Results for the protein: Q6UW60

Results for the Protein: Q6UW60

296439263

54760

PCSK4

NCBI, UniProt

PCSK4_HUMAN RecName: Full=Proprotein convertase subtilisin/kexin type 4; AltName: Full=Proprotein convertase 4; Short=PC4; Flags: Precursor

			0 3 0 2 1

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Swiss-Prot Protein: Q6UW60

Identical to: NP_060043

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Domains found on the Protein

Domain ↕	CD Accession ↕	E-Value ↕	Start ↕	End ↕
Peptidases_S8_Thermi	cd07484	3.8e-08	117	369
Peptidases_S8_Protei	cd04059	1e-173	118	407
Peptidases_S8_Fervid	cd07485	8.3e-11	125	405
Peptidases_S8_PCSK9_	cd04077	5.8e-05	134	407
Peptidases_S8_11	cd04843	0.00017	139	407
Peptidases_S8_C5a_Pe	cd07475	0.00052	141	441
Peptidases_S8_Kp43_p	cd04842	2.3e-05	144	407
Peptidases_S8_5	cd07489	5.4e-05	145	441
Peptidases_S8_12	cd07480	0.00071	147	425
Peptidases_S8_Autotr	cd04848	2e-12	148	407
Peptidases_S8_subtil	cd07474	1.1e-08	149	439
Peptidases_S8_Bacill	cd07481	3.1e-08	149	407
Peptidases_S8_Subtil	cd07473	2.4e-12	149	407
Peptidases_S8_1	cd07487	1.1e-07	149	407
Peptidases_S8_Subtil	cd07477	3.2e-09	151	405
Peptidases_S8_Lantib	cd07482	4.7e-05	151	405
Peptidases_S8_6	cd07490	8.4e-05	151	407
Peptidases_S8_9	cd07493	5.7e-05	151	407
Peptidases_S8_13	cd07496	2.3e-08	151	405
Peptidases_S8_8	cd07492	0.0002	151	407
Peptidases_S8_S53	cd00306	2.9e-34	152	405
Peptidases_S8_Subtil	cd04847	8.7e-05	152	407
Peptidases_S8_15	cd07498	3.8e-14	152	405
Peptidase_S8	pfam00082	5.4e-117	132	432
COG4935	COG4935	8.8e-06	447	642
P_proprotein	pfam01483	9.1e-41	489	575
FU	smart00261	0.00013	646	694

Table of Mutations found on the Protein

Source ↕	Mut_ID ↕	Class ↕	HGVS ↕	Disease ↕
dbSNP	rs12972390	Polymorphism	p.ARG90HIS	N/A
dbSNP	rs76450268	Polymorphism	p.HIS703TYR	N/A
Swiss-Prot	VAR_061772	Polymorphism	p.THR267MET	N/A

Please Cite: Peterson, T.A., Adadey, A., Santana-Cruz ,I., Sun, Y., Winder A, Kann, M.G., (2010) DMDM: Domain Mapping of Disease Mutations. Bioinformatics 26 (19), 2458-2459.

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