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Results for the Protein: Q15746
300669714

MYLK_HUMAN RecName: Full=Myosin light chain kinase, smooth muscle; Short=MLCK; Short=smMLCK; AltName: Full=Kinase-related protein; Short=KRP; AltName: Full=Telokin; Contains: RecName: Full=Myosin light chain kinase, smooth muscle, deglutamylated form

Known Diseases associated with this Protein:
  AORTIC ANEURYSM, FAMILIAL THORACIC 7
  AORTIC ANEURYSM, FAMILIAL THORACIC 7 (AAT7)
3
29
2
8
22
Tips:
 The Domains on the Default View are decided by the Domain's E-Value.

 Clicking a check box will display or hide the correlated domain.

 To view the Gene page, either click on the link to the left or the blue bar above the Protein's graphic.



Default View:

Ig5_Titin_like - cd05747
Ig1_Robo - cd07693
I-set - pfam07679
Ig2_Robo - cd05724
Ig3_NCAM-1_like - cd05730
IG_like - smart00410
Ig_M-protein_C - cd05891
Ig2_FGFR_like - cd05729
Ig_Myomesin_like_C - cd05737
IG - smart00409
Ig2_FGFR - cd05857
Ig3_Peroxidasin - cd05745
IGc2 - smart00408
ig - pfam00047
Ig4_L1-NrCAM_like - cd04978
Ig_3 - cd05765
Ig_Perlecan_D2_like - cd05743
Ig_Titin_like - cd05748
Ig_Myotilin_C - cd05892
Ig_Palladin_C - cd05893
Ig2_VEGFR-2 - cd05864
Ig3_Robo - cd05725
Ig - cd00096
Ig4_Peroxidasin - cd05746
Ig2_Follistatin_like - cd05736
Ig_Myotilin_C_like - cd05744
Ig2_VEGFR - cd04976
Ig2_VEGFR-1 - cd07702
Ig4_Neogenin - cd05723
Ig5_Contactin_like - cd04969
Ig3_Contactin-1 - cd05851
Ig3_Contactin_like - cd04968
Ig4_Contactin-2-like - cd05728
Ig2_FGFRL1-like - cd05856
Ig5_Contactin-1 - cd05852
V-set - pfam07686
Ig_C5_MyBP-C - cd05894
Ig3_FGFR - cd04974
Ig3_FGFR-2 - cd05858
Ig4_Robo - cd05726
Ig_2 - cd05764
Ig_1 - cd05763
Ig2_PTK7 - cd05760
Ig5_NCAM-1 - cd05869
Ig_Semaphorin_C - cd04979
Ig5_NCAM-1_like - cd05732
Ig_TrkABC_d4 - cd04972
Ig1_Neogenin - cd05722
Ig_Sema4B_like - cd05872
Ig4_NrCAM - cd05868
Ig3_L1-CAM_like - cd05731
Ig_Pro_neuregulin - cd05750
Ig3_L1-CAM - cd05876
Ig1_Contactin - cd04967
Ig8_MLCK - cd05762
Ig2_VEGFR-3 - cd05863
Ig1_FGFR - cd04973
FN3 - cd00063
FN3 - smart00060
fn3 - pfam00041
STKc_TAO1 - cd06635
STKc_ROCK1 - cd05622
STKc_ROCK - cd05596
STKc_ROCK2 - cd05621
STKc_JNK1 - cd07875
STKc_PAK1 - cd06654
STKc_PAK3 - cd06656
STKc_PAK2 - cd06655
STKc_PAK_II - cd06648
STKc_TAO3 - cd06633
STKc_JNK2 - cd07876
STKc_PAK_I - cd06647
STKc_TAO2 - cd06634
STKc_TAO - cd06607
STKc_p38alpha_MAPK14 - cd07877
STKc_JNK3 - cd07874
STKc_PAK5 - cd06658
STKc_myosinIIIB - cd06639
STKc_MAP4K4_6 - cd06636
STKc_myosinIIIA - cd06638
STKc_JNK - cd07850
STKc_STK10_LOK - cd06644
STKc_PAK - cd06614
STKc_PAK4 - cd06657
STKc_p38 - cd07851
STKc_p38delta_MAPK13 - cd07879
STKc_p38gamma_MAPK12 - cd07880
STKc_p38beta_MAPK11 - cd07878
STKc_CDK9 - cd07865
PKc_MKK7 - cd06618
PTKc_HER2 - cd05109
STKc_PAK6 - cd06659
STKc_Sty1_Hog1 - cd07856
STKc_MAP4K3 - cd06645
STKc_MAP4K5 - cd06646
PTKc_EGFR_like - cd05057
STKc_MAPK15 - cd07852
STKc_TNIK - cd06637
PKc_MEK1 - cd06650
PTKc_Ror - cd05048
STKc_ASK - cd06624
STKc_CDK12 - cd07864
PTKc_TrkA - cd05092
PTKc_Ror1 - cd05090
PTKc_Abl - cd05052
PTKc_Ror2 - cd05091
PTKc_Trk - cd05049
PKc_MEK2 - cd06649
PTKc_Fyn_Yrk - cd05070
PTKc_EphR_A2 - cd05063
PTKc_EphR_A10 - cd05064
PTKc_InsR - cd05061
PTKc_Jak_rpt2 - cd05038
PTKc_ALK_LTK - cd05036
