Results for the protein: Q6DT37

Results for the Protein: Q6DT37

290457650

55561

CDC42BPG

NCBI, UniProt

MRCKG_HUMAN RecName: Full=Serine/threonine-protein kinase MRCK gamma; AltName: Full=CDC42-binding protein kinase gamma; AltName: Full=DMPK-like gamma; AltName: Full=Myotonic dystrophy kinase-related CDC42-binding kinase gamma; Short=MRCK gamma; Short=MRCKG; Short=Myotonic dystrophy protein kinase-like gamma; AltName: Full=Myotonic dystrophy protein kinase-like alpha

			0 7 0 2 5

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Swiss-Prot Protein: Q6DT37

Identical to: NP_059995

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
STKc_ROCK	cd05596	1.5e-175	27	400
STKc_ROCK1	cd05622	3e-144	27	401
STKc_JNK1	cd07875	0.0002	41	425
STKc_PAK3	cd06656	2.6e-09	43	365
STKc_PAK5	cd06658	3.1e-07	44	360
STKc_JNK2	cd07876	3.6e-05	44	423
STKc_TAO1	cd06635	3.3e-05	45	366
STKc_PAK4	cd06657	3e-07	46	359
STKc_PAK6	cd06659	3.8e-10	46	363
STKc_PAK1	cd06654	1.4e-08	46	363
STKc_myosinIIIB	cd06639	2e-09	47	338
STKc_PAK_I	cd06647	7.5e-08	48	361
STKc_JNK3	cd07874	9.2e-05	48	455
STKc_PAK_II	cd06648	3.9e-11	49	353
STKc_JNK	cd07850	1.7e-05	52	420
STKc_p38beta_MAPK11	cd07878	0.00052	53	395
STKc_MAP4K4_6	cd06636	1.4e-06	54	337
STKc_PAK2	cd06655	7e-09	54	364
STKc_CDK9	cd07865	2.6e-07	54	337
STKc_PAK	cd06614	3.1e-15	56	353
STKc_myosinIIIA	cd06638	7.4e-10	56	337
STKc_CDK10	cd07845	5.9e-06	56	354
STKc_p38	cd07851	7.1e-07	57	388
STKc_p38gamma_MAPK12	cd07880	1.7e-05	57	388
STKc_STK10_LOK	cd06644	1.6e-08	58	356
STKc_TAO	cd06607	2.8e-06	59	374
STKc_TAO2	cd06634	4.9e-06	59	375
PKc_MKK7	cd06618	2.7e-10	60	351
STKc_MAPK15	cd07852	2.6e-05	61	372
STKc_ASK	cd06624	1.6e-08	62	337
STKc_MAP4K5	cd06646	1.7e-07	63	336
PTKc_ALK_LTK	cd05036	1e-06	64	347
PTKc_Abl	cd05052	6.7e-06	64	341
PTKc_FAK	cd05056	1.5e-05	64	327
PTKc_Yes	cd05069	6.2e-05	64	340
PTKc_Fyn_Yrk	cd05070	9.6e-05	64	335
PTKc_Src	cd05071	3.5e-05	64	337
PTKc_Lyn	cd05072	4.3e-06	64	331
PTKc_Frk_like	cd05068	3.5e-05	64	340
PTKc_Hck	cd05073	1.9e-05	64	331
PTKc_Csk	cd05082	0.00018	64	340
STKc_myosinIII_like	cd06608	4.9e-12	64	337
STKc_TNIK	cd06637	3.8e-08	64	337
STKc_ERK5	cd07855	4.7e-05	64	359
STKc_TEY_MAPK_plant	cd07858	9e-06	64	380
PTKc_Trk	cd05049	1.3e-05	65	318
PTKc_EphR_A10	cd05064	7.8e-06	65	340
PTKc_Musk	cd05050	5e-05	65	334
STKc_MAP4K3	cd06645	4e-09	65	336
PKc_MEK2	cd06649	1.8e-07	65	379
PKc_MEK1	cd06650	2.5e-06	65	386
