Results for the protein: O15197

Results for the Protein: O15197

294862532

2051

EPHB6

NCBI, UniProt

EPHB6_HUMAN RecName: Full=Ephrin type-B receptor 6; AltName: Full=HEP; AltName: Full=Tyrosine-protein kinase-defective receptor EPH-6; Flags: Precursor

			0 18 0 0 18

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Swiss-Prot Protein: O15197

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
FN3	cd00063	1e-17	488	579
PTKc_VEGFR	cd05054	3.5e-05	554	922
PTKc_PDGFR_alpha	cd05105	9.4e-08	558	921
PTKc_PDGFR_beta	cd05107	3.3e-06	558	920
PTKc_Kit	cd05104	3.1e-08	558	919
PTKc_PDGFR	cd05055	6.7e-11	628	919
PTKc_CSF-1R	cd05106	3.4e-05	637	920
STKc_TAO1	cd06635	0.00065	648	956
PTKc_FGFR1	cd05098	9e-11	649	926
STKc_PAK6	cd06659	3.6e-06	649	954
PTKc_FGFR2	cd05101	1e-11	650	930
STKc_PAK	cd06614	1.8e-08	651	928
STKc_PAK_II	cd06648	1.2e-06	651	929
STKc_TAO2	cd06634	0.00026	653	955
PTKc_FGFR4	cd05099	5.1e-16	654	938
PTKc_FGFR3	cd05100	1e-08	654	957
PTK_Tyk2_rpt1	cd05076	1.9e-05	655	916
STKc_TAO	cd06607	0.00011	656	942
PKc_MKK7	cd06618	0.00011	657	942
PTKc_FGFR	cd05053	6.3e-14	658	920
STKc_STK10_LOK	cd06644	0.00017	658	936
PTKc_DDR	cd05051	1.8e-17	660	917
STKc_MAP4K3	cd06645	0.00085	660	915
STKc_ASK	cd06624	2.1e-05	661	919
PTKc_EGFR_like	cd05057	5.9e-39	662	926
PTKc_VEGFR3	cd05102	4.4e-09	662	922
PTKc_VEGFR2	cd05103	1.2e-08	662	922
PTKc_EGFR	cd05108	1.4e-24	662	958
PTKc_HER4	cd05110	8.6e-18	662	944
PTK_HER3	cd05111	6.8e-27	662	929
PTKc_HER2	cd05109	8.2e-26	662	929
STKc_CDK12	cd07864	4.2e-05	662	944
PTKc_ALK_LTK	cd05036	1.9e-31	663	917
PTKc_FAK	cd05056	1.8e-42	663	923
PTKc_Csk_like	cd05039	2.5e-35	664	918
PTK_CCK4	cd05046	4e-16	664	917
PTKc_Ror	cd05048	7.5e-29	664	918
PTKc_Src_like	cd05034	1.9e-43	664	918
PTKc_Trk	cd05049	2.3e-31	664	927
PTKc_Musk	cd05050	3.5e-38	664	917
PTKc_Abl	cd05052	3.2e-52	664	919
PTKc_InsR	cd05061	3.1e-25	664	929
PTKc_IGF-1R	cd05062	4e-24	664	917
PTKc_EphR_A2	cd05063	4e-111	664	919
PTKc_EphR_A10	cd05064	1.6e-112	664	919
PTKc_Lck_Blk	cd05067	2.2e-41	664	918
PTKc_Fyn_Yrk	cd05070	8.5e-44	664	918
PTKc_Yes	cd05069	1.1e-38	664	918
PTKc_Lyn	cd05072	7.6e-41	664	918
PTKc_Src	cd05071	7.2e-43	664	920
PTKc_Hck	cd05073	2e-44	664	918
PTKc_Csk	cd05082	4.9e-38	664	918
PTKc_Frk_like	cd05068	3.6e-59	664	918
PTKc_InsR_like	cd05032	2.8e-24	664	917
PTKc_Ror1	cd05090	4.3e-35	664	918
PTKc_Ror2	cd05091	3.6e-31	664	918
PTKc_TrkA	cd05092	7.3e-31	664	927
PTKc_TrkB	cd05093	4.8e-17	664	926
PTKc_DDR2	cd05095	3.9e-26	664	917
PTKc_DDR1	cd05096	1.3e-20	664	917
PTKc_DDR_like	cd05097	2.9e-31	664	917
PKc_MAPKK_Byr1_like	cd06620	0.00021	664	929
STKc_TNIK	cd06637	0.00035	664	916
PTKc_EphR	cd05033	6.9e-134	665	919
PTKc_Jak_rpt2	cd05038	7.9e-15	665	919
PTK_Ryk	cd05043	1.2e-19	665	919
PTKc_Tec_like	cd05059	2.2e-36	665	916
PTKc_EphR_B	cd05065	2.2e-133	665	919
PTKc_EphR_A	cd05066	5.8e-120	665	919
PTKc_Jak1_rpt2	cd05079	2.6e-18	665	919
PTKc_Jak2_Jak3_rpt2	cd05081	1.4e-12	665	919
PTKc_Chk	cd05083	7.3e-49	665	918
PTKc_Btk_Bmx	cd05113	2.9e-44	665	916
PTKc_Itk	cd05112	7.7e-47	665	916
PTKc_Tec_Rlk	cd05114	8e-49	665	916
PTKc_Tie2	cd05088	2.7e-18	665	931
STKc_SLK_like	cd06611	3.8e-06	665	928
STKc_SLK	cd06643	0.00034	665	931
STKc_PCTAIRE_like	cd07844	0.00074	665	950
STKc_myosinIII_like	cd06608	3.1e-05	666	916