PTKc_FAK - cd05056
PTKc_Frk_like - cd05068
PTKc_Yes - cd05069
STKc_SLK - cd06643
STKc_ERK1_2_like - cd07849
PTKc_Lyn - cd05072
PTKc_Hck - cd05073
PTKc_Src - cd05071
STKc_CDK10 - cd07845
PTKc_Csk - cd05082
PTKc_Btk_Bmx - cd05113
PTKc_Tec_Rlk - cd05114
PTKc_HER4 - cd05110
PTKc_EGFR - cd05108
PTKc_EphR_B - cd05065
PTKc_TrkB - cd05093
PKc_MAPKK_Byr1_like - cd06620
PKc_MKK4 - cd06616
STKc_ERK5 - cd07855
STKc_TEY_MAPK_plant - cd07858
STKc_STK25-YSK1 - cd06642
STKc_MST3 - cd06641
STKc_MST4 - cd06640
STKc_BUR1 - cd07866
STKc_MAP4K3_like - cd06613
STKc_CDC2L1 - cd07843
PTKc_InsR_like - cd05032
PTKc_Tie2 - cd05088
STKc_MST1_2 - cd06612
STKc_PFTAIRE2 - cd07870
STKc_PCTAIRE_like - cd07844
STKc_Nek6 - cd08228
STKc_Sid2p_Dbf2p - cd05600
STKc_LATS1 - cd05625
STKc_NDR1 - cd05628
STKc_SLK_like - cd06611
STKc_LATS - cd05598
STKc_MRCK_alpha - cd05623
STKc_NDR_like - cd05599
STKc_CRIK - cd05601
STKc_NDR_like_fungal - cd05629
STKc_MEKK2 - cd06652
STKc_MEKK3_like_1 - cd06653
PKc_MAPKK_plant_like - cd06623
PKc_MKK3_6 - cd06617
PKc_MEK - cd06615
PKc_MAPKK_PBS2_like - cd06622
STKc_PFTAIRE1 - cd07869
PKc_MAPKK - cd06605
STKc_LATS2 - cd05626
STKc_myosinIII_like - cd06608
SPS1 - COG0515
STKc_Nek6_Nek7 - cd08224
PTKc_Itk - cd05112
STKc_phototropin_lik - cd05574
PTKc_Jak1_rpt2 - cd05079
PTKc_EphR_A - cd05066
PTKc_Tec_like - cd05059
PTKc_Lck_Blk - cd05067
STKc_CDKL - cd07833
STKc_NAK1_like - cd06917
PTKc_EphR - cd05033
PTKc_Musk - cd05050
STKc_MST3_like - cd06609
STKc_CdkB_plant - cd07837
STKc_OSR1_SPAK - cd06610
STKc_cPKC_beta - cd05616
STKc_PRKX_like - cd05612
STKc_MRCK_beta - cd05624
STKc_NDR2 - cd05627
PTKc_Chk - cd05083
PKc_MKK5 - cd06619
STKc_PDK1 - cd05581
STKc_PCTAIRE2 - cd07872
STKc_CDK6 - cd07862
STKc_MAST - cd05609
STKc_PCTAIRE1 - cd07873
STKc_CNK2-like - cd08530
STKc_CDK1_euk - cd07861
STKc_CDKL5 - cd07848
STKc_DMPK_like - cd05597
STKc_PKA - cd05580
STKc_CDKL1_4 - cd07847
STKc_cPKC - cd05587
STKc_CDKL2_3 - cd07846
STKc_ROCK_NDR_like - cd05573
STKc_Nek10 - cd08528
STKc_GRK5 - cd05632
STKc_GRK4 - cd05631
STKc_GRK6 - cd05630
STKc_MAPKKK - cd06606
STKc_Cdc7_like - cd06627
STKc_GRK4_like - cd05605
PKc_STE - cd05122
PTK_Ryk - cd05043
PTKc_Tyk2_rpt2 - cd05080
PTKc_Tie1 - cd05089
PTK_HER3 - cd05111
STKc_YSK4 - cd06631
STKc_CCRK - cd07832
STKc_MPK1 - cd07857
STKc_CDK2_3 - cd07860
STKc_NLK - cd07853
STKc_Nek - cd08215
STKc_Nek2 - cd08217
STKc_CDK8 - cd07868
STKc_PCTAIRE3 - cd07871
STKc_MAPK - cd07834
STKc_CDK8_like - cd07842
STKc_CDK7 - cd07841
STKc_CDC2L6 - cd07867
Pkinase - pfam00069
STKc_MOK - cd07831
STKc_CDK4_6_like - cd07838
STKc_MAK_like - cd07830
STKc_CDK_like - cd07829
PKc_MAPKK_Pek1_like - cd06621
STKc_CDK1_like - cd07835
STKc_CDK5 - cd07839
STKc_TDY_MAPK_plant - cd07859
STKc_MAPK4_6 - cd07854
STKc_CDK9_like - cd07840
STKc_MSK2_N - cd05614
STKc_cPKC_alpha - cd05615
STKc_CMGC - cd05118
PTKc_Tyro3 - cd05074
PTKc_Axl_like - cd05035
PTKc_Srm_Brk - cd05148
STKc_Yank1 - cd05578
STKc_MSK1_N - cd05613
STKc_PKN - cd05589
STKc_MSK_N - cd05583
STKc_CDK4 - cd07863
STKc_Pho85 - cd07836
STKc_FA2-like - cd08529
STKc_Nek7 - cd08229
Pkinase_Tyr - pfam07714
TyrKc - smart00219
STYKc - smart00221
STKc_Nek1 - cd08218
STKc_Nek5 - cd08225
STKc_Nek3 - cd08219
STKc_Nek8 - cd08220
STKc_Nek11 - cd08222
STKc_Nek4 - cd08223
STKc_MEKK3 - cd06651
