HIS959ARG	N/A
Swiss-Prot	VAR_042139	Polymorphism	p.SER235ALA	N/A
Swiss-Prot	VAR_042145	Polymorphism	p.SER673THR	N/A
Swiss-Prot	VAR_042146	Polymorphism	p.THR856ILE	N/A
Swiss-Prot	VAR_045912	Polymorphism	p.TYR506CYS	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258