Results for the protein: NP

Results for the Protein: NP_001161711

269847793

27

ABL2

NCBI

Abelson tyrosine-protein kinase 2 isoform i [Homo sapiens]

			0 2 0 2 0

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RefSeq Protein: NP_001161711

Default View:

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
PTKc_PDGFR_alpha	cd05105	3.3e-16	103	509
SH2	cd00173	3.9e-35	136	227
PTKc_CSF-1R	cd05106	1.7e-38	210	508
PTKc_Kit	cd05104	1.6e-30	214	507
STKc_ROCK2	cd05621	0.00013	217	576
STKc_ROCK1	cd05622	0.00062	217	579
PTKc_PDGFR_beta	cd05107	1.4e-13	218	508
STKc_myosinIIIB	cd06639	0.00011	219	509
STKc_myosinIIIA	cd06638	3.4e-06	227	505
STKc_TAO1	cd06635	8.9e-06	228	552
PTK_Tyk2_rpt1	cd05076	9.1e-07	229	504
STKc_PAK5	cd06658	0.001	229	537
STKc_PAK_I	cd06647	7.9e-07	231	524
STKc_TAO3	cd06633	0.00034	232	541
STKc_TAO2	cd06634	4.9e-06	232	542
STKc_JNK3	cd07874	0.00013	233	613
STKc_p38alpha_MAPK14	cd07877	2e-05	233	572
PTKc_PDGFR	cd05055	1.5e-31	235	507
STKc_p38	cd07851	1.5e-05	235	534
STKc_BUR1	cd07866	1.8e-07	235	503
STKc_p38beta_MAPK11	cd07878	0.00038	235	572
STKc_p38gamma_MAPK12	cd07880	0.00024	235	572
PTKc_FGFR2	cd05101	5.6e-61	236	514
STKc_TAO	cd06607	4.4e-06	236	552
STKc_MAP4K4_6	cd06636	0.00014	236	508
PTKc_FGFR1	cd05098	3.7e-58	237	514
PKc_MKK7	cd06618	1.7e-10	237	526
STKc_PAK1	cd06654	8.9e-07	237	526
STKc_SLK_like	cd06611	4.9e-10	238	518
STKc_PAK3	cd06656	1e-06	239	529
PTKc_FGFR	cd05053	4e-83	240	508
PTKc_FGFR4	cd05099	5.3e-64	240	528
PTKc_FGFR3	cd05100	2.3e-56	240	554
STKc_PAK4	cd06657	0.00047	241	522
STKc_PAK6	cd06659	2.7e-05	241	543
STKc_JNK	cd07850	2.8e-05	241	611
STKc_PAK	cd06614	2.6e-13	242	516
STKc_PAK_II	cd06648	2.4e-07	242	516
STKc_STK10_LOK	cd06644	1.6e-07	242	528
STKc_ASK	cd06624	7e-10	243	508
STKc_MST4	cd06640	4.7e-08	243	524
STKc_MST3	cd06641	4.5e-08	243	524
STKc_PAK2	cd06655	3.8e-07	243	525
STKc_CDK9	cd07865	5.1e-07	243	503
STKc_MAPK15	cd07852	1.2e-05	243	520
PTKc_VEGFR	cd05054	8.5e-29	244	510
PTKc_EGFR_like	cd05057	3.9e-79	244	513
PTKc_VEGFR3	cd05102	3.6e-33	244	510
PTKc_VEGFR2	cd05103	3.9e-27	244	510
PTKc_InsR_like	cd05032	2.1e-78	245	505
PTKc_Src_like	cd05034	4.9e-138	245	506
PTKc_ALK_LTK	cd05036	1.3e-72	245	505
PTKc_Csk_like	cd05039	5.4e-105	245	506
PTKc_Abl	cd05052	4.2e-210	245	507
PTKc_FAK	cd05056	2.9e-94	245	511
PTKc_InsR	cd05061	1.7e-58	245	518
PTKc_IGF-1R	cd05062	2.3e-62	245	505
PTKc_Lck_Blk	cd05067	9.2e-102	245	506
PTKc_Frk_like	cd05068	4.5e-124	245	506
PTKc_Yes	cd05069	3.8e-94	245	507
PTKc_Fyn_Yrk	cd05070	1.6e-97	245	507
PTKc_Src	cd05071	2.7e-95	245	508
