Results for the protein: P29466

Results for the Protein: P29466

266321

834

CASP1

NCBI, UniProt

CASP1_HUMAN RecName: Full=Caspase-1; Short=CASP-1; AltName: Full=Interleukin-1 beta convertase; Short=IL-1BC; AltName: Full=Interleukin-1 beta-converting enzyme; Short=ICE; Short=IL-1 beta-converting enzyme; AltName: Full=p45; Contains: RecName: Full=Caspase-1 subunit p20; Contains: RecName: Full=Caspase-1 subunit p10; Flags: Precursor

			0 3 0 3 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

Default View: CARD - smart00114 CARD - pfam00619 CARD_CASP1-like - cd08325 CARD - cd01671 CARD_ASC_NALP1 - cd08330 CASc - cd00032 CASc - smart00115 Peptidase_C14 - pfam00656	Swiss-Prot Protein: P29466 Identical to: NP_150634 Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
CARD	cd01671	2.6e-18	6	87
CARD_ASC_NALP1	cd08330	0.00028	10	88
CASc	cd00032	3.9e-121	152	401
CARD	pfam00619	2.6e-32	3	90
Peptidase_C14	pfam00656	1.7e-84	163	400
CARD	smart00114	5.1e-09	1	89
CASc	smart00115	8.9e-136	153	402

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1042743	Polymorphism	p.ARG15HIS	N/A
dbSNP	rs61751523	Polymorphism	p.LYS319ARG	N/A
dbSNP	rs61738278	Polymorphism	p.SER81ARG	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258