Results for the protein: NP

Results for the Protein: NP_001161708

269847776

27

ABL2

NCBI

Abelson tyrosine-protein kinase 2 isoform f [Homo sapiens]

			0 1 0 1 0

Tips:

The Domains on the Default View are decided by the Domain's E-Value.

Clicking a check box will display or hide the correlated domain.

To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.

RefSeq Protein: NP_001161708

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_PDGFR_alpha	cd05105	3.3e-16	118	524
SH2	cd00173	3.9e-35	151	242
PTKc_CSF-1R	cd05106	1.7e-38	225	523
PTKc_Kit	cd05104	1.6e-30	229	522
STKc_ROCK2	cd05621	0.00013	232	591
STKc_ROCK1	cd05622	0.00062	232	594
PTKc_PDGFR_beta	cd05107	1.4e-13	233	523
STKc_myosinIIIB	cd06639	0.00011	234	524
STKc_myosinIIIA	cd06638	3.4e-06	242	520
STKc_TAO1	cd06635	8.9e-06	243	567
PTK_Tyk2_rpt1	cd05076	9.1e-07	244	519
STKc_PAK5	cd06658	0.001	244	552
STKc_PAK_I	cd06647	7.9e-07	246	539
STKc_TAO2	cd06634	4.9e-06	247	557
STKc_TAO3	cd06633	0.00034	247	556
STKc_JNK3	cd07874	0.00013	248	628
STKc_p38alpha_MAPK14	cd07877	2e-05	248	587
PTKc_PDGFR	cd05055	1.5e-31	250	522
STKc_p38	cd07851	1.5e-05	250	549
STKc_BUR1	cd07866	1.8e-07	250	518
STKc_p38gamma_MAPK12	cd07880	0.00024	250	587
STKc_p38beta_MAPK11	cd07878	0.00038	250	587
PTKc_FGFR2	cd05101	5.6e-61	251	529
STKc_TAO	cd06607	4.4e-06	251	567
STKc_MAP4K4_6	cd06636	0.00014	251	523
PTKc_FGFR1	cd05098	3.7e-58	252	529
PKc_MKK7	cd06618	1.7e-10	252	541
STKc_PAK1	cd06654	8.9e-07	252	541
STKc_SLK_like	cd06611	4.9e-10	253	533
STKc_PAK3	cd06656	1e-06	254	544
PTKc_FGFR	cd05053	4e-83	255	523
PTKc_FGFR4	cd05099	5.3e-64	255	543
PTKc_FGFR3	cd05100	2.3e-56	255	569
STKc_PAK4	cd06657	0.00047	256	537
STKc_PAK6	cd06659	2.7e-05	256	558
STKc_JNK	cd07850	2.8e-05	256	626
STKc_PAK	cd06614	2.6e-13	257	531
STKc_STK10_LOK	cd06644	1.6e-07	257	543
STKc_PAK_II	cd06648	2.4e-07	257	531
STKc_ASK	cd06624	7e-10	258	523
STKc_MST4	cd06640	4.7e-08	258	539
STKc_MST3	cd06641	4.5e-08	258	539
STKc_PAK2	cd06655	3.8e-07	258	540
STKc_MAPK15	cd07852	1.2e-05	258	535
STKc_CDK9	cd07865	5.1e-07	258	518
PTKc_EGFR_like	cd05057	3.9e-79	259	528
PTKc_VEGFR3	cd05102	3.6e-33	259	525
PTKc_VEGFR2	cd05103	3.9e-27	259	525
PTKc_VEGFR	cd05054	8.5e-29	259	525
PTKc_InsR_like	cd05032	2.1e-78	260	520
PTKc_Src_like	cd05034	4.9e-138	260	521
PTKc_ALK_LTK	cd05036	1.3e-72	260	520
PTKc_Csk_like	cd05039	5.4e-105	260	521
PTKc_Abl	cd05052	4.2e-210	260	522
PTKc_FAK	cd05056	2.9e-94	260	526
PTKc_InsR	cd05061	1.7e-58	260	533
PTKc_IGF-1R	cd05062	2.3e-62	260	520
PTKc_Lck_Blk	cd05067	9.2e-102	260	521
PTKc_Yes	cd05069	3.8e-94	260	522