PTKc_Lyn	cd05072	1.7e-100	245	506
PTKc_Hck	cd05073	1.1e-97	245	506
PTKc_Csk	cd05082	4.9e-90	245	506
PTKc_Chk	cd05083	1.1e-85	245	506
PTKc_Tie1	cd05089	1.2e-62	245	526
PTKc_Srm_Brk	cd05148	1.2e-105	245	506
STKc_TEY_MAPK_plant	cd07858	1.8e-05	245	572
STKc_CDK12	cd07864	5.9e-08	245	556
PTK_CCK4	cd05046	5.7e-48	246	505
PTKc_Ror	cd05048	1.5e-59	246	506
PTKc_Trk	cd05049	2.5e-67	246	505
PTKc_Musk	cd05050	1.6e-78	246	505
PTKc_DDR	cd05051	3e-58	246	505
PTKc_EphR_A2	cd05063	8.8e-68	246	507
PTKc_EphR_A10	cd05064	2.3e-56	246	507
PTKc_Ror1	cd05090	3.1e-53	246	506
PTKc_Ror2	cd05091	2.3e-42	246	506
PTKc_TrkA	cd05092	1.1e-57	246	505
PTKc_TrkB	cd05093	1.3e-52	246	515
PTKc_TrkC	cd05094	6e-37	246	515
PTKc_DDR2	cd05095	7.4e-59	246	505
PTKc_DDR_like	cd05097	5.9e-58	246	505
PTKc_DDR1	cd05096	1.6e-47	246	505
PKc_MAPKK_Byr1_like	cd06620	0.00011	246	517
STKc_TNIK	cd06637	6.9e-06	246	508
STKc_STK25-YSK1	cd06642	1.5e-09	246	524
STKc_MAP4K3	cd06645	1.7e-06	246	503
STKc_MAP4K5	cd06646	5.2e-06	246	502
PKc_MEK2	cd06649	3.1e-05	246	584
PKc_MEK1	cd06650	4.7e-05	246	588
STKc_PCTAIRE3	cd07871	1.2e-07	246	533
STKc_PCTAIRE1	cd07873	1.9e-06	246	548
STKc_PCTAIRE2	cd07872	3e-07	246	547
STKc_Nek8	cd08220	2.1e-06	246	504
PTKc_EphR	cd05033	3.9e-86	247	507
PTKc_Jak_rpt2	cd05038	6.6e-69	247	507
PTK_Ryk	cd05043	1.8e-43	247	511
PTKc_Tec_like	cd05059	2.3e-110	247	504
PTKc_EphR_B	cd05065	3.7e-66	247	507
PTKc_EphR_A	cd05066	1.8e-69	247	507
PTKc_Jak1_rpt2	cd05079	6.1e-42	247	507
PTKc_Tyk2_rpt2	cd05080	4.3e-33	247	508
PTKc_Jak2_Jak3_rpt2	cd05081	2.8e-52	247	507
PTKc_Tie2	cd05088	5.4e-56	247	527
PTKc_EGFR	cd05108	4.8e-60	247	558
PTKc_HER2	cd05109	3e-64	247	517
PTKc_HER4	cd05110	6.2e-55	247	537
PTKc_Itk	cd05112	1.3e-92	247	504
PTK_HER3	cd05111	2.2e-48	247	517
PTKc_Tec_Rlk	cd05114	3.5e-93	247	504
PTKc_Btk_Bmx	cd05113	3.1e-98	247	504
PKc_MKK4	cd06616	1.4e-09	247	524
STKc_SLK	cd06643	1.1e-07	247	521
STKc_PCTAIRE_like	cd07844	3.7e-08	247	533
STKc_CDK10	cd07845	4.2e-07	247	518
STKc_PFTAIRE1	cd07869	7.6e-05	247	541
STKc_MAP4K3_like	cd06613	1.1e-11	248	503
STKc_PFTAIRE2	cd07870	1.1e-07	248	533
STKc_MEKK2	cd06652	0.00017	249	508
STKc_MEKK3_like_1	cd06653	2.8e-06	249	505
STKc_ERK1_2_like	cd07849	8.8e-06	249	605
STKc_Nek6_Nek7	cd08224	4.1e-10	249	508
STKc_phototropin_lik	cd05574	1.7e-05	250	486
STKc_PKA	cd05580	2.1e-07	250	549
STKc_PDK1	cd05581	1e-11	250	503
STKc_CRIK	cd05601	4.2e-05	250	541
STKc_MAST	cd05609	1.4e-05	250	566
STKc_PRKX_like	cd05612	2e-07	250	537
STKc_MRCK_beta	cd05624	0.00057	250	580
STKc_DMPK_like	cd05597	0.00042	250	580
