Results for the protein: P43146

Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Ig1_Neogenin	cd05722	2e-66	41	136
Ig1_Contactin	cd04967	3.1e-05	42	133
Ig2_Robo	cd05724	4.3e-08	44	136
Ig	cd00096	9.5e-09	57	133
Ig3_Contactin_like	cd04968	4.5e-06	139	233
Ig3_Contactin-1	cd05851	0.00016	139	231
Ig1_Robo	cd07693	2e-05	139	228
Ig1_Neogenin	cd05722	4.3e-05	141	230
Ig4_Contactin-2-like	cd05728	5.7e-05	141	230
Ig2_Robo	cd05724	1.3e-07	144	230
Ig2_FGFRL1-like	cd05856	0.00029	146	228
Ig2_FGFR_like	cd05729	2.7e-05	147	228
Ig3_Peroxidasin	cd05745	2.7e-09	153	228
Ig5_Contactin_like	cd04969	4.7e-05	154	233
Ig4_L1-NrCAM_like	cd04978	1.3e-06	154	217
Ig4_Robo	cd05726	6.2e-06	154	237
Ig_Perlecan_D2_like	cd05743	0.0008	154	230
Ig_2	cd05764	3.7e-07	154	230
Ig_3	cd05765	9.3e-08	154	228
Ig2_RPTP_IIa_LAR_lik	cd05738	0.00014	155	231
Ig4_Neogenin	cd05723	0.00037	156	230
Ig	cd00096	1.4e-11	157	229
Ig3_Robo	cd05725	2.7e-05	157	230
Ig6_L1-CAM_like	cd05733	0.00037	157	229
Ig4_Peroxidasin	cd05746	0.00062	157	232
Ig_1	cd05763	4.9e-07	157	231
Ig3_NCAM-1_like	cd05730	0.00012	239	330
Ig1_Neogenin	cd05722	4.5e-07	241	327
Ig4_Contactin-2-like	cd05728	3.3e-07	241	327
Ig1_Contactin	cd04967	4.7e-05	242	326
Ig1_Contactin-1	cd05849	0.00045	242	329
Ig3_Contactin_like	cd04968	0.00077	243	328
Ig_Semaphorin_C	cd04979	0.00069	244	330
Ig2_Robo	cd05724	2.7e-11	244	327
Ig2_FGFR_like	cd05729	0.00015	245	327
Ig2_IL1R_like	cd05757	3.9e-05	245	329
Ig_C5_MyBP-C	cd05894	0.00013	245	329
Ig2_FGFRL1-like	cd05856	0.0005	247	327
Ig_Myomesin_like_C	cd05737	0.00016	249	329
Ig3_Peroxidasin	cd05745	0.00014	253	327
Ig5_Contactin_like	cd04969	4.4e-06	254	327
Ig4_L1-NrCAM_like	cd04978	1.3e-05	254	328
Ig4_NrCAM	cd05868	0.00019	254	328
Ig4_Neogenin	cd05723	1.1e-05	256	327
Ig	cd00096	2.6e-14	257	324
Ig2_VEGFR	cd04976	8.7e-05	257	329
Ig3_Robo	cd05725	7.1e-05	257	327
Ig2_Follistatin_like	cd05736	3.2e-05	257	330
Ig_Myotilin_C_like	cd05744	0.00014	257	327
Ig_Pro_neuregulin	cd05750	0.00036	257	325
Ig_1	cd05763	1.9e-06	257	328
Ig_Myotilin_C	cd05892	0.00026	257	327
Ig5_Titin_like	cd05747	5e-10	328	416
Ig3_Contactin_like	cd04968	7.8e-08	330	418
Ig3_Contactin-1	cd05851	3e-05	330	418
Ig1_Robo	cd07693	6.1e-06	330	418
Ig1_Contactin	cd04967	2.5e-05	331	415
Ig_TrkABC_d4	cd04972	2.2e-05	331	417
Ig3_NCAM-1_like	cd05730	0.00018	331	420
Ig1_Contactin-1	cd05849	0.00086	331	417
Ig1_Neogenin	cd05722	1.2e-05	332	417
Ig4_Contactin-2-like	cd05728	2.9e-11	334	417
Ig2_Robo	cd05724	7.5e-07	335	417
Ig2_FGFR_like	cd05729	4.8e-05	338	417
Ig2_FGFR	cd05857	1e-05	338	417
Ig3_Peroxidasin	cd05745	9.5e-11	344	417