PTKc_Fyn_Yrk	cd05070	1.6e-97	260	522
PTKc_Src	cd05071	2.7e-95	260	523
PTKc_Lyn	cd05072	1.7e-100	260	521
PTKc_Hck	cd05073	1.1e-97	260	521
PTKc_Csk	cd05082	4.9e-90	260	521
PTKc_Chk	cd05083	1.1e-85	260	521
PTKc_Frk_like	cd05068	4.5e-124	260	521
PTKc_Tie1	cd05089	1.2e-62	260	541
PTKc_Srm_Brk	cd05148	1.2e-105	260	521
STKc_TEY_MAPK_plant	cd07858	1.8e-05	260	587
STKc_CDK12	cd07864	5.9e-08	260	571
PTK_CCK4	cd05046	5.7e-48	261	520
PTKc_Ror	cd05048	1.5e-59	261	521
PTKc_Trk	cd05049	2.5e-67	261	520
PTKc_Musk	cd05050	1.6e-78	261	520
PTKc_DDR	cd05051	3e-58	261	520
PTKc_EphR_A10	cd05064	2.3e-56	261	522
PTKc_EphR_A2	cd05063	8.8e-68	261	522
PTKc_Ror1	cd05090	3.1e-53	261	521
PTKc_Ror2	cd05091	2.3e-42	261	521
PTKc_TrkA	cd05092	1.1e-57	261	520
PTKc_TrkB	cd05093	1.3e-52	261	530
PTKc_TrkC	cd05094	6e-37	261	530
PTKc_DDR1	cd05096	1.6e-47	261	520
PTKc_DDR2	cd05095	7.4e-59	261	520
PTKc_DDR_like	cd05097	5.9e-58	261	520
PKc_MAPKK_Byr1_like	cd06620	0.00011	261	532
STKc_TNIK	cd06637	6.9e-06	261	523
STKc_STK25-YSK1	cd06642	1.5e-09	261	539
STKc_MAP4K3	cd06645	1.7e-06	261	518
STKc_MAP4K5	cd06646	5.2e-06	261	517
PKc_MEK2	cd06649	3.1e-05	261	599
PKc_MEK1	cd06650	4.7e-05	261	603
STKc_PCTAIRE3	cd07871	1.2e-07	261	548
STKc_PCTAIRE2	cd07872	3e-07	261	562
STKc_PCTAIRE1	cd07873	1.9e-06	261	563
STKc_Nek8	cd08220	2.1e-06	261	519
PTKc_EphR	cd05033	3.9e-86	262	522
PTK_Ryk	cd05043	1.8e-43	262	526
PTKc_Jak_rpt2	cd05038	6.6e-69	262	522
PTKc_Tec_like	cd05059	2.3e-110	262	519
PTKc_EphR_B	cd05065	3.7e-66	262	522
PTKc_EphR_A	cd05066	1.8e-69	262	522
PTKc_Jak1_rpt2	cd05079	6.1e-42	262	522
PTKc_Tyk2_rpt2	cd05080	4.3e-33	262	523
PTKc_Jak2_Jak3_rpt2	cd05081	2.8e-52	262	522
PTKc_Tie2	cd05088	5.4e-56	262	542
PTKc_EGFR	cd05108	4.8e-60	262	573
PTKc_HER4	cd05110	6.2e-55	262	552
PTK_HER3	cd05111	2.2e-48	262	532
PTKc_Itk	cd05112	1.3e-92	262	519
PTKc_Btk_Bmx	cd05113	3.1e-98	262	519
PTKc_Tec_Rlk	cd05114	3.5e-93	262	519
PTKc_HER2	cd05109	3e-64	262	532
PKc_MKK4	cd06616	1.4e-09	262	539
STKc_SLK	cd06643	1.1e-07	262	536
STKc_PCTAIRE_like	cd07844	3.7e-08	262	548
STKc_CDK10	cd07845	4.2e-07	262	533
STKc_PFTAIRE1	cd07869	7.6e-05	262	556
STKc_MAP4K3_like	cd06613	1.1e-11	263	518
STKc_PFTAIRE2	cd07870	1.1e-07	263	548
STKc_MEKK2	cd06652	0.00017	264	523
STKc_MEKK3_like_1	cd06653	2.8e-06	264	520
STKc_ERK1_2_like	cd07849	8.8e-06	264	620
STKc_Nek6_Nek7	cd08224	4.1e-10	264	523
STKc_phototropin_lik	cd05574	1.7e-05	265	501
STKc_PKA	cd05580	2.1e-07	265	564
STKc_PDK1	cd05581	1e-11	265	518
STKc_DMPK_like	cd05597	0.00042	265	595
STKc_CRIK	cd05601	4.2e-05	265	556
STKc_MAST	cd05609	1.4e-05	265	581