PKc_MAPKK	cd06605	3.6e-11	250	509
STKc_myosinIII_like	cd06608	2.2e-06	250	503
STKc_MST3_like	cd06609	4.4e-12	250	524
STKc_OSR1_SPAK	cd06610	7.4e-12	250	503
STKc_MST1_2	cd06612	7.5e-11	250	503
PKc_MEK	cd06615	6.1e-08	250	575
PKc_MKK3_6	cd06617	1.8e-09	250	521
PKc_MKK5	cd06619	9.1e-06	250	528
PKc_MAPKK_Pek1_like	cd06621	4.3e-07	250	520
PKc_MAPKK_PBS2_like	cd06622	4.2e-09	250	563
PKc_MAPKK_plant_like	cd06623	1.5e-13	250	509
STKc_MEKK3_like	cd06625	1.7e-10	250	503
STKc_CDKL1_4	cd07847	1.1e-08	250	503
STKc_CDKL5	cd07848	0.00094	250	556
STKc_CDK6	cd07862	0.00015	250	538
STKc_Nek6	cd08228	9.4e-13	250	508
STKc_Nek7	cd08229	3.9e-11	250	508
SPS1	COG0515	6.3e-34	250	669
PTKc_RET	cd05045	6.8e-66	251	510
PKc_STE	cd05122	3.5e-14	251	503
STKc_MSK_N	cd05583	6.5e-06	251	527
STKc_cPKC	cd05587	3.1e-07	251	578
STKc_MSK1_N	cd05613	0.0003	251	522
STKc_MSK2_N	cd05614	0.00067	251	572
STKc_cPKC_alpha	cd05615	1.7e-06	251	572
STKc_cPKC_beta	cd05616	3e-06	251	563
STKc_MAPKKK	cd06606	1.2e-19	251	503
STKc_Cdc7_like	cd06627	1.1e-14	251	503
STKc_MEKK3	cd06651	1.1e-06	251	506
STKc_CCRK	cd07832	4.3e-09	251	504
STKc_Pho85	cd07836	1.9e-06	251	533
STKc_CdkB_plant	cd07837	3.6e-07	251	534
STKc_MAPK	cd07834	2.2e-07	251	548
STKc_NLK	cd07853	0.0006	251	590
STKc_MPK1	cd07857	4.6e-05	251	528
STKc_TDY_MAPK_plant	cd07859	2.3e-05	251	580
STKc_CDK2_3	cd07860	1.3e-06	251	533
STKc_CDK1_euk	cd07861	5.2e-07	251	533
STKc_CDK4	cd07863	4.6e-05	251	533
STKc_Sty1_Hog1	cd07856	2e-05	251	542
STKc_Nek	cd08215	2.6e-15	251	508
STKc_Nek1	cd08218	1.9e-06	251	505
STKc_Nek3	cd08219	2.1e-11	251	506
STKc_Nek2	cd08217	3e-10	251	502
STKc_Nek11	cd08222	2.2e-11	251	505
STKc_Nek4	cd08223	1.5e-09	251	504
STKc_Nek5	cd08225	8.9e-07	251	504
STKc_Nek10	cd08528	3e-07	251	505
STKc_FA2-like	cd08529	7e-09	251	512
STKc_CNK2-like	cd08530	8.1e-08	251	503
PTKc_Axl_like	cd05035	2.6e-84	252	507
PTKc_Axl	cd05075	2.9e-70	252	507
PTKc_Tyro3	cd05074	2.6e-73	252	507
STKc_PKN	cd05589	1.4e-07	252	559
STKc_CDK1_like	cd07835	1.6e-07	252	533
STKc_GRK4_like	cd05605	6.8e-05	253	536
STKc_NAK1_like	cd06917	4.6e-12	253	521
STKc_CDK_like	cd07829	2.4e-13	253	503
STKc_MAK_like	cd07830	4.4e-13	253	505
STKc_CDK7	cd07841	2.4e-10	253	513
PK_STRAD	cd08216	0.00011	253	509
STKc_MAPKKK_Byr2_lik	cd06628	1.7e-12	254	504
STKc_MAPKKK_Bck1_lik	cd06629	8.8e-10	254	497
STKc_YSK4	cd06631	4.1e-10	254	503
STKc_CDKL2_3	cd07846	6.5e-09	254	503
STKc_RSK_N	cd05582	3.1e-06	255	581
STKc_p70S6K	cd05584	5.7e-06	255	579
STKc_MEKK4	cd06626	1e-09	255	497
STKc_CDK9_like	cd07840	9e-11	255	556
PTKc	cd00192	8.6e-144	256	504