PTKc_Src_like - cd05034
PTKc_RET - cd05045
PTKc_Csk_like - cd05039
STKc_MAPKKK_Byr2_lik - cd06628
PTKc_Jak2_Jak3_rpt2 - cd05081
STKc_p70S6K - cd05584
STKc_RSK_N - cd05582
STKc_SGK3 - cd05604
STKc_SGK2 - cd05603
STKc_SGK - cd05575
STKc_SGK1 - cd05602
STKc_PKB_beta - cd05595
STKc_nPKC_theta_delt - cd05592
STKc_PKB_alpha - cd05594
STKc_aPKC_zeta - cd05617
STKc_aPKC_iota - cd05618
STKc_MEKK1 - cd06630
STKc_MEKK1_plant - cd06632
STKc_MAPKKK_Bck1_lik - cd06629
STKc_nPKC_epsilon - cd05591
STKc_nPKC_theta - cd05619
STKc_nPKC_delta - cd05620
STKc_nPKC_eta - cd05590
STKc_PKB_gamma - cd05593
PTKc_c-ros - cd05044
STKc_aPKC - cd05588
PTKc_Tie - cd05047
PTKc_Fes_like - cd05041
PTKc - cd00192
PTKc_Ack_like - cd05040
PTKc_Met_Ron - cd05058
PTKc_Syk_like - cd05060
STKc_PKC - cd05570
PTKc_Fes - cd05084
PTKc_Syk - cd05116
STKc_PKB - cd05571
PTKc_Aatyk2 - cd05086
PTKc_Fer - cd05085
STKc_MEKK4 - cd06626
PTKc_Zap-70 - cd05115
STKc_GRK - cd05577
STKc_AGC - cd05123
PKc - cd00180
STKc_MAST_like - cd05579
STKc_cGK_PKG - cd05572
STKc_GRK3 - cd05633
STKc_MEKK3_like - cd06625
STKc_Nek9 - cd08221
STKc_beta_ARK - cd05606
STKc_GRK7 - cd05607
STKc_YPK1_like - cd05585
STKc_Sck1_like - cd05586
STKc_GRK1 - cd05608
STKc_Rim15_like - cd05611
S_TKc - smart00220
Ig5_KIRREL3-like - cd05758


Swiss-Prot Protein: Q15746
Identical to: NP_444253
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Domains found on the Protein

Domain ↕CD Accession ↕E-Value ↕Start ↕End ↕
Ig5_Titin_likecd057471.3e-1031122
Ig1_Robocd076932e-0532122
Ig2_Robocd057241.9e-0837123
Ig3_NCAM-1_likecd057302.1e-0538129
Ig2_FGFR_likecd057296.1e-0739123
Ig_Myomesin_like_Ccd057371.8e-0539121
Ig_M-protein_Ccd058915.7e-0639123
Ig2_FGFRcd058573.6e-0640123
Ig3_Peroxidasincd057451.8e-0846123
Ig4_L1-NrCAM_likecd049780.0002647124
Ig_Perlecan_D2_likecd057435.8e-0547123
Ig_3cd057657.5e-0647123
Ig_Titin_likecd057485.5e-0549123
Igcd000962.7e-1450120
Ig2_VEGFRcd049769.8e-0550123
Ig3_Robocd057259.9e-0650123
Ig2_Follistatin_likecd057368.7e-0550126
Ig_Myotilin_C_likecd057447.9e-0550123
Ig4_Peroxidasincd057469.9e-0650122
Ig2_VEGFR-2cd058640.0002550123
Ig_Myotilin_Ccd058920.0001250123
Ig_Palladin_Ccd058938.3e-0650123
Ig2_VEGFR-1cd077020.0003351123
Ig4_Neogenincd057230.0007252123
Ig5_Contactin_likecd049690.0001153123
Ig5_Titin_likecd057473.5e-11158249
Ig3_Contactin_likecd049681.5e-05160251
Ig3_Contactin-1cd058518.4e-05160251
Ig4_Contactin-2-likecd057289.9e-05162250
Ig_M-protein_Ccd058917.1e-05162250
Ig2_FGFRcd058570.00055165250
Ig5_Contactin_likecd049694.4e-06168250
Ig2_FGFR_likecd057291.7e-05168250
Ig_Myomesin_like_Ccd057376.1e-06168250
Ig5_Contactin-1cd058522.1e-05168250
Ig2_FGFRL1-likecd058560.001168250
Ig_C5_MyBP-Ccd058941.8e-05170250
Ig3_Peroxidasincd057459.3e-08174250
Ig3_FGFRcd049740.00093175251
Ig4_Robocd057267.8e-05175259
Ig_2cd057640.00022175250
Ig_3cd057652.7e-05175250
Ig3_FGFR-2cd058583.9e-05175251
Igcd000963.4e-11178247
Ig3_Robocd057254.7e-05178250
Ig_1cd057631.3e-07178251
Ig_Myotilin_C_likecd057445.3e-05179250
Ig4_Peroxidasincd057461.7e-08179249
Ig2_PTK7cd057600.00078179255
Ig_Myotilin_Ccd058923.1e-05179250
Ig_Palladin_Ccd058936.2e-06179250
Ig4_Neogenincd057231.4e-09180250
Ig_Titin_likecd057483.7e-06183250
Ig5_NCAM-1cd058690.00034412504
Ig4_Contactin-2-likecd057280.00012415504