Ig5_Contactin_like	cd04969	1.4e-11	345	417
Ig4_L1-NrCAM_like	cd04978	2.7e-05	347	418
Ig4_Neogenin	cd05723	1.2e-44	347	417
Ig_Titin_like	cd05748	4.7e-05	347	417
Ig	cd00096	1.5e-13	348	414
Ig3_Robo	cd05725	2.6e-12	348	417
Ig3_L1-CAM_like	cd05731	3e-06	348	418
Ig6_L1-CAM_like	cd05733	8.6e-05	348	417
Ig2_Follistatin_like	cd05736	5.5e-05	348	420
Ig_Myotilin_C_like	cd05744	0.00011	348	417
Ig4_Peroxidasin	cd05746	2.3e-10	348	416
Ig_1	cd05763	2.3e-05	348	418
Ig5_Contactin-1	cd05852	6e-06	348	417
Ig3_L1-CAM	cd05876	0.00021	348	418
Ig_Myotilin_C	cd05892	0.00023	348	417
Ig_Pro_neuregulin	cd05750	0.00061	353	415
FN3	cd00063	5.5e-21	429	521
FN3	cd00063	2e-23	528	617
FN3	cd00063	1.3e-23	622	715
FN3	cd00063	9.6e-15	726	814
FN3	cd00063	9.2e-13	844	939
FN3	cd00063	7.5e-18	945	1041
ig	pfam00047	1.5e-06	154	214
ig	pfam00047	1.2e-08	254	312
ig	pfam00047	5.3e-09	345	402
fn3	pfam00041	2.6e-12	430	514
fn3	pfam00041	8e-17	529	610
fn3	pfam00041	5.6e-18	624	708
fn3	pfam00041	1.9e-07	727	808
fn3	pfam00041	2.7e-05	845	932
fn3	pfam00041	5.2e-14	946	1034
I-set	pfam07679	0.00012	40	136
IG	smart00409	1.7e-11	46	137
IG_like	smart00410	1.7e-11	46	137
IGc2	smart00408	2.2e-05	53	124
I-set	pfam07679	1.9e-12	140	230
IG	smart00409	1.7e-18	146	231
IG_like	smart00410	1.7e-18	146	231
V-set	pfam07686	6.7e-05	148	230
IGc2	smart00408	3e-20	153	219
I-set	pfam07679	8.3e-20	240	327
IG	smart00409	2.4e-20	246	328
IG_like	smart00410	2.4e-20	246	328
V-set	pfam07686	4.1e-05	248	329
IGc2	smart00408	1.5e-13	253	317
I-set	pfam07679	2.5e-19	331	417
IG	smart00409	2e-19	337	418
IG_like	smart00410	2e-19	337	418
IGc2	smart00408	5.4e-13	344	407
FN3	smart00060	3.1e-16	429	511
FN3	smart00060	1.6e-18	528	607
FN3	smart00060	4.3e-17	622	705
FN3	smart00060	1.4e-11	726	805
FN3	smart00060	2.7e-09	844	929
FN3	smart00060	1.3e-13	945	1031
Neogenin_C	pfam06583	2.7e-240	1073	1445

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs2229080	Polymorphism	p.ARG201GLY	N/A
Swiss-Prot	VAR_060259	Polymorphism	p.HIS1191LEU	N/A
dbSNP	rs2278339	Polymorphism	p.ILE759MET	N/A
Swiss-Prot	VAR_060258	Polymorphism	p.LEU679ARG	N/A
Swiss-Prot	VAR_003909	Polymorphism	p.MET168THR	N/A
dbSNP	rs984274	Polymorphism	p.MET1017VAL	N/A
Swiss-Prot	VAR_060257	Polymorphism	p.PHE23LEU	N/A
Swiss-Prot	VAR_035511	Polymorphism	p.PHE1039SER	N/A
Swiss-Prot	VAR_003911	Polymorphism	p.PRO1375HIS	N/A
OMIM	120470.0002	Disease	p.MET168THR	ESOPHAGEAL CARCINOMA, SOMATIC

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

DMDM_info@umbc.edu | 1000 Hilltop Circle, Baltimore, MD 21250 | Department of Biological Sciences | Phone: 410-455-2258