STKc_CDK12	cd07864	9.7e-08	65	337
PTKc_InsR_like	cd05032	6e-05	66	330
PTKc_Src_like	cd05034	5.5e-05	66	331
PTKc_EphR_B	cd05065	0.00031	66	337
PTKc_EphR_A	cd05066	0.0002	66	341
PTKc_Tec_like	cd05059	0.00021	66	316
PTKc_EphR	cd05033	0.00021	66	332
PTKc_Tyk2_rpt2	cd05080	0.00051	66	342
PTKc_Jak2_Jak3_rpt2	cd05081	0.00018	66	346
PTKc_Chk	cd05083	0.00063	66	338
PTKc_Tie2	cd05088	7.7e-05	66	342
PTK_HER3	cd05111	0.0003	66	337
PTKc_Itk	cd05112	0.00031	66	333
PTKc_Btk_Bmx	cd05113	4.2e-06	66	336
PTKc_Tec_Rlk	cd05114	2.4e-06	66	336
PKc_MKK4	cd06616	3.8e-08	66	357
PKc_MAPKK_Byr1_like	cd06620	2.1e-10	66	346
STKc_SLK	cd06643	7e-09	66	350
STKc_MAP4K3_like	cd06613	2.2e-13	67	336
STKc_PCTAIRE_like	cd07844	9.5e-07	67	356
STKc_BUR1	cd07866	4.6e-07	67	337
STKc_PFTAIRE1	cd07869	0.00099	67	346
STKc_PFTAIRE2	cd07870	1.2e-05	67	353
STKc_PCTAIRE3	cd07871	2.8e-05	67	353
STKc_PCTAIRE1	cd07873	4.7e-05	67	350
STKc_PCTAIRE2	cd07872	0.00011	67	357
PTKc_Srm_Brk	cd05148	0.0005	68	331
STKc_SLK_like	cd06611	3.6e-08	68	318
STKc_MST4	cd06640	7.2e-08	68	360
STKc_MST3	cd06641	2.5e-07	68	335
STKc_MEKK2	cd06652	1.1e-06	68	338
STKc_MEKK3_like_1	cd06653	1.7e-08	68	337
STKc_STK25-YSK1	cd06642	6.4e-08	68	335
STKc_ERK1_2_like	cd07849	5.3e-05	68	387
STKc_Nek6_Nek7	cd08224	3.3e-09	68	337
PTKc_Tie1	cd05089	5.3e-05	69	341
STKc_phototropin_lik	cd05574	1.2e-57	69	361
STKc_ROCK_NDR_like	cd05573	2.1e-188	69	399
STKc_PKA	cd05580	4.1e-68	69	368
STKc_PDK1	cd05581	8.3e-64	69	337
STKc_LATS	cd05598	2.4e-84	69	402
STKc_Sid2p_Dbf2p	cd05600	2e-52	69	400
STKc_CRIK	cd05601	1.7e-152	69	399
STKc_DMPK_like	cd05597	2.4e-243	69	399
STKc_MAST	cd05609	2.6e-66	69	366
STKc_PRKX_like	cd05612	1.4e-60	69	369
STKc_MASTL	cd05610	0.00022	69	724
STKc_MRCK_alpha	cd05623	8.7e-237	69	400
STKc_MRCK_beta	cd05624	2.9e-230	69	399
STKc_LATS2	cd05626	8.3e-72	69	402
STKc_NDR2	cd05627	1.1e-92	69	423
STKc_NDR_like_fungal	cd05629	3.1e-98	69	402
STKc_NDR_like	cd05599	1.6e-108	69	402
STKc_NDR1	cd05628	1.9e-93	69	402
STKc_MST3_like	cd06609	7.6e-13	69	324
STKc_OSR1_SPAK	cd06610	6.9e-14	69	337
PKc_MEK	cd06615	4.5e-12	69	357
PKc_MKK3_6	cd06617	1.8e-09	69	355
PKc_MKK5	cd06619	0.00018	69	357
PKc_MAPKK_Pek1_like	cd06621	1.1e-08	69	342
PKc_MAPKK_PBS2_like	cd06622	6e-10	69	375
PKc_MAPKK_plant_like	cd06623	1.2e-16	69	342
STKc_MST1_2	cd06612	3.9e-14	69	312
PKc_MAPKK	cd06605	2.4e-13	69	342
STKc_NAK1_like	cd06917	1.7e-10	69	336