Ig_Semaphorin_Ccd049790.00069418507
Ig5_NCAM-1_likecd057320.00024418504
Ig2_FGFR_likecd057291.3e-08420504
Ig2_FGFRL1-likecd058560.00017422504
Ig2_FGFRcd058573.6e-05425504
Ig3_Peroxidasincd057451.2e-05427504
Ig5_Contactin_likecd049690.00086428504
Ig4_L1-NrCAM_likecd049780.0002428505
Ig_3cd057658.7e-07428504
Ig4_Neogenincd057230.00025430504
Ig_Titin_likecd057480.00015430504
Igcd000967.3e-09431501
Ig3_Robocd057253.9e-06431504
Ig_Myotilin_C_likecd057440.00017431504
Ig2_PTK7cd057601e-06431507
Ig_1cd057631.5e-05431505
Ig_Myotilin_Ccd058928e-05431504
Ig_Palladin_Ccd058931.8e-05431504
Ig3_NCAM-1_likecd057300.00067513603
Ig3_Contactin-1cd058514.1e-07513601
Ig3_Contactin_likecd049684.4e-07514601
Ig_TrkABC_d4cd049720.00029514600
Ig1_Neogenincd057220.00032515600
Ig4_Contactin-2-likecd057281.7e-05515600
Ig_Semaphorin_Ccd049790.00032518603
Ig_Sema4B_likecd058720.00012518603
Ig2_FGFR_likecd057291.4e-06520600
Ig2_Robocd057241.6e-08521600
Ig2_FGFRcd058570.00022521600
Ig2_FGFRL1-likecd058560.001523600
Ig3_Peroxidasincd057458e-06527600
Ig5_Contactin_likecd049690.00015528600
Ig4_L1-NrCAM_likecd049786.7e-06528601
Ig_Perlecan_D2_likecd057439.9e-07528600
Ig_3cd057650.00019528600
Ig3_FGFR-2cd058580.00016528601
Ig4_NrCAMcd058680.00016528601
Ig4_Neogenincd057233e-11530600
Ig_Titin_likecd057480.00056530600
Igcd000961.9e-13531597
Ig3_Robocd057252e-06531600
Ig3_L1-CAM_likecd057311.9e-05531601
Ig_Myotilin_C_likecd057440.00047531600
Ig4_Peroxidasincd057467.2e-07531599
Ig_Pro_neuregulincd057508.6e-05531598
Ig2_PTK7cd057602.2e-05531605
Ig3_L1-CAMcd058763.9e-05531601
Ig_Palladin_Ccd058930.00089531600
Ig2_Follistatin_likecd057366.1e-05533603
Ig_1cd057633.1e-07533601
Ig3_Contactin-1cd058510.00019621713
Ig3_Contactin_likecd049685.9e-06622713
Ig1_Contactincd049674.5e-05623709
Ig8_MLCKcd057624.1e-05623720
Ig1_Neogenincd057220.00033624712
Ig_Myomesin_like_Ccd057372e-07625712
Ig_M-protein_Ccd058911.3e-08625712
Ig2_Robocd057247.1e-07630712
Ig2_FGFR_likecd057295.9e-07632712
Ig2_FGFRL1-likecd058562.5e-05632712
Ig2_FGFRcd058572.7e-05633712
Ig3_Peroxidasincd057455.6e-05636712
Ig5_Contactin_likecd049690.00075637712
Ig4_L1-NrCAM_likecd049784.2e-05637713
Ig4_Robocd057265e-05637721
Ig_Perlecan_D2_likecd057431.9e-05637712
Ig_3cd057654.3e-05637712
Ig4_Neogenincd057235.5e-11639712
Ig_Titin_likecd057483.9e-06639712
Igcd000963.3e-13640709
Ig2_VEGFRcd049763.3e-06640712
Ig3_Robocd057252.8e-07640712
Ig2_Follistatin_likecd057362.7e-05640715
Ig_Myotilin_C_likecd057440.00014640712
Ig4_Peroxidasincd057461.6e-09640711
Ig_1cd057631e-06640713
Ig2_VEGFR-3cd058636.5e-06640712
Ig_Myotilin_Ccd058920.00066640712
Ig_Palladin_Ccd058930.00039640712
Ig5_Titin_likecd057476.3e-09719810
Ig3_NCAM-1_likecd057300.00016720814
Ig2_FGFR_likecd057291.1e-05727809
Ig2_FGFRL1-likecd058561.6e-05727809
Ig3_Peroxidasincd057450.00067735811
Ig4_Neogenincd057230.00041737811
Ig_Titin_likecd057481.8e-05737811
Igcd000961.3e-08738808
Ig4_Peroxidasincd057466.3e-05738810
Ig2_PTK7cd057601.3e-05738816
Ig2_VEGFR-3cd058630.00035738813
Ig1_Neogenincd057220.0007410991187
Ig2_FGFRcd058570.0007711021187
Ig2_FGFR_likecd057293.1e-0511041187
Ig_Myomesin_like_Ccd057376.6e-0511041187
Ig1_FGFRcd049730.0006311051187
Ig3_Peroxidasincd057450.0009411111187
Ig5_Contactin_likecd049698.1e-0611121187