PTK_Jak_rpt1	cd05037	9.6e-12	256	507
PTKc_Ack_like	cd05040	3.3e-80	256	505
PTKc_Fes_like	cd05041	8.4e-96	256	505
PTKc_Aatyk	cd05042	1.2e-17	256	505
PTKc_c-ros	cd05044	3.3e-71	256	505
PTKc_Tie	cd05047	1.3e-67	256	508
PTKc_Met_Ron	cd05058	1.6e-71	256	509
PTKc_Syk_like	cd05060	1.5e-97	256	508
PTK_Jak1_rpt1	cd05077	1.1e-09	256	504
PTK_Jak2_Jak3_rpt1	cd05078	7.8e-12	256	504
PTKc_Fes	cd05084	6.6e-77	256	505
PTKc_Fer	cd05085	7.1e-87	256	505
PTKc_Aatyk2	cd05086	1.8e-21	256	505
PTKc_Aatyk1_Aatyk3	cd05087	5.3e-33	256	505
PTKc_Syk	cd05116	1.4e-71	256	508
STKc_CMGC	cd05118	9.2e-12	256	503
STKc_PKB	cd05571	5.7e-08	256	568
STKc_PKC	cd05570	1.5e-08	256	506
STKc_SGK	cd05575	6.7e-06	256	569
STKc_aPKC	cd05588	1e-06	256	578
STKc_nPKC_eta	cd05590	1e-05	256	562
STKc_nPKC_epsilon	cd05591	6.8e-06	256	563
STKc_nPKC_theta_delt	cd05592	2.2e-07	256	572
STKc_PKB_gamma	cd05593	8.5e-06	256	544
STKc_PKB_alpha	cd05594	7e-08	256	573
STKc_PKB_beta	cd05595	2.9e-06	256	572
STKc_SGK1	cd05602	0.00011	256	573
STKc_SGK2	cd05603	4.4e-07	256	563
STKc_SGK3	cd05604	0.00082	256	582
STKc_aPKC_zeta	cd05617	3.3e-05	256	557
STKc_aPKC_iota	cd05618	2.5e-05	256	557
STKc_nPKC_delta	cd05620	0.00072	256	572
STKc_nPKC_theta	cd05619	1e-07	256	561
STKc_MEKK1	cd06630	8.4e-08	256	504
STKc_MOK	cd07831	5e-06	256	503
STKc_CDKL	cd07833	1.6e-09	256	503
STKc_CDK5	cd07839	6.7e-08	256	533
PTKc_Zap-70	cd05115	6.8e-67	257	508
STKc_CDK8_like	cd07842	2.1e-06	257	503
STKc_CDK4_6_like	cd07838	4.1e-06	257	503
PKc	cd00180	3.1e-67	258	503
STKc_AGC	cd05123	9.3e-12	258	506
STKc_cGK_PKG	cd05572	3.1e-09	258	511
STKc_ROCK_NDR_like	cd05573	4.4e-05	258	535
STKc_MAST_like	cd05579	5.2e-07	258	509
STKc_YPK1_like	cd05585	6.2e-06	258	576
STKc_GRK1	cd05608	6.7e-05	258	541
STKc_Sck1_like	cd05586	2.2e-06	258	616
STKc_MEKK1_plant	cd06632	7e-11	258	498
STKc_Nek9	cd08221	1.2e-07	258	505
STKc_Yank1	cd05578	5.8e-08	259	509
STKc_CDC2L1	cd07843	0.00012	261	503
SH3_1	pfam00018	8.9e-16	77	123
SH2	pfam00017	7.5e-37	137	212
Pkinase	pfam00069	7.3e-44	252	503
SH3	smart00326	6.4e-17	72	129
SH3_2	pfam07653	2.1e-06	75	128
SH2	smart00252	5.8e-35	135	218
Pkinase_Tyr	pfam07714	9.2e-153	252	503
TyrKc	smart00219	4.5e-148	252	503
STYKc	smart00221	1.4e-66	252	568
S_TKc	smart00220	2.3e-60	262	507
KIND	smart00750	0.00014	331	513
F_actin_bind	pfam08919	2.8e-122	881	1043
FABD	smart00808	2.7e-67	924	1043

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs1318056	Polymorphism	p.SER12THR	N/A
dbSNP	rs28913889	Polymorphism	p.VAL807MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258