STKc_CDKL	cd07833	1.5e-09	69	337
STKc_CdkB_plant	cd07837	1.8e-10	69	338
STKc_CDC2L1	cd07843	5.5e-07	69	337
STKc_CDKL2_3	cd07846	3.8e-08	69	337
STKc_CDKL1_4	cd07847	7e-10	69	365
STKc_CDKL5	cd07848	9.4e-07	69	337
STKc_CDK6	cd07862	0.00014	69	353
STKc_Nek6	cd08228	1.1e-07	69	340
STKc_Nek7	cd08229	2.2e-09	69	337
SPS1	COG0515	6.5e-54	69	476
PTKc_Jak_rpt2	cd05038	8.7e-06	70	324
PKc_STE	cd05122	4.7e-30	70	336
STKc_Yank1	cd05578	4.5e-68	70	337
STKc_MSK_N	cd05583	6.9e-67	70	354
STKc_cPKC	cd05587	9.3e-58	70	400
STKc_GRK4_like	cd05605	4.7e-36	70	356
STKc_MSK1_N	cd05613	8.5e-54	70	354
STKc_MSK2_N	cd05614	1.4e-63	70	396
STKc_cPKC_alpha	cd05615	1.1e-43	70	400
STKc_cPKC_beta	cd05616	7.8e-49	70	400
STKc_GRK6	cd05630	1.2e-32	70	356
STKc_GRK4	cd05631	7.1e-29	70	356
STKc_GRK5	cd05632	2.2e-27	70	356
STKc_MAPKKK	cd06606	1.7e-40	70	337
STKc_Cdc7_like	cd06627	1.1e-16	70	337
STKc_MEKK3	cd06651	2.2e-09	70	339
STKc_CCRK	cd07832	1.5e-14	70	338
STKc_MAPK	cd07834	3.1e-07	70	374
STKc_Pho85	cd07836	2.1e-05	70	353
STKc_CDK5	cd07839	1.1e-06	70	337
STKc_CDK7	cd07841	1.5e-09	70	324
STKc_CDK8_like	cd07842	7.9e-05	70	337
STKc_NLK	cd07853	5.2e-05	70	441
STKc_MPK1	cd07857	1.3e-05	70	371
STKc_CDK2_3	cd07860	3.2e-06	70	337
STKc_CDK4	cd07863	5.4e-06	70	337
STKc_CDC2L6	cd07867	0.001	70	391
STKc_CDK1_euk	cd07861	1e-06	70	353
STKc_TDY_MAPK_plant	cd07859	1.1e-06	70	375
STKc_Nek	cd08215	2.6e-19	70	337
STKc_Nek2	cd08217	1.9e-15	70	337
STKc_Nek1	cd08218	2.2e-19	70	337
STKc_Nek3	cd08219	6.4e-25	70	328
STKc_Nek8	cd08220	1.5e-09	70	337
STKc_Nek9	cd08221	3.9e-09	70	317
STKc_Nek11	cd08222	8.1e-07	70	337
STKc_Nek4	cd08223	3.7e-13	70	337
STKc_Nek5	cd08225	8.9e-19	70	337
STKc_CNK2-like	cd08530	2.9e-11	70	337
STKc_FA2-like	cd08529	3e-14	70	328
STKc_Nek10	cd08528	3.7e-07	70	310
STKc_CMGC	cd05118	5.5e-13	71	337
STKc_PKN	cd05589	7.5e-57	71	399
STKc_LATS1	cd05625	2.7e-62	71	402
STKc_MAPKKK_Bck1_lik	cd06629	6.8e-08	71	337
STKc_CDK_like	cd07829	2.9e-13	71	337
STKc_MAK_like	cd07830	4.5e-10	71	337
STKc_CDK1_like	cd07835	6.6e-07	71	356
STKc_CDK4_6_like	cd07838	1.1e-08	71	337
STKc_CDK9_like	cd07840	1.2e-09	71	337
STKc_MOK	cd07831	7.7e-10	71	337
STKc_Sty1_Hog1	cd07856	5.7e-05	71	377
STKc_MAPKKK_Byr2_lik	cd06628	7.3e-08	72	337
PK_STRAD	cd08216	2.1e-05	72	355
PK_STRAD_alpha	cd08227	8.8e-06	72	439
STKc_RSK_N	cd05582	1.5e-58	74	399
STKc_p70S6K	cd05584	4.1e-61	74	401
STKc_Rim15_like	cd05611	6.5e-21	74	343