Ig4_Neogenincd057233.2e-1111141187
Igcd000969.1e-0911151184
Ig3_Robocd057250.0004811151187
Ig4_Peroxidasincd057462.7e-0511151186
Ig_Myotilin_Ccd058920.0006411151187
Ig_Palladin_Ccd058930.0005911151187
Ig5_Titin_likecd057476e-0612351326
Ig8_MLCKcd057625.4e-8312381335
Ig2_FGFR_likecd057290.0003612441327
Ig_Titin_likecd057482.1e-0512541327
Igcd000960.0003812551324
FN3cd000632e-2313311423
STKc_TAO1cd066352.4e-0614311742
STKc_ROCKcd055961.8e-0714331761
STKc_ROCK2cd056213.3e-0814331770
STKc_ROCK1cd056225.4e-0714331774
STKc_JNK1cd078750.000214351764
STKc_PAK1cd066543.3e-0814401735
STKc_PAK2cd066554.5e-0914411740
STKc_PAK3cd066567.3e-0914411742
STKc_TAO3cd066336.7e-0514421742
STKc_PAK_IIcd066483.1e-1014421732
STKc_JNK2cd078761.9e-0514431765
STKc_TAOcd066078.7e-0814441769
STKc_TAO2cd066349e-0714441752
STKc_PAK_Icd066479.3e-1514441741
STKc_PAK5cd066585.1e-0714461740
STKc_JNK3cd078745.6e-0514461774
STKc_p38alpha_MAPK14cd078777e-0614461804
STKc_MAP4K4_6cd066363.6e-0614471719
STKc_myosinIIIAcd066381.7e-0814471719
STKc_myosinIIIBcd066392.5e-0814471720
STKc_JNKcd078505.4e-0714481753
STKc_PAKcd066142.2e-1914491732
STKc_STK10_LOKcd066441.6e-1014491739
STKc_PAK4cd066571.1e-0614491737
STKc_p38cd078511.3e-1014491747
STKc_p38beta_MAPK11cd078783.2e-0614491771
STKc_p38delta_MAPK13cd078796.1e-0514491749
STKc_p38gamma_MAPK12cd078802.1e-0714491783
STKc_CDK9cd078651.4e-0714501719
PKc_MKK7cd066181.8e-1114511738
PTKc_HER2cd051090.0006714521702
STKc_PAK6cd066592.5e-0914521742
STKc_MAP4K3cd066451e-0814531718
STKc_MAP4K5cd066469.2e-0814531718
STKc_Sty1_Hog1cd078563.3e-0614531743
PTKc_EGFR_likecd050572.5e-0514551702
STKc_MAPK15cd078528.3e-0914561742
PTKc_Rorcd050481.6e-0814571703
PTKc_Trkcd050498.9e-0714571701
PTKc_Ablcd050521.2e-0714571721
PTKc_Ror1cd050901.6e-0614571711
PTKc_Ror2cd050911.3e-0514571711
PTKc_TrkAcd050920.0001214571710
STKc_ASKcd066243.4e-2014571719
STKc_TNIKcd066375.6e-0814571719
PKc_MEK1cd066500.0004414571785
PKc_MEK2cd066493.9e-0514571781
STKc_CDK12cd078641.4e-1014571719
PTKc_ALK_LTKcd050361.4e-0614581694
PTKc_FAKcd050562.6e-0914581704
PTKc_Jak_rpt2cd050383.7e-0614581696
PTKc_InsRcd050610.0001714581713
PTKc_EphR_A2cd050633.2e-0514581704
PTKc_EphR_A10cd050640.0001414581723
PTKc_Frk_likecd050683.9e-1214581723
PTKc_Yescd050691.8e-0614581718
PTKc_Fyn_Yrkcd050701.3e-0614581723
PTKc_Srccd050718.8e-0614581720
PTKc_Hckcd050738.8e-0814581718
PTKc_Lyncd050725.3e-0814581718
STKc_SLKcd066434.8e-1714581737
STKc_ERK1_2_likecd078491.3e-0714581746
STKc_CDK10cd078455.5e-0814581726
PTKc_EphR_Bcd050651.3e-0614591721
PTKc_Cskcd050820.0009114591717
PTKc_TrkBcd050930.0001214591709
PTKc_EGFRcd051080.0001414591760
PTKc_HER4cd051100.0002514591731
PTKc_Btk_Bmxcd051133.1e-0814591718
PTKc_Tec_Rlkcd051144.1e-0714591715
PKc_MAPKK_Byr1_likecd066201.1e-0714591732
PKc_MKK4cd066162.4e-0614591736
STKc_MST4cd066407.1e-0914591740
STKc_MST3cd066419.2e-0914591740
STKc_STK25-YSK1cd066424.7e-1014591740
STKc_ERK5cd078556.5e-0814591758
STKc_TEY_MAPK_plantcd078585.5e-0714591765
STKc_BUR1cd078666.4e-1114591719
PTKc_InsR_likecd050322.8e-0514601701
PTKc_Tie2cd050888.3e-0514601723
STKc_MST1_2cd066121.4e-1414601719
STKc_MAP4K3_likecd066132.8e-1314601718
STKc_CDC2L1cd078431.5e-1114601719
STKc_PCTAIRE_likecd078449.9e-0814601750
STKc_PFTAIRE2cd078701.7e-0514601719