STKc_PRKX_like	cd05612	2e-07	265	552
STKc_MRCK_beta	cd05624	0.00057	265	595
PKc_MAPKK	cd06605	3.6e-11	265	524
STKc_myosinIII_like	cd06608	2.2e-06	265	518
STKc_MST3_like	cd06609	4.4e-12	265	539
STKc_OSR1_SPAK	cd06610	7.4e-12	265	518
STKc_MST1_2	cd06612	7.5e-11	265	518
PKc_MEK	cd06615	6.1e-08	265	590
PKc_MKK5	cd06619	9.1e-06	265	543
PKc_MAPKK_Pek1_like	cd06621	4.3e-07	265	535
PKc_MAPKK_PBS2_like	cd06622	4.2e-09	265	578
PKc_MAPKK_plant_like	cd06623	1.5e-13	265	524
STKc_MEKK3_like	cd06625	1.7e-10	265	518
PKc_MKK3_6	cd06617	1.8e-09	265	536
STKc_CDKL1_4	cd07847	1.1e-08	265	518
STKc_CDKL5	cd07848	0.00094	265	571
STKc_CDK6	cd07862	0.00015	265	553
STKc_Nek7	cd08229	3.9e-11	265	523
STKc_Nek6	cd08228	9.4e-13	265	523
SPS1	COG0515	4.7e-33	265	697
PTKc_RET	cd05045	6.8e-66	266	525
PKc_STE	cd05122	3.5e-14	266	518
STKc_MSK_N	cd05583	6.5e-06	266	542
STKc_cPKC	cd05587	3.1e-07	266	593
STKc_MSK1_N	cd05613	0.0003	266	537
STKc_MSK2_N	cd05614	0.00067	266	587
STKc_cPKC_alpha	cd05615	1.7e-06	266	587
STKc_cPKC_beta	cd05616	3e-06	266	578
STKc_MAPKKK	cd06606	1.2e-19	266	518
STKc_Cdc7_like	cd06627	1.1e-14	266	518
STKc_MEKK3	cd06651	1.1e-06	266	521
STKc_CCRK	cd07832	4.3e-09	266	519
STKc_MAPK	cd07834	2.2e-07	266	563
STKc_Pho85	cd07836	1.9e-06	266	548
STKc_CdkB_plant	cd07837	3.6e-07	266	549
STKc_NLK	cd07853	0.0006	266	605
STKc_Sty1_Hog1	cd07856	2e-05	266	557
STKc_MPK1	cd07857	4.6e-05	266	543
STKc_TDY_MAPK_plant	cd07859	2.3e-05	266	595
STKc_CDK1_euk	cd07861	5.2e-07	266	548
STKc_CDK4	cd07863	4.6e-05	266	548
STKc_CDK2_3	cd07860	1.3e-06	266	548
STKc_Nek	cd08215	2.6e-15	266	523
STKc_Nek2	cd08217	3e-10	266	517
STKc_Nek1	cd08218	1.9e-06	266	520
STKc_Nek3	cd08219	2.1e-11	266	521
STKc_Nek4	cd08223	1.5e-09	266	519
STKc_Nek5	cd08225	8.9e-07	266	519
STKc_Nek11	cd08222	2.2e-11	266	520
STKc_Nek10	cd08528	3e-07	266	520
STKc_FA2-like	cd08529	7e-09	266	527
STKc_CNK2-like	cd08530	8.1e-08	266	518
PTKc_Axl_like	cd05035	2.6e-84	267	522
PTKc_Axl	cd05075	2.9e-70	267	522
PTKc_Tyro3	cd05074	2.6e-73	267	522
STKc_PKN	cd05589	1.4e-07	267	574
STKc_CDK1_like	cd07835	1.6e-07	267	548
STKc_GRK4_like	cd05605	6.8e-05	268	551
STKc_NAK1_like	cd06917	4.6e-12	268	536
STKc_CDK_like	cd07829	2.4e-13	268	518
STKc_MAK_like	cd07830	4.4e-13	268	520
STKc_CDK7	cd07841	2.4e-10	268	528
PK_STRAD	cd08216	0.00011	268	524
STKc_MAPKKK_Byr2_lik	cd06628	1.7e-12	269	519
STKc_MAPKKK_Bck1_lik	cd06629	8.8e-10	269	512
STKc_YSK4	cd06631	4.1e-10	269	518
STKc_CDKL2_3	cd07846	6.5e-09	269	518
STKc_RSK_N	cd05582	3.1e-06	270	596
STKc_p70S6K	cd05584	5.7e-06	270	594
STKc_MEKK4	cd06626	1e-09	270	512