STKc_MEKK4	cd06626	8.1e-12	74	337
PTKc	cd00192	1.6e-09	75	336
PTKc_Fes_like	cd05041	1e-07	75	310
PTKc_c-ros	cd05044	3e-05	75	334
PTKc_Fes	cd05084	9.6e-05	75	346
PTKc_Fer	cd05085	0.00028	75	313
STKc_PKC	cd05570	8e-47	75	399
STKc_PKB	cd05571	2.2e-54	75	401
STKc_SGK	cd05575	4.7e-67	75	399
STKc_aPKC	cd05588	2.5e-46	75	400
STKc_nPKC_eta	cd05590	1.1e-58	75	400
STKc_nPKC_epsilon	cd05591	1.4e-53	75	400
STKc_PKB_gamma	cd05593	8.7e-33	75	404
STKc_PKB_alpha	cd05594	2.8e-35	75	402
STKc_PKB_beta	cd05595	3e-44	75	401
STKc_nPKC_theta_delt	cd05592	2.2e-58	75	401
STKc_SGK2	cd05603	7.2e-54	75	400
STKc_SGK3	cd05604	1.3e-49	75	401
STKc_aPKC_zeta	cd05617	1e-36	75	400
STKc_aPKC_iota	cd05618	1.8e-35	75	400
STKc_nPKC_theta	cd05619	8.7e-46	75	401
STKc_nPKC_delta	cd05620	2.7e-39	75	401
STKc_SGK1	cd05602	3.8e-50	75	401
STKc_MEKK3_like	cd06625	3.7e-14	75	337
STKc_MEKK1	cd06630	1e-08	75	338
STKc_YSK4	cd06631	1.4e-09	75	337
STKc_MEKK1_plant	cd06632	1.2e-11	75	337
STKc_beta_ARK	cd05606	7.7e-35	76	355
STKc_GRK3	cd05633	2.1e-25	76	356
PKc	cd00180	1.3e-62	77	335
STKc_AGC	cd05123	4e-108	77	337
PTKc_Zap-70	cd05115	0.00012	77	337
STKc_GRK	cd05577	6e-35	77	355
STKc_cGK_PKG	cd05572	2.7e-55	77	344
STKc_Sck1_like	cd05586	2.1e-51	77	442
STKc_YPK1_like	cd05585	4.9e-68	77	398
STKc_GRK7	cd05607	1.5e-37	77	355
STKc_GRK1	cd05608	4.3e-35	77	355
STKc_MAST_like	cd05579	8.6e-70	77	342
C1	cd00029	2.4e-10	879	927
PH_MRCK	cd01243	1.2e-48	947	1068
PH	cd00821	6.2e-07	950	1064
PH-like	cd00900	0.0003	950	1064
Pkinase	pfam00069	1.6e-62	71	337
Pkinase_C	pfam00433	2.3e-11	355	402
C1_1	pfam00130	2.1e-10	879	931
PH	pfam00169	2.5e-07	948	1066
CNH	pfam00780	1.8e-68	1097	1363
Pkinase_Tyr	pfam07714	3.8e-12	71	315
TyrKc	smart00219	1.2e-10	71	315
STYKc	smart00221	1.7e-80	71	337
S_TKc	smart00220	1.6e-86	81	337
S_TK_X	smart00133	1.1e-12	338	400
DMPK_coil	pfam08826	1.8e-23	744	801
C1	smart00109	2.2e-09	879	927
PH	smart00233	2.6e-10	948	1066
CNH	smart00036	2.2e-07	1092	1372

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_040843	Polymorphism	p.ALA537ASP	N/A
dbSNP	rs11231887	Polymorphism	p.ALA1048THR	N/A
dbSNP	rs55975541	Polymorphism	p.ARG1237TRP	N/A
Swiss-Prot	VAR_057105	Polymorphism	p.GLN1135ARG	N/A
Swiss-Prot	VAR_040840	Polymorphism	p.PRO168LEU	N/A
Swiss-Prot	VAR_040841	Polymorphism	p.SER280PHE	N/A
Swiss-Prot	VAR_040842	Polymorphism	p.THR362PRO	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258