STKc_Nek6cd082281.1e-1514601722
PTKc_Tec_likecd050591.7e-0614611693
PTKc_EphR_Acd050663.7e-0514611721
PTKc_Lck_Blkcd050679.1e-0714611743
PTKc_Jak1_rpt2cd050790.0004114611727
PTKc_Itkcd051121.5e-0714611704
STKc_phototropin_likcd055742.2e-1314611734
STKc_LATScd055983.9e-0814611811
STKc_CRIKcd056013.9e-1314611761
STKc_NDR_likecd055994.9e-0714611759
STKc_Sid2p_Dbf2pcd056007.7e-1114611771
STKc_LATS1cd056250.0002814611764
STKc_NDR1cd056282.1e-0714611802
STKc_MRCK_alphacd056232.1e-0614611761
STKc_NDR_like_fungalcd056291.4e-0514611787
STKc_LATS2cd056260.0002314611796
PKc_MAPKKcd066054.7e-1014611724
STKc_myosinIII_likecd066081.1e-1114611719
STKc_SLK_likecd066111.5e-1014611734
PKc_MEKcd066151.4e-0714611736
PKc_MKK3_6cd066173.7e-0714611737
PKc_MAPKK_plant_likecd066232.2e-1614611725
STKc_MEKK2cd066527.5e-0814611720
STKc_MEKK3_like_1cd066534.9e-0914611719
PKc_MAPKK_PBS2_likecd066225.3e-0914611771
STKc_PFTAIRE1cd078691.3e-0514611722
STKc_Nek6_Nek7cd082241.4e-1114611722
SPS1COG05152.4e-5614611865
PTKc_EphRcd050333.1e-0614621696
PTKc_Muskcd050501.1e-0514621716
PTKc_Chkcd050830.00114621722
STKc_ROCK_NDR_likecd055731.5e-1314621760
STKc_PKAcd055801.4e-1514621754
STKc_PDK1cd055813e-2814621719
STKc_DMPK_likecd055975.2e-0814621760
STKc_cPKCcd055871.2e-1414621779
STKc_MASTcd056091.2e-1614621768
STKc_PRKX_likecd056122e-1414621740
STKc_cPKC_betacd056161.1e-0714621798
STKc_MRCK_betacd056242.7e-0614621780
STKc_NDR2cd056271.9e-0514621802
STKc_OSR1_SPAKcd066101.5e-1114621719
PKc_MKK5cd066191.8e-0514621743
STKc_MST3_likecd066094.5e-1514621740
STKc_NAK1_likecd069172.9e-0914621740
STKc_CDKLcd078331.6e-1214621719
STKc_CdkB_plantcd078371.8e-1314621720
STKc_CDKL1_4cd078471.4e-1014621719
STKc_CDKL2_3cd078467.6e-1014621719
STKc_CDKL5cd078488.6e-0614621719
STKc_CDK1_eukcd078618.8e-1014621750
STKc_CDK6cd078620.0003714621731
STKc_PCTAIRE2cd078721.7e-0514621765
STKc_PCTAIRE1cd078731.1e-0514621733
STKc_CNK2-likecd085304.9e-1214621719
PTK_Rykcd050430.0002314631699
PTKc_Tyk2_rpt2cd050804e-0514631741
PTKc_Tie1cd050891.1e-0514631741
PTK_HER3cd051110.0008414631702
PKc_STEcd051229.3e-2814631718
STKc_GRK4_likecd056053.6e-1714631739
STKc_GRK4cd056316.7e-1114631739
STKc_GRK5cd056322.9e-1314631744
STKc_GRK6cd056307e-0914631739
STKc_MAPKKKcd066066e-3114631719
STKc_Cdc7_likecd066272.1e-2014631719
STKc_YSK4cd066312.2e-1314631719
STKc_CCRKcd078325.9e-1414631720
STKc_MAPKcd078343.4e-0914631743
STKc_CDK8_likecd078424.1e-0914631719
STKc_CDK7cd078411.2e-1414631732
STKc_CDC2L6cd078670.0009814631778
STKc_PCTAIRE3cd078711.6e-0714631719
STKc_CDK8cd078680.0002214631782
STKc_CDK2_3cd078608.7e-0714631750
STKc_MPK1cd078572.8e-0814631755
STKc_NLKcd078532.8e-0614631796
STKc_Nekcd082155e-2514631719
STKc_Nek2cd082171.3e-1314631719
STKc_Nek10cd085282.2e-0914631722
PTKc_Axl_likecd050350.0002914641708
PTKc_Tyro3cd050740.0001914641721
STKc_CMGCcd051184.3e-1614641719
PTKc_Srm_Brkcd051481.5e-0814641711
STKc_Yank1cd055781.3e-1514641719
STKc_MSK_Ncd055831.1e-1414641737
STKc_PKNcd055891.1e-0914641800
STKc_MSK1_Ncd056136.2e-1414641738
STKc_cPKC_alphacd056151.9e-0914641768
STKc_MSK2_Ncd056141.5e-1114641780
PKc_MAPKK_Pek1_likecd066219.9e-1014641732
STKc_CDK_likecd078295.3e-1614641719
STKc_MAK_likecd078303.9e-1314641719
STKc_CDK4_6_likecd078381.9e-1014641719
STKc_CDK1_likecd078352.6e-1014641750