STKc_MST4	cd06640	3e-06	666	936
STKc_MST3	cd06641	2.5e-05	666	936
STKc_STK25-YSK1	cd06642	1.1e-05	666	936
STKc_OSR1_SPAK	cd06610	5.1e-07	667	915
STKc_MAP4K3_like	cd06613	1.5e-07	667	916
STKc_MEKK3_like	cd06625	2.4e-06	667	917
STKc_MEKK3	cd06651	9.5e-05	667	918
STKc_CdkB_plant	cd07837	7.2e-05	667	951
STKc_CDK10	cd07845	0.0003	667	948
STKc_CDKL2_3	cd07846	0.00034	667	948
STKc_PRKX_like	cd05612	1.9e-05	668	938
STKc_MST3_like	cd06609	7.8e-07	668	936
PKc_MAPKK_plant_like	cd06623	6.5e-08	668	924
STKc_Cdc7_like	cd06627	7.2e-12	668	912
STKc_MAPKKK	cd06606	3e-12	668	912
STKc_MAPKKK_Byr2_lik	cd06628	2.4e-06	668	916
STKc_NAK1_like	cd06917	6e-05	668	928
STKc_CDK5	cd07839	0.00052	668	944
STKc_CDK7	cd07841	0.00026	668	953
STKc_CDK4	cd07863	0.00066	668	944
STKc_Nek9	cd08221	0.00037	668	917
STKc_Nek11	cd08222	0.00029	668	916
STKc_Nek7	cd08229	0.00026	668	920
STKc_Nek4	cd08223	0.0004	668	916
SPS1	COG0515	1.2e-05	668	1018
PTKc_RET	cd05045	1.1e-11	669	922
PTKc_Tyk2_rpt2	cd05080	1.7e-10	669	920
PTKc_TrkC	cd05094	9.7e-10	669	926
STKc_CMGC	cd05118	1.5e-05	669	944
PKc_STE	cd05122	1.8e-10	669	915
STKc_CDK_like	cd07829	3.4e-06	669	944
STKc_CDK9_like	cd07840	0.00025	669	944
STKc_Nek3	cd08219	2.1e-05	669	917
PTKc_Axl_like	cd05035	2.1e-23	670	919
PTKc_Tyro3	cd05074	5.7e-30	670	919
PTKc_Axl	cd05075	6e-21	670	919
PTKc_Tie1	cd05089	6.4e-20	670	930
STKc_PKN	cd05589	0.00045	670	975
PKc_MAPKK	cd06605	9.5e-06	670	921
PKc_MAPKK_PBS2_like	cd06622	0.00024	670	968
PTKc_Srm_Brk	cd05148	1.7e-28	671	918
STKc_PDK1	cd05581	1.6e-05	671	908
STKc_MST1_2	cd06612	2.7e-05	671	912
STKc_CCRK	cd07832	0.00031	671	909
STKc_Nek	cd08215	1.8e-07	671	916
STKc_Nek2	cd08217	0.00068	671	919
STKc_RSK_N	cd05582	0.00082	673	972
PTKc	cd00192	1.1e-73	674	916
PTK_Jak_rpt1	cd05037	9.3e-09	674	916
PTKc_Ack_like	cd05040	1.5e-27	674	917
PTKc_Fes_like	cd05041	2.3e-39	674	917
PTKc_Aatyk	cd05042	5.4e-12	674	914
PTKc_c-ros	cd05044	4.2e-32	674	917
PTKc_Tie	cd05047	8.9e-26	674	920
PTKc_Syk_like	cd05060	8.2e-33	674	920
PTKc_Met_Ron	cd05058	4.5e-38	674	921
PTK_Jak1_rpt1	cd05077	2.1e-08	674	916
PTK_Jak2_Jak3_rpt1	cd05078	2.2e-09	674	916
PTKc_Fes	cd05084	6.3e-47	674	917
PTKc_Fer	cd05085	1.4e-41	674	917
PTKc_Aatyk2	cd05086	6.7e-09	674	914
PTKc_Aatyk1_Aatyk3	cd05087	8.9e-08	674	917
PTKc_Syk	cd05116	3.9e-33	674	920
STKc_SGK	cd05575	0.00099	674	975
STKc_nPKC_epsilon	cd05591	0.00061	674	976
STKc_nPKC_theta_delt	cd05592	0.00063	674	977
STKc_SGK2	cd05603	0.00045	674	997
STKc_nPKC_theta	cd05619	0.00054	674	974
STKc_MAPKKK_Bck1_lik	cd06629	8.1e-05	674	909
STKc_YSK4	cd06631	0.00014	674	916
STKc_MEKK1_plant	cd06632	5.8e-07	674	912
STKc_MEKK1	cd06630	0.0002	674	916
PKc	cd00180	2.7e-30	676	915
STKc_AGC	cd05123	7.2e-07	676	918
PTKc_Zap-70	cd05115	7.6e-37	676	920
STKc_YPK1_like	cd05585	0.00029	676	982
PK_STRAD	cd08216	0.00024	700	927
	cd00166	3.8e-18	947	1010
Ephrin_lbd	pfam01404	2.1e-108	33	232
fn3	pfam00041	0.00028	371	470
fn3	pfam00041	5.2e-16	489	572
Pkinase	pfam00069	7.2e-19	670	915
SAM_1	pfam00536	3.6e-12	952	1010
EPH_lbd	smart00615	6e-99	33	231
FN3	smart00060	9.3e-15	488	569
Pkinase_Tyr	pfam07714	5.1e-80	670	915
TyrKc	smart00219	5.4e-70	670	915
STYKc	smart00221	9.6e-28	670	917
S_TKc	smart00220	5e-12	680	919
SAM_2	pfam07647	6.4e-21	945	1010
SAM	smart00454	8.2e-18	945	1012