STKc_CDK9_like	cd07840	9e-11	270	571
PTKc	cd00192	8.6e-144	271	519
PTK_Jak_rpt1	cd05037	9.6e-12	271	522
PTKc_Fes_like	cd05041	8.4e-96	271	520
PTKc_Aatyk	cd05042	1.2e-17	271	520
PTKc_Ack_like	cd05040	3.3e-80	271	520
PTKc_c-ros	cd05044	3.3e-71	271	520
PTKc_Tie	cd05047	1.3e-67	271	523
PTKc_Syk_like	cd05060	1.5e-97	271	523
PTKc_Met_Ron	cd05058	1.6e-71	271	524
PTK_Jak1_rpt1	cd05077	1.1e-09	271	519
PTK_Jak2_Jak3_rpt1	cd05078	7.8e-12	271	519
PTKc_Fes	cd05084	6.6e-77	271	520
PTKc_Fer	cd05085	7.1e-87	271	520
PTKc_Aatyk1_Aatyk3	cd05087	5.3e-33	271	520
PTKc_Syk	cd05116	1.4e-71	271	523
PTKc_Aatyk2	cd05086	1.8e-21	271	520
STKc_CMGC	cd05118	9.2e-12	271	518
STKc_PKC	cd05570	1.5e-08	271	521
STKc_PKB	cd05571	5.7e-08	271	583
STKc_SGK	cd05575	6.7e-06	271	584
STKc_aPKC	cd05588	1e-06	271	593
STKc_nPKC_eta	cd05590	1e-05	271	577
STKc_nPKC_epsilon	cd05591	6.8e-06	271	578
STKc_PKB_gamma	cd05593	8.5e-06	271	559
STKc_PKB_beta	cd05595	2.9e-06	271	587
STKc_PKB_alpha	cd05594	7e-08	271	588
STKc_SGK1	cd05602	0.00011	271	588
STKc_SGK2	cd05603	4.4e-07	271	578
STKc_SGK3	cd05604	0.00082	271	597
STKc_aPKC_zeta	cd05617	3.3e-05	271	572
STKc_aPKC_iota	cd05618	2.5e-05	271	572
STKc_nPKC_theta	cd05619	1e-07	271	576
STKc_nPKC_delta	cd05620	0.00072	271	587
STKc_nPKC_theta_delt	cd05592	2.2e-07	271	587
STKc_MEKK1	cd06630	8.4e-08	271	519
STKc_MOK	cd07831	5e-06	271	518
STKc_CDKL	cd07833	1.6e-09	271	518
STKc_CDK5	cd07839	6.7e-08	271	548
PTKc_Zap-70	cd05115	6.8e-67	272	523
STKc_CDK4_6_like	cd07838	4.1e-06	272	518
STKc_CDK8_like	cd07842	2.1e-06	272	518
PKc	cd00180	3.1e-67	273	518
STKc_AGC	cd05123	9.3e-12	273	521
STKc_cGK_PKG	cd05572	3.1e-09	273	526
STKc_ROCK_NDR_like	cd05573	4.4e-05	273	550
STKc_YPK1_like	cd05585	6.2e-06	273	591
STKc_Sck1_like	cd05586	2.2e-06	273	631
STKc_MAST_like	cd05579	5.2e-07	273	524
STKc_GRK1	cd05608	6.7e-05	273	556
STKc_MEKK1_plant	cd06632	7e-11	273	513
STKc_Nek9	cd08221	1.2e-07	273	520
STKc_Yank1	cd05578	5.8e-08	274	524
STKc_CDC2L1	cd07843	0.00012	276	518
SH3_1	pfam00018	8.9e-16	92	138
SH2	pfam00017	7.5e-37	152	227
Pkinase	pfam00069	7.3e-44	267	518
SH3	smart00326	6.4e-17	87	144
SH3_2	pfam07653	2.1e-06	90	143
SH2	smart00252	5.8e-35	150	233
Pkinase_Tyr	pfam07714	9.2e-153	267	518
STYKc	smart00221	1.4e-66	267	583
TyrKc	smart00219	4.5e-148	267	518
S_TKc	smart00220	2.3e-60	277	522
KIND	smart00750	0.00014	346	528
F_actin_bind	pfam08919	2.8e-122	999	1161
FABD	smart00808	2.7e-67	1042	1161

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs28913889	Polymorphism	p.VAL925MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258