STKc_CDK5cd078391.2e-0814641719
STKc_CDK9_likecd078403e-1314641719
STKc_MAPK4_6cd078542.8e-0614641744
STKc_TDY_MAPK_plantcd078595.8e-0814641805
STKc_MOKcd078311.7e-1114641719
STKc_CDK4cd078631.1e-0614641719
STKc_Pho85cd078361.7e-0914641719
STKc_Nek3cd082192.4e-1614641719
STKc_Nek8cd082202.5e-1014641719
STKc_Nek11cd082225.8e-1314641719
STKc_Nek4cd082231.6e-1114641719
STKc_Nek5cd082253.2e-2514641719
STKc_Nek1cd082184.2e-2214641719
STKc_Nek7cd082291.7e-1114641722
STKc_FA2-likecd085293.2e-1214641719
PTKc_Src_likecd050343.5e-1014651695
PTKc_Csk_likecd050390.0001214651676
PTKc_RETcd050450.0003614651702
STKc_MEKK3cd066519.9e-1114651721
PTKc_Jak2_Jak3_rpt2cd050812.1e-0614661712
STKc_MAPKKK_Byr2_likcd066288.8e-2114661719
STKc_p70S6Kcd055842.2e-2314671801
STKc_RSK_Ncd055824.9e-1914671795
PTKccd001928.9e-1114681718
PTKc_Ack_likecd050405.2e-1014681694
PTKc_Fes_likecd050416.8e-1014681694
PTKc_Tiecd050474.1e-0514681722
PTKc_c-roscd050441.1e-0614681716
PTKc_Syk_likecd050603.8e-0814681697
PTKc_Met_Roncd050580.0008314681698
PTKc_Fescd050846.7e-0814681719
PTKc_Fercd050852.3e-0714681697
PTKc_Aatyk2cd050860.0008314681739
PTKc_Sykcd051167.2e-0814681719
STKc_PKCcd055702.4e-1314681740
STKc_PKBcd055711.6e-1814681783
STKc_aPKCcd055881.2e-0914681793
STKc_nPKC_etacd055904.7e-0814681776
STKc_nPKC_theta_deltcd055922.7e-1414681780
STKc_PKB_gammacd055939.3e-1114681771
STKc_PKB_alphacd055943.9e-1214681773
STKc_PKB_betacd055959.8e-1014681784
STKc_SGK1cd056022.1e-0814681781
STKc_SGK2cd056039e-1014681791
STKc_SGK3cd056046.1e-0714681781
STKc_SGKcd055752.8e-0914681781
STKc_aPKC_zetacd056176.4e-0814681771
STKc_aPKC_iotacd056181.6e-0714681765
STKc_nPKC_thetacd056193.2e-1014681780
STKc_nPKC_deltacd056201.2e-0514681780
STKc_nPKC_epsiloncd055918.6e-1014681779
STKc_MAPKKK_Bck1_likcd066298.3e-1014681719
STKc_MEKK1cd066303e-1114681720
STKc_MEKK1_plantcd066321.1e-1514681719
PTKc_Zap-70cd051153.3e-0714691722
STKc_MEKK4cd066261.5e-1514691719
PKccd001805.1e-7014701717
STKc_AGCcd051234.2e-3114701719
STKc_cGK_PKGcd055722.2e-1614701724
STKc_GRKcd055773.9e-1214701734
STKc_MAST_likecd055791.1e-1914701723
STKc_YPK1_likecd055853.8e-1114701777
STKc_Sck1_likecd055862.3e-0914701809
STKc_GRK1cd056088.6e-1814701738
STKc_GRK7cd056078.7e-1214701743
STKc_beta_ARKcd056061.7e-0814701743
STKc_GRK3cd056331.3e-0614701742
STKc_MEKK3_likecd066258.9e-1714701719
STKc_Nek9cd082215.5e-1114701719
STKc_Rim15_likecd056116.6e-0614731722
Ig3_NCAM-1_likecd057300.0001518041902
Ig4_Contactin-2-likecd057280.0001318101899
Ig5_Titin_likecd057477.6e-0518101898
Ig_Myomesin_like_Ccd057373.2e-0618121899
Ig_M-protein_Ccd058911.3e-0818121899
Ig2_FGFR_likecd057291.5e-0718151899
Ig2_FGFRL1-likecd058563.5e-0518151899
Ig2_Robocd057242.4e-0818161899
Ig5_KIRREL3-likecd057580.0001218161898
Ig2_FGFRcd058570.0001718161899
Ig3_Peroxidasincd057454.6e-0718221899
Ig5_Contactin_likecd049699.9e-0618231899
Ig_2cd057640.0005618231899
Ig_Titin_likecd057485.7e-0618251899
Igcd000965.2e-1418261896
Ig2_VEGFRcd049767.9e-0618261899
Ig3_Robocd057259.7e-0718261899
Ig2_Follistatin_likecd057360.0001718261902
Ig_Myotilin_C_likecd057444.2e-0718261899
Ig4_Peroxidasincd057463.2e-0718261898
Ig_1cd057630.0001118261900
Ig_Myotilin_Ccd058923.9e-0918261899
Ig_Palladin_Ccd058933e-0618261899
Ig2_VEGFR-1cd077020.0001618271899