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
Swiss-Prot	VAR_036092	Polymorphism	p.ALA603PRO	N/A
Swiss-Prot	VAR_042191	Polymorphism	p.ALA221VAL	N/A
Swiss-Prot	VAR_042195	Polymorphism	p.ALA662VAL	N/A
Swiss-Prot	VAR_042193	Polymorphism	p.ARG309GLN	N/A
Swiss-Prot	VAR_019142	Polymorphism	p.ARG499GLN	N/A
Swiss-Prot	VAR_036093	Polymorphism	p.ARG719GLN	N/A
Swiss-Prot	VAR_042197	Polymorphism	p.ARG813HIS	N/A
Swiss-Prot	VAR_036091	Polymorphism	p.ASP360ASN	N/A
Swiss-Prot	VAR_036094	Polymorphism	p.ASP930GLY	N/A
Swiss-Prot	VAR_042198	Polymorphism	p.GLU875LYS	N/A
Swiss-Prot	VAR_019139	Polymorphism	p.GLY122SER	N/A
Swiss-Prot	VAR_042199	Polymorphism	p.ILE993VAL	N/A
Swiss-Prot	VAR_019140	Polymorphism	p.PRO282ARG	N/A
Swiss-Prot	VAR_042192	Polymorphism	p.PRO282HIS	N/A
Swiss-Prot	VAR_042196	Polymorphism	p.PRO743SER	N/A
Swiss-Prot	VAR_019141	Polymorphism	p.SER324ALA	N/A
Swiss-Prot	VAR_042194	Polymorphism	p.SER332LEU	N/A
Swiss-Prot	VAR_042190	Polymorphism	p.SER170THR	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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