Ig4_Neogenincd057232.3e-0718281899
Ig_Pro_neuregulincd057500.0001718301897
igpfam000471.4e-0547108
igpfam000473.1e-09175235
igpfam000471.5e-05428489
igpfam000471.5e-08528585
igpfam000475.6e-09637697
igpfam000470.000911121172
fn3pfam000413.3e-2013321416
Pkinasepfam000691.4e-10114641719
igpfam000477.6e-0818231884
I-setpfam076795.6e-3233123
IGsmart004092.6e-2039124
IG_likesmart004102.6e-2039124
IGc2smart004086.4e-1346113
I-setpfam076795.3e-34161250
IGsmart004092.2e-19167251
IG_likesmart004102.2e-19167251
V-setpfam076860.00021169250
IGc2smart004084.4e-10174240
I-setpfam076792.6e-27414504
IGsmart004094.4e-19420505
IG_likesmart004104.4e-19420505
V-setpfam076860.00038422504
IGc2smart004085.3e-13427494
I-setpfam076791.1e-25514600
IGsmart004095.6e-18520601
IG_likesmart004105.6e-18520601
IGc2smart004085e-18527590
I-setpfam076791.8e-30623712
IGsmart004092.4e-20629713
IG_likesmart004102.4e-20629713
IGc2smart004082.2e-11636702
I-setpfam076794e-19721811
IGsmart004098.2e-16727812
IG_likesmart004108.2e-16727812
IGc2smart004085.6e-05734801
I-setpfam076791e-2310981187
IGsmart004093.1e-1611041188
IG_likesmart004103.1e-1611041188
V-setpfam076860.0001211061187
IGc2smart004083.4e-1011111177
I-setpfam076793.7e-2012381327
IGsmart004094.4e-1212441328
IG_likesmart004104.4e-1212441328
FN3smart000602.6e-1713311413
Pkinase_Tyrpfam077149.1e-1414641708
TyrKcsmart002194.7e-1314641719
STYKcsmart002216.9e-8314641719
S_TKcsmart002203e-9314741719
I-setpfam076796.5e-4718091899
IGsmart004091.3e-1918151900
IG_likesmart004101.3e-1918151900
IGc2smart004081.2e-1918221889

Table of Mutations found on the Protein

Source ↕Mut_ID ↕Class ↕HGVS ↕Disease ↕
Swiss-ProtVAR_065576Polymorphismp.ALA1754THRN/A
Swiss-ProtVAR_040856Polymorphismp.ALA701THRN/A
Swiss-ProtVAR_065570Polymorphismp.ALA128VALN/A
Swiss-ProtVAR_040858Polymorphismp.ALA1527VALN/A
Swiss-ProtVAR_057108Polymorphismp.ARG845CYSN/A
dbSNPrs77323602 Polymorphismp.ARG506GLYN/A
Swiss-ProtVAR_040852Polymorphismp.ARG607GLYN/A
Swiss-ProtVAR_040849Polymorphismp.ARG378HISN/A
dbSNPrs3732487 Polymorphismp.ASP914GLUN/A
Swiss-ProtVAR_065571Polymorphismp.GLN133HISN/A
dbSNPrs12172926 Polymorphismp.GLU1009ASPN/A
Swiss-ProtVAR_065575Polymorphismp.GLU1399LYSN/A
dbSNPrs3732486 Polymorphismp.LEU861PRON/A
Swiss-ProtVAR_040850Polymorphismp.MET405VALN/A
Swiss-ProtVAR_040853Polymorphismp.PRO652ALAN/A
Swiss-ProtVAR_065572Polymorphismp.PRO160ARGN/A
dbSNPrs28497577 Polymorphismp.PRO21HISN/A
Swiss-ProtVAR_040859Polymorphismp.PRO1588LEUN/A
Swiss-ProtVAR_057107Polymorphismp.PRO336LEUN/A
dbSNPrs9840993 Polymorphismp.PRO147SERN/A
Swiss-ProtVAR_040851Polymorphismp.PRO443SERN/A
Swiss-ProtVAR_065577Diseasep.SER1759PROAortic aneurysm, familial thoracic 7 (AAT7)
Swiss-ProtVAR_065573Polymorphismp.THR1085ALAN/A
Swiss-ProtVAR_040848Polymorphismp.THR276ALAN/A
Swiss-ProtVAR_040855Polymorphismp.THR692METN/A
Swiss-ProtVAR_040854Polymorphismp.TRP656CYSN/A
dbSNPrs3796164 Polymorphismp.VAL261ALAN/A
Swiss-ProtVAR_065574Polymorphismp.VAL1213METN/A
Swiss-ProtVAR_040857Polymorphismp.VAL709METN/A
dbSNPrs34542174 Polymorphismp.VAL877METN/A
OMIM600922.0002 Diseasep.ARG1480TERAORTIC ANEURYSM, FAMILIAL THORACIC 7
OMIM600922.0001 Diseasep.SER1759PROAORTIC ANEURYSM, FAMILIAL THORACIC 7



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